Images in electroconvulsive therapy: Pilot impressions suggesting that ECT reduces excitatory synapses in the basolateral amygdala

Indian Journal of Psychiatry

Volumn 55, Issue 2, 2013, Pages 204-205

  Khaleel, Nagarchi ^a   Ravindranath, Roopa ^a   Chandrasekhar Sagar, B K ^b   Andrade, Chittaranjan ^c  

^a ST JOHN'S NATIONAL ACADEMY OF HEALTH SCIENCES   (India)

^b Electron Microscopy Laboratory   (India)

^c NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

Author keywords

Amygdala; depression; electroconvulsive therapy; electron microscopy; excitatory synapses; inhibitory synapses; neuroplasticity; posttraumatic stress disorder

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASOLATERAL AMYGDALA; CONTROLLED STUDY; ELECTRIC SHOCK; ELECTROCONVULSIVE THERAPY; MAGNIFICATION RADIOGRAPHY; MALE; NONHUMAN; RAT; SHAM PROCEDURE; SYNAPSE; TRANSMISSION ELECTRON MICROSCOPY;

EID: 84878452637     PISSN: 00195545     EISSN: 19983794     Source Type: Journal    
DOI: 10.4103/0019-5545.111471     Document Type: Article

References (4)

1. Andrade C, Rao NS. How antidepressant drugs act: A primer on neuroplasticity as the eventual mediator of antidepressant efficacy. Indian J Psychiatry 2010;52:378-86.
2. Sackeim HA, Prudic J, Devanand DP, Kiersky JE, Fitzsimons L, Moody BJ, et al. Effects of stimulus intensity and electrode placement on the efficacy and cognitive effects of electroconvulsive therapy. N Engl J Med 1993;328:839-46.
3. Margoob MA, Ali Z, Andrade C. Efficacy of ECT in chronic, severe, antidepressant- and CBT-refractory PTSD: An open, prospective study. Brain Stimul 2010;3:28-35.
4. Khaleel N, Roopa R, Smitha JS, Andrade C. Images in electroconvulsive therapy: ECT attenuates dendritic arborization in the basolateral amygdala. J ECT 2013. In press.