Dasatinib targets chronic myeloid leukemia-CD34+ progenitors as effectively as it targets mature cells

Haematologica

Volumn 98, Issue 6, 2013, Pages 896-900

  Hiwase, Devendra K ^a,b,c   Saunders, Verity A ^a,b   Nievergall, Eva ^a,b   Ross, Douglas D ^d   White, Deborah L ^a,b,c   Hughes, Timothy P ^a,b,c  

^a Haematology Division   (Australia)

^b CENTRE FOR CANCER BIOLOGY   (Australia)

^c UNIVERSITY OF ADELAIDE   (Australia)

^d UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; BREAST CANCER RESISTANCE PROTEIN; CD34 ANTIGEN; CD38 ANTIGEN; CRK LIKE PROTEIN; DASATINIB; MULTIDRUG RESISTANCE PROTEIN 1; PHOSPHOTYROSINE;

ARTICLE; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MONONUCLEAR CELL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

ANTIGENS, CD34; ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; CELLS, CULTURED; FUSION PROTEINS, BCR-ABL; HUMANS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; LEUKOCYTES, MONONUCLEAR; NEOPLASM PROTEINS; NEOPLASTIC STEM CELLS; P-GLYCOPROTEIN; PROTEIN KINASE INHIBITORS; PYRIMIDINES; SUBSTRATE SPECIFICITY; THIAZOLES;

EID: 84878441533     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2012.070268     Document Type: Article

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