Cardiopoietry in motion: Primed mesenchymal stem cells for ischemic cardiomyopathy

Journal of the American College of Cardiology

Volumn 61, Issue 23, 2013, Pages 2339-2340

  Murry, Charles E ^a,b   Palpant, Nathan J ^a,b   Maclellan, W Robb ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

bone marrow; cardiopoiesis; ischemic cardiomyopathy; regenerative medicine; stem cells

Indexed keywords

AZACITIDINE; CYTOKINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MEF2C; TRANSCRIPTION FACTOR MESP 1; TRANSCRIPTION FACTOR NKX2.5; UNCLASSIFIED DRUG;

BONE MARROW CELL; CARDIOPOIETIC STEM CELL THERAPY; CELL DIFFERENTIATION; EVIDENCE BASED MEDICINE; EXPOSURE; FEASIBILITY STUDY; HEART ARRHYTHMIA; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE ENDSYSTOLIC VOLUME; HEART MUSCLE CELL; HEART PERFORMANCE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; MESENCHYMAL STEM CELL TRANSPLANTATION; MUSCLE DEVELOPMENT; NONHUMAN; NOTE; OXYGEN CONSUMPTION; PATIENT SAFETY; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURGICAL TECHNIQUE; TISSUE REPAIR;

EID: 84878709361     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2013.03.028     Document Type: Editorial

References (14)

1. R. Bolli, A.R. Chugh, and D. D'Amario Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial Lancet 378 2011 1847 1857
2. R.R. Makkar, R.R. Smith, and K. Cheng Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): A prospective, randomised phase 1 trial Lancet 379 2012 895 904
3. D.M. Clifford, S.A. Fisher, and S.A. Brunskill Stem cell treatment for acute myocardial infarction Cochrane Database Syst Rev 2 2012 Feb 15 CD006536
4. V. Schächinger, S. Erbs, and A. Elsässer Improved clinical outcome after intracoronary administration of bone-marrow-derived progenitor cells in acute myocardial infarction: final 1-year results of the REPAIR-AMI trial Eur Heart J 27 2006 2775 2783 (Pubitemid 44871463)
5. J.H. Loughran, A.R. Chugh, I. Ismail, and R. Bolli Stem cell therapy: promising treatment in heart failure? Curr Heart Fail Rep 10 2013 73 80
6. M.A. Laflamme, and C.E. Murry Heart regeneration Nature 473 2011 326 335
7. F.P. Barry, and J.M. Murphy Mesenchymal stem cells: clinical applications and biological characterization International J Biochem Cell Biol 36 2004 568 584 (Pubitemid 38324589)
8. J. Bartunek, A. Behfar, and D. Dolatabadi Cardiopoietic stem cell therapy in heart failure: the C-CURE (Cardiopoietic stem Cell therapy in heart failURE) multicenter randomized trial with lineage-specified biologics J Am Coll Cardiol 61 2013 2329 2338
9. A. Behfar, S. Yamada, and R. Crespo-Diaz Guided cardiopoiesis enhances therapeutic benefit of bone marrow human mesenchymal stem cells in chronic myocardial infarction J Am Coll Cardiol 56 2010 721 734
10. A. Behfar, and A. Terzic Derivation of a cardiopoietic population from human mesenchymal stem cells yields cardiac progeny Nat Clin Pract Cardiovasc Med 3 Suppl 1 2006 S78 S82
11. A. Behfar, R.S. Faustino, D.K. Arrell, P.P. Dzeja, C. Perez-Terzic, and A. Terzic Guided stem cell cardiopoiesis: discovery and translation J Mol Cell Cardiol 45 2008 523 529
12. R.S. Faustino, and A. Terzic Interactome of a cardiopoietic precursor J Cardiovasc Transl Res 1 2008 120 126
13. C. Nesselmann, N. Ma, and K. Bieback Mesenchymal stem cells and cardiac repair J Cell Mol Med 12 2008 1795 1810
14. M. Gnecchi, Z. Zhang, A. Ni, and V.J. Dzau Paracrine mechanisms in adult stem cell signaling and therapy Circ Res 103 2008 1204 1219