Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge

Nature Genetics

Volumn 45, Issue 5, 2013, Pages 468-469

  Plenge, Robert M ^a,b   Greenberg, Jeffrey D ^c   Mangravite, Lara M ^d   Derry, Jonathan M ^d   Stahl, Eli A ^e   Coenen, Marieke J ^f   Barton, Anne ^g   Padyukov, Leonid ^h   Klareskog, Lars ^h   Gregersen, Peter K ⁱ   Mariette, Xavier ^j   Moreland, Larry W ^k   Bridges, S Louis ^l   De Vries, Niek ^m   Huizinga, Tom W ⁿ   Guchelaar, Henk Jan ⁿ   Friend, Stephen H ^d   Stolovitzky, Gustavo ^o  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d SAGE BIONETWORKS   (United States)

^e MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^f RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^g UNIVERSITY OF MANCHESTER   (United Kingdom)

^h KAROLINSKA INSTITUTE   (Sweden)

ⁱ FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^j UNIVERSITÉ PARIS SACLAY   (France)

^k UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^l The University of Alabama at Birmingham   (United States)

^m UNIVERSITY OF AMSTERDAM   (Netherlands)

ⁿ LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^o IBM T J WATSON RESEARCH CENTER   (United States)

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Author keywords

[No Author keywords available]

Indexed keywords

DISEASE MODIFYING ANTIRHEUMATIC DRUG; TUMOR NECROSIS FACTOR ALPHA INHIBITOR;

ACCURACY; ALGORITHM; AUTOIMMUNE DISEASE; BREAST CANCER; CANCER SURVIVAL; CONSENSUS; CROWDSOURCING; GENETIC ANALYSIS; GENETICS; GENOMICS; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFORMED CONSENT; KNOWLEDGE; LEARNING; LETTER; MEDICAL RESEARCH; PEER REVIEW; PREDICTION; PRIORITY JOURNAL; PUBLIC-PRIVATE PARTNERSHIP; QUALITY CONTROL; REMISSION; RHEUMATOID ARTHRITIS; SIMULATION; STATISTICAL SIGNIFICANCE; TREATMENT RESPONSE;

EID: 84878568206     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2623     Document Type: Letter

References (7)

1. Derry, J.M.J. et al. Nat. Genet. 44, 127-130 (2012).
2. Margolin, A.A. et al. Sci. Transl. Med. 5, 181re1 (2013).
3. Wadman, M. Nature 490, 15 (2012).
4. Costello, J.C. & Stolovitzky, G. Clin. Pharmacol. Ther. 93, 396-398 (2013)
5. McInnes, I.B. & Schett, G. N. Engl. J. Med. 365, 2205-2219 (2011).
6. Cui, J. et al. PLoS Genet. published online, http://dx.doi.org/10.1371/ journal.pgen.1003394 (28 March 2013).
7. Stahl, E.A. et al. Nat. Genet. 44, 483-489 (2012).