Heart rate recovery and heart rate variability are unchanged in patients with coronary artery disease following 12 weeks of highintensity interval and moderate-intensity endurance exercise training

Applied Physiology, Nutrition and Metabolism

Volumn 38, Issue 6, 2013, Pages 644-650

  Currie, Katharine D ^a   Rosen, Lee M ^a   Millar, Philip J ^b   McKelvie, Robert S ^a,c   MacDonald, Maureen J ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c HAMILTON HEALTH SCIENCES   (Canada)

Author keywords

Cardiovascular disease; Exercise testing; Heart rate; Rehabilitation

Indexed keywords

CORONARY ARTERY DISEASE; ENDURANCE; EXERCISE; HEART; HEART RATE; HUMAN; KINESIOTHERAPY;

CORONARY ARTERY DISEASE; EXERCISE; EXERCISE THERAPY; HEART; HEART RATE; HUMANS; PHYSICAL ENDURANCE;

EID: 84878763860     PISSN: 17155312     EISSN: 17155320     Source Type: Journal    
DOI: 10.1139/apnm-2012-0354     Document Type: Article

References (44)

1. Antman, E.M., Anbe, D.T., Armstrong, P.W., Bates, E.R., Green, L.A., Hand, M., et al. 2004. ACC/AHA guidelines for the management of patients with STelevation myocardial infarction-executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1999 Guidelines for the Management of Patients With Acute Myocardial Infarction). Can. J. Cardiol. 20(10): 977-1025. PMID:15332148.
2. Ardic, I., Kaya, M.G., Yarlioglues, M., Dogdu, O., Buyukoglan, H., Kalay, N., et al. 2011. Impaired heart rate recovery index in patients with sarcoidosis. Chest, 139(1): 60-68. doi:10.1378/chest.09-3022. PMID:20595456.
3. Bigger, J.T., Jr., Fleiss, J.L., Rolnitzky, L.M., Steinman, R.C., and Schneider, W.J. 1991. Time course of recovery of heart period variability after myocardial infarction. J. Am. Coll. Cardiol. 18(7): 1643-1649. doi:10.1016/0735-1097(91) 90497-W. PMID:1960309.
4. Borg, G. 1998. Borg's Perceived Exertion and Pain scales. Human Kinetics, Champaign, Illinois.
5. Cole, C.R., Blackstone, E.H., Pashkow, F.J., Snader, C.E., and Lauer, M.S. 1999. Heart-rate recovery immediately after exercise as a predictor of mortality. N. Engl. J. Med. 341(18): 1351-1357. doi:10.1056/NEJM199910283411804. PMID: 10536127.
6. Cole, C.R., Foody, J.M., Blackstone, E.H., and Lauer, M.S. 2000. Heart rate recovery after submaximal exercise testing as a predictor of mortality in a cardiovascularly healthy cohort. Ann. Intern. Med. 132(7): 552-555. PMID:10744592.
7. Dimopoulos, S., Anastasiou-Nana, M., Sakellariou, D., Drakos, S., Kapsimalakou, S., Maroulidis, G., et al. 2006. Effects of exercise rehabilitation program on heart rate recovery in patients with chronic heart failure. Eur. J. Cardiovasc. Prev. Rehabil. 13(1): 67-73. doi:10.1097/01.hjr.0000198449.20775.7c. PMID:16449866.
8. Giallauria, F., De Lorenzo, A., Pilerci, F., Manakos, A., Lucci, R., Psaroudaki, M., et al. 2006a. Long-term effects of cardiac rehabilitation on end-exercise heart rate recovery after myocardial infarction. Eur. J. Cardiovasc. Prev. Rehabil. 13(4): 544-550. doi:10.1097/01.hjr.0000216547.07432.fb. PMID:16874143.
9. Giallauria, F., Lucci, R., Pietrosante, M., Gargiulo, G., De Lorenzo, A., D'Agostino, M., et al. 2006b. Exercise-based cardiac rehabilitation improves heart rate recovery in elderly patients after acute myocardial infarction. J. Gerontol. A Biol. Sci. Med. Sci. 61(7): 713-717. doi:10.1093/gerona/61.7.713. PMID:16870634.
10. Hai, J.J., Siu, C.W., Ho, H.H., Li, S.W., Lee, S., and Tse, H.F. 2010. Relationship between changes in heart rate recovery after cardiac rehabilitation on cardiovascular mortality in patients with myocardial infarction. Heart Rhythm, 7(7): 929-936. doi:10.1016/j.hrthm.2010.03.023. PMID:20346416.
11. Hao, S.C., Chai, A., and Kligfield, P. 2002. Heart rate recovery response to symptom-limited treadmill exercise after cardiac rehabilitation in patients with coronary artery disease with and without recent events. Am. J. Cardiol. 90(7): 763-765. doi:10.1016/S0002-9149(02)02607-3. PMID:12356394.
12. Hood, M.S., Little, J.P., Tarnopolsky, M.A., Myslik, F., and Gibala, M.J. 2011. Low-volume interval training improves muscle oxidative capacity in sedentary adults. Med. Sci. Sports Exerc. 43(10): 1849-1856. doi:10.1249/MSS. 0b013e3182199834. PMID:21448086.
13. Iellamo, F., Legramante, J.M., Massaro, M., Raimondi, G., and Galante, A. 2000. Effects of a residential exercise training on baroreflex sensitivity and heart rate variability in patients with coronary artery disease: A randomized, controlled study. Circulation, 102(21): 2588-2592. doi:10.1161/01.CIR.102.21.2588. PMID:11085961.
14. Imai, K., Sato, H., Hori, M., Kusuoka, H., Ozaki, H., Yokoyama, H., et al. 1994. Vagally mediated heart rate recovery after exercise is accelerated in athletes but blunted in patients with chronic heart failure. J. Am. Coll. Cardiol. 24(6): 1529-1535. doi:10.1016/0735-1097(94)90150-3. PMID:7930286.
15. Jouven, X., Empana, J.P., Schwartz, P.J., Desnos, M., Courbon, D., and Ducimetiere, P. 2005. Heart-rate profile during exercise as a predictor of sudden death. N. Engl. J. Med. 352(19): 1951-1958. doi:10.1056/NEJMoa043012. PMID:15888695.
16. Kleiger, R.E., Miller, J.P., Bigger, J.T., Jr., and Moss, A.J. 1987. Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. Am. J. Cardiol. 59(4): 256-262. doi:10.1016/0002-9149(87)90795-8. PMID:3812275.
17. Kligfield, P., McCormick, A., Chai, A., Jacobson, A., Feuerstadt, P., and Hao, S.C. 2003. Effect of age and gender on heart rate recovery after submaximal exercise during cardiac rehabilitation in patients with angina pectoris, recent acute myocardial infarction, or coronary bypass surgery. Am. J. Cardiol. 92(5): 600-603. doi:10.1016/S0002-9149(03)00733-1. PMID:12943886.
18. Kontopoulos, A.G., Athyros, V.G., Papageorgiou, A.A., Skeberis, V.M., Basayiannis, E.C., and Boudoulas, H. 1997. Effect of angiotensin-converting enzyme inhibitors on the power spectrum of heart rate variability in postmyocardial infarction patients. Coron. Artery Dis. 8(8-9): 517-524. PMID: 9431480.
19. La Rovere, M.T., Bigger, J.T., Jr., Marcus, F.I., Mortara, A., and Schwartz, P.J. 1998. Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction. ATRAMI (Autonomic Tone and Reflexes After Myocardial Infarction) Investigators. Lancet, 351(9101): 478-484. doi:10.1016/S0140-6736(97)11144-8. PMID:9482439.
20. Lahiri, M.K., Kannankeril, P.J., and Goldberger, J.J. 2008. Assessment of autonomic function in cardiovascular disease: physiological basis and prognostic implications. J. Am. Coll. Cardiol. 51(18): 1725-1733. doi:10.1016/j.jacc.2008.01. 038. PMID:18452777.
21. Laing, S.T., Gluckman, T.J., Weinberg, K.M., Lahiri, M.K., Ng, J., and Goldberger, J.J. 2011. Autonomic effects of exercise-based cardiac rehabilitation. J. Cardiopulm. Rehabil. Prev. 31(2): 87-91. doi:10.1097/HCR.0b013 e3181f1fda0. PMID:20861747.
22. Little, J.P., Safdar, A., Wilkin, G.P., Tarnopolsky, M.A., and Gibala, M.J. 2010. A practical model of low-volume high-intensity interval training induces mitochondrial biogenesis in human skeletal muscle: potential mechanisms. J. Physiol. 588(6): 1011-1022. doi:10.1113/jphysiol.2009.181743. PMID:20100740.
23. Little, J.P., Gillen, J.B., Percival, M.E., Safdar, A., Tarnopolsky, M.A., Punthakee, Z., et al. 2011. Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetes. J. Appl. Physiol. 111(6): 1554-1560. doi:10.1152/ japplphysiol.00921.2011. PMID:21868679.
24. Lucini, D., Milani, R.V., Costantino, G., Lavie, C.J., Porta, A., and Pagani, M. 2002. Effects of cardiac rehabilitation and exercise training on autonomic regulation in patients with coronary artery disease. Am. Heart J. 143(6): 977-983. doi:10.1067/mhj.2002.123117. PMID:12075252.
25. Malik, M., Bigger, J.T., Camm, A.J., Kleiger, R.E., Malliani, A., Moss, A, J., and Schwartz, P.J. 1996. Heart rate variability: standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Eur. Heart J. 17(3): 354-381.
26. Millar, P.J., Cotie, L.M., St Amand, T., McCartney, N., and Ditor, D.S. 2010. Effects of autonomic blockade on nonlinear heart rate dynamics. Clin. Auton. Res. 20(4): 241-247. doi:10.1007/s10286-010-0058-6. PMID:20213265.
27. Moholdt, T., Aamot, I.L., Granoien, I., Gjerde, L., Myklebust, G., Walderhaug, L., et al. 2012. Aerobic interval training increases peak oxygen uptake more than usual care exercise training in myocardial infarction patients: a randomized controlled study. Clin. Rehabil. 26(1): 33-44. doi:10.1177/0269215511405229. PMID:21937520.
28. Munk, P.S., Staal, E.M., Butt, N., Isaksen, K., and Larsen, A.I. 2009. High-intensity interval training may reduce in-stent restenosis following percutaneous coronary intervention with stent implantation: a randomized controlled trial evaluating the relationship to endothelial function and inflammation. Am. Heart J. 158(5): 734-741. doi:10.1016/j.ahj.2009.08.021. PMID:19853690.
29. Munk, P.S., Butt, N., and Larsen, A.I. 2010. High-intensity interval exercise training improves heart rate variability in patients following percutaneous coronary intervention for angina pectoris. Int. J. Cardiol. 145(2): 312-314. doi:10. 1016/j.ijcard.2009.11.015. PMID:19962772.
30. Myers, J., Prakash, M., Froelicher, V., Do, D., Partington, S., and Atwood, J.E. 2002. Exercise capacity and mortality among men referred for exercise testing. N. Engl. J. Med. 346(11): 793-801. doi:10.1056/NEJMoa011858. PMID: 11893790.
31. Niemela, M.J., Airaksinen, K.E., and Huikuri, H.V. 1994. Effect of beta-blockade on heart rate variability in patients with coronary artery disease. J. Am. Coll. Cardiol. 23(6): 1370-1377. doi:10.1016/0735-1097(94)90379-4. PMID:8176095.
32. Riahi, S., Christensen, J.H., Toft, E., Skou, H.A., and Schmidt, E.B. 2002. HMG-CoA reductase inhibitors improve heart rate variability in patients with a previous myocardial infarction. Pharmacol Res. 45(6): 479-483. doi:10.1006/phrs. 2002.0988. PMID:12162949.
33. Roger, V.L., Go, A.S., Lloyd-Jones, D.M., Benjamin, E.J., Berry, J.D., Borden, W.B., et al. 2012. Heart disease and stroke statistics-2012 update: a report from the American Heart Association. Circulation, 125(1): e2-e220. doi:10.1161/CIR. 0b013e31823ac046. PMID:22179539.
34. Rognmo, Ø., Hetland, E., Helgerud, J., Hoff, J., and Slørdahl, S.A. 2004. High intensity aerobic interval exercise is superior to moderate intensity exercise for increasing aerobic capacity in patients with coronary artery disease. Eur. J. Cardiovasc. Prev. Rehabil. 11(3): 216-222. doi:10.1097/01.hjr.0000131677. 96762.0c. PMID:15179103.
35. Savin, W.M., Davidson, D.M., and Haskell, W.L. 1982. Autonomic contribution to heart rate recovery from exercise in humans. J. Appl. Physiol. 53(6): 1572-1575. PMID:7153152.
36. Shetler, K., Marcus, R., Froelicher, V.F., Vora, S., Kalisetti, D., Prakash, M., et al. 2001. Heart rate recovery: validation and methodologic issues. J. Am. Coll. Cardiol. 38(7): 1980-1987. doi:10.1016/S0735-1097(01)01652-7. PMID:11738304.
37. Smith, S.C., Jr., Allen, J., Blair, S.N., Bonow, R.O., Brass, L.M., Fonarow, G.C., et al. 2006. AHA/ACC guidelines for secondary prevention for patients with coronary and other atherosclerotic vascular disease: 2006 update: endorsed by the National Heart, Lung, and Blood Institute. Circulation, 113(19): 2363-2372. doi:10.1161/CIRCULATIONAHA.106.174516. PMID:16702489.
38. Stone, J.A., McCartney, N., Millar, P.J., Tremblay, L., and Warburton, D.E.R. 2009. Risk stratification, exercise prescription, and program safety. In Risk stratification, exercise prescription, and program safety. Edited by J.A. Stone. Canadian Association of Cardiac Rehabilitation, Winnipeg, Manitoba. pp. 341-385.
39. Tsai, S.W., Lin, Y.W., and Wu, S.K. 2005. The effect of cardiac rehabilitation on recovery of heart rate over one minute after exercise in patients with coronary artery bypass graft surgery. Clin. Rehabil. 19(8): 843-849. doi:10.1191/ 0269215505cr915oa. PMID:16323383.
40. Tsuji, H., Venditti, F.J., Jr., Manders, E.S., Evans, J.C., Larson, M.G., Feldman, C.L., et al. 1996. Determinants of heart rate variability. J. Am. Coll. Cardiol. 28(6): 1539-1546. doi:10.1016/S0735-1097(96)00342-7. PMID:8917269.
41. Vivekananthan, D.P., Blackstone, E.H., Pothier, C.E., and Lauer, M.S. 2003. Heart rate recovery after exercise is a predictor of mortality, independent of the angiographic severity of coronary disease. J. Am. Coll. Cardiol. 42(5): 831-838. doi:10.1016/S0735-1097(03)00833-7. PMID:12957428.
42. Warburton, D.E., McKenzie, D.C., Haykowsky, M.J., Taylor, A., Shoemaker, P., Ignaszewski, A.P., et al. 2005. Effectiveness of high-intensity interval training for the rehabilitation of patients with coronary artery disease. Am. J. Cardiol. 95(9): 1080-1084. doi:10.1016/j.amjcard.2004.12.063. PMID:15842976.
43. Wisloff, U., Stoylen, A., Loennechen, J.P., Bruvold, M., Rognmo, O., Haram, P.M., et al. 2007. Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart failure patients: a randomized study. Circulation, 115(24): 3086-3094. doi:10.1161/CIRCULATIONAHA.106.675041. PMID:17548726.
44. Wu, S.K., Lin, Y.W., Chen, C.L., and Tsai, S.W. 2006. Cardiac rehabilitation vs. home exercise after coronary artery bypass graft surgery: a comparison of heart rate recovery. Am. J. Phys. Med. Rehabil. 85(9): 711-717. doi:10.1097/01. phm.0000228597.64057.66. PMID:16924183.