Development and validation of Vierdot's and q-ratio method for the estimation of Paracetamol, Domperidone and Flunarizine in solid oral dosage form

International Journal of Pharmacy and Pharmaceutical Sciences

Volumn 5, Issue SUPPL. 2, 2013, Pages 347-351

  Sharma, Sandip K ^a   Barot, Gaurang B ^a   Multani, Parmeshwari J ^a  

^a Saraswati Institute of Pharmaceutical Sciences   (India)

Author keywords

Domperidone; Flunarizine; Paracetamol; Q ratio method; Vierdot's method

Indexed keywords

DOMPERIDONE; FLUNARIZINE; PARACETAMOL;

ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; DRUG DETERMINATION; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LINEARITY; MEASUREMENT ACCURACY; MEASUREMENT PRECISION; Q RATIO METHOD; RANGE; ULTRAVIOLET SPECTROPHOTOMETRY; VALIDATION STUDY; VIERDOTS METHOD;

EID: 84878429241     PISSN: None     EISSN: 09751491     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Indian Pharmacopoeia-2007, Govt of India Ministry of Health and Family Wellfare, Indian Pharmacopoeia Commission, Vol-2,3, 434-435, 902-903.
2. Sweetman, SC, Martindale: The complete Drug Reference, 34th edition, Pharmaceutical Press, London, 2005, 50.3.
3. The Merck Index: An encyclopedia of chemicals, drugs and biologicals, Merck Research Laboratories, 14th edition, Domperidone, (3418), 578.
4. Holmes B, Brogden. RN, Heel RC, Speight TM, Avery GS Flunarizine A Review of Its Pharmacodynamic and Pharmacokinetic Properties and Therapeutic Use. Drugs Evaluation 1984; 27(1): 6-44.
5. Bhudavari.S. The Merck Index: An Encyclopedia of chemicals, Drugs and Biologicals, Merck and co., 12th edition, 1996: 702.
6. British pharmacopoeia-2008, The Department of Health and Social Services and Public Safety, British Pharmacopoeia Commission, Vol-II, 2566-2567.
7. Doshi AK, Patel BN, Patel CN Development and validation of spectrophotometric method for simultaneous determination of propranolol hydrochloride and flunarizine dihydrochloride in their combined dosage formulation. Int. J. Pharma. Sci. & Res. 2012; 3(6): 1741-44.
8. Rana S, Pandya J, Solanki S, Patel M Development and Validation of Spectrophotometric method for Simultaneous estimation of Lafutidine and Domperidone in combined dosage form by area under curve method. Int. J. D. Dev. & Res. 2012; 4(1): 257-262.
9. Prabu SL, Shirwaikar A, Kumar DC, Joseph A, Kumar R Simultaneous Estimation of Esomeprazole and Domperidone by UV Spectrophotometric Method. Int. J Pharma. Sci. 2008; 70(1): 128-131.
10. Kalra K, Naik S, Jarmal G, Mishra N Spectrophotometric method for simultaneous estimation of paracetamol and domperidone in tablet formulation. Asian J. Res. Chem. 2009; 2(2): 112-114.
11. Delvadiya K, Kimbahune R, Kabra P, Patel P Spectrophotometric simultaneous analysis of paracetamol, propyphenazone and caffeine in tablet dosage form. Int. J. Pharm. Pharm. Sci. 2011; 3(3): 170-174.
12. Patil AS, Shirkhedkar AA, Surana S, Nawale PS Simultaneous determination of propranolol hydrochloride and flunarizine dihydrochloride in bulk and capsule using reversed-phase high-performance thin layer chromatography / densitometry, J. Chil. Chem. Soc 2012; 57(1): 1033-1035.
13. Ahir KB, Pateliz EM, Mehta FA Simultaneous Estimation of Tramadol HCl, Paracetamol and Domperidone in Pharmaceutical Formulation by Thin-Layer Chromatographic-Densitometricmethod, http://www.pharmatutor.org/articles/estimation-tramadol-paracetamol-domperidone-pharmaceutical-formulation-thin-layer-chromatographic-densitometric-method
14. Vaghela KM, Patel BH, Patel RP Development and validation of HPLC method for the simultaneous estimation of propranolol hydrochloride and flunarizine dihydrochloride in bulk & pharmaceutical dosage form. Inventi Rapid: Pharm Anal. & QA 2012; 69(1): 142-144
15. Karthikeyen V, Vaidhalingam., Yuvraj G, Nema RK Simultaneous estimation of paracetamol, chlorzoxazone and aceclofenac in pharmaceutical formulation by HPLC method. Int. J. ChemTech Res. 2009; 1(3): 457-460.
16. Sharma. S, Sharma A, Singh O, Chaturvedi A, Verma V, Arya R, Singh U RP-HPLC Method Devlopment and Validation of Domperidone in Solid Dosage Form. The Pharma J. 2012; 1(4): 16-20.
17. Shaikh KA, Patil SD Stability indicating rapid RP-HPLC method for the determination of Drotaverine hydrochloride, Domperidone and paracetamol in pharmaceutical dosage forms. Der Pharmacia Lett. 2010; 2(4): 355-364
18. Joshi R, Sharma R Development and validation of RP-HPLC method for simultaneous estimation of three-component tablet formulation containing acetaminophen, chlorzoxazone and aceclofenac. Analytical Lett., 2008; 41(18): 3297-3308.
19. Tsvetkova B, Kostova B, Pencheva I, Zlatkov A, Rachev D, Peikov P Validated LC method for simultaneous analysis of paracetamol and caffeine in model tablet formulation. Int J Pharma Pharma Sci. 2012; 4(4): 680-684.
20. Q2 (R1)-Validation of analytical methods, Text and Methodology, International Conference on Harmonization of Technical Requirements for Registration of Pharmaceutical for Human use, 2005.