Numerical 3D modeling of heat transfer in human tissues for microwave radiometry monitoring of brown fat metabolism

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 8584, Issue , 2013, Pages

  Rodrigues, Dario B ^a,b   Maccarini, Paolo F ^a   Salahi, Sara ^c   Colebeck, Erin ^d   Topsakal, Erdem ^d   Pereira, Pedro J S ^b,e   Limão Vieira, Paulo ^b   Stauffer, Paul R ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSIDADE NOVA DE LISBOA   (Portugal)

^c ANSYS INC   (United States)

^d MISSISSIPPI STATE UNIVERSITY   (United States)

^e INSTITUTO SUPERIOR DE ENGENHARIA DE LISBOA   (Portugal)

Author keywords

3D multiphysics modeling; Brown fat metabolism; log spiral antenna; microwave radiometry; noninvasive monitoring

Indexed keywords

FAT METABOLISM; LOG SPIRAL ANTENNAS; MICROWAVE RADIOMETRY; MULTI-PHYSICS MODELING; NON-INVASIVE MONITORING;

FREQUENCY BANDS; IMAGING TECHNIQUES; MICROWAVE DEVICES; MICROWAVES; MUSCLE; OPTIMIZATION; PHYSIOLOGY; RADIOMETRY; SPIRAL ANTENNAS; THREE DIMENSIONAL; THREE DIMENSIONAL COMPUTER GRAPHICS;

METABOLISM;

EID: 84878524598     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.2004931     Document Type: Conference Paper

References (42)

1. P. Hossain, B. Kawar, and M. El Nahas, " Obesity and diabetes in the developing world - a growing challenge," N Engl J Med, 356( 3), 213-5 ( 2007).
2. H. H. Hu, T. G. Perkins, J. M. Chia et al., " Characterization of human brown adipose tissue by chemical-shift water-fat MRI," AJR. American journal of roentgenology, 200( 1), ( 2013).
3. B. Cannon, and J. Nedergaard, " Brown adipose tissue: function and physiological significance," Physiol Rev, 84( 1), 277-359 ( 2004).
4. A. M. Cypess, S. Lehman, G. Williams et al., " Identification and importance of brown adipose tissue in adult humans," N Engl J Med, 360( 15), 1509-17 ( 2009).
5. K. A. Virtanen, M. E. Lidell, J. Orava et al., " Functional brown adipose tissue in healthy adults," N Engl J Med, 360( 15), 1518-25 ( 2009).
6. O. Muzik, T. J. Mangner, and J. G. Granneman, "Assessment of oxidative metabolism in brown fat using PET imaging ," Frontiers in endocrinology, 3, ( 2012).
7. E. Lunati, P. Marzola, E. Nicolato et al., " In vivo quantitative lipidic map of brown adipose tissue by chemical shift imaging at 4.7 tesla," Journal of Lipid Research, 40( 8), ( 1999).
8. N. J. Rothwell, and M. J. Stock, " A role for brown adipose tissue in diet-induced thermogenesis," Nature, 281( 5726), 31-5 ( 1979).
9. P. Lee, K. K. Y. Ho, and J. R. Greenfield, " Hot fat in a cool man: infrared thermography and brown adipose tissue," Diabetes Obesity & Metabolism, 13( 1), 92-93 ( 2011).
10. K. L. Carr, " Microwave Radiometry - Its Importance to the Detection of Cancer," IEEE Transactions on Microwave Theory and Techniques, 37( 12), 1862-1869 ( 1989).
11. F. Bardati, and S. Iudicello, " Modeling the visibility of breast malignancy by a microwave radiometer," IEEE Trans Biomed Eng, 55( 1), 214-21 ( 2008).
12. J. W. Hand, G. M. J. Van Leeuwen, S. Mizushina et al., " Monitoring of deep brain temperature in infants using multi-frequency microwave radiometry and thermal modelling," Physics in Medicine and Biology, 46( 7), ( 2001).
13. P. Stauffer, S. Salahi, D. Rodrigues et al., [Stable microwave radiometry system for long term monitoring of deep tissue temperature ] SPIE, San Jose CA, USA(2013).
14. S. Jacobsen, and P. R. Stauffer, " Can we settle with single-band radiometric temperature monitoring during hyperthermia treatment of chestwall recurrence of breast cancer using a dual-mode transceiving applicator?," Physics in Medicine & Biology, 52( 4), 911-28 ( 2007).
15. L. Dubois, J. P. Sozanski, V. Tessier et al., " Temperature control and thermal dosimetry by microwave radiometry in hyperthermia," IEEE Transactions on Microwave Theory and Techniques, 44( 10, pt.2), 1755-61 ( 1996).
16. K. Arunachalam, P. Maccarini, V. De Luca et al., " Modeling the detectability of vesicoureteral reflux using microwave radiometry," Phys. Med. Biol, 55( 18), 5417-35 ( 2010).
17. B. W. Snow, K. Arunachalam, V. De Luca et al., " Non-invasive vesicoureteral reflux detection: Heating risk studies for a new device," Journal of Pediatric Urology, 7( 6), ( 2011).
18. P. Stauffer, P. Maccarini, K. Arunachalam et al., [Microwave Radiometry for Non-Invasive Detection of Vesicoureteral Reflux (VUR) Following Bladder Warming ] SPIE Press, Bellingham WA, ( 2011 PMCID:3409575).
19. W. D. v. M. Lichtenbelt, J. W. Vanhommerig, N. M. Smulders et al., " Cold-Activated Brown Adipose Tissue in Healthy Men," New England Journal of Medicine, 360( 15), 1500-1508 ( 2009).
20. J. Nedergaard, T. Bengtsson, and B. Cannon, " Unexpected evidence for active brown adipose tissue in adult humans," American Journal of Physiology-Endocrinology and Metabolism, 293( 2), E444-E452 ( 2007).
21. M. Nechad, J. Nedergaard, and B. Cannon, " Noradrenergic stimulation of mitochondriogenesis in brown adipocytes differentiating in culture" American Journal of Physiology, 253( 6), C889-C894 ( 1987).
22. K. Arunachalam, P. Maccarini, V. De Luca et al., " Detection of vesicoureteral reflux using microwave radiometry-system characterization with tissue phantoms," IEEE Trans Biomed Eng, 58( 6), 1629-36 ( 2011).
23. Y. Birkelund, O. Klemetsen, S. K. Jacobsen et al., " Vesicoureteral reflux in children: a phantom study of microwave heating and radiometric thermometry of pediatric bladder," IEEE Trans Biomed Eng, 58( 11), 3269-78 ( 2011).
24. C. Balanis, [Antenna Theory: Analysis and Design ] John Wiley & Sons, Inc., Hoboken, New Jersey( 2005).
25. J. Thaysen, K. Jakobsen, and J. Appel-Hansen, " A logarithmic spiral antenna for 0.4 to 3.8 GHz," Applied Microwave & Wireless, ( 2001).
26. J. Dyson, " The Equiangular Spiral Antenna," IRE Transactions on Antennas Propagation, AP-7, 181-187 ( 1959).
27. P. Hasgall, E. Neufeld, M. Gosselin et al., [IT'IS Database for thermal and electromagnetic parameters of biological tissues], www.itis.ethz.ch/database (2011).
28. C. Gabriel, [Compilation of the dielectric properties of body tissues at RF and microwave frequencies ], Texas (USA)( 1996).
29. E. TopSakal, E. Colebeck, D. Rodrigues et al. , "Brown and white fat dielectric properties in rats," Physics in Medicine and Biology, Under Review, ( 2013).
30. A. Takata, L. Zaneveld, and W. Richter, [Laser-induced thermal damage in skin] USAF School Aerospace Medicine, Brooks AFB, TX( 1977).
31. V. A. Dubinskaya, L. S. Eng, L. B. Rebrow et al., " Comparative study of the state of water in various human tissues," Bulletin of Experimental Biology and Medicine, 144( 3), ( 2007).
32. C. A. Balanis, [Advanced Engineering Electromagnetics ] Wiley, New York( 1989).
33. D. M. Pozar, [Microwave Engineering ] John Wiley & sons, Inc., New York( 1998).
34. E. H. Wissler, " Pennes' 1948 paper revisited," Journal of Applied Physiology, 85, 36-42 ( 1998).
35. H. H. Pennes, " Analysis of tissue and arterial blood temperatures in the resting human forearm," Journal of Applied Physiology, 1( 2), 93-122 ( 1948).
36. C. Song, I. Choi, B. Nah et al., [Microvasculature and perfusion in normal tissues and tumors ] Springer-Verlag, Berlin, New York( 1995).
37. J. Fan, and L. Wang, " Analytical theory of bioheat transport," Journal of Applied Physics, 109( 10), ( 2011).
38. A. M. Cypess, S. Lehman, G. Williams et al., " Identification and Importance of Brown Adipose Tissue in Adult Humans," New England Journal of Medicine, 360( 15), 1509-1517 ( 2009).
39. V. Vuksanovic, L. W. Sheppard, and A. Stefanovska, " Nonlinear relationship between level of blood flow and skin temperature for different dynamics of temperature change," Biophysical Journal, 94( 10), L78-L80 ( 2008).
40. N. J. LaSorte, W. J. Barnes, H. H. Refai et al., "Characterization of the Electromagnetic Environment in a Hospital and Propagation Study ," Emc 2009: Ieee International Symposium on Electromagnetic Compatibility, Technical Paper, 135-140 ( 2009).
41. O. Klemetsen, Y. Birkelund, S. K. Jacobsen et al., " Design of Medical Radiometer Front-End for Improved Performance," Prog Electromagn Res B Pier B, 27, 289-306 ( 2011).
42. P. Stauffer, P. Maccarini, K. Arunachalam et al., [Microwave Radiometry for Non-Invasive Detection of Vesicoureteral Reflux (VUR) Following Bladder Warming ] SPIE Press, Bellingham WA, ( 2011).