Can Healthy Fetuses Show Facial Expressions of "Pain" or "Distress"?

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Reissland, Nadja ^a   Francis, Brian ^b   Mason, James ^a  

^a DURHAM UNIVERSITY   (United Kingdom)

^b LANCASTER UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CONTROLLED STUDY; DISTRESS SYNDROME; FACIAL EXPRESSION; FEMALE; FETUS; FETUS MOVEMENT; GESTATIONAL AGE; HUMAN; MALE; MOTOR DEVELOPMENT; MOTOR PERFORMANCE; OUTCOME ASSESSMENT; PAIN; SECOND TRIMESTER PREGNANCY; SEX DIFFERENCE; THIRD TRIMESTER PREGNANCY; ADULT; ECHOGRAPHY; EMBRYOLOGY; FACE; FETUS ECHOGRAPHY; GESTALT THERAPY; HEALTH; PATHOPHYSIOLOGY; PREGNANCY; PSYCHOLOGY; YOUNG ADULT;

ADULT; FACE; FACIAL EXPRESSION; FEMALE; FETAL MOVEMENT; FETUS; GESTALT THEORY; GESTATIONAL AGE; HEALTH; HUMANS; MALE; PAIN; PREGNANCY; ULTRASONOGRAPHY, PRENATAL; YOUNG ADULT;

EID: 84878767335     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065530     Document Type: Article

References (51)

1. Smith RP, Giteau R, Glover V, Fisk NM, (2000) Pain and stress in the human fetus. Eur J Obstet Gynecol Reprod Biol 92: 161-165.
2. Lee SJ, Ralston HJP, Drey EA, Partridge JC, Rosen MA, (2005) Fetal pain: A systematic multidisciplinary review of the evidence. JAMA 294: 947-95.
3. Anand KJS, Hickey PR, (1987) Pain and its effects in the human neonate and fetus. New Engl J Med 317: 1321-1329.
4. Benatar D, Benatar M, (2001) A pain in the fetus: towards ending confusion about fetal pain. Bioethics 15: 57-76.
5. Kostovic I, Judas M, (2010) The development of the subplate and thalamocortical connections in the human foetal brain. Acta Paediatr 99: 1119-1127.
6. Mathews PJ, Mathews LJ, (2003) Assessment and management of pain in infants. Postgrad Med J 79: 438-443.
7. Oberlander TF, Grunau RE, Fitzgerald C, Whitfield MF, (2002) Does parenchymal brain injury affect biobehavioral pain responses in very low birth weight infants at 32 weeks' postconceptional age? Pediatrics 110: 570-576.
8. Waxman SG, (1996) Clinical observations on the emotional motor system. Prog Brain Res 107: 595-604.
9. Craig KD, Prkachin KM, Grunau RE (2001) Facial expression of pain. In: Turk DC, Melzack R, editors. Handbook of Pain Assessment. 2nd ed. New York, NY: Guilford Press. pp 153-169.
10. Craig KD, Hadjistavropoulos HD, Grunau RV, Whitfield MF, (1994) A comparison of two measures of facial activity during pain in the newborn child. J Pediatr Psychol 19: 305-318.
11. Bartocci M, Bergqvist LL, Lagercrantz H, Anand KJS, (2006) Pain activates cortical areas in the preterm newborn brain. Pain 122: 109-17.
12. Slater R, Cantarella A, Gallella S, Worley A, Meek J, et al. (2006) Cortical pain responses in human infants. J. Neurosci 26: 3662-3666.
13. Slater R, Cantarella A, Franck L, Meek J, Fitzgerald M, (2008) How well do clinical pain assessment tools reflect pain in infants? PLoS Medicine 5: e129.
14. Derbyshire SWG, (2010) Foetal pain? Best Pract Res Cl Ga 24: 647-655.
15. Craig KD, Whitfield MF, Grunau RVE, Linton J, Hadjistavropoulos HD, (1993) Pain in the preterm neonate: behavioural and physiological indices. Pain 52: 287-299.
16. Grunau RVE, Johnston CC, Craig KD, (1990) Neonatal facial and cry responses to invasive and non-invasive procedures. Pain 42: 295-305.
17. Reissland N, Francis B, Mason J, Lincoln K, (2011) Do Facial Expressions Develop before Birth? PLoS ONE 6(8): e24081 doi:10.1371/journal.pone.0024081.
18. Hepper PG, Shannon EA, Dornan JC, (1997) Sex differences in fetal mouth movements. Lancet 350: 1820.
19. Miller JL, Macedonia C, Sonies BC, (2006) Sex differences in prenatal oral-motor function and development. Dev Med Child Neurol 48: 465-470.
20. Hepper PG, Dornan JC, Lynch C, (2012) Sex differences in fetal habituation. Dev Sci 15: 373-383.
21. Humprey T (1967) Reflex activity in the oral and facial area of the human fetus. In Bosma JF, editor. Second symposium on oral sensation and perception Springfield IL. Charles C. Thomas. 195-255.
22. Azumendi G, Kurjak A, (2003) Three-dimensional and four-dimensional sonography in the study of the fetal face. Ultrasound Obst Gyn 3: 160-169.
23. Yan F, Dai SY, Akther N, Kuno A, Yanagihara T, et al. (2006) Four-dimensional sonographic assessment of fetal facial expression early in the third trimester. Int J Gynaecol Obstet 94: 108-113.
24. Piontelli A (2010) Development of normal fetal movements. Springer Verlag, Italia.
25. Ekman P, Friesen WV (1978) Manual for the Facial Action Coding System. Paolo Alto, CA: Consultant Psychologists Press.
26. Reissland N, Francis B, Mason J, (2012) Development of Fetal Yawn Compared with Non-Yawn Mouth Openings from 24-36 Weeks Gestation. PLoS ONE 7(11): e50569 doi:10.1371/journal.pone.0050569.
27. Craig KD, Grunau RVE (1991) Developmental issues: Infants and toddlers. In Bush JP, Harkins SW, editors. Pain in children: Clinical and research issues from a developmental perspective. New York: Springer-Verlag. 171-193.
28. Prkachin KM (2005) the consistency of facial expressions of pain: a comparison across modalities. In Ekman P, Rosenberg EL, editors.What the face reveals, CUP. 181-197.
29. LeResche L, (1982) Facial expression in pain: A study of candid photographs. J Nonverbal Behav 7: 46-56.
30. LeResche L, Dworkin SF, (1988) Facial expressions of pain and emotions in chronic TMD patients. Pain 35: 71-78.
31. Patrick CJ, Craig KD, Prkachin KM, (1986) Observer judgements of acute pain: Facial action determinants. J Pers Soc Psychol 50: 1291-98.
32. Craig KD, Patrick CJ, (1985) Facial expression during induced pain. J Pers Soc Psychol 48: 1080-1091.
33. Fernadez-Dols JM, Crivelli C, (2013) Emotion and Expression: Naturalistic Studies. Emotion Review 5: 24-29.
34. Agresti A (2010) Analysis of Ordinal Categorical Data (2nd Edition). New York: Wiley.
35. Tutz G, Hennevogl W, (1996) Random effects in ordinal regression models. Comput Stat Data An 22: 537-557.
36. Hartzel J, Agresti A, Caffo B, (2001) Multinomial logit random effects models. Stat Model 1: 81-102.
37. Christensen RHB (2011) Analysis of ordinal data with cumulative link models- estimation with the R-package ordinal. 2011. Available: http://cran.r-project.org/web/packages/ordinal/vignettes/clm_intro.pdf. Accessed 2011 Dec 15.
38. De Vries JIP, Visser GH, Prechtl H, (1982) The emergence of fetal behaviour. I. Qualitative aspects. Early Hum Dev 7: 301-322.
39. Roodenburg PJ, Wladimiroff JW, van Es A, Prechtl HF, (1991) Classification and quantitative aspects of fetal movements during the second half of normal pregnancy. Early Hum Dev 25: 19-35.
40. Kurjak A, Vecek N, Hafner T, Bozek T, Funduk-Kurjak B, et al. (2002) Prenatal diagnosis: What does four-dimensional ultrasound add? J Perinat Med 30: 57-62.
41. Kurjak A, Azumedi G, (2003) Fetal hand movement and facial expressions in normal pregnancy studies by four dimensional sonography. J Perinat Med 31: 496-508.
42. Kurjak A, Stanojevic M, Azumendi G, Carrera JM, (2005) The potential of four-dimensional (4D) ultrasonography in the assessment of fetal awareness. J Perinat Med 33: 46-53.
43. Kurjak A, Andonotopo W, Hafner T, Salihagic Kadic A, Stanojevic M, et al. (2006) Normal standards for fetal neurobehavioral developments -longitudinal quantification by four-dimensional sonography. J Perinat Med 34: 56-65.
44. Kurjak A, Tikvica A, Sanojevic M, Miskovic B, Ahmed B, et al. (2008) The assessment of fetal neurobehavior by three-dimensional and four-dimensional ultrasound. J Matern Fetal Neonatal Med 21: 675-684.
45. Hata T, Dai S-Y, Marumo G (2010) Ultrasound for Evaluation of Fetal Neurobehavioural Development: from 2-D to 4-D Ultrasound. Infant Child Dev 19: Special Issue, 99-118.
46. Mellor DJ, Diesch TJ, Gunn AJ, Bennet L, (2005) The importance of "awareness" to understand fetal pain. Brain Res Rev 49: 455-471.
47. Kawai N, (2010) Towards a New Study on Associative Learning in Human Fetuses: Fetal Associative Learning in Primates. Infant Child Dev 19: 55-59.
48. Kisilevsky BS, Hains SMJ, Lee K, Xie X, Huang H, et al. (2003) Effects of experience on fetal voice recognition. Psych Sci 14: 220-224.
49. Kisilevsky BS, Hains SMJ, (2010) Exploring the Relationship between Fetal Heart Rate and Cognition. Infant Child Dev 19: 60-75.
50. Kurjak A, Abo-Yaqoub S, Stanojevic M, Yigiter AB, Vasilj O, et al. (2010) The potential of 4D sonography in the assessment of fetal neurobehavior - multicentric study in high-risk pregnancies J Perinat Med. 38: 77-82.
51. Giannakoulopoulos X, Sepulveda W, Kourtis P, Glover V, Fisk NM, (1994) Fetal plasma cortisol and beta-endorphin response to intrauterine needling. Lancet 344: 77-81.