A New Functional Site W115 in CdtA Is Critical for Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Li, Lu ^a   Ding, Cheng ^a   Duan, Jun lan ^a   Yang, Mi fang ^a   Sun, Ying ^a   Wang, Xiao qian ^a   Xu, Yan ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYTOLETHAL DISTENDING TOXIN; CYTOLETHAL DISTENDING TOXIN A; UNCLASSIFIED DRUG; BACTERIAL TOXIN; PROTEIN BINDING; RECOMBINANT PROTEIN;

AGGREGATIBACTER ACTINOMYCETEMCOMITANS; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL CYCLE ARREST; COMPLEX FORMATION; CONTROLLED STUDY; FEMALE; GEL PERMEATION CHROMATOGRAPHY; HELA CELL; HUMAN; HUMAN CELL; NONHUMAN; POINT MUTATION; PROTEIN ASSEMBLY; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS; TOXIN ANALYSIS; TOXIN STRUCTURE; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; CELL CYCLE CHECKPOINT; CHEMISTRY; CHO CELL LINE; CRICETULUS; DRUG EFFECTS; ESCHERICHIA COLI; GENE EXPRESSION; GENETICS; HAMSTER; HELA CELL LINE; METABOLISM; MOLECULAR GENETICS; PATHOGENICITY; STRUCTURE ACTIVITY RELATION;

EUKARYOTA;

AGGREGATIBACTER ACTINOMYCETEMCOMITANS; AMINO ACID SEQUENCE; ANIMALS; BACTERIAL TOXINS; CELL CYCLE CHECKPOINTS; CHO CELLS; CRICETINAE; CRICETULUS; ESCHERICHIA COLI; GENE EXPRESSION; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; PROTEIN BINDING; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84878666537     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065729     Document Type: Article

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