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Volumn 20, Issue 5, 2012, Pages 162-167

New and investigational antiretroviral drugs for HIV infection: Mechanisms of action and early research findings

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; NEW DRUG;

EID: 84878775158     PISSN: 21615861     EISSN: 21615853     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (22)

References (10)
  • 1
    • 84873090036 scopus 로고    scopus 로고
    • GS-7340 25 mg and 40 mg demonstrate superior efficacy to tenofovir 300 mg in a 10-day monotherapy study of HIV-1+ patients. [Abstract 103.]
    • March 5-8, Washington, DC
    • Ruane P, DeJesus E, Berger D, et al. GS-7340 25 mg and 40 mg demonstrate superior efficacy to tenofovir 300 mg in a 10-day monotherapy study of HIV-1+ patients. [Abstract 103.] 19th Conference on Retroviruses and Opportunistic Infections (CROI). March 5-8, 2012; Washington, DC.
    • (2012) 19th Conference on Retroviruses and Opportunistic Infections (CROI)
    • Ruane, P.1    DeJesus, E.2    Berger, D.3
  • 2
    • 84882414170 scopus 로고    scopus 로고
    • Genotypic and phenotypic correlates of virologic response to the attachment inhibitor BMS-626529 in a short-term monotherapy study with its prodrug BMS-663068. [Abstract 6.]
    • June 5-9, Sitges, Spain
    • Zhou N, Ray N, Healy M, et al. Genotypic and phenotypic correlates of virologic response to the attachment inhibitor BMS-626529 in a short-term monotherapy study with its prodrug BMS-663068. [Abstract 6.] International Workshop on HIV & Hepatitis Virus Drug Resistance. June 5-9, 2012; Sitges, Spain.
    • (2012) International Workshop on HIV & Hepatitis Virus Drug Resistance
    • Zhou, N.1    Ray, N.2    Healy, M.3
  • 3
    • 84866124136 scopus 로고    scopus 로고
    • Pharmacodynamics, safety, and pharmacokinetics of BMS-663068, an oral HIV-1 attachment inhibitor in HIV-1-infected subjects
    • Nettles RE, Schurmann D, Zhu L, et al. Pharmacodynamics, safety, and pharmacokinetics of BMS-663068, an oral HIV-1 attachment inhibitor in HIV-1-infected subjects. J Infect Dis. 2012;206(7):1002-1011.
    • (2012) J Infect Dis. , vol.206 , Issue.7 , pp. 1002-1011
    • Nettles, R.E.1    Schurmann, D.2    Zhu, L.3
  • 4
    • 84878778807 scopus 로고    scopus 로고
    • Cobicistat versus ritonavir as pharmacoenhancers in combination with atazanavir plus tenofovir disoproxil fumarate/ emtricitabine: Phase 3 randomized, double blind, active-controlled trial, week 48 results. [Abstract TUAB0103.]
    • July 22-27, Washington, DC
    • Gallant J, Koenig E, Andrade-Villanueva J, et al. Cobicistat versus ritonavir as pharmacoenhancers in combination with atazanavir plus tenofovir disoproxil fumarate/ emtricitabine: phase 3 randomized, double blind, active-controlled trial, week 48 results. [Abstract TUAB0103.] 19th International AIDS Conference (IAS). July 22-27, 2012; Washington, DC.
    • (2012) 19th International AIDS Conference (IAS)
    • Gallant, J.1    Koenig, E.2    Andrade-Villanueva, J.3
  • 5
    • 84872093991 scopus 로고    scopus 로고
    • Dolutegravir in combination therapy exhibits rapid and sustained antiviral response in ARV-naive adults: 96-week results from SPRING-1 (ING112276). [Abstract 102LB.]
    • March 5-8, Washington, DC
    • Stellbrink HJ, Reynes J, Lazzarin A, et al. Dolutegravir in combination therapy exhibits rapid and sustained antiviral response in ARV-naive adults: 96-week results from SPRING-1 (ING112276). [Abstract 102LB.] 19th Conference on Retroviruses and Opportunistic Infections (CROI). March 5-8, 2012; Washington, DC.
    • (2012) 19th Conference on Retroviruses and Opportunistic Infections (CROI)
    • Stellbrink, H.J.1    Reynes, J.2    Lazzarin, A.3
  • 6
    • 84871107975 scopus 로고    scopus 로고
    • Dolutegravir (DTG; S/GSK1349572) + abacavir/lamivudine once daily statistically superior to tenofovir/emtricitabine/ efavirenz: 48-week results-SINGLE (ING114467). [Abstract H-556b.]
    • September 9-12, San Francisco, CA
    • Walmsley S, Antela A, Clumeck N, et al. Dolutegravir (DTG; S/GSK1349572) + abacavir/lamivudine once daily statistically superior to tenofovir/emtricitabine/ efavirenz: 48-week results-SINGLE (ING114467). [Abstract H-556b.] 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC). September 9-12, 2012; San Francisco, CA.
    • (2012) 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
    • Walmsley, S.1    Antela, A.2    Clumeck, N.3
  • 7
    • 84864387134 scopus 로고    scopus 로고
    • Small-molecule inhibitors of the LEDGF/ p75 binding site of integrase block HIV replication and modulate integrase multimerization
    • Christ F, Shaw S, Demeulemeester J, et al. Small-molecule inhibitors of the LEDGF/ p75 binding site of integrase block HIV replication and modulate integrase multimerization. Antimicrob Agents Chemother. 2012;56(8):4365-4374.
    • (2012) Antimicrob Agents Chemother. , vol.56 , Issue.8 , pp. 4365-4374
    • Christ, F.1    Shaw, S.2    Demeulemeester, J.3
  • 8
    • 84878810820 scopus 로고    scopus 로고
    • Renal safety profile of cobicistat-boosted elvitegravir or atazanavir plus emtricitabine/tenofovir DF in HIV patients. [Abstract H-891.]
    • September 9-12, San Francisco, CA
    • Benson P, Mayer C, Morales-Ramirez J, et al. Renal safety profile of cobicistat-boosted elvitegravir or atazanavir plus emtricitabine/tenofovir DF in HIV patients. [Abstract H-891.] 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC). September 9-12, 2012; San Francisco, CA.
    • (2012) 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
    • Benson, P.1    Mayer, C.2    Morales-Ramirez, J.3
  • 9
    • 84878775917 scopus 로고    scopus 로고
    • Efficacy and safety of elvitegravir/cobicistat/ emtricitabine/tenofovir DF from an integrated analysis of phase 2 and 3 clinical trials. [Abstract H-555.]
    • September 9-12, San Francisco, CA
    • Ward D, Crofoot G, Shamblaw D, et al. Efficacy and safety of elvitegravir/cobicistat/ emtricitabine/tenofovir DF from an integrated analysis of phase 2 and 3 clinical trials. [Abstract H-555.] 52nd Interscience Conference on Antimicrobials and Chemotherapy (ICAAC). September 9-12, 2012. San Francisco, CA.
    • (2012) 52nd Interscience Conference on Antimicrobials and Chemotherapy (ICAAC)
    • Ward, D.1    Crofoot, G.2    Shamblaw, D.3
  • 10
    • 84867651801 scopus 로고    scopus 로고
    • Pharmacokinetics, safety and tolerability of the HIV integrase inhibitor s/gsk1265744 long acting parenteral nanosuspension following single dose administration to healthy adults. [Abstract TUPE040.]
    • July 22-27, Washington, DC
    • Spreen W, Ford SL, Chen S, et al. Pharmacokinetics, safety and tolerability of the HIV integrase inhibitor s/gsk1265744 long acting parenteral nanosuspension following single dose administration to healthy adults. [Abstract TUPE040.] 19th International AIDS Conference (IAS). July 22-27, 2012; Washington, DC.
    • (2012) 19th International AIDS Conference (IAS)
    • Spreen, W.1    Ford, S.L.2    Chen, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.