Clinical usefulness of plasma chromogranin a in pancreatic neuroendocrine neoplasm

Journal of Korean Medical Science

Volumn 28, Issue 5, 2013, Pages 750-754

  Paik, Woo Hyun ^a   Ryu, Ji Kon ^a   Song, Byeong Jun ^a   Kim, Jaihwan ^a   Park, Joo Kyung ^a   Kim, Yong Tae ^a   Yoon, Yong Bum ^a  

^a Seoul National University College of Medicine   (South Korea)

Author keywords

Chromogranin A; Diagnosis; Pancreatic neoplasms; Pancreatic neuroendocrine neoplasm

Indexed keywords

CHROMOGRANIN A;

ADOLESCENT; ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BLOOD; DIAGNOSIS; FEMALE; HUMAN; MALE; MIDDLE AGED; NEUROENDOCRINE TUMOR; PANCREAS TUMOR; PANCREATIC NEUROENDOCRINE NEOPLASM; PATHOLOGY; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

CHROMOGRANIN A; DIAGNOSIS; PANCREATIC NEOPLASMS; PANCREATIC NEUROENDOCRINE NEOPLASM;

ADOLESCENT; ADULT; AGED; AREA UNDER CURVE; CHROMOGRANIN A; FEMALE; HUMANS; MALE; MIDDLE AGED; NEUROENDOCRINE TUMORS; PANCREATIC NEOPLASMS; RETROSPECTIVE STUDIES; ROC CURVE; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

EID: 84878535467     PISSN: 10118934     EISSN: 15986357     Source Type: Journal    
DOI: 10.3346/jkms.2013.28.5.750     Document Type: Article

References (26)

1. Mulkeen AL, Yoo PS, Cha C. Less common neoplasms of the pancreas. World J Gastroenterol 2006; 12: 3180-5.
2. Yao JC, Hassan M, Phan A, Dagohoy C, Leary C, Mares JE, Abdalla EK, Fleming JB, Vauthey JN, Rashid A, et al. One hundred years after "carcinoid": epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United States. J Clin Oncol 2008; 26: 3063-72.
3. Halfdanarson TR, Rubin J, Farnell MB, Grant CS, Petersen GM. Pancreatic endocrine neoplasms: epidemiology and prognosis of pancreatic endocrine tumors. Endocr Relat Cancer 2008; 15: 409-27.
4. Cheema A, Weber J, Strosberg JR. Incidental detection of pancreatic neuroendocrine tumors: an analysis of incidence and outcomes. Ann Surg Oncol 2012; 19: 2932-6.
5. Furukawa T, Tsukamoto Y, Naitoh Y, Mitake M, Hirooka Y, Hayakawa T. Differential diagnosis of pancreatic diseases with an intraductal ultrasound system. Gastrointest Endosc 1994; 40: 213-9.
6. Sakamoto H, Kitano M, Kamata K, El-Masry M, Kudo M. Diagnosis of pancreatic tumors by endoscopic ultrasonography. World J Radiol 2010; 2: 122-34.
7. Eriksson B, Oberg K. Neuroendocrine tumours of the pancreas. Br J Surg 2000; 87: 129-31.
8. Milan SA, Yeo CJ. Neuroendocrine tumors of the pancreas. Curr Opin Oncol 2012; 24: 46-55.
9. Paik WH, Yoon YB, Lee SH, Park JK, Woo SM, Yang KY, Seo JK, Ryu JK, Kim YT. Pancreatic endocrine tumors: clinical manifestations and predictive factors associated with survival. Korean J Gastroenterol 2008; 52: 171-8.
10. Deftos LJ. Chromogranin A: its role in endocrine function and as an endocrine and neuroendocrine tumor marker. Endocr Rev 1991; 12: 181-7.
11. O'Connor DT, Deftos LJ. Secretion of chromogranin A by peptide-producing endocrine neoplasms. N Engl J Med 1986; 314: 1145-51.
12. Sobol RE, Memoli V, Deftos LJ. Hormone-negative, chromogranin Apositive endocrine tumors. N Engl J Med 1989; 320: 444-7.
13. Nobels FR, Kwekkeboom DJ, Coopmans W, Schoenmakers CH, Lindemans J, De Herder WW, Krenning EP, Bouillon R, Lamberts SW. Chromogranin A as serum marker for neuroendocrine neoplasia: comparison with neuron-specific enolase and the alpha-subunit of glycoprotein hormones. J Clin Endocrinol Metab 1997; 82: 2622-8.
14. Zatelli MC, Torta M, Leon A, Ambrosio MR, Gion M, Tomassetti P, De Braud F, Delle Fave G, Dogliotti L, degli Uberti EC. Chromogranin A as a marker of neuroendocrine neoplasia: an Italian Multicenter Study. Endocr Relat Cancer 2007; 14: 473-82.
15. Baudin E, Bidart JM, Bachelot A, Ducreux M, Elias D, Ruffié P, Schlumberger M. Impact of chromogranin A measurement in the work-up of neuroendocrine tumors. Ann Oncol 2001; 12: S79-82.
16. Rindi G, KlÖppel G, Alhman H, Caplin M, Couvelard A, de Herder WW, Erikssson B, Falchetti A, Falconi M, Komminoth P, et al. TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system. Virchows Arch 2006; 449: 395-401.
17. Campana D, Nori F, Piscitelli L, Morselli-Labate AM, Pezzilli R, Corinaldesi R, Tomassetti P. Chromogranin A: is it a useful marker of neuroendocrine tumors? J Clin Oncol 2007; 25: 1967-73.
18. Ferolla P, Faggiano A, Mansueto G, Avenia N, Cantelmi MG, Giovenali P, Del Basso De Caro ML, Milone F, Scarpelli G, Masone S, et al. The biological characterization of neuroendocrine tumors: the role of neuroendocrine markers. J Endocrinol Invest 2008; 31: 277-86.
19. Stivanello M, Berruti A, Torta M, Termine A, Tampellini M, Gorzegno G, Angeli A, Dogliotti L. Circulating chromogranin A in the assessment of patients with neuroendocrine tumours: a single institution experience. Ann Oncol 2001; 12: S73-7.
20. Tomassetti P, Migliori M, Simoni P, Casadei R, De Iasio R, Corinaldesi R, Gullo L. Diagnostic value of plasma chromogranin A in neuroendocrine tumours. Eur J Gastroenterol Hepatol 2001; 13: 55-8.
21. Syversen U, Ramstad H, Gamme K, Qvigstad G, Falkmer S, Waldum HL. Clinical significance of elevated serum chromogranin A levels. Scand J Gastroenterol 2004; 39: 969-73.
22. Nobels FR, Kwekkeboom DJ, Bouillon R, Lamberts SW. Chromogranin A: its clinical value as marker of neuroendocrine tumours. Eur J Clin Invest 1998; 28: 431-40.
23. Peracchi M, Conte D, Gebbia C, Penati C, Pizzinelli S, Arosio M, Corbetta S, Spada A. Plasma chromogranin A in patients with sporadic gastro- entero-pancreatic neuroendocrine tumors or multiple endocrine neoplasia type 1. Eur J Endocrinol 2003; 148: 39-43.
24. Tomassetti P, Campana D, Piscitelli L, Casadei R, Santini D, Nori F, Morselli- Labate AM, Pezzilli R, Corinaldesi R. Endocrine pancreatic tumors: factors correlated with survival. Ann Oncol 2005; 16: 1806-10.
25. Panzuto F, Boninsegna L, Fazio N, Campana D, Pia Brizzi M, Capurso G, Scarpa A, De Braud F, Dogliotti L, Tomassetti P, et al. Metastatic and locally advanced pancreatic endocrine carcinomas: analysis of factors associated with disease progression. J Clin Oncol 2011; 29: 2372-7.
26. Hirschowitz BI, Worthington J, Mohnen J, Haber M. Chromogranin A in patients with acid hypersecretion and/or hypergastrinaemia. AlimentPharmacol Ther 2007; 26: 869-78.