Identification of an influenza A H1N1/2009 virus with mutations in the matrix gene causing a negative result by a commercial molecular assay

Journal of Clinical Microbiology

Volumn 51, Issue 6, 2013, Pages 2006-2007

  Binnicker, Matthew J ^a   Baddour, Larry M ^a   Grys, Thomas E ^b   Espy, Mark J ^a   Hata, D Jane ^c   Wotton, Jason T ^d   Patel, Robin ^a  

^a MAYO CLINIC   (United States)

^b MAYO CLINIC   (United States)

^c MAYO CLINIC   (United States)

^d MINNESOTA DEPARTMENT OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CEFEPIME; LEVOFLOXACIN; OSELTAMIVIR; VANCOMYCIN;

2009 H1N1 INFLUENZA; ADENOVIRUS; ADULT; BACTERIUM CULTURE; CASE REPORT; CHILL; COUGHING; DYSPNEA; FEVER; GENE MUTATION; GENETIC VARIABILITY; HODGKIN DISEASE; HUMAN; HYPOXEMIA; INFLUENZA A; INFLUENZA VIRUS A; LEGIONELLA; LETTER; LUNG LAVAGE; NUCLEOTIDE SEQUENCE; PNEUMOCYSTIS JIROVECI; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESPIRATORY DISTRESS; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SEPTIC SHOCK; STREPTOCOCCUS PNEUMONIAE; VIRUS GENOME; VIRUS IDENTIFICATION;

ADULT; FALSE NEGATIVE REACTIONS; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MALE; MOLECULAR DIAGNOSTIC TECHNIQUES; MOLECULAR SEQUENCE DATA; MUTATION; RNA, VIRAL; SEQUENCE ANALYSIS, DNA; VIRAL MATRIX PROTEINS;

EID: 84878480833     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.00446-13     Document Type: Letter

References (5)

1. Dhiman N, Espy MJ, Irish C, Wright P, Smith TF, Pritt BS. 2010. Mutability in the matrix gene of novel influenza A H1N1 virus detected using a FRET probe-based real-time reverse transcriptase PCR assay. J. Clin. Microbiol. 48:677-679.
2. Zheng X, Todd KM, Yen-Lieberman B, Kaul K, Mangold K, Shulman ST. 2010. Unique finding of a 2009 H1N1 influenza virus-positive clinical sample suggests matrix gene sequence variation. J. Clin. Microbiol. 48:665-666.
3. Novak-Weekly SM, Marlowe EM, Poulter M, Dwyer D, Speers D, Rawlinson W, Baleriola C, Robinson CC. 2012. Evaluation of the Cepheid Xpert Flu assay for rapid identification and differentiation of influenza A, influenza A 2009 H1N1, and influenza B viruses. J. Clin. Microbiol. 50:1704-1710.
4. Tang Y, Lowery KS, Valsamakis A, Schaefer VC, Chappell JD, White-Abell J, Quinn CD, Li H, Washington CA, Cromwell J, Ciamanco CM, Forman M, Holden J, Rothman RE, Parker ML, Ortenberg EV, Zhang L, Lin Y, Gaydos CA. 2013. Clinical accuracy of a PLEX-ID flu device for simultaneous detection and identification of influenza viruses A and B. J. Clin. Microbiol. 51:40-45.
5. Zitterkopf NL, Leekha S, Espy MJ, Wood CM, Sampathkumar P, Smith TF. 2006. Relevance of influenza A virus detection by PCR, shell vial assay, and tube cell culture to rapid reporting procedures. J. Clin. Microbiol. 44:3366-3367. (Pubitemid 44413778)