Is complete lymph node dissection after a positive sentinel lymph node biopsy for cutaneous melanoma always necessary? A meta-analysis

European Journal of Surgical Oncology

Volumn 39, Issue 7, 2013, Pages 669-680

  Nagaraja, V ^a   Eslick, G D ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Cutaneous melanoma; Lymph node dissection; Meta analysis; Sentinel lymph node biopsy

Indexed keywords

CUTANEOUS MELANOMA; HUMAN; LYMPH NODE DISSECTION; METASTASIS; NEUROLOGIC DISEASE; NEUROTROPISM; NON SINTINEL NODE METASTASIS; PRIORITY JOURNAL; REVIEW; SATELLITOSIS; SENTINEL LYMPH NODE BIOPSY; SYSTEMATIC REVIEW; TUMOR INVASION; ULCER;

ADULT; AGED; CAUSE OF DEATH; CONFIDENCE INTERVALS; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; LYMPH NODE EXCISION; LYMPHATIC METASTASIS; MALE; MELANOMA; MIDDLE AGED; NEOPLASM STAGING; ODDS RATIO; PREDICTIVE VALUE OF TESTS; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SENTINEL LYMPH NODE BIOPSY; SKIN NEOPLASMS; SURVIVAL ANALYSIS;

EID: 84878839932     PISSN: 07487983     EISSN: 15322157     Source Type: Journal    
DOI: 10.1016/j.ejso.2013.02.022     Document Type: Review

References (94)

1. C.M. Balch, A.C. Buzaid, and S.J. Soong Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma J Clin Oncol 19 16 2001 3635 3648
2. D.L. Morton, D.R. Wen, and J.H. Wong Technical details of intraoperative lymphatic mapping for early stage melanoma Arch Surg 127 4 1992 392 399
3. J.F. Thompson The Sydney Melanoma Unit experience of sentinel lymphadenectomy for melanoma Ann Surg Oncol 8 9 Suppl. 2001 44S 47S
4. J.F. Thompson, J.R. Stretch, R.F. Uren, V.S. Ka, and R.A. Scolyer Sentinel node biopsy for melanoma: where have we been and where are we going? Ann Surg Oncol 11 3 Suppl. 2004 147S 151S
5. D.L. Morton, J.F. Thompson, and R. Essner Validation of the accuracy of intraoperative lymphatic mapping and sentinel lymphadenectomy for early-stage melanoma: a multicenter trial. Multicenter Selective Lymphadenectomy Trial Group Ann Surg 230 4 1999 453 463
6. A. Testori, G.L. De Salvo, and M.C. Montesco Clinical considerations on sentinel node biopsy in melanoma from an Italian multicentric study on 1,313 patients (SOLISM-IMI) Ann Surg Oncol 16 7 2009 2018 2027
7. C.M. Balch Prognostic factors analysis of 17,600 melanoma patients: validation of the American Joint Committee on Cancer melanoma staging system J Clin Oncol 19 16 2001 3622 3634
8. C.M. Balch, D.L. Morton, and J.E. Gershenwald Sentinel node biopsy and standard of care for melanoma J Am Acad Dermatol 60 5 2009 872 875
9. J.H. Lee, R. Essner, H. Torisu-Itakura, L. Wanek, H. Wang, and D.L. Morton Factors predictive of tumor-positive nonsentinel lymph nodes after tumor-positive sentinel lymph node dissection for melanoma J Clin Oncol 22 18 2004 3677 3684
10. N. Cascinelli, E. Bombardieri, and R. Bufalino Sentinel and nonsentinel node status in stage IB and II melanoma patients: two-step prognostic indicators of survival J Clin Oncol 24 27 2006 4464 4471
11. R. Murali, C. Desilva, J.F. Thompson, and R.A. Scolyer Non-Sentinel Node Risk Score (N-SNORE): a scoring system for accurately stratifying risk of non-sentinel node positivity in patients with cutaneous melanoma with positive sentinel lymph nodes J Clin Oncol 28 29 2010 4441 4449
12. I.M. van der Ploeg, B.B. Kroon, N. Antonini, R.A. Valdes Olmos, and O.E. Nieweg Comparison of three micromorphometric pathology classifications of melanoma metastases in the sentinel node Ann Surg 250 2 2009 301 304
13. A.P. van der Ploeg, A.C. van Akkooi, and P. Rutkowski Prognosis in patients with sentinel node-positive melanoma is accurately defined by the combined Rotterdam tumor load and Dewar topography criteria J Clin Oncol 29 16 2011 2206 2214
14. C.R. Rossi, G.L. De Salvo, and E. Bonandini Factors predictive of nonsentinel lymph node involvement and clinical outcome in melanoma patients with metastatic sentinel lymph node Ann Surg Oncol 15 4 2008 1202 1210
15. R. Younan, A. Bougrine, and K. Watters Validation study of the s classification for melanoma patients with positive sentinel nodes: the Montreal experience Ann Surg Oncol 17 5 2010 1414 1421
16. A.M. Fink, F. Weihsengruber, and B. Spangl S-classification of sentinel lymph node biopsy predicts the results of complete regional lymph node dissection Melanoma Res 15 4 2005 267 271
17. A.M. Fink, F. Weihsengruber, and N. Duschek Value of micromorphometric criteria of sentinel lymph node metastases in predicting further nonsentinel lymph node metastases in patients with melanoma Melanoma Res 21 2 2011 139 143
18. R. Franco, M. Cantile, and S. Scala Histomorphologic parameters and CXCR4 mRNA and protein expression in sentinel node melanoma metastasis are correlated to clinical outcome Cancer Biol Ther 9 6 2010 423 429
19. K. Namikawa, N. Yamazaki, and Y. Nakai Prediction of additional lymph node positivity and clinical outcome of micrometastases in sentinel lymph nodes in cutaneous melanoma: a multi-institutional study of 450 patients in Japan J Dermatol 39 2 2012 130 137
20. A.C. van Akkooi, J.H. de Wilt, and C. Verhoef Clinical relevance of melanoma micrometastases (<0.1 mm) in sentinel nodes: are these nodes to be considered negative? Ann Oncol 17 10 2006 1578 1585
21. N.W. Pearlman, M.D. McCarter, and M. Frank Size of sentinel node metastases predicts other nodal disease and survival in malignant melanoma Am J Surg 192 6 2006 878 881
22. D.L. Morton, J.F. Thompson, and A.J. Cochran Sentinel-node biopsy or nodal observation in melanoma N Engl J Med 355 13 2006 1307 1317
23. H. Starz Sentinel lymphonodectomy and s-classification: a successful strategy for better prediction and improvement of outcome of melanoma Ann Surg Oncol 11 3 Suppl. 2004 162S 168S
24. D.J. Dewar, B. Newell, M.A. Green, A.P. Topping, B.W. Powell, and M.G. Cook The microanatomic location of metastatic melanoma in sentinel lymph nodes predicts nonsentinel lymph node involvement J Clin Oncol 22 16 2004 3345 3349
25. W.R. Wrightson Complications associated with sentinel lymph node biopsy for melanoma Ann Surg Oncol 10 6 2003 676 680
26. G. Mehra, W.J. Martin, and K. Dowlatshani Sentinel lymph node biopsy lowers the rate of lymphedema when compared with standard axillary lymph node dissection/discussion Am Surg 69 3 2003 209 211 [discussion 12]
27. L.J.A.J.A. Strobbe Positive iliac and obturator nodes in melanoma: survival and prognostic factors Ann Surg Oncol 6 3 1999 255 262
28. M.P. Schijven, A.J. Vingerhoets, and H.J. Rutten Comparison of morbidity between axillary lymph node dissection and sentinel node biopsy Eur J Surg Oncol 29 4 2003 341 350
29. D. Moher, A. Liberati, J. Tetzlaff, and D.G. Altman Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement J Clin Epidemiol 62 10 2009 1006 1012
30. C.K. Chu, K.A. Delman, G.W. Carlson, A.C. Hestley, and D.R. Murray Inguinopelvic lymphadenectomy following positive inguinal sentinel lymph node biopsy in melanoma: true frequency of synchronous pelvic metastases Ann Surg Oncol 18 12 2011 3309 3315
31. I.M. van der Ploeg, B.B. Kroon, N. Antonini, R.A. Valdes Olmos, and O.E. Nieweg Is completion lymph node dissection needed in case of minimal melanoma metastasis in the sentinel node? Ann Surg 249 6 2009 1003 1007
32. P. Rutkowski, Z.I. Nowecki, and Z. Zurawski In transit/local recurrences in melanoma patients after sentinel node biopsy and therapeutic lymph node dissection Eur J Cancer 42 2 2006 159 164
33. V.A. Smith, J.E. Cunningham, and E.J. Lentsch Completion node dissection in patients with sentinel node-positive melanoma of the head and neck Otolaryngol Head Neck Surg 146 4 2012 591 599
34. R. Essner, R. Scheri, M. Kavanagh, H. Torisu-Itakura, L.A. Wanek, and D.L. Morton Surgical management of the groin lymph nodes in melanoma in the era of sentinel lymph node dissection Arch Surg 141 9 2006 877 882
35. K.Y. Bilimoria, C.M. Balch, and D.J. Bentrem Complete lymph node dissection for sentinel node-positive melanoma: assessment of practice patterns in the United States Ann Surg Oncol 15 6 2008 1566 1576
36. G.I. Salti, and T.K. Das Gupta Predicting residual lymph node basin disease in melanoma patients with sentinel lymph node metastases Am J Surg 186 2 2003 98 101
37. J.M. Ranieri, J.D. Wagner, and R. Azuaje Prognostic importance of lymph node tumor burden in melanoma patients staged by sentinel node biopsy Ann Surg Oncol 9 10 2002 975 981
38. U. Leiter, P.G. Buettner, and K. Bohnenberger Sentinel lymph node dissection in primary melanoma reduces subsequent regional lymph node metastasis as well as distant metastasis after nodal involvement Ann Surg Oncol 17 1 2010 129 137
39. E. Livingstone, C. Windemuth-Kieselbach, and T.K. Eigentler A first prospective population-based analysis investigating the actual practice of melanoma diagnosis, treatment and follow-up Eur J Cancer 47 13 2011 1977 1989
40. F.F. Haddad, A. Stall, and J. Messina The progression of melanoma nodal metastasis is dependent on tumor thickness of the primary lesion Ann Surg Oncol 6 2 1999 144 149
41. K.E. Wells, D.P. Rapaport, and C.W. Cruse Sentinel lymph node biopsy in melanoma of the head and neck Plast Reconstr Surg 100 3 1997 591 594
42. M. Gipponi, N. Solari, and R. Lionetto The prognostic role of the sentinel lymph node in clinically node-negative patients with cutaneous melanoma: experience of the Genoa group Eur J Surg Oncol 31 10 2005 1191 1197
43. R. DerSimonian, and N. Laird Meta-analysis in clinical trials Control Clin Trials 7 3 1986 177 188
44. J.P. Higgins, S.G. Thompson, J.J. Deeks, and D.G. Altman Measuring inconsistency in meta-analyses BMJ 327 7414 2003 557 560
45. M. Egger, G.D. Smith, M. Schneider, and C. Minder Bias in meta-analysis detected by a simple, graphical test BMJ 315 7109 1997 629 634
46. R. Orwin A fail-safe N for effect size in meta-analysis J Educ Stat 8 1983 157 159
47. J.E. Gershenwald, R.H. Andtbacka, and V.G. Prieto Microscopic tumor burden in sentinel lymph nodes predicts synchronous nonsentinel lymph node involvement in patients with melanoma J Clin Oncol 26 26 2008 4296 4303
48. T. Francischetto, N. Spector, and J.F. Neto Rezende Influence of sentinel lymph node tumor burden on survival in melanoma Ann Surg Oncol 17 4 2010 1152 1158
49. I. Satzger, B. Volker, A. Meier, A. Kapp, and R. Gutzmer Criteria in sentinel lymph nodes of melanoma patients that predict involvement of nonsentinel lymph nodes Ann Surg Oncol 15 6 2008 1723 1732
50. S. Debarbieux, G. Duru, S. Dalle, O. Beatrix, B. Balme, and L. Thomas Sentinel lymph node biopsy in melanoma: a micromorphometric study relating to prognosis and completion lymph node dissection Br J Dermatol 157 1 2007 58 67
51. M.E. Reeves, R. Delgado, K.J. Busam, M.S. Brady, and D.G. Coit Prediction of nonsentinel lymph node status in melanoma Ann Surg Oncol 10 1 2003 27 31
52. R.A. Scolyer, L.X. Li, and S.W. McCarthy Micromorphometric features of positive sentinel lymph nodes predict involvement of nonsentinel nodes in patients with melanoma Am J Clin Pathol 122 4 2004 532 539
53. R.J. Vuylsteke, P.J. Borgstein, and P.A. van Leeuwen Sentinel lymph node tumor load: an independent predictor of additional lymph node involvement and survival in melanoma Ann Surg Oncol 12 6 2005 440 448
54. A. Govindarajan, D.M. Ghazarian, D.R. McCready, and W.L. Leong Histological features of melanoma sentinel lymph node metastases associated with status of the completion lymphadenectomy and rate of subsequent relapse Ann Surg Oncol 14 2 2007 906 912
55. A.J. Cochran, D.R. Wen, R.R. Huang, H.J. Wang, R. Elashoff, and D.L. Morton Prediction of metastatic melanoma in nonsentinel nodes and clinical outcome based on the primary melanoma and the sentinel node Mod Pathol 17 7 2004 747 755
56. M.S. Sabel, K. Griffith, and V.K. Sondak Predictors of nonsentinel lymph node positivity in patients with a positive sentinel node for melanoma J Am Coll Surg 201 1 2005 37 47
57. M. Wiener, K.M. Acland, and H.M. Shaw Sentinel node positive melanoma patients: prediction and prognostic significance of nonsentinel node metastases and development of a survival tree model Ann Surg Oncol 17 8 2010 1995 2005
58. A. Meier, I. Satzger, B. Volker, A. Kapp, and R. Gutzmer Comparison of classification systems in melanoma sentinel lymph nodes - an analysis of 697 patients from a single center Cancer 116 13 2010 3178 3188
59. I. Satzger, B. Volker, M. Al Ghazal, A. Meier, A. Kapp, and R. Gutzmer Prognostic significance of histopathological parameters in sentinel nodes of melanoma patients Histopathology 50 6 2007 764 772
60. R.P. Scheri, R. Essner, R.R. Turner, X. Ye, and D.L. Morton Isolated tumor cells in the sentinel node affect long-term prognosis of patients with melanoma Ann Surg Oncol 14 10 2007 2861 2866
61. F. Roka, P. Mastan, and M. Binder Prediction of non-sentinel node status and outcome in sentinel node-positive melanoma patients Eur J Surg Oncol 34 1 2008 82 88
62. A. Cadili, G. McKinnon, and F. Wright Validation of a scoring system to predict non-sentinel lymph node metastasis in melanoma J Surg Oncol 101 3 2010 191 194
63. A. Cadili, M. Smylie, J. Danyluk, and K. Dabbs Prediction of nonsentinel lymph node metastasis in malignant melanoma J Surg Res 154 2 2009 324 329
64. D.L. Morton, D.S. Hoon, and A.J. Cochran Lymphatic mapping and sentinel lymphadenectomy for early-stage melanoma: therapeutic utility and implications of nodal microanatomy and molecular staging for improving the accuracy of detection of nodal micrometastases Ann Surg 238 4 2003 538 549
65. L. Kretschmer, R. Hilgers, and M. Mohrle Patients with lymphatic metastasis of cutaneous malignant melanoma benefit from sentinel lymphonodectomy and early excision of their nodal disease Eur J Cancer 40 2 2004 212 218
66. A.C. van Akkooi, M.G. Bouwhuis, J.H. de Wilt, M. Kliffen, P.I. Schmitz, and A.M. Eggermont Multivariable analysis comparing outcome after sentinel node biopsy or therapeutic lymph node dissection in patients with melanoma Br J Surg 94 10 2007 1293 1299
67. Z.I. Nowecki, P. Rutkowski, and W. Michej The survival benefit to patients with positive sentinel node melanoma after completion lymph node dissection may be limited to the subgroup with a primary lesion Breslow thickness greater than 1.0 and less than or equal to 4 mm (pT2-pT3) Ann Surg Oncol 15 8 2008 2223 2234
68. M.B. Faries, J.F. Thompson, and A. Cochran The impact on morbidity and length of stay of early versus delayed complete lymphadenectomy in melanoma: results of the Multicenter Selective Lymphadenectomy Trial (I) Ann Surg Oncol 17 12 2010 3324 3329
69. S. Pasquali, S. Mocellin, and L.G. Campana Early (sentinel lymph node biopsy-guided) versus delayed lymphadenectomy in melanoma patients with lymph node metastases: personal experience and literature meta-analysis Cancer 116 5 2010 1201 1209
70. R. Murali, A.J. Cochran, and M.G. Cook Interobserver reproducibility of histologic parameters of melanoma deposits in sentinel lymph nodes: implications for management of patients with melanoma Cancer 115 21 2009 5026 5037
71. T. Bogenrieder, M.R. van Dijk, and W.A. Blokx No non-sentinel node involvement in melanoma patients with limited Breslow thickness and low sentinel node tumour load Histopathology 59 2 2011 318 326
72. J.D. Wagner, D. Davidson, and J.J. Coleman 3rd Lymph node tumor volumes in patients undergoing sentinel lymph node biopsy for cutaneous melanoma Ann Surg Oncol 6 4 1999 398 404
73. E. Joseph, A. Brobeil, and F. Glass Results of complete lymph node dissection in 83 melanoma patients with positive sentinel nodes Ann Surg Oncol 5 2 1998 119 125
74. C. Kunte, T. Geimer, and J. Baumert Analysis of predictive factors for the outcome of complete lymph node dissection in melanoma patients with metastatic sentinel lymph nodes J Am Acad Dermatol 64 4 2011 655 662
75. K.M. McMasters, S.L. Wong, and M.J. Edwards Frequency of nonsentinel lymph node metastasis in melanoma Ann Surg Oncol 9 2 2002 137 141
76. Z.I. Nowecki, P. Rutkowski, A. Nasierowska-Guttmejer, and W. Ruka Sentinel lymph node biopsy in melanoma patients with clinically negative regional lymph nodes - one institution's experience Melanoma Res 13 1 2003 35 43
77. L.L. Pu, K.E. Wells, C.W. Cruse, A.R. Shons, and D.S. Reintgen Prevalence of additional positive lymph nodes in complete lymphadenectomy specimens after positive sentinel lymphadenectomy findings for early-stage melanoma of the head and neck Plast Reconstr Surg 112 1 2003 43 49
78. H. Starz, B.R. Balda, K.U. Kramer, H. Buchels, and H. Wang A micromorphometry-based concept for routine classification of sentinel lymph node metastases and its clinical relevance for patients with melanoma Cancer 91 11 2001 2110 2121
79. G.W. Carlson, D.R. Murray, R.H. Lyles, C.A. Staley, A. Hestley, and C. Cohen The amount of metastatic melanoma in a sentinel lymph node: does it have prognostic significance? Ann Surg Oncol 10 5 2003 575 581
80. P. Quaglino, S. Ribero, and S. Osella-Abate Clinico-pathologic features of primary melanoma and sentinel lymph node predictive for non-sentinel lymph node involvement and overall survival in melanoma patients: a single centre observational cohort study Surg Oncol 20 4 2011 259 264
81. A. Cadili, R.A. Scolyer, P.T. Brown, K. Dabbs, and J.F. Thompson Total sentinel lymph node tumor size predicts nonsentinel node metastasis and survival in patients with melanoma Ann Surg Oncol 17 11 2010 3015 3020
82. T.L. Frankel, K.A. Griffith, and L. Lowe Do micromorphometric features of metastatic deposits within sentinel nodes predict nonsentinel lymph node involvement in melanoma? Ann Surg Oncol 15 9 2008 2403 2411
83. M. Santinami, A. Carbone, and F. Crippa Radical dissection after positive groin sentinel biopsy in melanoma patients: rate of further positive nodes Melanoma Res 19 2 2009 112 118
84. C. Ariyan, M.S. Brady, M. Gonen, K. Busam, and D. Coit Positive nonsentinel node status predicts mortality in patients with cutaneous melanoma Ann Surg Oncol 16 1 2009 186 190
85. N. Elias, K.K. Tanabe, and A.J. Sober Is completion lymphadenectomy after a positive sentinel lymph node biopsy for cutaneous melanoma always necessary? Arch Surg 139 4 2004 400 404
86. A.A. Ghaferi, S.L. Wong, and T.M. Johnson Prognostic significance of a positive nonsentinel lymph node in cutaneous melanoma Ann Surg Oncol 16 11 2009 2978 2984
87. M.H. Denis, E. Dudrap, P. Courville, I. Auquit-Auckbur, P. Joly, and P.Y. Milliez Influence of the size and the localization of metastases in melanoma sentinel lymph nodes on the results of lymphadenectomy Ann Chir Plast Esthet 52 1 2007 28 34
88. N. Glumac, M. Hocevar, V. Zadnik, and M. Snoj Sentinel lymph node micrometastasis may predict non-sentinel involvement in cutaneous melanoma patients J Surg Oncol 98 1 2008 46 48
89. M.M. Guggenheim, U. Hug, and F.J. Jung Morbidity and recurrence after completion lymph node dissection following sentinel lymph node biopsy in cutaneous malignant melanoma Ann Surg 247 4 2008 687 693
90. A.J. Page, G.W. Carlson, K.A. Delman, D. Murray, A. Hestley, and C. Cohen Prediction of nonsentinel lymph node involvement in patients with a positive sentinel lymph node in malignant melanoma Am Surg 73 7 2007 674 678
91. A.C. van Akkooi, Z.I. Nowecki, and C. Voit Sentinel node tumor burden according to the Rotterdam criteria is the most important prognostic factor for survival in melanoma patients: a multicenter study in 388 patients with positive sentinel nodes Ann Surg 248 6 2008 949 955
92. J.D. Wagner, J. Ranieri, and D.Z. Evdokimow Patterns of initial recurrence and prognosis after sentinel lymph node biopsy and selective lymphadenectomy for melanoma Plast Reconstr Surg 112 2 2003 486 497
93. J.D. Wagner, H.M. Park, J.J. Coleman 3rd, C. Love, and J.T. Hayes Cervical sentinel lymph node biopsy for melanomas of the head and neck and upper thorax Arch Otolaryngol Head Neck Surg 126 3 2000 313 321
94. J.D. Wagner, M.S. Gordon, and T.Y. Chuang Predicting sentinel and residual lymph node basin disease after sentinel lymph node biopsy for melanoma Cancer 89 2 2000 453 462