Differences in morphology of fibrin clots induced with thrombin and ferric ions and its pathophysiological consequences

Heart Lung and Circulation

Volumn 22, Issue 6, 2013, Pages 447-449

  Pretorius, E ^a   Lipinski, B ^b  

^a UNIVERSITY OF PRETORIA   (South Africa)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Ferric iron; Fibrin; Scanning electron microscopy

Indexed keywords

FERRIC ION; FIBRIN; THROMBIN;

ARTICLE; BLOOD CLOTTING; CEREBROVASCULAR ACCIDENT; DIABETES MELLITUS; FIBRIN CLOT; FIBRINOLYTIC THERAPY; HUMAN; IRON OVERLOAD; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN STRUCTURE; SCANNING ELECTRON MICROSCOPY;

BLOOD COAGULATION; DIABETES MELLITUS; FEMALE; FERRIC COMPOUNDS; FIBRIN; HUMANS; IRON CHELATING AGENTS; IRON OVERLOAD; MALE; STROKE; THROMBIN; THROMBOSIS;

EID: 84878514911     PISSN: 14439506     EISSN: 14442892     Source Type: Journal    
DOI: 10.1016/j.hlc.2012.10.010     Document Type: Article

References (9)

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7. Pretorius E., Swanepoel A.C., Oberholzer H.M., van der Spuy W.J., Duim W., Wessels P.F. A descriptive investigation of the ultrastructure of fibrin networks in thrombo-embolic ischemic stroke. J Thromb Thrombolysis 2011, 31:507-513.
8. Lipinski B., Pretorius E. Novel pathway of iron-induced blood coagulation: implications for diabetes mellitus and its complications. Pol Arch Med Wewn 2012, 122:115-122.
9. Pretorius E, Bester J, Vermeulen N, Lipinski B. Oxidation inhibits iron-induced blood coagulation. Curr Drug Targets; in press.