Lipopolysaccharide-binding protein: A potential marker of febrile urinary tract infection in childhood

Pediatric Nephrology

Volumn 28, Issue 7, 2013, Pages 1091-1097

  Tsalkidou, Evanthia A ^a   Roilides, Emmanouel ^b   Gardikis, Stefanos ^a   Trypsianis, Gregory ^c   Kortsaris, Alexandros ^c   Chatzimichael, Athanasios ^a   Tentes, Ioannis ^c  

^a DEMOCRITUS UNIVERSITY OF THRACE MEDICAL SCHOOL   (Greece)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^c DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

Author keywords

C reactive protein; Children; Erythrocyte sedimentation rate; Interleukin 6; Lipopolysaccharide binding protein; Procalcitonin; Urinary tract infection

Indexed keywords

C REACTIVE PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE BINDING PROTEIN; PROCALCITONIN;

ARTICLE; CHILD; CONTROLLED STUDY; DIAGNOSTIC VALUE; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; FEVER; HUMAN; INFANT; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; SCHOOL CHILD; SENSITIVITY AND SPECIFICITY; URINARY TRACT INFECTION;

ACUTE-PHASE PROTEINS; ADOLESCENT; AREA UNDER CURVE; BIOLOGICAL MARKERS; BLOOD SEDIMENTATION; C-REACTIVE PROTEIN; CALCITONIN; CARRIER PROTEINS; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; CHILD; CHILD, PRESCHOOL; EARLY DIAGNOSIS; FEMALE; FEVER; HUMANS; INFANT; INFLAMMATION MEDIATORS; INTERLEUKIN-6; LEUKOCYTE COUNT; MALE; MEMBRANE GLYCOPROTEINS; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; PROTEIN PRECURSORS; ROC CURVE; URINARY TRACT INFECTIONS;

EID: 84878631028     PISSN: 0931041X     EISSN: 1432198X     Source Type: Journal    
DOI: 10.1007/s00467-013-2432-9     Document Type: Article

References (23)

1. Saadeh SA, Mattoo TK (2011) Managing urinary tract infections. Pediatr Nephrol 26:1967-1976
2. Lutter SA, Currie ML, Mitz LB, Greenbaum LA (2005) Antibiotic resistance patterns in children hospitalized for urinary tract infections. Arch Pediatr Adolesc Med 159:924-928
3. Dandona P, Nix D, Wilson MF, Aljada SG, Love J, Assicot M (1994) Procalcitonin increase after endotoxin infection in normal subjects. J Clin Endocrinol Metab 79:1605-1608
4. Benador N, Siegrist C-A, Gendrel D, Greder C, Sakran W, Halevy R (1998) Procalcitonin is a marker of severity of renal lesions in pyelonephritis. Pediatrics 102:1422-1425
5. Smolkin V, Koren A, Raz R, Colodner R, Sakran W, Halevy R (2002) Procalcitonin as a marker of acute pyelonephritis in infants and children. Pediatr Nephrol 17:409-412
6. Prat C, Dominguez J, Rodrigo C, Giménez M, Azuara M, Jiménez O, Gali N, Ausina V (2003) Elevated serum procalcitonin values correlate with renal scarring in children with urinary tract infection. Pediatr Infect Dis J 22:438-442
7. Gervaix A, Galletto-Lacour A, Gueron T, Vadas L, Zamora S, Suter S, Girardin E (2001) Usefulness of procalcitonin and C-reactive protein rapid tests for the management of children with urinary tract infection. Pediatr Infect Dis J 20:507-511
8. Benson M, Jodal U, Agace W, Hellström M, Mårild S, Rosberg S, Sjöström M, Wettergren B, Jönsson S, Svanborg C (1996) Interleukin (IL)-6 and IL-8 in children with febrile urinary tract infection and asymptomatic bacteriuria. J Infect Dis 174:1080-1084
9. Fünfstück R, Franke S, Hellberg M, Ott U, Knöfel B, Straube E, Sommer M, Hacker J (2001) Secretion of cytokines by uroepithelial cells stimulated by Escherichia coli and Citrobacter spp. Int J Antimicrob Agents 17:253-258
10. Kassir K, Vargas-Shiraishi O, Zaldivar F, Berman M, Singh J (2001) Cytokine profiles of pediatric patients treated with antibiotics for pyelonephritis: potential therapeutic impact. Clin Diagn Lab Immunol 8:1060-1063
11. Roilides E, Papachristou F, Gioulekas E, Tsaparidou S, Karatzas N, Sotiriou J, Tsiouris J (1999) Increased urine interleukin-6 concentrations correlate with pyelonephritic changes on 99mTc-dimercaptosuccinic acid scans in neonates with urinary tract infections. J Infect Dis 180:904-907
12. Otto G, Braconier J, Andreasson A, Svanborg C (1999) Interleukin-6 and disease severity in patients with bacteremic and non bacteremic febrile urinary tract infection. J Infect Dis 179:172-179
13. Pavcnik-Arnol M, Hojker S, Derganc M (2007) Lipopolysaccharide-binding protein, lipopolysaccharide, and soluble CD14 in sepsis of critically ill neonates and children. Intensive Care Med 33:1025-1032
14. Berner R, Fürll B, Stelter F, Dröse J, Müller HP, Schütt C (2002) Elevated levels of lipopolysaccharide-binding protein and soluble CD14 in plasma in neonatal early-onset sepsis. Clin Diagn Lab Immunol 9:440-445
15. Kohara J, Tsuneyoshi N, Gauchat JF, Kimoto M, Fukudome K (2006) Preparation and characterization of truncated human lipopolysaccharide-binding protein in Escherichia coli. Protein Expr Purif 49:276-283
16. Myc A, Buck J, Gonin J, Reynolds B, Hammerling U, Emanuel D (1997) The level of lipopolysaccharide-binding protein is significantly increased in plasma in patients with the systemic inflammatory response syndrome. Clin Diagn Lab Immunol 4:113-116
17. Pavcnik-Arnol M, Hojker S, Derganc M (2004) Lipopolysaccharide-binding protein in critically ill neonates and children with suspected infection: comparison with procalcitonin, interleukin-6, and C-reactive protein. Intensive Care Med 30:1454-1460
18. Schröder NW, Heine H, Alexander C, Manukyan M, Eckert J, Hamann L, Göbel UB, Schumann RR (2004) Lipopolysaccharide-binding protein binds to triacylated and diacylated lipopeptides and mediates innate immune responses. J Immunol 173:2683-2691
19. Blairon L, Wittebole X, Laterre PF (2003) Lipopolysaccharide-binding protein serum levels in patients with severe sepsis due to Gram-positive and fungal infections. J Infect Dis 187:287-291
20. Luoto R, Kalliomaki M, Latinen K, Delzene NM, Cani PD, Salminen S, Isolauri E (2011) Initial dietary and microbiological environments deviate in normal-weight compared to overweight children at 10 years of age. J Pediatr Gastroenterol Nutr 52:90-95
21. Pecile P, Miorin E, Romanello C, Falleti E, Valent F, Giacomuzzi F, Tenore A (2004) Procalcitonin: a marker of severity of acute pyelonephritis among children. Pediatrics 114:e249-e254
22. Jantausch BA, O'Donnell R, Wiedermann BL (2000) Urinary interleukin-6 and interleukin-8 in children with urinary tract infection. Pediatr Nephrol 15:236-240
23. Galanakis E, Bitsori M, Dimitriou H, Giannakopoulou C, Karkavitsas NS, Kalmanti M (2007) Serum and urine interleukin-6 and transforming growth factor-beta1 in young infants with pyelonephritis. Int Urol Nephrol 39:581-585