Short report: High rates of inapparent dengue in older adults in Singapore

American Journal of Tropical Medicine and Hygiene

Volumn 88, Issue 6, 2013, Pages 1065-1069

  Yap, Grace ^a   Li, Chenny ^a   Mutalib, Adeliza ^a   Lai, Yee Ling ^a   Ng, Lee Ching ^a  

^a NATIONAL ENVIRONMENT AGENCY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; BLOOD SAMPLING; CROSS-SECTIONAL STUDY; DENGUE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIDEMIC; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEROPREVALENCE; SINGAPORE; ADOLESCENT; ADULT; CHILD; EPIDEMIOLOGY; MIDDLE AGED; QUESTIONNAIRE; VERY ELDERLY;

IMMUNOGLOBULIN M;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; CROSS-SECTIONAL STUDIES; DENGUE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNOGLOBULIN M; MALE; MIDDLE AGED; QUESTIONNAIRES; SEROEPIDEMIOLOGIC STUDIES; SINGAPORE; YOUNG ADULT;

MLCS; MLOWN;

EID: 84878775862     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.12-0150     Document Type: Article

References (15)

1. Ooi EE, Goh KT, Chee Wang DN, 2003. Effect of increasing age on the trend of dengue and dengue hemorrhagic fever in Singapore. Int J Infect Dis 7: 231-232. (Pubitemid 37314370)
2. Goh KT, 1997. Dengue: a re-emerging infectious disease in Singapore. Ann Acad Med Singapore 26: 664-670. (Pubitemid 128523448)
3. Ong A, Sandar M, Chen MI, Sin LY, 2007. Fatal dengue hemorrhagic fever in adults during a dengue epidemic in Singapore. Int J Infect Dis 11: 263-267. (Pubitemid 46617358)
4. Guzman MG, Kouri G, 2002. Dengue: an update. Lancet Infect Dis 2: 33-42. (Pubitemid 36109304)
5. Endy TP, Chunsuttiwat S, Nisalak A, Libraty DH, Green S, Rothman AL, Vaughn DW, Ennis FA, 2002. Epidemiology of inapparent and symptomatic acute dengue virus infection: a prospective study of primary school children in Kamphaeng Phet, Thailand. Am J Epidemiol 156: 40-51. (Pubitemid 34680622)
6. Chen WJ, Chen SL, Chien LJ, Chen CC, King CC, Harn MR, Hwang KP, Fang JH, 1996. Silent transmission of the dengue virus in southern Taiwan. Am J Trop Med Hyg 55: 12-16.
7. Teixeira Mda G, Barreto ML, Costa Mda C, Ferreira LD, Vasconcelos PF, Cairncross S, 2002. Dynamics of dengue virus circulation: a silent epidemic in a complex urban area. Trop Med Int Health 7: 757-762.
8. Groen J, Koraka P, Velzing J, Copra C, Osterhaus AD, 2000. Evaluation of six immunoassays for detection of dengue virus-specific immunoglobulin M and G antibodies. Clin Diagn Lab Immunol 7: 867-871. (Pubitemid 32244480)
9. Lai YL, Chung YK, Tan HC, Yap HF, Yap G, Ooi EE, Ng LC, 2007. Cost-effective real-time reverse transcriptase PCR (RT-PCR) to screen for dengue virus followed by rapid single-tube multiplex RT-PCR for serotyping of the virus. J Clin Microbiol 45: 935-941. (Pubitemid 46427714)
10. Goh KT, 1998. Seroepidemiology of Dengue Virus Infection in Singapore. Dengue in Singapore. Singapore: WHO Collaborating Centre for Environmental Epidemiology, Ministry of the Environment, 50-72.
11. Ye T, Ang LW, Chow A, Chew SK, 2007. Seroprevalence study on past and recent dengue virus infection in Singapore. Epidemiol News Bull (Singapore) 33: 36-41.
12. Seet RC, Quek AM, Lim EC, 2007. Post-infectious fatigue syndrome in dengue infection. J Clin Virol 38: 1-6. (Pubitemid 44881429)
13. Lye DC, Lee VJ, Sun Y, Leo YS, 2010. The benign nature of acute dengue infection in hospitalized older adults in Singapore. Int J Infect Dis 14: e410-e413.
14. Ginaldi L, De Martinis M, D'Ostilio A, Marini L, Loreto MF, Martorelli V, Quaglino D, 1999. The immune system in the elderly: II. Specific cellular immunity. Immunol Res 20: 109-115.
15. Chan KP, Lau GK, Doraisingham S, Chan YC, 1995. Adult dengue deaths in Singapore. Clin Diagn Virol 4: 213-222.