Improved sensitivity by applying spectral unmixing prior to fluorescent tomography

Biomedical Optics, BIOMED 2008

Volumn , Issue , 2008, Pages

  Xu, Heng ^a   Kuo, Chaincy ^a   Rice, Brad ^a  

^a Caliper Life Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENCE; FLUOROPHORES;

MULTIPLE WAVELENGTHS; SPECTRAL UNMIXING;

TOMOGRAPHY;

EID: 84878442014     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1364/biomed.2008.bmc1     Document Type: Conference Paper

References (4)

1. J. R. Mansfield, K. W. Gossage, C. C. Hoyt and R. M. Levenson, "Autofluorescence removal, multiplexing, and automated analysis methods for in-vivo fluorescence imaging," Journal of Biomedical Optics 10, - (2005).
2. T. Zimmermann, "Spectral imaging and linear unmixing in light microscopy," Microscopy Techniques 95, 245-265 (2005).
3. R. Tauler, B. Kowalski and S. Fleming, "Multivariate Curve Resolution Applied to Spectral Data from Multiple Runs of an Industrial- Process," Analytical Chemistry 65, 2040-2047 (1993).
4. C. Kuo, O. Coquoz, T. L. Troy, H. Xu and B. W. Rice, "Three-dimensional reconstruction of in vivo bioluminescent sources based on multispectral imaging," J Biomed Opt 12, 024007 (2007).