Association of ABCB1 genetic polymorphisms with susceptibility to colorectal cancer and therapeutic prognosis

Pharmacogenomics

Volumn 14, Issue 8, 2013, Pages 897-911

  Wu, Huizhe ^a   Kang, Hui ^a   Liu, Yong ^a   Xiao, Qinghuan ^a   Zhang, Yining ^a   Sun, Mingjun ^a   Liu, Duo ^a   Wang, Zhe ^a   Zhao, Haishan ^a   Yao, Weifan ^a   Jia, Tianhong ^a   Wang, Enhua ^a   Zheng, Zhihong ^a   Wei, Minjie ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

ABCB1; colorectal cancer; fluorouracil; genetic polymorphisms; haplotype; oxaliplatin; prognosis; susceptibility

Indexed keywords

CAPECITABINE; CISPLATIN; FLUOROURACIL; FOLINIC ACID; MULTIDRUG RESISTANCE PROTEIN 1; OXALIPLATIN;

ABCB1 GENE; ADULT; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER RISK; CANCER SUSCEPTIBILITY; CASE CONTROL STUDY; COLORECTAL CANCER; CONTINUOUS INFUSION; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PHARMACOGENOMICS; PROGRESSION FREE SURVIVAL; RECURRENCE FREE SURVIVAL;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; DISEASE-FREE SURVIVAL; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; ORGANOPLATINUM COMPOUNDS; P-GLYCOPROTEIN; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS;

EID: 84878856110     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.13.78     Document Type: Article

References (48)

1. Pourhoseingholi MA. Increased burden of colorectal cancer in Asia. World J. Gastrointest. Oncol. 4(4), 68-70 (2012).
2. Brandstedt J, Wangefjord S, Nodin B et al. Gender, anthropometric factors and risk of colorectal cancer with particular reference to tumour location and TNM stage: a cohort study. Biol. Sex Differ. 3(1), 23 (2012).
3. Goldstein DB, Cavalleri GL. Genomics: understanding human diversity. Nature 437(7063), 1241-1242 (2005).
4. Midgley R, Kerr DJ. Adjuvant chemotherapy for stage II colorectal cancer: the time is right! Nat. Clin. Pract. Oncol. 2(7), 364-369 (2005). (Pubitemid 43118123)
5. Crea F, Nobili S, Paolicchi E et al. Epigenetics and chemoresistance in colorectal cancer: an opportunity for treatment tailoring and novel therapeutic strategies. Drug Resist. Updat. 14(6), 280-296 (2011).
6. Ferguson LR, De Flora S. Multiple drug resistance, antimutagenesis and anticarcinogenesis. Mutat. Res. 591(1-2), 24-33 (2005). (Pubitemid 41654837)
7. Zhou SF. Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition. Xenobiotica 38(7-8), 802-832 (2008).
8. Leonessa F, Clarke R. ATP binding cassette transporters and drug resistance in breast cancer. Endocr. Relat. Cancer 10, 43-73 (2003). (Pubitemid 36457239)
9. Gottesman MM, Fojo T, Bates SE. Multidrug resistance in cancer: role of ATP-dependent transporters. Nat. Rev. Cancer 2(1), 48-58 (2002). (Pubitemid 37328807)
10. Scotto KW, Johnson RA. Transcription of the multidrug resistance gene MDR1: a therapeutic target. Mol. Interv. 1(2), 117-125 (2001).
11. George J, Dharanipragada K, Krishnamachari S et al. A single-nucleotide polymorphism in the ABCB1 gene as a predictor of response to neoadjuvant chemotherapy in breast carcinoma. Clin. Breast Carcinoma 9(3), 161-165 (2009).
12. Andersen V, Ostergaard M, Christensen J et al. Polymorphisms in the xenobiotic transporter multidrug resistance 1 (MDR1) and interaction with meat intake in relation to risk of colorectal cancer in a Danish prospective case-cohort study. BMC Cancer 21(9), 407 (2009).
13. Gervasini G, Carrillo JA, Garcia M et al. Adenosine triphosphate-binding cassette B1 (ABCB1; multidrug resistance 1) G2677T/A gene polymorphism is associated with high risk of lung cancer. Cancer 107(12), 2850-2857 (2006). (Pubitemid 44937039)
14. Goreva OB, Grishanova AY, Mukhin OV et al. Possible prediction of the efficiency of chemotherapy in patients with lymphoproliferative diseases based on ABCB1 gene G2677T and C3435T polymorphisms. Bull. Exp. Biol. Med. 136(2), 183-185 (2003). (Pubitemid 38132989)
15. Gréen H, Söderkvist P, Rosenberg P et al. mdr-1 single nucleotide polymorphisms in ovarian cancer tissue: G2677T/A correlates with response to paclitaxel chemotherapy. Clin. Cancer Res. 12(3), 854-859 (2006). (Pubitemid 43259868)
16. Han JY, Lim HS, Yoo YK et al. Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer. Cancer 110(1), 138-147 (2007).
17. Huang MY, Wang YH, Chen FM et al. Multiple genetic polymorphisms of GSTP1 313AG, ABCB1 3435CC, and MTHFR 677CC highly correlated with early relapse of breast carcinoma patients in Taiwan. Ann. Surg. Oncol. 15(3), 872-880 (2008).
18. Kafka A, Sauer G, Jaeger C et al. Polymorphism C3435T of the MDR-1 gene predicts response to preoperative chemotherapy in locally advanced breast carcinoma. Int. J. Oncol. 22(5), 1117-1121 (2003).
19. Oselin K, Gerloff T, Mrozikiewicz PM et al. ABCB1 polymorphisms G2677T in exon 21 and C3435T in exon 26 fail to affect rhodamine 123 efflux in peripheral blood lymphocytes. Fundam. Clin. Pharmacol. 17(4), 463-469 (2003). (Pubitemid 36920648)
20. Pan JH, Han JX, Wu JM et al. ABCB1 single nucleotide polymorphism G2677T/A and haplotype are correlated with response to docetaxel-cisplatin chemotherapy in patients with non-small-cell lung cancer. Respiration 78(1), 49-55 (2009).
21. Rodrigues FFO, Santos RE, Melo MB et al. Correlation of polymorphism C3435T of the MDR-1 gene and the response of primary chemotherapy in women with locally advanced breast carcinoma. Genet. Mol. Res. 7(1), 177-183 (2008). (Pubitemid 351559453)
22. Kurzawski M, Dro?dzik M, Suchy J et al. Polymorphism in the P-glycoprotein drug transporter ABCB1 gene in colon cancer patients. Eur. J. Clin. Pharmacol. 61(5-6), 389-394 (2005). (Pubitemid 41569314)
23. Siegsmund M, Brinkmann U, Scháffeler E et al. Association of the P-glycoprotein transporter ABCB1 (C3435T) polymorphism with the susceptibility to renal epithelial tumors. J. Am. Soc. Nephrol. 13(7), 1847-1854 (2002). (Pubitemid 34700609)
24. Bae SY, Choi SK, Kim KR et al. Effects of genetic polymorphisms of MDR1, FMO3 and CYP1A2 on susceptibility to colorectal cancer in Koreans. Cancer Sci. 97, 774-779 (2006).
25. Kurzawski M, Drozdzik M, Suchy J et al. Polymorphism in the P-glycoprotein drug transporter MDR1 gene in colon cancer patients. Eur. J. Clin. Pharmacol. 61, 389-394 (2005). (Pubitemid 41569314)
26. Leschziner GD, Andrew T, Pirmohamed M et al. ABCB1 genotype and PGP expression, function and therapeutic drug response: a critical review and recommendations for future research. Pharmacogenomics J. 7(3), 154-179 (2007). (Pubitemid 46794925)
27. Fromm MF. The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans. Adv. Drug Deliv. Rev. 54, 1295-1310 (2002). (Pubitemid 35284254)
28. Fung KL, Gottesman MM. A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function. Biochim. Biophys. Acta 1794(5), 860-871 (2009).
29. Kimchi-Sarfaty C, Oh JM, Kim IW et al. A 'silent' polymorphism in the ABCB1 gene changes substrate specificity. Science 315(5811), 525-528 (2007). (Pubitemid 46175758)
30. Campa D, Sainz J, Pardini B et al. A comprehensive investigation on common polymorphisms in the MDR1/ABCB1 transporter gene and susceptibility to colorectal cancer. PLoS ONE 7(3), e32784 (2012).
31. Ashariati A. Polymorphism C3435T of the MDR-1 gene predicts response to preoperative chemotherapy in locally advanced breast carcinoma with Her2/neu expression. Acta Med. Indones. 40(4), 187-191 (2008).
32. Sohn JW, Lee SY, Lee SJ et al. ABCB1 polymorphisms predict the response to etoposide cisplatin combination chemotherapy in small cell lung cancer. Jap. J. Clin. Oncol. 36(3), 137-141 (2006).
33. Kimchi-Sarfaty C, Marple AH, Shinar S et al. Ethnicity-related polymorphisms and haplotypes in the human ABCB1 gene. Pharmacogenomics 8(1), 29-39 (2007). (Pubitemid 46157755)
34. Komar AA. SNPs, silent but not invisible. Science 315, 466-467 (2007). (Pubitemid 46178389)
35. Khedri A, Nejat-Shokouhi A, Salek R et al. Association of the colorectal cancer and MDR1 gene polymorphism in an Iranian population. Mol. Biol. Rep. 2939-2943 (2010).
36. Balcerczak E, Panczyk M, Piaskowski S et al. ABCB1/MDR1 gene polymorphisms as a prognostic factor in colorectal cancer. Int. J. Colorectal Dis. 25(10), 1167-1176 (2010).
37. Komoto C, Nakamura T, Sakaeda T et al. MDR1 haplotype frequencies in Japanese and Caucasian, and in Japanese patients with colorectal cancer and esophageal cancer. Drug Metab. Pharmacokinet. 21, 126-132 (2006).
38. Lee BI, Choi KY, Lee KM et al. Is C3435T polymorphism of MDR1 related to inflammatory bowel disease or colorectal cancer in Korean? Korean J. Gastroenterol. 47, 22-29 (2006).
39. Osswald E, Johne A, Laschinski G et al. Association of MDR1 genotypes with susceptibility to colorectal cancer in older non-smokers. Eur. J. Clin. Pharmacol. 63, 9-16 (2007). (Pubitemid 46025468)
40. Humeny A, Rödel F, Rödel C et al. MDR1 single nucleotide polymorphism C3435T in normal colorectal tissue and colorectal carcinomas detected by MALDI-TOF mass spectrometry. Anticancer Res. 23(3B), 2735-2740 (2003). (Pubitemid 36897152)
41. Petrova DT, Nedeva P, Maslyankov S et al. No association between MDR1 (ABCB1) 2677G T and 3435C T polymorphism and sporadic colorectal cancer among Bulgarian patients. J. Cancer Res. Clin. Oncol. 134, 317-322 (2008). (Pubitemid 351170052)
42. Samanian S, Mahjoubi F, Mahjoubi B et al. MDR1 gene polymorphisms: possible association with its expression and clinicopathology characteristics in colorectal cancer patients. Asian Pac. J. Cancer Prev. 12(11), 3141-3145 (2011).
43. Potocnik U, Glavac D, Dean M. Common germline MDR1/ABCB1 functional polymorphisms and haplotypes modify susceptibility to colorectal cancers with high microsatellite instability. Cancer Genet. Cytogenet. 183, 28-34 (2008). (Pubitemid 351636126)
44. Kerb R. Implications of genetic polymorphisms in drug transporters for pharmacotherapy. Cancer Lett. 234(1), 4-33 (2006). (Pubitemid 43343938)
45. Robert J, Morvan VL, Smith D et al. Predicting drug response and toxicity based on gene polymorphisms. Crit. Rev. Oncol. Hematol. 54(3), 171-196 (2005). (Pubitemid 40693684)
46. Balcerczak E, Panczyk M, Piaskowski S, Pasz-Walczak G, Saagacka A, Mirowski M. ABCB1/MDR1 gene polymorphisms as a prognostic factor in colorectal cancer. Int. J. Colorectal Dis. 25, 1167-1176 (2010).
47. Potonik U, Ferkolj I, Glavac D et al. polymorphsims in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis. Genes Immun. 5, 530-539 (2004). (Pubitemid 39529969)
48. Panczyk M, Balcerczak E, Piaskowski S et al. ABCB1 gene polymorphisms and haplotype analysis in colorectal cancer. Int. J. Colorectal Dis. 24, 895-905 (2009).