메뉴 건너뛰기




Volumn 346, Issue 7910, 2013, Pages

Diagnostic accuracy of conventional or age adjusted D-dimer cut-off values in older patients with suspected venous thromboembolism: Systematic review and meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

D DIMER;

EID: 84878540471     PISSN: None     EISSN: 17561833     Source Type: Journal    
DOI: 10.1136/bmj.f2492     Document Type: Article
Times cited : (276)

References (57)
  • 1
    • 4143121708 scopus 로고    scopus 로고
    • D-dimer for the exclusion of acute venous thrombosis and pulmonary embolism: A systematic review
    • Stein PD, Hull RD, Patel KC, Olson RE, Ghali WA, Brant R, et al. D-dimer for the exclusion of acute venous thrombosis and pulmonary embolism: a systematic review. Ann Intern Med 2004;140:589-602.
    • (2004) Ann Intern Med , vol.140 , pp. 589-602
    • Stein, P.D.1    Hull, R.D.2    Patel, K.C.3    Olson, R.E.4    Ghali, W.A.5    Brant, R.6
  • 3
    • 54249137800 scopus 로고    scopus 로고
    • The importance of clinical probability assessment in interpreting a normal d-dimer in patients with suspected pulmonary embolism
    • Gibson NS, Sohne M, Gerdes VE, Nijkeuter M, Buller HR. The importance of clinical probability assessment in interpreting a normal d-dimer in patients with suspected pulmonary embolism. Chest 2008;134:789-93.
    • (2008) Chest , vol.134 , pp. 789-793
    • Gibson, N.S.1    Sohne, M.2    Gerdes, V.E.3    Nijkeuter, M.4    Buller, H.R.5
  • 4
    • 34547865346 scopus 로고    scopus 로고
    • D-dimer concentration increases with age reducing the clinical value of the D-dimer assay in the elderly
    • DOI 10.1111/j.1445-5994.2007.01388.x
    • Harper PL, Theakston E, Ahmed J, Ockelford P. D-dimer concentration increases with age reducing the clinical value of the D-dimer assay in the elderly. Intern Med J 2007;37:607-13. (Pubitemid 47262895)
    • (2007) Internal Medicine Journal , vol.37 , Issue.9 , pp. 607-613
    • Harper, P.L.1    Theakston, E.2    Ahmed, J.3    Ockelford, P.4
  • 5
    • 23444438717 scopus 로고    scopus 로고
    • The challenge of diagnosing pulmonary embolism in elderly patients: Influence of age on commonly used diagnostic tests and strategies
    • DOI 10.1111/j.1532-5415.2005.53309.x
    • Righini M, Le Gal G, Perrier A, Bounameaux H. The challenge of diagnosing pulmonary embolism in elderly patients: influence of age on commonly used diagnostic tests and strategies. J Am Geriatr Soc 2005;53:1039-45. (Pubitemid 41647605)
    • (2005) Journal of the American Geriatrics Society , vol.53 , Issue.6 , pp. 1039-1045
    • Righini, M.1    Le Gal, G.2    Perrier, A.3    Bounameaux, H.4
  • 6
    • 77951708399 scopus 로고    scopus 로고
    • Potential of an age adjusted D-dimer cut-off value to improve the exclusion of pulmonary embolism in older patients: A retrospective analysis of three large cohorts
    • Douma RA, Le Gal G, Sohne M, Righini M, Kamphuisen PW, Perrier A, et al. Potential of an age adjusted D-dimer cut-off value to improve the exclusion of pulmonary embolism in older patients: a retrospective analysis of three large cohorts. BMJ 2010;340:c1475.
    • (2010) BMJ , vol.340
    • Douma, R.A.1    Le Gal, G.2    Sohne, M.3    Righini, M.4    Kamphuisen, P.W.5    Perrier, A.6
  • 7
    • 20444454279 scopus 로고    scopus 로고
    • Reduced efficacy of clinical probability score and D-dimer assay in elderly subjects suspected of having deep vein thrombosis
    • DOI 10.1111/j.1365-2141.2005.05515.x
    • Schutgens RE, Haas FJ, Biesma DH. Reduced efficacy of clinical probability score and D-dimer assay in elderly subjects suspected of having deep vein thrombosis. Br J Haematol 2005;129:653-7. (Pubitemid 40825827)
    • (2005) British Journal of Haematology , vol.129 , Issue.5 , pp. 653-657
    • Schutgens, R.E.G.1    Haas, F.J.L.M.2    Biesma, D.H.3
  • 8
    • 0032874669 scopus 로고    scopus 로고
    • Plasma (d)-dimer testing improves the management of thromboembolic disease in hospitalized patients
    • DOI 10.1016/S0049-3848(99)00042-0, PII S0049384899000420
    • Barro C, Bosson JL, Pernod G, Carpentier PH, Polack B. Plasma D-dimer testing improves the management of thromboembolic disease in hospitalized patients. Thromb Res 1999;95:263-9. (Pubitemid 29428158)
    • (1999) Thrombosis Research , vol.95 , Issue.5 , pp. 263-269
    • Barro, C.1    Bosson, J.-L.2    Pernod, G.3    Carpentier, P.H.4    Polack, B.5
  • 9
    • 34250789839 scopus 로고    scopus 로고
    • Integrated strategies for the diagnosis of venous thromboembolism
    • DOI 10.1111/j.1538-7836.2007.02493.x, State of the Art 2007: XXI Congress of the International Society on Thrombosis and Haemostasis
    • Wells PS. Integrated strategies for the diagnosis of venous thromboembolism. J Thromb Haemost 2007;5( Suppl 1):41-50. (Pubitemid 46958814)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.SUPPL. 1 , pp. 41-50
    • Wells, P.S.1
  • 10
    • 77955245843 scopus 로고    scopus 로고
    • Contemporary management of pulmonary embolism: The answers to ten questions
    • Bounameaux H. Contemporary management of pulmonary embolism: the answers to ten questions. J Intern Med 2010;268:218-31.
    • (2010) J Intern Med , vol.268 , pp. 218-231
    • Bounameaux, H.1
  • 11
    • 84857522361 scopus 로고    scopus 로고
    • European and American suspected and confirmed pulmonary embolism populations: Comparison and analysis
    • Penaloza A, Kline J, Verschuren F, Courtney DM, Zech F, Derrien B, et al. European and American suspected and confirmed pulmonary embolism populations: comparison and analysis. J Thromb Haemost 2012;10:375-81.
    • (2012) J Thromb Haemost , vol.10 , pp. 375-381
    • Penaloza, A.1    Kline, J.2    Verschuren, F.3    Courtney, D.M.4    Zech, F.5    Derrien, B.6
  • 12
    • 34548062283 scopus 로고    scopus 로고
    • Influence of age on the cost-effectiveness of diagnostic strategies for suspected pulmonary embolism
    • DOI 10.1111/j.1538-7836.2007.02667.x
    • Righini M, Nendaz M, Le Gal G, Bounameaux H, Perrier A. Influence of age on the cost-effectiveness of diagnostic strategies for suspected pulmonary embolism. J Thromb Haemost 2007;5:1869-77. (Pubitemid 47288944)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.9 , pp. 1869-1877
    • Righini, M.1    Nendaz, M.2    Le Gal, G.3    Bounameaux, H.4    Perrier, A.5
  • 13
    • 0033804833 scopus 로고    scopus 로고
    • Effects of age on the performance of common diagnostic tests for pulmonary embolism
    • Righini M, Goehring C, Bounameaux H, Perrier A. Effects of age on the performance of common diagnostic tests for pulmonary embolism. Am J Med 2000;109:357-61.
    • (2000) Am J Med , vol.109 , pp. 357-361
    • Righini, M.1    Goehring, C.2    Bounameaux, H.3    Perrier, A.4
  • 14
    • 67749116462 scopus 로고    scopus 로고
    • An age-adapted approach for the use of D-dimers in the exclusion of deep venous thrombosis
    • Haas FJ, Schutgens RE, Biesma DH. An age-adapted approach for the use of D-dimers in the exclusion of deep venous thrombosis. Am J Hematol 2009;84:488-91.
    • (2009) Am J Hematol , vol.84 , pp. 488-491
    • Haas, F.J.1    Schutgens, R.E.2    Biesma, D.H.3
  • 15
    • 18344417430 scopus 로고    scopus 로고
    • Diagnosis of deep venous thrombosis in the elderly: A higher D-dimer cut-off value is better?
    • Aguilar C, Martinez A, Martinez A, Del RC, Vazquez M. Diagnosis of deep venous thrombosis in the elderly: a higher D-dimer cut-off value is better? Haematologica 2001;86:E28.
    • (2001) Haematologica , vol.86
    • Aguilar, C.1    Martinez, A.2    Martinez, A.3    Del, R.C.4    Vazquez, M.5
  • 17
    • 84855313450 scopus 로고    scopus 로고
    • The combination of four different clinical decision rules and an age-adjusted D-dimer cut-off increases the number of patients in whom acute pulmonary embolism can safely be excluded
    • Van Es J, Mos I, Douma R, Erkens P, Durian M, Nizet T, et al. The combination of four different clinical decision rules and an age-adjusted D-dimer cut-off increases the number of patients in whom acute pulmonary embolism can safely be excluded. Thromb Haemost 2012;107:167-71.
    • (2012) Thromb Haemost , vol.107 , pp. 167-171
    • Van Es, J.1    Mos, I.2    Douma, R.3    Erkens, P.4    Durian, M.5    Nizet, T.6
  • 18
    • 84862148015 scopus 로고    scopus 로고
    • Validation of two age dependent D-dimer cut-off values for exclusion of deep vein thrombosis in suspected elderly patients in primary care: Retrospective, cross sectional, diagnostic analysis
    • Schouten HJ, Koek HL, Oudega R, Geersing GJ, Janssen KJ, van Delden JJ et al. Validation of two age dependent D-dimer cut-off values for exclusion of deep vein thrombosis in suspected elderly patients in primary care: retrospective, cross sectional, diagnostic analysis. BMJ 2012;344:e2985.
    • (2012) BMJ , vol.344
    • Schouten, H.J.1    Koek, H.L.2    Oudega, R.3    Geersing, G.J.4    Janssen, K.J.5    Van Delden, J.J.6
  • 19
    • 84867244944 scopus 로고    scopus 로고
    • Age-dependent D-dimer cut-off value increases the number of older patients in whom deep vein thrombosis can be safely excluded
    • Douma RA, Tan M, Schutgens R, Bates SM, Perrier A, Legnani C, et al. Age-dependent D-dimer cut-off value increases the number of older patients in whom deep vein thrombosis can be safely excluded. Haematologica 2012;97:1507-13.
    • (2012) Haematologica , vol.97 , pp. 1507-1513
    • Douma, R.A.1    Tan, M.2    Schutgens, R.3    Bates, S.M.4    Perrier, A.5    Legnani, C.6
  • 20
    • 10344224024 scopus 로고    scopus 로고
    • Clinical usefulness of D-dimer depending on clinical probability and cutoff value in outpatients with suspected pulmonary embolism
    • DOI 10.1001/archinte.164.22.2483
    • Righini M, Aujesky D, Roy PM, Cornuz J, de Moerloose P, Bounameaux H, et al. Clinical usefulness of D-dimer depending on clinical probability and cutoff value in outpatients with suspected pulmonary embolism. Arch Intern Med 2004;164:2483-7. (Pubitemid 39628077)
    • (2004) Archives of Internal Medicine , vol.164 , Issue.22 , pp. 2483-2487
    • Righini, M.1    Aujesky, D.2    Roy, P.-M.3    Cornuz, J.4    De Moerloose, P.5    Bounameaux, H.6    Perrier, A.7
  • 21
    • 0035068478 scopus 로고    scopus 로고
    • Should the D-dimer cut-off value be increased in elderly patients suspected of pulmonary embolism?
    • Righini M, de Moerloose P, Reber G, Perrier A, Bounameaux H. Should the D-dimer cut-off value be increased in elderly patients suspected of pulmonary embolism? Thromb Haemost 2001;85:744.
    • (2001) Thromb Haemost , vol.85 , pp. 744
    • Righini, M.1    De Moerloose, P.2    Reber, G.3    Perrier, A.4    Bounameaux, H.5
  • 22
    • 0038380256 scopus 로고    scopus 로고
    • The epidemiology of venous thromboembolism
    • DOI 10.1161/01.CIR.0000078468.11849.66
    • White RH. The epidemiology of venous thromboembolism. Circulation 2003;107(23 Suppl 1):I4-8. (Pubitemid 41289265)
    • (2003) Circulation , vol.107 , Issue.SUPPL. 23
    • White, R.H.1
  • 23
    • 0025891903 scopus 로고
    • A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study
    • Anderson FA Jr, Wheeler HB, Goldberg RJ, Hosmer DW, Patwardhan NA, Jovanovic B, et al. A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study. Arch Intern Med 1991;151:933-8.
    • (1991) Arch Intern Med , vol.151 , pp. 933-938
    • Anderson Jr., F.A.1    Wheeler, H.B.2    Goldberg, R.J.3    Hosmer, D.W.4    Patwardhan, N.A.5    Jovanovic, B.6
  • 24
    • 84865728011 scopus 로고    scopus 로고
    • Systematic reviews of studies quantifying the accuracy of diagnostic tests and markers
    • Reitsma JB, Moons KG, Bossuyt PM, Linnet K. Systematic reviews of studies quantifying the accuracy of diagnostic tests and markers. Clin Chem 2012;58:1534-45.
    • (2012) Clin Chem , vol.58 , pp. 1534-1545
    • Reitsma, J.B.1    Moons, K.G.2    Bossuyt, P.M.3    Linnet, K.4
  • 26
    • 69449095395 scopus 로고    scopus 로고
    • Excluding venous thromboembolism using point of care D-dimer tests in outpatients: A diagnostic meta-analysis
    • Geersing GJ, Janssen KJ, Oudega R, Bax L, Hoes AW, Reitsma JB, et al. Excluding venous thromboembolism using point of care D-dimer tests in outpatients: a diagnostic meta-analysis. BMJ 2009;339:b2990.
    • (2009) BMJ , vol.339
    • Geersing, G.J.1    Janssen, K.J.2    Oudega, R.3    Bax, L.4    Hoes, A.W.5    Reitsma, J.B.6
  • 28
  • 29
    • 52149112349 scopus 로고    scopus 로고
    • Meta-analysis of diagnostic studies: A comparison of random intercept, normal-normal, and binomial-normal bivariate summary ROC approaches
    • Hamza TH, Reitsma JB, Stijnen T. Meta-analysis of diagnostic studies: a comparison of random intercept, normal-normal, and binomial-normal bivariate summary ROC approaches. Med Decis Making 2008;28:639-49.
    • (2008) Med Decis Making , vol.28 , pp. 639-649
    • Hamza, T.H.1    Reitsma, J.B.2    Stijnen, T.3
  • 32
    • 77951666347 scopus 로고    scopus 로고
    • Multicenter evaluation of a new quantitative highly sensitive D-dimer assay, the Hemosil D-dimer HS 500, in patients with clinically suspected venous thromboembolism
    • Legnani C, Cini M, Scarvelis D, Toulon P, Wu JR, Palareti G. Multicenter evaluation of a new quantitative highly sensitive D-dimer assay, the Hemosil D-dimer HS 500, in patients with clinically suspected venous thromboembolism. Thromb Res 2010;125:398-401.
    • (2010) Thromb Res , vol.125 , pp. 398-401
    • Legnani, C.1    Cini, M.2    Scarvelis, D.3    Toulon, P.4    Wu, J.R.5    Palareti, G.6
  • 33
    • 0038010699 scopus 로고    scopus 로고
    • A diagnostic strategy involving a quantitative latex D-dimer assay reliably excludes deep venous thrombosis
    • Bates SM, Kearon C, Crowther M, Linkins L, O'Donnell M, Douketis J, et al. A diagnostic strategy involving a quantitative latex D-dimer assay reliably excludes deep venous thrombosis. Ann Intern Med 2003;138:787-94.
    • (2003) Ann Intern Med , vol.138 , pp. 787-794
    • Bates, S.M.1    Kearon, C.2    Crowther, M.3    Linkins, L.4    O'Donnell, M.5    Douketis, J.6
  • 35
    • 30444431617 scopus 로고    scopus 로고
    • Effectiveness of managing suspected pulmonary embolism using an algorithm combining clinical probability, D-dimer testing, and computed tomography
    • DOI 10.1001/jama.295.2.172
    • Van Belle A, Buller HR, Huisman MV, Huisman PM, Kaasjager K, Kamphuisen PW, et al. Effectiveness of managing suspected pulmonary embolism using an algorithm combining clinical probability, D-dimer testing, and computed tomography. JAMA 2006;295:172-9. (Pubitemid 43076436)
    • (2006) Journal of the American Medical Association , vol.295 , Issue.2 , pp. 172-179
    • Huisman, M.V.1
  • 37
    • 72049087748 scopus 로고    scopus 로고
    • A computerized handheld decision-support system to improve pulmonary embolism diagnosis: A randomized trial
    • Roy PM, Durieux P, Gillaizeau F, Legall C, Armand-Perroux A, Martino L, et al. A computerized handheld decision-support system to improve pulmonary embolism diagnosis: a randomized trial. Ann Intern Med 2009;151:677-86.
    • (2009) Ann Intern Med , vol.151 , pp. 677-686
    • Roy, P.M.1    Durieux, P.2    Gillaizeau, F.3    Legall, C.4    Armand-Perroux, A.5    Martino, L.6
  • 43
    • 80054961278 scopus 로고    scopus 로고
    • The relationship between intervening hospitalizations and transitions between frailty states
    • Gill TM, Gahbauer EA, Han L, Allore HG. The relationship between intervening hospitalizations and transitions between frailty states. J Gerontol A Biol Sci Med Sci 2011;66:1238-43.
    • (2011) J Gerontol A Biol Sci Med Sci , vol.66 , pp. 1238-1243
    • Gill, T.M.1    Gahbauer, E.A.2    Han, L.3    Allore, H.G.4
  • 44
    • 53749097059 scopus 로고    scopus 로고
    • Serial 2-point ultrasonography plus D-dimer vs whole-leg color-coded Doppler ultrasonography for diagnosing suspected symptomatic deep vein thrombosis: A randomized controlled trial
    • Bernardi E, Camporese G, Buller HR, Siragusa S, Imberti D, Berchio A, et al. Serial 2-point ultrasonography plus D-dimer vs whole-leg color-coded Doppler ultrasonography for diagnosing suspected symptomatic deep vein thrombosis: a randomized controlled trial. JAMA 2008;300:1653-9.
    • (2008) JAMA , vol.300 , pp. 1653-1659
    • Bernardi, E.1    Camporese, G.2    Buller, H.R.3    Siragusa, S.4    Imberti, D.5    Berchio, A.6
  • 45
    • 84862260101 scopus 로고    scopus 로고
    • Prospective study of the incidence of contrast-induced nephropathy among patients evaluated for pulmonary embolism by contrast-enhanced computed tomography
    • Mitchell AM, Jones AE, Tumlin JA, Kline JA. Prospective study of the incidence of contrast-induced nephropathy among patients evaluated for pulmonary embolism by contrast-enhanced computed tomography. Acad Emerg Med 2012;19:618-25.
    • (2012) Acad Emerg Med , vol.19 , pp. 618-625
    • Mitchell, A.M.1    Jones, A.E.2    Tumlin, J.A.3    Kline, J.A.4
  • 47
    • 0032750034 scopus 로고    scopus 로고
    • Ruling out acute deep vein thrombosis by ELISA plasma D-dimer assay versus ultrasound in inpatients more than 70 years old
    • Le Blanche AF, Siguret V, Settegrana C, Bohus S, Le Masne de CE, Andreux JP, et al. Ruling out acute deep vein thrombosis by ELISA plasma D-dimer assay versus ultrasound in inpatients more than 70 years old. Angiology 1999;50:873-82.
    • (1999) Angiology , vol.50 , pp. 873-882
    • Le Blanche, A.F.1    Siguret, V.2    Settegrana, C.3    Bohus, S.4    Le Masne-De, C.E.5    Andreux, J.P.6
  • 48
    • 3042512341 scopus 로고    scopus 로고
    • D-dimer testing for deep venous thrombosis: A metaanalysis
    • DOI 10.1373/clinchem.2004.031765
    • Heim SW, Schectman JM, Siadaty MS, Philbrick JT. D-dimer testing for deep venous thrombosis: a metaanalysis. Clin Chem 2004;50:1136-47. (Pubitemid 38824223)
    • (2004) Clinical Chemistry , vol.50 , Issue.7 , pp. 1136-1147
    • Heim, S.W.1    Schectman, J.M.2    Siadaty, M.S.3    Philbrick, J.T.4
  • 50
    • 70350569884 scopus 로고    scopus 로고
    • Decision analysis to complete diagnostic research by closing the gap between test characteristics and cost-effectiveness
    • Schaafsma JD, van der GY, Rinkel GJ, Buskens E. Decision analysis to complete diagnostic research by closing the gap between test characteristics and cost-effectiveness. J Clin Epidemiol 2009;62:1248-52.
    • (2009) J Clin Epidemiol , vol.62 , pp. 1248-1252
    • Schaafsma, J.D.1    Van Der, G.Y.2    Rinkel, G.J.3    Buskens, E.4
  • 51
    • 84873038421 scopus 로고    scopus 로고
    • From accuracy to patient outcome and cost-effectiveness evaluations of diagnostic tests and biomarkers: An exemplary modelling study
    • Koffijberg H, van Zaane B, Moons KG. From accuracy to patient outcome and cost-effectiveness evaluations of diagnostic tests and biomarkers: an exemplary modelling study. BMC Med Res Methodol 2013;13:12.
    • (2013) BMC Med Res Methodol , vol.13 , pp. 12
    • Koffijberg, H.1    Van Zaane, B.2    Moons, K.G.3
  • 52
    • 67650089602 scopus 로고    scopus 로고
    • Prognosis and prognostic research: Application and impact of prognostic models in clinical practice
    • Moons KG, Altman DG, Vergouwe Y, Royston P. Prognosis and prognostic research: application and impact of prognostic models in clinical practice. BMJ 2009;338:b606.
    • (2009) BMJ , vol.338
    • Moons, K.G.1    Altman, D.G.2    Vergouwe, Y.3    Royston, P.4
  • 53
    • 33644855006 scopus 로고    scopus 로고
    • Translating clinical research into clinical practice: Impact of using prediction rules to make decisions
    • Reilly BM, Evans AT. Translating clinical research into clinical practice: impact of using prediction rules to make decisions. Ann Intern Med 2006;144:201-9. (Pubitemid 46780691)
    • (2006) Annals of Internal Medicine , vol.144 , Issue.3 , pp. 201-209
    • Reilly, B.M.1    Evans, A.T.2
  • 55
    • 79958120815 scopus 로고    scopus 로고
    • Performance of 4 clinical decision rules in the diagnostic management of acute pulmonary embolism: A prospective cohort study
    • Douma RA, Mos IC, Erkens PM, Nizet TA, Durian MF, Hovens MM, et al. Performance of 4 clinical decision rules in the diagnostic management of acute pulmonary embolism: a prospective cohort study. Ann Intern Med 2011;154:709-18.
    • (2011) Ann Intern Med , vol.154 , pp. 709-718
    • Douma, R.A.1    Mos, I.C.2    Erkens, P.M.3    Nizet, T.A.4    Durian, M.F.5    Hovens, M.M.6
  • 56
    • 22144442457 scopus 로고    scopus 로고
    • Ruling out deep venous thrombosis in primary care. A simple diagnostic algorithm including D-dimer testing
    • DOI 10.1160/TH04-12-0829
    • Oudega R, Moons KG, Hoes AW. Ruling out deep venous thrombosis in primary care. A simple diagnostic algorithm including D-dimer testing. Thromb Haemost 2005;94:200-5. (Pubitemid 40974725)
    • (2005) Thrombosis and Haemostasis , vol.94 , Issue.1 , pp. 200-205
    • Oudega, R.1    Moons, K.G.M.2    Hoes, A.W.3
  • 57
    • 0035902631 scopus 로고    scopus 로고
    • Excluding pulmonary embolism at the bedside without diagnostic imaging: Management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and D-dimer
    • Wells PS, Anderson DR, Rodger M, Stiell I, Dreyer JF, Barnes D, et al. Excluding pulmonary embolism at the bedside without diagnostic imaging: management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and d-dimer. Ann Intern Med 2001;135:98-107. (Pubitemid 32661192)
    • (2001) Annals of Internal Medicine , vol.135 , Issue.2 , pp. 98-107
    • Wells, P.S.1    Anderson, D.R.2    Rodger, M.3    Stiell, I.4    Dreyer, J.F.5    Barnes, D.6    Forgie, M.7    Kovacs, G.8    Ward, J.9    Kovacs, M.J.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.