-
1
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
ENCODE Consortium
-
ENCODE Consortium (2012) An integrated encyclopedia of DNA elements in the human genome. Nature 489: 57-74.
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
-
2
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff L, Sethupathy P, Junkins H, Ramos E, Mehta J, et al. (2009) Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proceedings of the National Academy of Sciences of the United States of America 106: 9362-9367.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.1
Sethupathy, P.2
Junkins, H.3
Ramos, E.4
Mehta, J.5
-
3
-
-
0035400051
-
Genetical genomics: the added value from segregation
-
Jansen R, Nap J, (2001) Genetical genomics: the added value from segregation. Trends in Genetics 17: 388-391.
-
(2001)
Trends in Genetics
, vol.17
, pp. 388-391
-
-
Jansen, R.1
Nap, J.2
-
4
-
-
84857192201
-
Cellular genomics for complex traits
-
Dermitzakis E, (2012) Cellular genomics for complex traits. Nature Reviews Genetics 13: 215-220.
-
(2012)
Nature Reviews Genetics
, vol.13
, pp. 215-220
-
-
Dermitzakis, E.1
-
5
-
-
47249142778
-
Revealing the architecture of gene regulation: the promise of eQTL studies
-
Gilad Y, Rifkin S, Pritchard J, (2008) Revealing the architecture of gene regulation: the promise of eQTL studies. Trends in Genetics 24: 408-415.
-
(2008)
Trends in Genetics
, vol.24
, pp. 408-415
-
-
Gilad, Y.1
Rifkin, S.2
Pritchard, J.3
-
6
-
-
77952367694
-
Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations
-
doi:10.1371/journal.pgen.1000895
-
Nica A, Montgomery S, Dimas A, Stranger B, Beazley C, et al. (2010) Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations. PLoS Genet 6 (4):: e1000895 doi:10.1371/journal.pgen.1000895.
-
(2010)
PLoS Genet
, vol.6
, Issue.4
-
-
Nica, A.1
Montgomery, S.2
Dimas, A.3
Stranger, B.4
Beazley, C.5
-
7
-
-
77951439152
-
Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS
-
doi:10.1371/journal.pgen.1000888
-
Nicolae D, Gamazon E, Zhang W, Duan S, Dolan M, et al. (2010) Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS. PLoS Genet 6 (4):: e1000888 doi:10.1371/journal.pgen.1000888.
-
(2010)
PLoS Genet
, vol.6
, Issue.4
-
-
Nicolae, D.1
Gamazon, E.2
Zhang, W.3
Duan, S.4
Dolan, M.5
-
8
-
-
0037177625
-
Genetic dissection of transcriptional regulation in budding yeast
-
Brem R, Yvert Gl, Clinton R, Kruglyak L, (2002) Genetic dissection of transcriptional regulation in budding yeast. Science (New York, NY) 296: 752-755.
-
(2002)
Science (New York, NY)
, vol.296
, pp. 752-755
-
-
Brem, R.1
Yvert, G.2
Clinton, R.3
Kruglyak, L.4
-
9
-
-
0037456823
-
Genetics of gene expression surveyed in maize, mouse and man
-
Schadt E, Monks S, Drake T, Lusis A, Che N, et al. (2003) Genetics of gene expression surveyed in maize, mouse and man. Nature 422: 297-302.
-
(2003)
Nature
, vol.422
, pp. 297-302
-
-
Schadt, E.1
Monks, S.2
Drake, T.3
Lusis, A.4
Che, N.5
-
10
-
-
0037370311
-
Natural variation in human gene expression assessed in lymphoblastoid cells
-
Cheung V, Conlin L, Weber T, Arcaro M, Jen K-Y, et al. (2003) Natural variation in human gene expression assessed in lymphoblastoid cells. Nature Genetics 33: 422-425.
-
(2003)
Nature Genetics
, vol.33
, pp. 422-425
-
-
Cheung, V.1
Conlin, L.2
Weber, T.3
Arcaro, M.4
Jen, K.-Y.5
-
11
-
-
8844244726
-
Genetic inheritance of gene expression in human cell lines
-
Monks SA, Leonardson A, Zhu H, Cundiff P, Pietrusiak P, (2004) Genetic inheritance of gene expression in human cell lines. Am J Hum Genet 75: 1095-105.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 1095-1105
-
-
Monks, S.A.1
Leonardson, A.2
Zhu, H.3
Cundiff, P.4
Pietrusiak, P.5
-
12
-
-
4043128071
-
Genetic analysis of genome-wide variation in human gene expression
-
Morley M, Molony C, Weber T, Devlin J, Ewens K, et al. (2004) Genetic analysis of genome-wide variation in human gene expression. Nature 430: 743-747.
-
(2004)
Nature
, vol.430
, pp. 743-747
-
-
Morley, M.1
Molony, C.2
Weber, T.3
Devlin, J.4
Ewens, K.5
-
13
-
-
79952263851
-
Single-tissue and cross-tissue heritability of gene expression via identity-by-descent in related or unrelated individuals
-
doi:10.1371/journal.pgen.1001317
-
Price A, Helgason A, Thorleifsson G, McCarroll S, Kong A, et al. (2011) Single-tissue and cross-tissue heritability of gene expression via identity-by-descent in related or unrelated individuals. PLoS Genet 7 (2):: e1001317 doi:10.1371/journal.pgen.1001317.
-
(2011)
PLoS Genet
, vol.7
, Issue.2
-
-
Price, A.1
Helgason, A.2
Thorleifsson, G.3
McCarroll, S.4
Kong, A.5
-
14
-
-
84857856577
-
Genetic control of gene expression in whole blood and lymphoblastoid cell lines is largely independent
-
Powell J, Henders A, McRae A, Wright M, Martin N, et al. (2012) Genetic control of gene expression in whole blood and lymphoblastoid cell lines is largely independent. Genome Research 22: 456-466.
-
(2012)
Genome Research
, vol.22
, pp. 456-466
-
-
Powell, J.1
Henders, A.2
McRae, A.3
Wright, M.4
Martin, N.5
-
15
-
-
34548719076
-
Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes
-
Goring HH, Curran J, Johnson M, Dyer T, Charlesworth J, et al. (2007) Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes. Nature Genetics 39: 1208-1216.
-
(2007)
Nature Genetics
, vol.39
, pp. 1208-1216
-
-
Goring, H.H.1
Curran, J.2
Johnson, M.3
Dyer, T.4
Charlesworth, J.5
-
16
-
-
34548805282
-
A genome-wide association study of global gene expression
-
Dixon A, Liang L, Moffatt M, Chen W, Heath S, et al. (2007) A genome-wide association study of global gene expression. Nature Genetics 39: 1202-1207.
-
(2007)
Nature Genetics
, vol.39
, pp. 1202-1207
-
-
Dixon, A.1
Liang, L.2
Moffatt, M.3
Chen, W.4
Heath, S.5
-
17
-
-
41349095280
-
Genetics of gene expression and its effect on disease
-
Emilsson V, Thorleifsson G, Zhang B, Leonardson A, Zink F, et al. (2008) Genetics of gene expression and its effect on disease. Nature 452: 423-428.
-
(2008)
Nature
, vol.452
, pp. 423-428
-
-
Emilsson, V.1
Thorleifsson, G.2
Zhang, B.3
Leonardson, A.4
Zink, F.5
-
18
-
-
84866871814
-
Mapping cis- and trans-regulatory effects across multiple tissues in twins
-
Grundberg E, Small K, Hedman A, Nica A, Buil A, et al. (2012) Mapping cis- and trans-regulatory effects across multiple tissues in twins. Nat Genet 44: 1084-1089.
-
(2012)
Nat Genet
, vol.44
, pp. 1084-1089
-
-
Grundberg, E.1
Small, K.2
Hedman, A.3
Nica, A.4
Buil, A.5
-
19
-
-
23644434284
-
Genetic interactions between polymorphisms that affect gene expression in yeast
-
Brem R, Storey J, Whittle J, Kruglyak L, (2005) Genetic interactions between polymorphisms that affect gene expression in yeast. Nature 436: 701-703.
-
(2005)
Nature
, vol.436
, pp. 701-703
-
-
Brem, R.1
Storey, J.2
Whittle, J.3
Kruglyak, L.4
-
20
-
-
33750481513
-
Heritability and tissue specificity of expression quantitative trait loci
-
doi:10.1371/journal.pgen.0020172
-
Petretto E, Mangion J, Dickens N, Cook S, Kumaran M, et al. (2006) Heritability and tissue specificity of expression quantitative trait loci. PLoS Genet 2 (10):: e172 doi:10.1371/journal.pgen.0020172.
-
(2006)
PLoS Genet
, vol.2
, Issue.10
-
-
Petretto, E.1
Mangion, J.2
Dickens, N.3
Cook, S.4
Kumaran, M.5
-
21
-
-
77956637896
-
Genetics and beyond-the transcriptome of human monocytes and disease susceptibility
-
doi:10.1371/journal.pone.0010693
-
Zeller T, Wild P, Szymczak S, Rotival M, Schillert A, et al. (2010) Genetics and beyond-the transcriptome of human monocytes and disease susceptibility. PloS ONE 5 (5):: e10693 doi:10.1371/journal.pone.0010693.
-
(2010)
PloS ONE
, vol.5
, Issue.5
-
-
Zeller, T.1
Wild, P.2
Szymczak, S.3
Rotival, M.4
Schillert, A.5
-
22
-
-
33846978695
-
Relative impact of nucleotide and copy number variation on gene expression phenotypes
-
Stranger B, Forrest M, Dunning M, Ingle C, Beazley C, et al. (2007) Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science (New York, NY) 315: 848-853.
-
(2007)
Science (New York, NY)
, vol.315
, pp. 848-853
-
-
Stranger, B.1
Forrest, M.2
Dunning, M.3
Ingle, C.4
Beazley, C.5
-
24
-
-
84860596557
-
Patterns of cis regulatory variation in diverse human populations
-
doi:10.1371/journal.pgen.1002639
-
Stranger B, Montgomery S, Dimas A, Parts L, Stegle O, et al. (2012) Patterns of cis regulatory variation in diverse human populations. PLoS Genet 8: e1002639 doi:10.1371/journal.pgen.1002639.
-
(2012)
PLoS Genet
, vol.8
-
-
Stranger, B.1
Montgomery, S.2
Dimas, A.3
Parts, L.4
Stegle, O.5
-
25
-
-
27644482314
-
Mapping determinants of human gene expression by regional and genome-wide association
-
Cheung V, Spielman R, Ewens K, Weber T, Morley M, et al. (2005) Mapping determinants of human gene expression by regional and genome-wide association. Nature 437: 1365-1369.
-
(2005)
Nature
, vol.437
, pp. 1365-1369
-
-
Cheung, V.1
Spielman, R.2
Ewens, K.3
Weber, T.4
Morley, M.5
-
26
-
-
77950460661
-
Understanding mechanisms underlying human gene expression variation with RNA sequencing
-
Pickrell J, Marioni J, Pai A, Degner J, Engelhardt B, et al. (2010) Understanding mechanisms underlying human gene expression variation with RNA sequencing. Nature 464: 768-772.
-
(2010)
Nature
, vol.464
, pp. 768-772
-
-
Pickrell, J.1
Marioni, J.2
Pai, A.3
Degner, J.4
Engelhardt, B.5
-
27
-
-
55449112450
-
High-resolution mapping of expression-QTLs yields insight into human gene regulation
-
doi:10.1371/journal.pgen.1000214
-
Veyrieras J-B, Kudaravalli S, Kim S, Dermitzakis E, Gilad Y, et al. (2008) High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet 4 (10):: e1000214 doi:10.1371/journal.pgen.1000214.
-
(2008)
PLoS Genet
, vol.4
, Issue.10
-
-
Veyrieras, J.-B.1
Kudaravalli, S.2
Kim, S.3
Dermitzakis, E.4
Gilad, Y.5
-
28
-
-
69949176863
-
Common regulatory variation impacts gene expression in a cell type-dependent manner
-
Dimas A, Deutsch S, Stranger B, Montgomery S, Borel C, et al. (2009) Common regulatory variation impacts gene expression in a cell type-dependent manner. Science (New York, NY) 325: 1246-1250.
-
(2009)
Science (New York, NY)
, vol.325
, pp. 1246-1250
-
-
Dimas, A.1
Deutsch, S.2
Stranger, B.3
Montgomery, S.4
Borel, C.5
-
29
-
-
84856321864
-
Dissecting the regulatory architecture of gene expression QTLs
-
Gaffney D, Veyrieras J-B, Degner J, Pique-Regi R, Pai A, et al. (2012) Dissecting the regulatory architecture of gene expression QTLs. Genome Biology 13: R7.
-
(2012)
Genome Biology
, vol.13
-
-
Gaffney, D.1
Veyrieras, J.-B.2
Degner, J.3
Pique-Regi, R.4
Pai, A.5
-
30
-
-
84857131934
-
Exon-specific QTLs skew the inferred distribution of expression QTLs detected using gene expression array data
-
doi:10.1371/journal.pone.0030629
-
Veyrieras J-B, Gaffney D, Pickrell J, Gilad Y, Stephens M, et al. (2012) Exon-specific QTLs skew the inferred distribution of expression QTLs detected using gene expression array data. PloS ONE 7: e30629 doi:10.1371/journal.pone.0030629.
-
(2012)
PloS ONE
, vol.7
-
-
Veyrieras, J.-B.1
Gaffney, D.2
Pickrell, J.3
Gilad, Y.4
Stephens, M.5
-
31
-
-
79953303842
-
RNA sequencing reveals the role of splicing polymorphisms in regulating human gene expression
-
Lalonde E, Ha K, Wang Z, Bemmo A, Kleinman C, et al. (2011) RNA sequencing reveals the role of splicing polymorphisms in regulating human gene expression. Genome Research 21: 545-554.
-
(2011)
Genome Research
, vol.21
, pp. 545-554
-
-
Lalonde, E.1
Ha, K.2
Wang, Z.3
Bemmo, A.4
Kleinman, C.5
-
32
-
-
58149159713
-
Effects of cis and trans genetic ancestry on gene expression in African Americans
-
doi:10.1371/journal.pgen.1000294
-
Price A, Patterson N, Hancks D, Myers S, Reich D, et al. (2008) Effects of cis and trans genetic ancestry on gene expression in African Americans. PLoS Genet 4: e1000294 doi:10.1371/journal.pgen.1000294.
-
(2008)
PLoS Genet
, vol.4
-
-
Price, A.1
Patterson, N.2
Hancks, D.3
Myers, S.4
Reich, D.5
-
33
-
-
77957920003
-
Polymorphic cis- and trans-regulation of human gene expression
-
doi:10.1371/journal.pbio.1000480
-
Cheung V, Nayak R, Wang I, Elwyn S, Cousins S, et al. (2010) Polymorphic cis- and trans-regulation of human gene expression. PLoS Biol 8: e1000480 doi:10.1371/journal.pbio.1000480.
-
(2010)
PLoS Biol
, vol.8
-
-
Cheung, V.1
Nayak, R.2
Wang, I.3
Elwyn, S.4
Cousins, S.5
-
34
-
-
55449096399
-
Genetical genomics: spotlight on QTL hotspots
-
doi:10.1371/journal.pgen.1000232
-
Breitling R, Li Y, Tesson B, Fu J, Wu C, et al. (2008) Genetical genomics: spotlight on QTL hotspots. PLoS Genet 4: e1000232 doi:10.1371/journal.pgen.1000232.
-
(2008)
PLoS Genet
, vol.4
-
-
Breitling, R.1
Li, Y.2
Tesson, B.3
Fu, J.4
Wu, C.5
-
35
-
-
77955505742
-
A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies
-
doi:10.1371/journal.pcbi.1000770
-
Stegle O, Parts L, Durbin R, Winn J, (2010) A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies. PLoS Comp Biol 6: e1000770 doi:10.1371/journal.pcbi.1000770.
-
(2010)
PLoS Comp Biol
, vol.6
-
-
Stegle, O.1
Parts, L.2
Durbin, R.3
Winn, J.4
-
36
-
-
84860372128
-
The Brisbane Systems Genetics Study: genetical genomics meets complex trait genetics
-
doi:10.1371/journal.pone.0035430
-
Powell J, Henders A, McRae A, Caracella A, Smith S, et al. (2012) The Brisbane Systems Genetics Study: genetical genomics meets complex trait genetics. PloS ONE 7: e35430 doi:10.1371/journal.pone.0035430.
-
(2012)
PloS ONE
, vol.7
-
-
Powell, J.1
Henders, A.2
McRae, A.3
Caracella, A.4
Smith, S.5
-
37
-
-
80052322958
-
Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA
-
doi:10.1371/journal.pgen.1002197
-
Fehrmann R, Jansen R, Veldink J, Westra H-J, Arends D, et al. (2011) Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. PLoS Genet 7 (8):: e1002197 doi:10.1371/journal.pgen.1002197.
-
(2011)
PLoS Genet
, vol.7
, Issue.8
-
-
Fehrmann, R.1
Jansen, R.2
Veldink, J.3
Westra, H.-J.4
Arends, D.5
-
38
-
-
84855267424
-
Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans
-
doi:10.1371/journal.pgen.1002367
-
Rotival M, Zeller T, Wild P, Maouche S, Szymczak S, et al. (2011) Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans. PLoS Genet 7: e1002367 doi:10.1371/journal.pgen.1002367.
-
(2011)
PLoS Genet
, vol.7
-
-
Rotival, M.1
Zeller, T.2
Wild, P.3
Maouche, S.4
Szymczak, S.5
-
39
-
-
65249170333
-
Genetic analysis of radiation-induced changes in human gene expression
-
Smirnov D, Morley M, Shin E, Spielman R, Cheung V, (2009) Genetic analysis of radiation-induced changes in human gene expression. Nature 459: 587-591.
-
(2009)
Nature
, vol.459
, pp. 587-591
-
-
Smirnov, D.1
Morley, M.2
Shin, E.3
Spielman, R.4
Cheung, V.5
-
40
-
-
84867010006
-
c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells
-
Nie Z, Hu G, Wei G, Cui K, Yamane A, et al. (2012) c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells. Cell 151: 68-79.
-
(2012)
Cell
, vol.151
, pp. 68-79
-
-
Nie, Z.1
Hu, G.2
Wei, G.3
Cui, K.4
Yamane, A.5
-
41
-
-
84868010349
-
Revisiting global gene expression analysis
-
Loven J, Orlando D, Sigova A, Lin C, Rahl P, et al. (2012) Revisiting global gene expression analysis. Cell 151: 476-482.
-
(2012)
Cell
, vol.151
, pp. 476-482
-
-
Loven, J.1
Orlando, D.2
Sigova, A.3
Lin, C.4
Rahl, P.5
-
42
-
-
70350683774
-
Expression quantitative trait loci detected in cell lines are often present in primary tissues
-
Bullaughey K, Chavarria C, Coop G, Gilad Y, (2009) Expression quantitative trait loci detected in cell lines are often present in primary tissues. Human Molecular Genetics 18: 4296-4303.
-
(2009)
Human Molecular Genetics
, vol.18
, pp. 4296-4303
-
-
Bullaughey, K.1
Chavarria, C.2
Coop, G.3
Gilad, Y.4
-
43
-
-
57149114316
-
Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines
-
doi:10.1371/journal.pgen.1000287
-
Choy E, Yelensky R, Bonakdar S, Plenge R, Saxena R, et al. (2008) Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines. PLoS Genet 4: e1000287 doi:10.1371/journal.pgen.1000287.
-
(2008)
PLoS Genet
, vol.4
-
-
Choy, E.1
Yelensky, R.2
Bonakdar, S.3
Plenge, R.4
Saxena, R.5
-
44
-
-
51849156965
-
Extreme clonality in lymphoblastoid cell lines with implications for allele specific expression analyses
-
doi:10.1371/journal.pone.0002966
-
Plagnol V, Uz E, Wallace C, Stevens H, Clayton D, et al. (2008) Extreme clonality in lymphoblastoid cell lines with implications for allele specific expression analyses. PloS ONE 3: e2966 doi:10.1371/journal.pone.0002966.
-
(2008)
PloS ONE
, vol.3
-
-
Plagnol, V.1
Uz, E.2
Wallace, C.3
Stevens, H.4
Clayton, D.5
-
45
-
-
58149163446
-
Tissue-specific genetic control of splicing: implications for the study of complex traits
-
doi:10.1371/journal.pbio.1000001
-
Heinzen E, Ge D, Cronin K, Maia J, Shianna K, et al. (2008) Tissue-specific genetic control of splicing: implications for the study of complex traits. PLoS Biol 6: e1 doi:10.1371/journal.pbio.1000001.
-
(2008)
PLoS Biol
, vol.6
-
-
Heinzen, E.1
Ge, D.2
Cronin, K.3
Maia, J.4
Shianna, K.5
-
46
-
-
45149108420
-
Mapping the genetic architecture of gene expression in human liver
-
doi:10.1371/journal.pbio.0060107
-
Schadt E, Molony C, Chudin E, Hao K, Yang X, (2008) Mapping the genetic architecture of gene expression in human liver. PLoS Biol 6: e107 doi:10.1371/journal.pbio.0060107.
-
(2008)
PLoS Biol
, vol.6
-
-
Schadt, E.1
Molony, C.2
Chudin, E.3
Hao, K.4
Yang, X.5
-
47
-
-
70350724550
-
Population genomics in a disease targeted primary cell model
-
Grundberg E, Kwan T, Ge B, Lam K, Koka V, et al. (2009) Population genomics in a disease targeted primary cell model. Genome Research 19: 1942-1952.
-
(2009)
Genome Research
, vol.19
, pp. 1942-1952
-
-
Grundberg, E.1
Kwan, T.2
Ge, B.3
Lam, K.4
Koka, V.5
-
48
-
-
77953223693
-
Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain
-
doi:10.1371/journal.pgen.1000952
-
Gibbs J, van der Brug M, Hernandez D, Traynor B, Nalls M, et al. (2010) Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain. PLoS Genet 6 (5):: e1000952 doi:10.1371/journal.pgen.1000952.
-
(2010)
PLoS Genet
, vol.6
, Issue.5
-
-
Gibbs, J.1
van der Brug, M.2
Hernandez, D.3
Traynor, B.4
Nalls, M.5
-
49
-
-
84860317030
-
Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles
-
Fairfax B, Makino S, Radhakrishnan J, Plant K, Leslie S, et al. (2012) Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles. Nature Genetics 44: 502-510.
-
(2012)
Nature Genetics
, vol.44
, pp. 502-510
-
-
Fairfax, B.1
Makino, S.2
Radhakrishnan, J.3
Plant, K.4
Leslie, S.5
-
50
-
-
84857487802
-
Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression
-
doi:10.1371/journal.pgen.1002431
-
Fu J, Wolfs M, Deelen P, Westra H-J, Fehrmann R, et al. (2012) Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression. PLoS Genet 8 (1):: e1002431 doi:10.1371/journal.pgen.1002431.
-
(2012)
PLoS Genet
, vol.8
, Issue.1
-
-
Fu, J.1
Wolfs, M.2
Deelen, P.3
Westra, H.-J.4
Fehrmann, R.5
-
51
-
-
78649783848
-
Gene expression in skin and lymphoblastoid cells: Refined statistical method reveals extensive overlap in cis-eQTL signals
-
Ding J, Gudjonsson J, Liang L, Stuart P, Li Y, et al. (2010) Gene expression in skin and lymphoblastoid cells: Refined statistical method reveals extensive overlap in cis-eQTL signals. American Journal of Human Genetics 87: 779-789.
-
(2010)
American Journal of Human Genetics
, vol.87
, pp. 779-789
-
-
Ding, J.1
Gudjonsson, J.2
Liang, L.3
Stuart, P.4
Li, Y.5
-
52
-
-
79952256739
-
The architecture of gene regulatory variation across multiple human tissues: the MuTHER study
-
doi:10.1371/journal.pgen.1002003
-
Nica A, Parts L, Glass D, Nisbet J, Barrett A, et al. (2011) The architecture of gene regulatory variation across multiple human tissues: the MuTHER study. PLoS Genet 7 (2):: e1002003 doi:10.1371/journal.pgen.1002003.
-
(2011)
PLoS Genet
, vol.7
, Issue.2
-
-
Nica, A.1
Parts, L.2
Glass, D.3
Nisbet, J.4
Barrett, A.5
-
53
-
-
79959916375
-
A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort
-
Greenawalt D, Dobrin R, Chudin E, Hatoum I, Suver C, et al. (2011) A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort. Genome research 21: 1008-1016.
-
(2011)
Genome Research
, vol.21
, pp. 1008-1016
-
-
Greenawalt, D.1
Dobrin, R.2
Chudin, E.3
Hatoum, I.4
Suver, C.5
-
54
-
-
34547216747
-
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
-
Moffatt M, Kabesch M, Liang L, Dixon A, Strachan D, et al. (2007) Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 448: 470-473.
-
(2007)
Nature
, vol.448
, pp. 470-473
-
-
Moffatt, M.1
Kabesch, M.2
Liang, L.3
Dixon, A.4
Strachan, D.5
-
55
-
-
77649150074
-
The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress
-
Cantero-Recasens G, Fandos Cs, Rubio-Moscardo F, Valverde M, Vicente Rn, (2010) The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress. Human Molecular Genetics 19: 111-121.
-
(2010)
Human Molecular Genetics
, vol.19
, pp. 111-121
-
-
Cantero-Recasens, G.1
Fandos, C.2
Rubio-Moscardo, F.3
Valverde, M.4
Vicente, R.5
-
56
-
-
84891727891
-
Use of ENCODE and eQTL data to identify potential functional genetic variants at the 5q31 psoriatic arthritis susceptibility locus
-
Bluett J, Bowes J, Ho P, McHugh N, Barton A, (2013) Use of ENCODE and eQTL data to identify potential functional genetic variants at the 5q31 psoriatic arthritis susceptibility locus. The Lancet.
-
(2013)
The Lancet
-
-
Bluett, J.1
Bowes, J.2
Ho, P.3
McHugh, N.4
Barton, A.5
-
57
-
-
77955499945
-
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
-
Musunuru K, Strong A, Frank-Kamenetsky M, Lee N, Ahfeldt T, et al. (2010) From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature 466: 714-719.
-
(2010)
Nature
, vol.466
, pp. 714-719
-
-
Musunuru, K.1
Strong, A.2
Frank-Kamenetsky, M.3
Lee, N.4
Ahfeldt, T.5
-
58
-
-
84865268482
-
Expression QTL analysis of top loci from GWAS meta-analysis highlights additional schizophrenia candidate genes
-
de Jong S, van Eijk K, Zeegers D, Strengman E, Janson E, et al. (2012) Expression QTL analysis of top loci from GWAS meta-analysis highlights additional schizophrenia candidate genes. European Journal of Human Genetics 20: 1004-1008.
-
(2012)
European Journal of Human Genetics
, vol.20
, pp. 1004-1008
-
-
de Jong, S.1
van Eijk, K.2
Zeegers, D.3
Strengman, E.4
Janson, E.5
-
59
-
-
77950339092
-
Integrating pathway analysis and genetics of gene expression for genome-wide association studies
-
Zhong H, Yang X, Kaplan L, Molony C, Schadt E, (2010) Integrating pathway analysis and genetics of gene expression for genome-wide association studies. American Journal of Human Genetics 86: 581-591.
-
(2010)
American Journal of Human Genetics
, vol.86
, pp. 581-591
-
-
Zhong, H.1
Yang, X.2
Kaplan, L.3
Molony, C.4
Schadt, E.5
-
60
-
-
60349092402
-
Mapping complex disease traits with global gene expression
-
Cookson W, Liang L, Abecasis Ga, Moffatt M, Lathrop M, (2009) Mapping complex disease traits with global gene expression. Nature Reviews Genetics 10: 184-194.
-
(2009)
Nature Reviews Genetics
, vol.10
, pp. 184-194
-
-
Cookson, W.1
Liang, L.2
Abecasis, G.3
Moffatt, M.4
Lathrop, M.5
-
61
-
-
70249104647
-
Defining mechanisms that regulate RNA polymerase II transcription in vivo
-
Fuda N, Ardehali M, Lis J, (2009) Defining mechanisms that regulate RNA polymerase II transcription in vivo. Nature 461: 186-192.
-
(2009)
Nature
, vol.461
, pp. 186-192
-
-
Fuda, N.1
Ardehali, M.2
Lis, J.3
-
62
-
-
84857111200
-
DNaseI sensitivity QTLs are a major determinant of human expression variation
-
Degner J, Pai A, Pique-Regi R, Veyrieras J-B, Gaffney D, et al. (2012) DNaseI sensitivity QTLs are a major determinant of human expression variation. Nature 482: 390-394.
-
(2012)
Nature
, vol.482
, pp. 390-394
-
-
Degner, J.1
Pai, A.2
Pique-Regi, R.3
Veyrieras, J.-B.4
Gaffney, D.5
-
63
-
-
65549104157
-
Histone modifications at human enhancers reflect global cell-type-specific gene expression
-
Heintzman N, Hon G, Hawkins R, Kheradpour P, Stark A, et al. (2009) Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature 459: 108-112.
-
(2009)
Nature
, vol.459
, pp. 108-112
-
-
Heintzman, N.1
Hon, G.2
Hawkins, R.3
Kheradpour, P.4
Stark, A.5
-
64
-
-
79955583542
-
Mapping and analysis of chromatin state dynamics in nine human cell types
-
Ernst J, Kheradpour P, Mikkelsen T, Shoresh N, Ward L, et al. (2011) Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 473: 43-49.
-
(2011)
Nature
, vol.473
, pp. 43-49
-
-
Ernst, J.1
Kheradpour, P.2
Mikkelsen, T.3
Shoresh, N.4
Ward, L.5
-
65
-
-
77951610155
-
Genetic analysis of variation in transcription factor binding in yeast
-
Zheng W, Zhao H, Mancera E, Steinmetz L, Snyder M, (2010) Genetic analysis of variation in transcription factor binding in yeast. Nature 464: 1187-1191.
-
(2010)
Nature
, vol.464
, pp. 1187-1191
-
-
Zheng, W.1
Zhao, H.2
Mancera, E.3
Steinmetz, L.4
Snyder, M.5
-
66
-
-
77950833803
-
Variation in transcription factor binding among humans
-
Kasowski M, Grubert F, Heffelfinger C, Hariharan M, Asabere A, et al. (2010) Variation in transcription factor binding among humans. Science (New York, NY) 328: 232-235.
-
(2010)
Science (New York, NY)
, vol.328
, pp. 232-235
-
-
Kasowski, M.1
Grubert, F.2
Heffelfinger, C.3
Hariharan, M.4
Asabere, A.5
-
67
-
-
77950854479
-
Heritable individual-specific and allele-specific chromatin signatures in humans
-
McDaniell R, Lee B-K, Song L, Liu Z, Boyle A, et al. (2010) Heritable individual-specific and allele-specific chromatin signatures in humans. Science (New York, NY) 328: 235-239.
-
(2010)
Science (New York, NY)
, vol.328
, pp. 235-239
-
-
McDaniell, R.1
Lee, B.-K.2
Song, L.3
Liu, Z.4
Boyle, A.5
-
68
-
-
84859916280
-
Effects of sequence variation on differential allelic transcription factor occupancy and gene expression
-
Reddy T, Gertz J, Pauli F, Kucera K, Varley K, et al. (2012) Effects of sequence variation on differential allelic transcription factor occupancy and gene expression. Genome Research 22: 860-869.
-
(2012)
Genome Research
, vol.22
, pp. 860-869
-
-
Reddy, T.1
Gertz, J.2
Pauli, F.3
Kucera, K.4
Varley, K.5
-
69
-
-
34249725088
-
Allele-specific chromatin immunoprecipitation studies show genetic influence on chromatin state in human genome
-
doi:10.1371/journal.pgen.0030081
-
Kadota M, Yang H, Hu N, Wang C, Hu Y, et al. (2007) Allele-specific chromatin immunoprecipitation studies show genetic influence on chromatin state in human genome. PLoS Genet 3 (5):: e81 doi:10.1371/journal.pgen.0030081.
-
(2007)
PLoS Genet
, vol.3
, Issue.5
-
-
Kadota, M.1
Yang, H.2
Hu, N.3
Wang, C.4
Hu, Y.5
-
70
-
-
84859224243
-
Widespread site-dependent buffering of human regulatory polymorphism
-
doi:10.1371/journal.pgen.1002599
-
Maurano M, Wang H, Kutyavin T, Stamatoyannopoulos J, (2012) Widespread site-dependent buffering of human regulatory polymorphism. PLoS Genet 8 (3):: e1002599 doi:10.1371/journal.pgen.1002599.
-
(2012)
PLoS Genet
, vol.8
, Issue.3
-
-
Maurano, M.1
Wang, H.2
Kutyavin, T.3
Stamatoyannopoulos, J.4
-
71
-
-
46249117780
-
Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation
-
Kerkel K, Spadola A, Yuan E, Kosek J, Jiang L, et al. (2008) Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation. Nature Genetics 40: 904-908.
-
(2008)
Nature Genetics
, vol.40
, pp. 904-908
-
-
Kerkel, K.1
Spadola, A.2
Yuan, E.3
Kosek, J.4
Jiang, L.5
-
72
-
-
76249089640
-
Non-imprinted allele-specific DNA methylation on human autosomes
-
Zhang Y, Rohde C, Reinhardt R, Voelcker-Rehage C, Jeltsch A, (2009) Non-imprinted allele-specific DNA methylation on human autosomes. Genome Biology 10 (12):: R138.
-
(2009)
Genome Biology
, vol.10
, Issue.12
-
-
Zhang, Y.1
Rohde, C.2
Reinhardt, R.3
Voelcker-Rehage, C.4
Jeltsch, A.5
-
73
-
-
76049126281
-
Allelic skewing of DNA methylation is widespread across the genome
-
Schalkwyk L, Meaburn E, Smith R, Dempster E, Jeffries A, et al. (2010) Allelic skewing of DNA methylation is widespread across the genome. American Journal of Human Genetics 86: 196-212.
-
(2010)
American Journal of Human Genetics
, vol.86
, pp. 196-212
-
-
Schalkwyk, L.1
Meaburn, E.2
Smith, R.3
Dempster, E.4
Jeffries, A.5
-
74
-
-
77954238686
-
Allele-specific methylation is prevalent and is contributed by CpG-SNPs in the human genome
-
Shoemaker R, Deng J, Wang W, Zhang K, (2010) Allele-specific methylation is prevalent and is contributed by CpG-SNPs in the human genome. Genome Research 20: 883-889.
-
(2010)
Genome Research
, vol.20
, pp. 883-889
-
-
Shoemaker, R.1
Deng, J.2
Wang, W.3
Zhang, K.4
-
75
-
-
70350716441
-
Allele-specific DNA methylation in mouse strains is mainly determined by cis-acting sequences
-
Schilling E, El Chartouni C, Rehli M, (2009) Allele-specific DNA methylation in mouse strains is mainly determined by cis-acting sequences. Genome Research 19: 2028-2035.
-
(2009)
Genome Research
, vol.19
, pp. 2028-2035
-
-
Schilling, E.1
El Chartouni, C.2
Rehli, M.3
-
76
-
-
84857331867
-
Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome
-
Xie W, Barr C, Kim A, Yue F, Lee A, et al. (2012) Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome. Cell 148: 816-831.
-
(2012)
Cell
, vol.148
, pp. 816-831
-
-
Xie, W.1
Barr, C.2
Kim, A.3
Yue, F.4
Lee, A.5
-
77
-
-
79960688508
-
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
-
Bell J, Pai A, Pickrell J, Gaffney D, Pique-Regi R, et al. (2011) DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines. Genome Biology 12: R10.
-
(2011)
Genome Biology
, vol.12
-
-
Bell, J.1
Pai, A.2
Pickrell, J.3
Gaffney, D.4
Pique-Regi, R.5
-
78
-
-
77649204292
-
Genetic control of individual differences in gene-specific methylation in human brain
-
Zhang D, Cheng L, Badner J, Chen C, Chen Q, et al. (2010) Genetic control of individual differences in gene-specific methylation in human brain. American Journal of Human Genetics 86: 411-419.
-
(2010)
American Journal of Human Genetics
, vol.86
, pp. 411-419
-
-
Zhang, D.1
Cheng, L.2
Badner, J.3
Chen, C.4
Chen, Q.5
-
79
-
-
84865755978
-
The accessible chromatin landscape of the human genome
-
Thurman R, Rynes E, Humbert R, Vierstra J, Maurano M, et al. (2012) The accessible chromatin landscape of the human genome. Nature 489: 75-82.
-
(2012)
Nature
, vol.489
, pp. 75-82
-
-
Thurman, R.1
Rynes, E.2
Humbert, R.3
Vierstra, J.4
Maurano, M.5
-
81
-
-
79151484424
-
The study of eQTL variations by RNA-seq: from SNPs to phenotypes
-
Majewski J, Pastinen T, (2011) The study of eQTL variations by RNA-seq: from SNPs to phenotypes. Trends in Genetics 27: 72-79.
-
(2011)
Trends in Genetics
, vol.27
, pp. 72-79
-
-
Majewski, J.1
Pastinen, T.2
-
82
-
-
34547631469
-
Heritability of alternative splicing in the human genome
-
Kwan T, Benovoy D, Dias C, Gurd S, Serre D, et al. (2007) Heritability of alternative splicing in the human genome. Genome Research 17: 1210-1218.
-
(2007)
Genome Research
, vol.17
, pp. 1210-1218
-
-
Kwan, T.1
Benovoy, D.2
Dias, C.3
Gurd, S.4
Serre, D.5
-
83
-
-
38649090044
-
Genome-wide analysis of transcript isoform variation in humans
-
Kwan T, Benovoy D, Dias C, Gurd S, Provencher C, et al. (2008) Genome-wide analysis of transcript isoform variation in humans. Nature Genetics 40: 225-231.
-
(2008)
Nature Genetics
, vol.40
, pp. 225-231
-
-
Kwan, T.1
Benovoy, D.2
Dias, C.3
Gurd, S.4
Provencher, C.5
-
84
-
-
58849106627
-
Identification of common genetic variants that account for transcript isoform variation between human populations
-
Zhang W, Duan S, Bleibel W, Wisel S, Huang R, et al. (2009) Identification of common genetic variants that account for transcript isoform variation between human populations. Human Genetics 125: 81-93.
-
(2009)
Human Genetics
, vol.125
, pp. 81-93
-
-
Zhang, W.1
Duan, S.2
Bleibel, W.3
Wisel, S.4
Huang, R.5
-
85
-
-
63849281404
-
Common polymorphic transcript variation in human disease
-
Fraser H, Xie X, (2009) Common polymorphic transcript variation in human disease. Genome Research 19: 567-575.
-
(2009)
Genome Research
, vol.19
, pp. 567-575
-
-
Fraser, H.1
Xie, X.2
-
86
-
-
77950458649
-
Transcriptome genetics using second generation sequencing in a Caucasian population
-
Montgomery S, Sammeth M, Gutierrez-Arcelus M, Lach R, Ingle C, et al. (2010) Transcriptome genetics using second generation sequencing in a Caucasian population. Nature 464: 773-777.
-
(2010)
Nature
, vol.464
, pp. 773-777
-
-
Montgomery, S.1
Sammeth, M.2
Gutierrez-Arcelus, M.3
Lach, R.4
Ingle, C.5
-
87
-
-
84868154284
-
The contribution of RNA decay quantitative trait Loci to inter-individual variation in steady-state gene expression levels
-
doi:10.1371/journal.pgen.1003000
-
Pai A, Cain C, Mizrahi-Man O, De Leon S, Lewellen N, et al. (2012) The contribution of RNA decay quantitative trait Loci to inter-individual variation in steady-state gene expression levels. PLoS Genet 8 (10):: e1003000 doi:10.1371/journal.pgen.1003000.
-
(2012)
PLoS Genet
, vol.8
, Issue.10
-
-
Pai, A.1
Cain, C.2
Mizrahi-Man, O.3
de Leon, S.4
Lewellen, N.5
-
88
-
-
78651516723
-
Identification of cis- and trans-regulatory variation modulating microRNA expression levels in human fibroblasts
-
Borel C, Deutsch S, Letourneau A, Migliavacca E, Montgomery S, et al. (2011) Identification of cis- and trans-regulatory variation modulating microRNA expression levels in human fibroblasts. Genome Research 21: 68-73.
-
(2011)
Genome Research
, vol.21
, pp. 68-73
-
-
Borel, C.1
Deutsch, S.2
Letourneau, A.3
Migliavacca, E.4
Montgomery, S.5
-
89
-
-
84863641258
-
Extent, causes, and consequences of small RNA expression variation in human adipose tissue
-
doi:10.1371/journal.pgen.1002704
-
Parts L, Hedman ÖK, Keildson S, Knights A, Abreu-Goodger C, et al. (2012) Extent, causes, and consequences of small RNA expression variation in human adipose tissue. PLoS Genet 8 (5):: e1002704 doi:10.1371/journal.pgen.1002704.
-
(2012)
PLoS Genet
, vol.8
, Issue.5
-
-
Parts, L.1
Hedman, Ö.K.2
Keildson, S.3
Knights, A.4
Abreu-Goodger, C.5
-
90
-
-
84860604907
-
MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven
-
doi:10.1371/journal.pone.002733
-
Rantalainen M, Herrera B, Nicholson G, Bowden R, Wills Q, et al. (2011) MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven. PloS ONE 6 (11):: e27338 doi:10.1371/journal.pone.002733.
-
(2011)
PloS ONE
, vol.6
, Issue.11
-
-
Rantalainen, M.1
Herrera, B.2
Nicholson, G.3
Bowden, R.4
Wills, Q.5
-
91
-
-
84866167339
-
Genetics and regulatory impact of alternative polyadenylation in human B-lymphoblastoid cells
-
doi:10.1371/journal.pgen.1002882
-
Yoon O, Hsu T, Im J, Brem R, (2012) Genetics and regulatory impact of alternative polyadenylation in human B-lymphoblastoid cells. PLoS Genet 8 (8):: e1002882 doi:10.1371/journal.pgen.1002882.
-
(2012)
PLoS Genet
, vol.8
, Issue.8
-
-
Yoon, O.1
Hsu, T.2
Im, J.3
Brem, R.4
-
92
-
-
59249086642
-
Learning a prior on regulatory potential from eQTL data
-
doi:10.1371/journal.pgen.1000358:
-
Lee S-I, Dudley A, Drubin D, Silver P, Krogan N, et al. (2009) Learning a prior on regulatory potential from eQTL data. PLoS Genet 5 (1):: e1000358 doi: 10.1371/journal.pgen.1000358.
-
(2009)
PLoS Genet
, vol.5
, Issue.1
-
-
Lee, S.-I.1
Dudley, A.2
Drubin, D.3
Silver, P.4
Krogan, N.5
-
93
-
-
84868275675
-
Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS
-
Khan Z, Bloom J, Amini S, Singh M, Perlman D, et al. (2012) Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS. Molecular Systems Biology 8: 602.
-
(2012)
Molecular Systems Biology
, vol.8
, pp. 602
-
-
Khan, Z.1
Bloom, J.2
Amini, S.3
Singh, M.4
Perlman, D.5
-
94
-
-
84856387609
-
Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection
-
Barreiro L, Tailleux L, Pai A, Gicquel B, Marioni J, et al. (2012) Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection. Proceedings of the National Academy of Sciences of the United States of America 109: 1204-1209.
-
(2012)
Proceedings of the National Academy of Sciences of the United States of America
, vol.109
, pp. 1204-1209
-
-
Barreiro, L.1
Tailleux, L.2
Pai, A.3
Gicquel, B.4
Marioni, J.5
-
95
-
-
79960967243
-
Interactions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellular response phenotypes
-
doi:10.1371/journal.pgen.1002162
-
Maranville J, Luca F, Richards A, Wen X, Witonsky D, et al. (2011) Interactions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellular response phenotypes. PLoS Genet 7 (7):: e1002162 doi:10.1371/journal.pgen.1002162.
-
(2011)
PLoS Genet
, vol.7
, Issue.7
-
-
Maranville, J.1
Luca, F.2
Richards, A.3
Wen, X.4
Witonsky, D.5
-
96
-
-
84856573472
-
seeQTL: A searchable database for human eQTLs
-
Xia K, Shabalin A, Huang S, Madar V, Zhou Y-H, et al. (2012) seeQTL: A searchable database for human eQTLs. Bioinformatics (Oxford, England) 28: 451-452.
-
(2012)
Bioinformatics (Oxford, England)
, vol.28
, pp. 451-452
-
-
Xia, K.1
Shabalin, A.2
Huang, S.3
Madar, V.4
Zhou, Y.-H.5
-
97
-
-
34848914038
-
Capturing heterogeneity in gene expression studies by surrogate variable analysis
-
doi:10.1371/journal.pgen.0030161
-
Leek J, Storey J, (2007) Capturing heterogeneity in gene expression studies by surrogate variable analysis. PLoS Genet 3 (9):: e161 doi:10.1371/journal.pgen.0030161.
-
(2007)
PLoS Genet
, vol.3
, Issue.9
-
-
Leek, J.1
Storey, J.2
|