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Volumn 108, Issue 4, 2013, Pages 501-507

In vitro and in vivo antimalarial activity and cytotoxicity of extracts, fractions and a substance isolated from the amazonian plant tachia grandiflora (Gentianaceae)

Author keywords

Amplexine (djalonenol); Decussating; Human fibroblasts; Plasmodium berghei; Plasmodium falciparum

Indexed keywords

ANTIMALARIAL AGENT; PLANT EXTRACT;

EID: 84878751197     PISSN: 00740276     EISSN: 16788060     Source Type: Journal    
DOI: 10.1590/0074-0276108042013017     Document Type: Article
Times cited : (17)

References (35)
  • 1
    • 0028344958 scopus 로고
    • A new rapid and simple non-radioactive assay to monitor and determine the proliferation of lymphocytes: An alternative to [3H] thymidine incorporation assay
    • Ahmed SA, Gogal Jr RM, Walsh JE 1994. A new rapid and simple non-radioactive assay to monitor and determine the proliferation of lymphocytes: an alternative to [3H] thymidine incorporation assay. J Immunol Methods 15: 211-224.
    • (1994) J Immunol Methods , vol.15 , pp. 211-224
    • Ahmed, S.A.1    Gogal, R.M.2    Walsh, J.E.3
  • 5
    • 0026320689 scopus 로고
    • Antimalarial activity of crude extracts from Brazilian plants studied in vivo in Plasmodium berghei-infected mice and in vitro against Plasmodium falciparum in culture
    • Carvalho LH, Brandão MGL, Santos-Filho D, Lopes JLC, Krettli AU 1991. Antimalarial activity of crude extracts from Brazilian plants studied in vivo in Plasmodium berghei-infected mice and in vitro against Plasmodium falciparum in culture. Braz J Med Biol Res 24: 1113-1123.
    • (1991) Braz J Med Biol Res , vol.24 , pp. 1113-1123
    • Carvalho, L.H.1    Brandão, M.G.L.2    Santos-Filho, D.3    Lopes, J.L.C.4    Krettli, A.U.5
  • 6
    • 0026365934 scopus 로고
    • Antimalarial chemotherapy with natural products and chemically defined molecules
    • Carvalho LH, Krettli AU 1991. Antimalarial chemotherapy with natural products and chemically defined molecules. Mem Inst Oswaldo Cruz 86 (Suppl. II): 181-184.
    • (1991) Mem Inst Oswaldo Cruz , vol.86 , Issue.SUPPL. II , pp. 181-184
    • Carvalho, L.H.1    Krettli, A.U.2
  • 9
    • 0012946673 scopus 로고    scopus 로고
    • Chemotaxonomy and pharmacology of gentianaceae
    • L Struwe, V Albert (eds.), Cambridge University Press, Cambridge
    • Jensen SR, Schripsema J 2002. Chemotaxonomy and pharmacology of gentianaceae. In L Struwe, V Albert (eds.), Gentianaceae - Systematics and natural history, Cambridge University Press, Cambridge, p. 573-631.
    • (2002) Gentianaceae - Systematics and Natural History , pp. 573-631
    • Jensen, S.R.1    Schripsema, J.2
  • 10
    • 75749142726 scopus 로고    scopus 로고
    • Phytochemical and antimalarial studies on Swertia alata Royale
    • Karan M, Bhatnagar S, Wangtak P, Vasisht K 2005. Phytochemical and antimalarial studies on Swertia alata Royale. Acta Horticulturae 675: 139-145.
    • (2005) Acta Horticulturae , vol.675 , pp. 139-145
    • Karan, M.1    Bhatnagar, S.2    Wangtak, P.3    Vasisht, K.4
  • 11
    • 0035522812 scopus 로고    scopus 로고
    • The search for new antimalarial drugs from plants used to treat fever and malaria or plants randomly selected: A Review
    • Krettli AU, Andrade-Neto VF, Brandão MGL, Ferrari WMS 2001. The search for new antimalarial drugs from plants used to treat fever and malaria or plants randomly selected: a Review. Mem Inst Oswaldo Cruz 96: 1033-1042.
    • (2001) Mem Inst Oswaldo Cruz , vol.96 , pp. 1033-1042
    • Krettli, A.U.1    Andrade-Neto, V.F.2    Brandão, M.G.L.3    Ferrari, W.M.S.4
  • 12
    • 0018704491 scopus 로고
    • Synchronization of Plasmodium falciparum erythrocytic stages in culture
    • Lambros C, Vanderberg JP 1979. Synchronization of Plasmodium falciparum erythrocytic stages in culture. J Parasitol 65: 418-420.
    • (1979) J Parasitol , vol.65 , pp. 418-420
    • Lambros, C.1    Vanderberg, J.P.2
  • 13
    • 7144246458 scopus 로고
    • The neotropical genus Tachia (Gentianaceae)
    • Maguire B, Weaver Jr RE 1975. The neotropical genus Tachia (Gentianaceae). J Arnold Arbor 56: 103-125.
    • (1975) J Arnold Arbor , vol.56 , pp. 103-125
    • Maguire, B.1    Weaver, R.E.2
  • 15
    • 0004025772 scopus 로고    scopus 로고
    • Medicinal plants of Brazil, RA de Filipps (ed.)
    • Reference Publication, Algonac
    • Mors WB, Rizzini CT, Pereira NA 2000. Medicinal plants of Brazil, RA de Filipps (ed.), Medicinal plants of the world 6, Reference Publication, Algonac, 501 pp.
    • (2000) Medicinal Plants of the World , vol.6 , pp. 501
    • Mors, W.B.1    Rizzini, C.T.2    Pereira, N.A.3
  • 17
    • 0028858747 scopus 로고
    • Monoterpene diol, iridoid glucoside, and dibenzo-α-pyrone from Anthocleista djalononensis
    • Onocha AP, Okorie AD, Connolly DJ, Roycroft DS 1995. Monoterpene diol, iridoid glucoside, and dibenzo-α-pyrone from Anthocleista djalononensis. Phytochemistry 40: 1183-1189.
    • (1995) Phytochemistry , vol.40 , pp. 1183-1189
    • Onocha, A.P.1    Okorie, A.D.2    Connolly, D.J.3    Roycroft, D.S.4
  • 18
    • 73449127328 scopus 로고    scopus 로고
    • Rutgers University/National Institute on Amazon Research, New Brunswick/Manaus
    • Peters W, Kinkade MP, Pohlit AM, Struwe L 2005. Tachia field guide, Rutgers University/National Institute on Amazon Research, New Brunswick/Manaus, 1 pp.
    • (2005) Tachia Field Guide , pp. 1
    • Peters, W.1    Kinkade, M.P.2    Pohlit, A.M.3    Struwe, L.4
  • 25
    • 0018262277 scopus 로고
    • Drug sensitivity of Plasmodium falciparum. An in vitro microtechinique
    • Rieckmann KH, Sax LJ, Campbell GH, Mrema JE 1978. Drug sensitivity of Plasmodium falciparum. An in vitro microtechinique. Lancet 1: 22-23.
    • (1978) Lancet , vol.1 , pp. 22-23
    • Rieckmann, K.H.1    Sax, L.J.2    Campbell, G.H.3    Mrema, J.E.4
  • 26
    • 26044483551 scopus 로고    scopus 로고
    • Xanthones as antimalarial agents: Discovery, mode of action and optimization
    • Riscoe M, Kelly JX, Winter R 2005. Xanthones as antimalarial agents: discovery, mode of action and optimization. Curr Med Chem 12: 2539-2549.
    • (2005) Curr Med Chem , vol.12 , pp. 2539-2549
    • Riscoe, M.1    Kelly, J.X.2    Winter, R.3
  • 32
  • 33
    • 29144433462 scopus 로고    scopus 로고
    • Two new Brazilian species of Tachia (Gentianaceae: Helieae)
    • Struwe L, Kinkade MP, Maas PJM 2005. Two new Brazilian species of Tachia (Gentianaceae: Helieae). Blumea 50: 457-462.
    • (2005) Blumea , vol.50 , pp. 457-462
    • Struwe, L.1    Kinkade, M.P.2    Maas, P.J.M.3
  • 35
    • 84878759220 scopus 로고    scopus 로고
    • WHO - World Health Organization, In vitro micro-test (Mark III) for the assessment of the response of Plasmodium falciparum to chloroquine, mefloquine, quinine, amodiaquine, sulfadoxine/pyrimetamine and artemisinin. Available from
    • WHO - World Health Organization 2001. In vitro micro-test (Mark III) for the assessment of the response of Plasmodium falciparum to chloroquine, mefloquine, quinine, amodiaquine, sulfadoxine/pyrimetamine and artemisinin. Available from: whqlibdoc.who.int/hq/2001/a76873.pdf.
    • (2001)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.