Preoperative platelet count in predicting lymph node metastasis and prognosis in patients with non-small cell lung cancer

Neoplasma

Volumn 60, Issue 2, 2013, Pages 203-208

  Liu, H B ^a   Gu, X L ^a   Ma, X Q ^a   Lv, T F ^a   Wu, Y ^b   Xiao, Y Y ^a   Yuan, D M ^a   Li, Y F ^a   Song, Y ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b Jiangsu Province Geriatric Hospital   (China)

Author keywords

Lymph nodes; Metastasis; Non small cell lung cancer; Preoperative platelet count; Prognosis

Indexed keywords

ADULT; AGED; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; HUMAN; LUNG NON SMALL CELL CANCER; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; OVERALL SURVIVAL; PREOPERATIVE EVALUATION; RECEIVER OPERATING CHARACTERISTIC; RISK FACTOR; SENSITIVITY AND SPECIFICITY; THROMBOCYTE COUNT; VERY ELDERLY; ADOLESCENT; BLOOD; LUNG TUMOR; MIDDLE AGED; MORTALITY; PATHOLOGY; PROGNOSIS; PROPORTIONAL HAZARDS MODEL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; FEMALE; HUMANS; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM STAGING; PLATELET COUNT; PROGNOSIS; PROPORTIONAL HAZARDS MODELS;

EID: 84878786517     PISSN: 00282685     EISSN: 13384317     Source Type: Journal    
DOI: 10.4149/neo_2013_027     Document Type: Article

References (30)

1. SIEGEL R, NAISHADHAM D, JEMAL A. Cancer statistics, 2012. CA Cancer J Clin 2012; 62: 10-29. http://dx.doi.org/10.3322/caac.20138
2. MOLINA JR, YANG P, CASSIVI SD, SCHILD SE, ADJEI AA. Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc 2008; 83: 584-594.
3. WAKELEE HA, BERNARDO P, JOHNSON DH, SCHILLER JH. Changes in the natural history of nonsmall cell lung cancer (NSCLC)--comparison of outcomes and characteristics in patients with advanced NSCLC entered in Eastern Cooperative Oncology Group trials before and after 1990. Cancer 2006; 106: 2208-2217. http://dx.doi.org/10.1002/cncr.21869
4. CAO Y, ZHONG W. Tumor-derived lymphangiogenic factors and lymphatic metastasis. Biomed Pharmacother 2007; 61: 534-539. http://dx.doi.org/10.1016/j.biopha.2007.08.009
5. KRZYSTEK-KORPACKA M, DIAKOWSKA D, GAMIAN A, MATUSIEWICZ M. Increase in serum platelet-derived growth factor (PDGF)-BB reflects lymph node involvement in esophageal cancer patients independently from platelet count. Exp Oncol 2011; 33: 140-144.
6. CAO R, BJORNDAHL MA, RELIGA P, CLASPER S, GARVIN S et al. PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis. Cancer Cell 2004; 6: 333-345. http://dx.doi.org/10.1016/j.ccr.2004.08.034
7. HELDIN CH, WESTERMARK B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev 1999; 79: 1283-1316.
8. SOBIN LH GM, WITTEKIND C. TNM classification of malignant tumors (UICC International Union Against Cancer). 7th ed. Oxford: Wiley-Blackwell 2009.
9. SASAKI K, KAWAI K, TSUNO NH, SUNAMI E, KITAYAMA J. Impact of preoperative thrombocytosis on the survival of patients with primary colorectal cancer. World J Surg 2012; 36: 192-200. http://dx.doi.org/10.1007/s00268-011-1329-7
10. LIN MS, HUANG JX, ZHU J, SHEN HZ. Elevation of platelet count in patients with colorectal cancer predicts tendency to metastases and poor prognosis. Hepatogastroenterology 2012; 59: 1687-1690. http://dx.doi.org/10.5754/hge12277
11. GONZALEZ BARCALA FJ, GARCIA PRIM JM, MOLDES RODRIGUEZ M, ALVAREZ FERNANDEZ J, REY REY MJ et al. Platelet count: association with prognosis in lung cancer. Medical oncology 2010; 27: 357-362. http://dx.doi.org/10.1007/s12032-009-9217-9
12. CAKAR B, KARAOGLANOGLU M, SAYICI Y, GONULLU DEMIRAG G, YUCEL I. The prognostic value of thrombocytosis in newly diagnosed lung cancer patients: a retrospective analysis. J BUON 2011; 16: 677-681.
13. SCULIER JP, CHANSKY K, CROWLEY JJ, VAN MEERBEECK J, GOLDSTRAW P. The impact of additional prognostic factors on survival and their relationship with the anatomical extent of disease expressed by the 6th Edition of the TNM Classification of Malignant Tumors and the proposals for the 7th Edition. J Thorac Oncol 2008; 3: 457-466. http://dx.doi.org/10.1097/JTO.0b013e31816de2b8
14. HSU CP, HSIA JY, CHANG GC, CHUANG CY, SHAI SE et al. Surgical-pathologic factors affect long-term outcomes in stage IB (pT2 N0 M0) non-small cell lung cancer: a heterogeneous disease. J Thorac Cardiovasc Surg 2009; 138: 426-433. http://dx.doi.org/10.1016/j.jtcvs.2008.12.035
15. PALOMARES MR, SAYRE JW, SHEKAR KC, LILLINGTON LM, CHLEBOWSKI RT. Gender influence on weight-loss pattern and survival of nonsmall cell lung carcinoma patients. Cancer 1996; 78: 2119-2126. http://dx.doi.org/10.1002/(SICI)1097-0142(19961115)78:10<2119::AIDCNCR12>3.0.CO;2-1
16. ACHEN MG, STACKER SA. Molecular control of lymphatic metastasis. Ann N Y Acad Sci 2008; 1131: 225-234. http://dx.doi.org/10.1196/annals.1413.020
17. ZHANG Z, HELMAN JI, LI LJ. Lymphangiogenesis, lymphatic endothelial cells and lymphatic metastasis in head and neck cancer--a review of mechanisms. Int J Oral Sci 2010; 2: 5-14. http://dx.doi.org/10.4248/IJOS10006
18. THELEN A, JONAS S, BENCKERT C, WEICHERT W, SCHOTT E et al. Tumor-associated lymphangiogenesis correlates with prognosis after resection of human hepatocellular carcinoma. Ann Surg Oncol 2009; 16: 1222-1230. http://dx.doi.org/10.1245/s10434-009-0380-1
19. BRITTO AV, SCHENKA AA, MORAES-SCHENKA NG, ALVARENGA M, SHINZATO JY et al. Immunostaining with D2-40 improves evaluation of lymphovascular invasion, but may not predict sentinel lymph node status in early breast cancer. BMC Cancer 2009; 9: 109. http://dx.doi.org/10.1186/1471-2407-9-109
20. KOUKOURAKIS MI, GIATROMANOLAKI A, SIVRIDIS E, SIMOPOULOS C, GATTER KC et al. LYVE-1 immunohistochemical assessment of lymphangiogenesis in endometrial and lung cancer. J Clin Pathol 2005; 58: 202-206. http://dx.doi.org/10.1136/jcp.2004.019174
21. UHRIN P, ZAUJEC J, BREUSS JM, OLCAYDU D, CHRENEK P et al. Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation. Blood 2010; 115: 3997-4005. http://dx.doi.org/10.1182/blood-2009-04-216069
22. JURASZ P, ALONSO D, CASTRO-BLANCO S, MURAD F, RADOMSKI MW. Generation and role of angiostatin in human platelets. Blood 2003; 102: 3217-3223. http://dx.doi.org/10.1182/blood-2003-02-0378
23. NAKAYA H, KAWASHIRI S, TANAKA A, NOGUCHI N, KATO K et al. Influences of angiogenesis and lymphangiogenesis on cancerous invasion in experimentally induced tongue carcinoma. J Oral Pathol Med 2005; 34: 87-92. http://dx.doi.org/10.1111/j.1600-0714.2004.00279.x
24. SAINTIGNY P, KAMBOUCHNER M, LY M, GOMES N, SAINTE-CATHERINE O et al. Vascular endothelial growth factor-C and its receptor VEGFR-3 in non-small-cell lung cancer: concurrent expression in cancer cells from primary tumour and metastatic lymph node. Lung Cancer 2007; 58: 205-213. http://dx.doi.org/10.1016/j.lungcan.2007.06.021
25. LU CC, CHANG KW, CHOU FC, CHENG CY, LIU CJ. Association of pretreatment thrombocytosis with disease progression and survival in oral squamous cell carcinoma. Oral Oncol 2007; 43: 283-288. http://dx.doi.org/10.1016/j.oraloncology.2006.03.010
26. IWASAKI A, KUWAHARA M, YOSHINAGA Y, SHIRAKUSA T. Basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF) levels, as prognostic indicators in NSCLC. Eur J Cardiothorac Surg 2004; 25: 443-448. http://dx.doi.org/10.1016/j.ejcts.2003.11.031
27. KLERK CP, SMORENBURG SM, OTTEN HM, LENSING AW, PRINS MH et al. The effect of low molecular weight heparin on survival in patients with advanced malignancy. J Clin Oncol 2005; 23: 2130-2135. http://dx.doi.org/10.1200/JCO.2005.03.134
28. LEE AY, RICKLES FR, JULIAN JA, GENT M, BAKER RI et al. Randomized comparison of low molecular weight heparin and coumarin derivatives on the survival of patients with cancer and venous thromboembolism. J Clin Oncol 2005; 23: 2123-2129. http://dx.doi.org/10.1200/JCO.2005.03.133
29. AOE K, HIRAKI A, UEOKA H, KIURA K, TABATA M et al. Thrombocytosis as a useful prognostic indicator in patients with lung cancer. Respiration 2004; 71: 170-173. http://dx.doi.org/10.1159/000076679
30. SHIMADA H, OOHIRA G, OKAZUMI S, MATSUBARA H, NABEYA Y et al. Thrombocytosis associated with poor prognosis in patients with esophageal carcinoma. J Am Coll Surg 2004; 198: 737-741. http://dx.doi.org/10.1016/j.jamcollsurg.2004.01.022