Detection of Mixed Infection from Bacterial Whole Genome Sequence Data Allows Assessment of Its Role in Clostridium difficile Transmission

PLoS Computational Biology

Volumn 9, Issue 5, 2013, Pages

  Eyre, David W ^a,b   Cule, Madeleine L ^b,c   Griffiths, David ^a,c   Crook, Derrick W ^a,c   Peto, Tim E A ^a,c   Walker, A Sarah ^a,c,d   Wilson, Daniel J ^a,e  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d MEDICAL RESEARCH COUNCIL   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CLOSTRIDIUM; GENES; HOSPITALS; MAXIMUM LIKELIHOOD; STOCHASTIC MODELS;

CLOSTRIDIUM DIFFICILE; GENETIC RELATIONSHIPS; GENOME SEQUENCE DATA; HAPLOTYPES; HIGH-PRECISION; INFECTIOUS DISEASE OUTBREAKS; MIXED INFECTIONS; SEQUENCE DATA; WHOLE GENOME SEQUENCES; WHOLE GENOME SEQUENCING;

STOCHASTIC SYSTEMS;

ALGORITHM; ARTICLE; BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIAL TRANSMISSION; BACTERIUM COLONY; BACTERIUM ISOLATE; CALIBRATION; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE INFECTION; COMPUTER ANALYSIS; CONTROLLED STUDY; GENETIC DATABASE; GENETIC VARIABILITY; HAPLOTYPE; HOSPITAL INFECTION; HUMAN; IN VITRO STUDY; MAJOR CLINICAL STUDY; MAXIMUM LIKELIHOOD METHOD; MIXED INFECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; WARD;

BACTERIA (MICROORGANISMS); CLOSTRIDIUM DIFFICILE;

EID: 84878500216     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003059     Document Type: Article

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