Phosphorylation of CDK9 at Ser175 Enhances HIV Transcription and Is a Marker of Activated P-TEFb in CD4+ T Lymphocytes

PLoS Pathogens

Volumn 9, Issue 5, 2013, Pages

  Mbonye, Uri R ^a   Gokulrangan, Giridharan ^a   Datt, Manish ^a   Dobrowolski, Curtis ^a   Cooper, Maxwell ^a   Chance, Mark R ^a   Karn, Jonathan ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 9; SMALL NUCLEAR RIBONUCLEOPROTEIN; T LYMPHOCYTE RECEPTOR; TRANSACTIVATOR PROTEIN; TRANSCRIPTION ELONGATION FACTOR; TRANSCRIPTION ELONGATION FACTOR P TEFB; UNCLASSIFIED DRUG;

ACETYLATION; ANTIBODY DETECTION; ARTICLE; AUTORADIOGRAPHY; CD4+ T LYMPHOCYTE; DENSITOMETRY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; LIQUID CHROMATOGRAPHY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY; TRANSACTIVATION; VIRUS TRANSCRIPTION; WESTERN BLOTTING;

BIOLOGICAL MARKERS; CD4-POSITIVE T-LYMPHOCYTES; CYCLIN T; CYCLIN-DEPENDENT KINASE 9; FEMALE; HIV; HIV INFECTIONS; HUMANS; MALE; MUTATION; NUCLEAR PROTEINS; PHOSPHORYLATION; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; PROTEIN BINDING; PROVIRUSES; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 84878491386     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003338     Document Type: Article

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