Treatment of malignant ascites with a combination of chemotherapy drugs and intraperitoneal perfusion of verapamil

Cancer Chemotherapy and Pharmacology

Volumn 71, Issue 6, 2013, Pages 1585-1590

  Jia, Weidong ^a   Zhu, Zhiqiang ^a   Zhang, Tengyue ^b   Fan, Gaofei ^b   Fan, Pingsheng ^b   Liu, Yabei ^b   Duan, Qiaohong ^b  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b Anhui Cancer Hospital   (China)

Author keywords

Ascites; Clinical study; Intraperitoneal perfusion; Multidrug resistance; Verapamil

Indexed keywords

ANTACID AGENT; ANTIEMETIC AGENT; CISPLATIN; DIURETIC AGENT; FLUOROURACIL; OXALIPLATIN; RECOMBINANT INTERLEUKIN 2; VERAPAMIL;

ADHESION; ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTHRALGIA; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLADDER CANCER; BREAST CANCER; CANCER CELL; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER REGRESSION; CANCER SURVIVAL; COLORECTAL CANCER; CONTROLLED STUDY; DRUG EFFICACY; DRUG FEVER; DRUG SAFETY; ESOPHAGUS CANCER; FEMALE; GALLBLADDER CANCER; GASTROINTESTINAL DISEASE; HUMAN; HUMAN CELL; LARYNX CANCER; LEUKOPENIA; MAJOR CLINICAL STUDY; MALE; MALIGNANT ASCITES; MYALGIA; PANCREAS CANCER; PRIORITY JOURNAL; QUALITY OF LIFE; SIDE EFFECT; THROMBOCYTOPENIA; TREATMENT DURATION; TREATMENT OUTCOME;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ASCITES; DISEASE-FREE SURVIVAL; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; INFUSIONS, PARENTERAL; MALE; MIDDLE AGED; NEOPLASMS; PERFUSION; QUALITY OF LIFE; TREATMENT OUTCOME; VERAPAMIL;

EID: 84878642549     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-013-2158-1     Document Type: Article

References (17)

1. Harmon RL, Sugarbaker PH (2005) Prognostic indicators in peritoneal carcinomatosis from gastrointestinal cancer. Int Semin Surg Oncol 2:3-12
2. Sangisetty SL, Miner TJ (2012) Malignant ascites: a review of prognostic factors, pathophysiology and therapeutic measures. World J Gastrointest Surg 4:87-95
3. Saada E, Follana P, Peyrade F, Mari V, Francois E (2011) Pathogenesis and management of refractory malignant ascites. Bull Cancer 98:679-687 (in French)
4. Szakacs G, Paterson JK, Ludwig JA, Booth-Genthe C, Gottesman MM (2006) Targeting multidrug resistance in cancer. Nat Rev Drug Discov 5:219-234
5. Geng M, Ma T, YeE ZB, Ji YB, Lou GY, Xi WQ, Jiang JS, Xia HQ, Li H (2006) In vitro chemo-sensitivity MTT assay guided intraperitoneal chemotherapy for malignant ascites. Zhonghua Zhong Liu Za Zhi 28:460-463 (in Chinese)
6. Ford JM, Hait WN (1990) Pharmacology of drugs that alter multidrug resistance in cancer. Pharmacol Rev 42:155-199
7. Ak I, Gulbas Z, Ocak S, Kaya E, Alatas F, Vardareli E, Metintas M (2007) TC-99 m MIBI SPECT imaging in patients with lung carcinoma: is it a functional probe of multidrug resistance genes? J Comput Assist Tomogr 31:795-799
8. Sun X, Yin Q, Chen D, Dong X, Zhou L, Zhang H, Fan P (2004) Determination of verapamil in dog serum and tissues by reversed-phase high performance liquid chromatography. Se Pu 22:255-257 (in Chinese)
9. World Health Organisation (1979) WHO handbook for reporting results of cancer treatment. Report number 48
10. Markman M, Cleary S, Howell SB, Lucas WE (1986) Complications of extensive adhesion formation after intraperitoneal chemotherapy. Surg Gynecol Obstet 162:445-448
11. Kefford RF, Woods RL, Fox RM, Tatterall MH (1980) Intracavitary adriamycin nitrogen mustard and tetracycline in the control of malignant effusions: a randomized study. Med J Aust 2:447-448
12. Baumert C, Hilgeroth A (2009) Recent advances in the development of P-gp inhibitors. Anticancer Agents Med Chem 9:415-436
13. Alexander RH, Kelsen KD, Tepper TC (1997) Cancer of the stomach. In: DeVita VT, Hellman S, Rosenberg SA (eds) Cancer: principles and practice of oncology, 5th edn. Lippincott Raven Publishers, Philadelphia, pp 971-1251
14. Huang J, Duan Q, Fan P, Ji C, Lv Y, Lin X, Qian L, Yu X (2011) Clinical evaluation of targeted arterial infusion of verapamil in the interventional chemotherapy of primary hepatocellular carcinoma. Cell Biochem Biophys 59:127-132
15. Huang J, Yang SM (2009) Clinical efficacy of chemotherapy combined with verapamil in pancreatic carcinoma. Shandong Med Pharm J 49:33-34 (in Chinese)
16. Liu Y, Lu Z, Fan P, Duan Q, Li Y, Tong S, Hu B, Lv R, Hu L, Zhuang J (2011) Clinical efficacy of chemotherapy combined with verapamil in metastatic colorectal patients. Cell Biochem Biophys 61:393-398
17. Pingsheng F, Tengyue Z, Qiang H, Qiang W, Xin S, Liting Q (2012) Basic and clinical research on the therapeutic effect of intervention in primary liver cancer by targeted intra-arterial verapamil infusion. Cell Biochem Biophys 62:59-67