Neurofascin 186 specific autoantibodies induce axonal injury and exacerbate disease severity in experimental autoimmune encephalomyelitis

Experimental Neurology

Volumn 247, Issue , 2013, Pages 259-266

  Lindner, Maren ^a   Ng, Judy King Man ^b   Hochmeister, Sonja ^c   Meinl, Edgar ^b   Linington, Christopher ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF MUNICH   (Germany)

^c MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

EAE; Multiple sclerosis; Neurofascin; Pathogenic antibody

Indexed keywords

AUTOANTIBODY; CELL ADHESION MOLECULE; NEUROFASCIN 155; NEUROFASCIN 186; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; AXONAL INJURY; CELL LINE; CONTROLLED STUDY; CROSS REACTION; DARK AGOUTI RAT; DISEASE EXACERBATION; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GENETIC TRANSFECTION; IMMUNIZATION; IMMUNOHISTOLOGY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; T LYMPHOCYTE;

EAE; MULTIPLE SCLEROSIS; NEUROFASCIN; PATHOGENIC ANTIBODY;

ADOPTIVE TRANSFER; ANIMALS; AUTOANTIBODIES; AXONS; CELL ADHESION MOLECULES; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMANS; LYMPHOCYTE ACTIVATION; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; NERVE GROWTH FACTORS; PROTEIN ISOFORMS; RATS; STATISTICS, NONPARAMETRIC;

EID: 84878828001     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.05.005     Document Type: Article

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