The METABOLIC Study: Multidimensional assessment of health and functional status in older patients with type 2 diabetes taking oral antidiabetic treatment

Diabetes and Metabolism

Volumn 39, Issue 3, 2013, Pages 236-243

  Maggi, S ^a   Noale, M ^a   Pilotto, A ^b   Tiengo, A ^c   Cavallo Perin, P ^d   Crepaldi, G ^a  

^a CNR   (Italy)

^b Sports Medicine Unit   (Italy)

^c UNIVERSITY OF PADOVA   (Italy)

^d UNIVERSITY OF TURIN   (Italy)

Author keywords

Functional limitations; Hypoglycaemia; METABOLIC Study; Older patients; Type 2 diabetes

Indexed keywords

ALPHA GLUCOSIDASE INHIBITOR; BIGUANIDE DERIVATIVE; DIPEPTIDYL PEPTIDASE IV INHIBITOR; INSULIN; ORAL ANTIDIABETIC AGENT; SULFONYLUREA;

AGED; ARTICLE; DAILY LIFE ACTIVITY; DIABETIC PATIENT; DIASTOLIC BLOOD PRESSURE; DISABILITY SEVERITY; DISABLED PERSON; DISEASE DURATION; FEMALE; FUNCTIONAL STATUS; HEALTH STATUS; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROPATHY; NON INSULIN DEPENDENT DIABETES MELLITUS; NUTRITIONAL STATUS; PHYSICAL DISABILITY;

ADMINISTRATION, ORAL; AGE FACTORS; AGED; AGED, 80 AND OVER; COHORT STUDIES; DIABETES COMPLICATIONS; DIABETES MELLITUS, TYPE 2; FEMALE; HEALTH STATUS; HUMANS; HYPOGLYCEMIA; HYPOGLYCEMIC AGENTS; MALE; QUESTIONNAIRES;

EID: 84878666539     PISSN: 12623636     EISSN: 18781780     Source Type: Journal    
DOI: 10.1016/j.diabet.2013.02.003     Document Type: Article

References (29)

1. Gregg E.W., Beckles G.L., Williamson D.F., Leveille S.G., Langlois J.A., Engelgau M.M., et al. Diabetes and physical disability among US adults. Diabetes Care 2000, 23:1272-1277.
2. Gregg E.W., Mangione C.M., Cauley J.A. Diabetes and incidence of functional disability in older women. Diabetes Care 2002, 25:61-67.
3. Volpato S., Ferrucci L., Blaum C., Ostir G., Cappola A., Fried L.P., et al. Progression of lower-extremity disability in older women with diabetes: the Women's Health and Aging Study. Diabetes Care 2003, 26:70-75.
4. Maggi S., Noale M., Gallina P., Marzari C., Bianchi D., Limongi F., et al. Physical disability among older Italians with diabetes. The ILSA Study. Diabetologia 2004, 47:1957-1962.
5. Abbatecola A.M., Maggi S., Paolisso G. New approaches to treating type 2 diabetes mellitus in the elderly: role of incretin therapies. Drugs Aging 2008, 25:913-925.
6. Garza H. Minimizing the risk of hypogycaemia in older adults: a focus on long-term care. Consult Pharm 2009, 24(Suppl. B):18-24.
7. Daniel W.W. Biostatistics: a foundation for analysis in the health sciences 1999, John Wiley & Sons, New York. 7th ed.
8. Pilotto A., Ferrucci L., Franceschi M., D'Ambrosio L.P., Scarcelli C., Cascavilla L., et al. Development and validation of a multidimensional prognostic index for one-year mortality from comprehensive geriatric assessment in hospitalized older patients. Rejuvenation Res 2008, 11:151-161.
9. Katz S., Ford A.B., Moskowitz R.W., Jackson B.A., Jaffe M.W. Studies of illness in the aged. The index of ADL: a standardized measure of biological and psychological function. JAMA 1963, 185:914-919.
10. Lawton M.P., Brody E.M. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969, 9:179-186.
11. Pfeiffer E. A short portable mental status questionnaire for the assessment of organic brain deficit in elderly patients. J Am Geriatr Soc 1975, 23:433-441.
12. Bliss M.R., McLaren R., Exton-Smith A.N. Mattresses for preventing pressure sores in geriatric patients. Mon Bull Minist Health Public Health Lab Serv 1966, 25:238-268.
13. Conwell Y., Forbes N.T., Cox C., Caine E.D. Validation of a measure of physical illness burden at autopsy: the Cumulative Illness Rating Scale. J Am Geriatr Soc 1993, 41:38-41.
14. Vellas B., Guigoz Y., Garry P.J., Nourhashemi F., Bennahum D., Lauque S., et al. The Mini Nutritional Assessment (MNA) and its use in grading the nutritional state of elderly patients. Nutrition 1999, 15:116-122.
15. Pilotto A., Addante F., Ferrucci L., Leandro G., D'Onofrio G., Corritore M., et al. The multidimensional prognostic index predicts short- and long-term mortality in hospitalized geriatric patients with pneumonia. J Gerontol A Biol Sci Med Sci 2009, 64:880-887.
16. Pilotto A., Sancarlo D., Panza F., Paris F., D'Onofrio G., Cascavilla L., et al. The Multidimensional Prognostic Index (MPI), based on a comprehensive geriatric assessment predicts short- and long-term mortality in hospitalized older patients with dementia. J Alzheimers Dis 2009, 18:191-199.
17. Pilotto A., Addante F., Franceschi M., Leandro G., Rengo G., D'Ambrosio P., et al. Multidimensional Prognostic Index based on a comprehensive geriatric assessment predicts short-term mortality in older patients with heart failure. Circ Heart Fail 2010, 3:14-20.
18. Sancarlo D., Pilotto A., Panza F., Copetti M., Longo M.G., D'Ambrosio P., et al. A Multidimensional Prognostic Index (MPI) based on a comprehensive geriatric assessment predicts short- and long-term all-cause mortality in older hospitalized patients with transient ischemic attack. J Neurol 2012, 259:670-678.
19. Pilotto A., Panza F., Sancarlo D., Paroni G., Maggi S., Ferrucci L. Usefulness of the multidimensional prognostic index (MPI) in the management of older patients with chronic kidney disease. J Nephrol 2012, 25(Suppl. 19):S79-S84.
20. Aucella F., Stoico L., Cicchella A., Gesuete A., Greco A., Grandaliano G., et al. Comprehensive geriatric assessment in the hemodialysis elderly population. J Nephrol 2012, 25(Suppl. 19):S85-S89.
21. Yourman L.C., Lee S.J., Schonberg M.A., Widera E.W., Smith A.K. Prognostic indices for older adults: a systematic review. JAMA 2012, 307:182-192.
22. Van Dieren S., Beulens J.W., van der Schouw Y.T., Grobbee D.E., Neal B. The global burden of diabetes and its complications: an emerging pandemic. Eur J Cardiovasc Prev Rehabil 2010, 17:S3-S8.
23. Schwartz A.V., Hillier T.A., Sellmeyer D.E., Resnick H.E., Gregg E., Ensrud K.E., et al. Older women with diabetes have a higher risk of falls: a prospective study. Diabetes Care 2002, 25(10):1749-1754.
24. Bots M.L., Witteman J.C.M., Hofman A., de Jong P.T., Grobbee D.E. Low diastolic blood pressure and atherosclerosis in elderly subjects. Arch Intern Med 1996, 156:843-848.
25. Cummings S.R., Nevitt M.C., Browner W.S., Stone K., Fox K.M., Ensrud K.E., et al. Risk factors for hip fracture in white women. N Engl J Med 1995, 332:767-773.
26. Kahonen-Vare M., Brunni-Hakala S., Lindroos M., Pitkala K., Strandberg T., Tilvis R. Left ventricular hypertrophy and blood pressure as predictors of cognitive decline in old age. Aging Clin Exp Res 2004, 16:147-152.
27. Molander L., Gustafson Y., Lövheim H. Longitudinal associations between blood pressure and dementia in the very old. Dement Geriatr Cogn Disord 2010, 30:269-276.
28. Guo Z., Viitanen M., Winblad B. Low blood pressure and five-year mortality in a Stockholm cohort of the very old: possible confounding by cognitive impairment and other factor. AJPH 1997, 87:623-628.
29. American Geriatrics Society British Geriatrics Society Guideline for the prevention of falls in older persons. J Am Geriatr Soc 2001, 49:664-672. American Academy of Orthopedic Surgeons Panel on Falls Prevention.