Vaccine administration and the development of immune thrombocytopenic purpura in children

Human Vaccines and Immunotherapeutics

Volumn 9, Issue 5, 2013, Pages 1158-1162

  Cecinati, Valerio ^a   Principi, Nicola ^b   Brescia, Letizia ^c   Giordano, Paola ^d   Esposito, Susanna ^b  

^a SPIRITO SANTO HOSPITAL   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^d UNIVERSITY OF BARI   (Italy)

Author keywords

Adverse events; Immune thrombocytopenic purpura; MMR; Platelets; Vaccine; Vaccine safety

Indexed keywords

CHICKENPOX VACCINE; DIPHTHERIA PERTUSSIS TETANUS VACCINE; HEPATITIS A VACCINE; INFLUENZA VACCINE; MEASLES MUMPS RUBELLA VACCINE;

CHILD; CHRONIC DISEASE; DISEASE SEVERITY; DRUG SAFETY; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; INCIDENCE; MEASLES; RECURRENT DISEASE; REVIEW; RISK BENEFIT ANALYSIS; VACCINATION;

ADVERSE EVENTS; IMMUNE THROMBOCYTOPENIC PURPURA; MMR; PLATELETS; VACCINE; VACCINE SAFETY;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; CHRONIC DISEASE; FEMALE; HUMANS; INCIDENCE; INFANT; MALE; MEASLES-MUMPS-RUBELLA VACCINE; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC;

EID: 84878808250     PISSN: 21645515     EISSN: 2164554X     Source Type: Journal    
DOI: 10.4161/hv.23601     Document Type: Review

References (51)

1. Maciosek MV, Coffield AB, Edwards NM, Flottemesch TJ, Goodman MJ, Solberg LI. Priorities among effective clinical preventive services: results of a systematic review and analysis. Am J Prev Med 2006; 31:52-61; PMID:16777543; http://dx.doi.org/10.1016/j.amepre.2006.03.012.
2. Roush SW, Murphy TV; Vaccine-Preventable Disease Table Working Group. Historical comparisons of morbidity and mortality for vaccine-preventable diseases in the United States. JAMA 2007; 298:2155-63; PMID:18000199; http://dx.doi.org/10.1001/jama.298.18.2155.
3. Posfay-Barbe KM, Heininger U, Aebi C, Desgrandchamps D, Vaudaux B, Siegrist CA. How do physicians immunize their own children? Differences among pediatricians and nonpediatricians. Pediatrics 2005; 116:e623-33; PMID:16263976; http://dx.doi.org/10.1542/peds.2005-0885.
4. Blume S. Anti-vaccination movements and their interpretations. Soc Sci Med 2006; 62:628-42; PMID:16039769; http://dx.doi.org/10.1016/j.socs-cimed.2005. 06.020.
5. Healy CM, Pickering LK. How to communicate with vaccine-hesitant parents. Pediatrics 2011; 127(Suppl 1):S127-33; PMID:21502238; http://dx.doi.org/10. 1542/peds.2010-1722S.
6. Rodeghiero F, Stasi R, Gernsheimer T, Michel M, Provan D, Arnold DM, et al. Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group. Blood 2009; 113:2386-93; PMID:19005182; http://dx.doi.org/10. 1182/blood-2008-07-162503.
7. Fujita H. Idiopathic thrombocytopenic purpura following viral infection. Nihon Rinsho 2003; 61:650-4; PMID:12718091.
8. Nugent DJ. Childhood immune thrombocytopenic purpura. Blood Rev 2002; 16:27-9; PMID:11913990; http://dx.doi.org/10.1054/blre.2001.0177.
9. Khorshied MM, El-Ghamrawy MK. DNA methyltransferase 3B (DNMT3B -579G>T) promotor polymorphism and the susceptibility to pediatric immune thrombocytopenic purpura in Egypt. Gene 2012; 511:34-7; PMID:23000068; http://dx.doi.org/10.1016/j.gene.2012.09.024.
10. Sauvé LJ, Scheifele D. Do childhood vaccines cause thrombocytopenia? Paediatr Child Health 2009; 14:31-2; PMID:19436461.
11. Woo EJ, Wise RP, Menschik D, Shadomy SV, Iskander J, Beeler J, et al. Thrombocytopenia after vaccination: case reports to the US Vaccine Adverse Event Reporting System, 1990-2008. Vaccine 2011; 29:1319-23; PMID:21126606; http://dx.doi.org/10.1016/j.vaccine.2010.11.051.
12. Rajantie J, Zeller B, Treutiger I, Rosthöj S; NOPHO ITP working group and five national study groups. Vaccination associated thrombocytopenic purpura in children. Vaccine 2007; 25:1838-40; PMID:17126957; http://dx.doi.org/10.1016/j.vaccine.2006.10.054.
13. O'Leary ST, Glanz JM, McClure DL, Akhtar A, Daley MF, Nakasato C, et al. The risk of immune thrombocytopenic purpura after vaccination in children and adolescents. Pediatrics 2012; 129:248-55; PMID:22232308; http://dx.doi.org/10. 1542/peds.2011-1111.
14. Oski FA, Naiman JL. Effect of live measles vaccine on the platelet count. N Engl J Med 1966; 275:352-6; PMID:5947548; http://dx.doi.org/10.1056/ NEJM196608182750703.
15. Autret E, Jonville-Béra AP, Galy-Eyraud C, Hessel L. Thrombocytopenic purpura after isolated or combined vaccination against measles, mumps and rubella. Therapie 1996; 51:677-80; PMID:9164004.
16. Beeler J, Varricchio F, Wise R. Thrombocytopenia after immunization with measles vaccines: review of the vaccine adverse events reporting system (1990 to 1994). Pediatr Infect Dis J 1996; 15:88-90; PMID:8684885; http://dx.doi.org/10. 1097/00006454-199601000-00020.
17. Black C, Kaye JA, Jick H. MMR vaccine and idiopathic thrombocytopaenic purpura. Br J Clin Pharmacol 2003; 55:107-11; PMID:12534647; http://dx.doi.org/10.1046/j.1365-2125.2003.01790.x.
18. France EK, Glanz J, Xu S, Hambidge S, Yamasaki K, Black SB, et al.; Vaccine Safety Datalink Team. Risk of immune thrombocytopenic purpura after measles-mumps-rubella immunization in children. Pediatrics 2008; 121:e687-92; PMID:18310189; http://dx.doi.org/10.1542/peds.2007-1578.
19. Jonville-Béra AP, Autret E, Galy-Eyraud C, Hessel L. Thrombocytopenic purpura after measles, mumps and rubella vaccination: a retrospective survey by the French regional pharmacovigilance centres and pasteur-mérieux sérums et vaccins. Pediatr Infect Dis J 1996; 15:44-8; PMID:8684875; http://dx.doi.org/10.1097/00006454-199601000-00010.
20. Kiefaber RW. Thrombocytopenic purpura after measles vaccination. N Engl J Med 1981; 305:225; PMID:7195464; http://dx.doi.org/10.1056/NEJM198107233050417.
21. Mantadakis E, Farmaki E, Buchanan GR. Thrombocytopenic purpura after measles-mumps-rubella vaccination: a systematic review of the literature and guidance for management. J Pediatr 2010; 156:623-8; PMID:20097358; http://dx.doi.org/10.1016/j.jpeds.2009.10.015.
22. Miller E, Waight P, Farrington CP, Andrews N, Stowe J, Taylor B. Idiopathic thrombocytopenic purpura and MMR vaccine. Arch Dis Child 2001; 84:227-9; PMID:11207170; http://dx.doi.org/10.1136/adc.84.3.227.
23. Nieminen U, Peltola H, Syrjälä MT, Mäkipernaa A, Kekomäki R. Acute thrombocytopenic purpura following measles, mumps and rubella vaccination. A report on 23 patients. Acta Paediatr 1993; 82:267-70; PMID:8495082; http://dx.doi.org/10.1111/j.1651-2227.1993.tb12657.x.
24. Demicheli V, Rivetti A, Debalini MG, Di Pietrantonj C. Vaccines for measles, mumps and rubella in children. Cochrane Database Syst Rev 2012; 2:CD004407; PMID:22336803.
25. Okazaki N, Takeguchi M, Sonoda K, Handa Y, Kakiuchi T, Miyahara H, et al. Detection of platelet-binding anti-measles and anti-rubella virus IgG antibodies in infants with vaccine-induced thrombocytopenic purpura. Vaccine 2011; 29:4878-80; PMID:21539881; http://dx.doi.org/10.1016/j.vaccine.2011.04. 036.
26. Ozsoylu S, Kanra G, Savaş G. Thrombocytopenic purpura related to rubella infection. Pediatrics 1978; 62:567-9; PMID:568768.
27. Gold E. Almost extinct diseases: measles, mumps, rubella, and pertussis. Pediatr Rev 1996; 17:120-7; PMID:8637818; http://dx.doi.org/10.1542/pir.17-4- 120.
28. Andrews N, Stowe J, Miller E, Svanström H, Johansen K, Bonhoeffer J, et al.; VAESCO consortium. A collaborative approach to investigating the risk of thrombocytopenic purpura after measles-mumps-rubella vaccination in England and Denmark. Vaccine 2012; 30:3042-6; PMID:21699947; http://dx.doi.org/10.1016/ j.vaccine.2011.06.009.
29. Jadavji T, Scheifele D, Halperin S; Canadian Paediatric Society/Health Cananda Immunization Monitoring Program. Thrombocytopenia after immunization of Canadian children, 1992 to 2001. Pediatr Infect Dis J 2003; 22:119-22; PMID:12586974; http://dx.doi.org/10.1097/01.inf.0000048961.08486.d1.
30. Vlacha V, Forman EN, Miron D, Peter G. Recurrent thrombocytopenic purpura after repeated measles-mumps-rubella vaccination. Pediatrics 1996; 97:738-9; PMID:8628619.
31. Drachtman RA, Murphy S, Ettinger LJ. Exacerbation of chronic idiopathic thrombocytopenic purpura following measles-mumps-rubella immunization. Arch Pediatr Adolesc Med 1994; 148:326-7; PMID:8130872; http://dx.doi.org/10.1001/ archpedi.1994.02170030096023.
32. Bibby AC, Farrell A, Cummins M, Erlewyn-Lajeunesse M. Is MMR immunisation safe in chronic Idiopathic thrombocytopenic purpura? Arch Dis Child 2008; 93:354-5; PMID:18356391; http://dx.doi.org/10.1136/adc.2007.132340.
33. British Committee for Standards in Haematology General Haematology Task Force. Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy. Br J Haematol 2003; 120:574-96; PMID:12588344; http://dx.doi.org/10.1046/j.1365-2141.2003. 04131.x.
34. Poullin P, Gabriel B. Thrombocytopenic purpura after recombinant hepatitis B vaccine. Lancet 1994; 344:1293; PMID:7967998; http://dx.doi.org/10. 1016/S0140-6736(94)90777-3.
35. Nuevo H, Nascimento-Carvalho CM, Athayde-Oliveira CP, Lyra I, Moreira LM. Thrombocytopenic purpura after hepatitis B vaccine: case report and review of the literature. Pediatr Infect Dis J 2004; 23:183-4; PMID:14872193; http://dx.doi.org/10.1097/01.inf.0000109846.59440.a1.
36. Meyboom RH, Fucik H, Edwards IR. Thrombocytopenia reported in association with hepatitis B and A vaccines. Lancet 1995; 345:1638; PMID:7632294; http://dx.doi.org/10.1016/S0140-6736(95)90143-4.
37. Hsieh YL, Lin LH. Thrombocytopenic purpura following vaccination in early childhood: experience of a medical center in the past 2 decades. J Chin Med Assoc 2010; 73:634-7; PMID:21145511; http://dx.doi.org/10.1016/S1726-4901(10) 70138-6.
38. Rivest P, Bédard L, Valiquette L, Mills E, Lebel MH, Lavoie G, et al. Severe complications associated with varicella: Province of Quebec, April 1994 to March 1996. Can J Infect Dis 2001; 12:21-6; PMID:18159313.
39. Tishler M, Levy O, Amit-Vazina M. Immune thrombocytopenic purpura following influenza vaccination. Isr Med Assoc J 2006; 8:322-3; PMID:16805230.
40. Kelton JG. Vaccination-Associated relapse of immune thrombocytopenia. JAMA 1981; 245:369-70; PMID:6969806; http://dx.doi.org/10.1001/jama.1981. 03310290037020.
41. Granier H, Nicolas X, Laborde JP, Talarmin F. Severe autoimmune thrombopenia following anti-influenza vaccination. Presse Med 2003; 32:1223-4; PMID:14506462.
42. Casoli P, Tumiati B. Acute idiopathic thrombocytopenic purpura after anti-influenza vaccination. Medicina (Firenze) 1989; 9:417-8; PMID:2634230.
43. Ikegame K, Kaida K, Fujioka T, Kawakami M, Hasei H, Inoue T, et al. Idiopathic thrombocytopenic purpura after influenza vaccination in a bone marrow transplantation recipient. Bone Marrow Transplant 2006; 38:323-4, author reply 324-5; PMID:16883314; http://dx.doi.org/10.1038/sj.bmt.1705442.
44. Mamori S, Amano K, Kijima H, Takagi I, Tajiri H. Thrombocytopenic purpura after the administration of an influenza vaccine in a patient with autoimmune liver disease. Digestion 2008; 77:159-60; PMID:18577855; http://dx.doi.org/10. 1159/000140977.
45. Garbe E, Andersohn F, Bronder E, Salama A, Klimpel A, Thomae M, et al. Drug-induced immune thrombocytopaenia: results from the Berlin Case-Control Surveillance Study. Eur J Clin Pharmacol 2012; 68:821-32; PMID:22187020; http://dx.doi.org/10.1007/s00228-011-1184-3.
46. Mantadakis E, Farmaki E, Thomaidis S, Tsalkidis A, Chatzimichael A. A case of immune thrombocytopenic purpura after influenza vaccination: consequence or coincidence? J Pediatr Hematol Oncol 2010; 32:e227-9; PMID:20539239; http://dx.doi.org/10.1097/MPH.0b013e3181e33fe0.
47. Moulis G, Sommet A, Sailler L, Lapeyre-Mestre M, Montastruc JL; French Association Of Regional Pharmacovigilance Centers. Drug-induced immune thrombocytopenia: a descriptive survey in the French PharmacoVigilance database. Platelets 2012; 23:490-4; PMID:22098130; http://dx.doi.org/10.3109/09537104. 2011.633179.
48. Esposito S, Montinaro V, Groppali E, Tenconi R, Semino M, Principi N. Live attenuated intranasal influenza vaccine. Hum Vaccin Immunother 2012; 8:76-80; PMID:22251995.
49. Jain S, Kamimoto L, Bramley AM, Schmitz AM, Benoit SR, Louie J, et al.; 2009 Pandemic Influenza A (H1N1) Virus Hospitalizations Investigation Team. Hospitalized patients with 2009 H1N1 influenza in the United States, April-June 2009. N Engl J Med 2009; 361:1935-44; PMID:19815859; http://dx.doi.org/10.1056/ NEJMoa0906695.
50. Areechokchai D, Jiraphongsa C, Laosiritaworn Y, Hanshaoworakul W, O'Reilly M; Centers for Disease Control and Prevention (CDC). Investigation of avian influenza (H5N1) outbreak in humans - Thailand, 2004. MMWR Morb Mortal Wkly Rep 2006; 55(Suppl 1):3-6; PMID:16645574.
51. Kaneko H, Ohkawara Y, Nomura K, Horiike S, Taniwaki M. Relapse of idiopathic thrombocytopenic purpura caused by influenza A virus infection: a case report. J Infect Chemother 2004; 10:364-6; PMID:15614463; http://dx.doi.org/10.1007/s10156-004-0343-1.