Evidence for a better nodal staging system for melanoma: The clinical relevance of metastatic disease confined to the sentinel lymph nodes

Annals of Surgical Oncology

Volumn 20, Issue 2, 2013, Pages 668-674

  Reintgen, Michael ^a,b   Murray, Lauren ^a,b   Akman, Kurt ^a,b   Giuliano, Rosemary ^a,b   Lozicki, Alyson ^a,b   Shivers, Steve ^a,b   Reintgen, Douglas ^a,b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b FLORIDA HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CANCER STAGING; DISEASE FREE SURVIVAL; FEMALE; HUMAN; LYMPH NODE DISSECTION; MAJOR CLINICAL STUDY; MALE; MELANOMA; OVERALL SURVIVAL; SENTINEL LYMPH NODE METASTASIS;

FEMALE; FOLLOW-UP STUDIES; HUMANS; LYMPH NODE EXCISION; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MELANOMA; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; SENTINEL LYMPH NODE BIOPSY; SURVIVAL RATE;

EID: 84878855194     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-012-2652-4     Document Type: Article

References (15)

1. Ross MI, Reintgen DS, Balch CM. Selective lymphadenectomy: the emerging role of lymphatic mapping and sentinel node biopsy in the management of early stage melanoma. Semin Surg Oncol. 1993;9:219-23.
2. Reintgen DS, Cruse CW, Wells K, Berman C, Fenske N, Glass F, et al. The orderly progression of melanoma nodal metastases. Ann Surg. 1994;220:759-67.
3. Miliotes G, Albertini J, Berman C, Messina J, Glass F, Cruse CW, et al. The tumor biology of melanoma nodal metastases. Am Surg. 1996;62:81-8.
4. American Joint Committee on Cancer Staging Manuel, 7th ed. New York: Springer; 2011.
5. Balch C, Gershenwald JE, Soong S-J, Thompson J, Byrd D, Cascinelli N, et al. Multivariate analysis of prognostic factors among 2313 patients with stage III melanoma: Comparison of nodal micrometastases versus macrometastases. J Clin Oncol. 2010;28:2452-9.
6. Cox C, DuPont E, Furman B, Stowell N, Clark J, Ebert M, et al. The clinical relevance of positive sentinel nodes only vs. positive nonsentinel lymph nodes in breast cancer. Am J Surg. 2002;186:333-6.
7. Jakub J, Bryant K, Huebner M, Hoskin T, Boughey J, Reynolds C, et al. The number of axillary lymph nodes involved with metastatic breast cancer does not affect outcome as long as all the disease is confined to the sentinel lymph nodes. Ann Surg Oncol. 2011;18:86-93.
8. Cascinelli N, Bombardieri E, Bufalino R, Camerini T, Carbone A, Clemente C, et al. Sentinel and nonsentinel node status in Stage IB and II melanoma patients: two-step prognostic indicators for survival. J Clin Oncol. 2006;24:4464-71.
9. Roka F, Mastan P, Binder M, Okamoto I, Mittlboeck M, Horvat R, et al. Prediction of non-sentinel node status and outcome in sentinel node positive melanoma patients. Eur J Surg Oncol. 2008;34:82-8.
10. Ariyan C, Brady MS, Gonen M, Busam K, Coit D. Positive nonsentinel node status predicts mortality in patients with cutaneous melanoma. Ann Surg Oncol. 2009;16:186-90.
11. Ghaferi AA, Wong SL, Johnson TM, Lowe L, Chang AE, Cimmino VM, et al. Prognostic significance of a positive non-sentinel lymph node in cutaneous melanoma. Ann Surg Oncol. 2009;16:2974-84.
12. Brown RE, Ross M, Edwards MJ, Noyes D, Reintgen DS, Hagendoorn L, et al. The prognostic significance of nonsentinel lymph node metastases in melanoma. Ann Surg Oncol. 2010;17:3330-5.
13. Dadras SS, Lange-Asschenfeldt B, Velsco P, Nguyen L, Vora A, Muzikansky A, et al. Tumor lymphangiogenesis predicts melanoma metastases to sentinel lymph nodes. Mod Pathol. 2005;18:1232-42.
14. Cochran AJ, Huang RR, Lee J, Itakura E, Leong SP, Essner R. Tumour-induced immune modulation of sentinel lymph nodes. Nat Rev Immunol. 2006;6:659-70.
15. McMasters K, Wong SL, Edwards M, Cho C, Ross M, Noyes D, et al. Frequency of nonsentinel lymph node metastases in melanoma. Ann Surg Oncol. 2002;9:137-41.