Increased serum brain-derived neurotrophic factor (BDNF) levels in patients with narcolepsy

Neuroscience Letters

Volumn 544, Issue , 2013, Pages 31-35

  Klein, Anders B ^a   Jennum, Poul ^b   Knudsen, Stine ^b   Gammeltoft, Steen ^b   Mikkelsen, Jens D ^a  

^a Rigshospitalet   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

BDNF; Hypocretin; Narcolepsy; NGF; Orexin; Sleep

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; NERVE GROWTH FACTOR; OREXIN;

ADULT; AGED; ARTICLE; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE DURATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MALE; NARCOLEPSY; POLYSOMNOGRAPHY; PRIORITY JOURNAL; RADIOIMMUNOASSAY; SLEEP PARAMETERS;

ADULT; AGED; BODY MASS INDEX; FEMALE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; NARCOLEPSY; NERVE GROWTH FACTORS; NEUROPEPTIDES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 84878391189     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2013.03.031     Document Type: Article

References (30)

1. Brandt J.A., Churchill L., Guan Z., Fang J., Chen L., Krueger J.M. Sleep deprivation but not a whisker trim increases nerve growth factor within barrel cortical neurons. Brain Res. 2001, 898:105-112.
2. Brunoni A.R., Lopes M., Fregni F. A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. Int. J. Neuropsychopharmacol. 2008, 11:1169-1180.
3. Bullo M., Peeraully M.R., Trayhurn P., Folch J., Salas-Salvado J. Circulating nerve growth factor levels in relation to obesity and the metabolic syndrome in women. Eur. J. Endocrin. 2007, 157:303-310.
4. Cirelli C., Tononi G. Differential expression of plasticity-related genes in waking and sleep and their regulation by the noradrenergic system. J. Neurosci. 2000, 20:9187-9194.
5. Conti B., Maier R., Barr A.M., Morale M.C., Lu X., Sanna P.P., Bilbe G., Hoyer D., Bartfai T. Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy sleep deprivation and fluoxetine. Mol. Psychiatr. 2007, 12:167-189.
6. Dauvilliers Y., Arnulf I., Mignot E. Narcolepsy with cataplexy. Lancet 2007, 369:499-511.
7. Faraguna U., Vyazovskiy V.V., Nelson A.B., Tononi G., Cirelli C. A causal role for brain-derived neurotrophic factor in the homeostatic regulation of sleep. J. Neurosci. 2008, 28:4088-4095.
8. Gorgulu Y., Caliyurt O. Rapid antidepressant effects of sleep deprivation therapy correlates with serum BDNF changes in major depression. Brain Res. Bull. 2009, 80:158-162.
9. Grimsholm O., Rantapaa-Dahlqvist S., Dalen T., Forsgren S. BDNF in RA: downregulated in plasma following anti-TNF treatment but no correlation with inflammatory parameters. Clin. Rheum. 2008, 27:1289-1297.
10. Hallmayer J., Faraco J., Lin L., Hesselson S., Winkelmann J., Kawashima M., Mayer G., Plazzi G., Nevsimalova S., Bourgin P., Hong S.C., Honda Y., Honda M., Hogl B., Longstreth W.T., Montplaisir J., Kemlink D., Einen M., Chen J., Musone S.L., Akana M., Miyagawa T., Duan J., Desautels A., Erhardt C., Hesla P.E., Poli F., Frauscher B., Jeong J.H., Lee S.P., Ton T.G., Kvale M., Kolesar L., Dobrovolna M., Nepom G.T., Salomon D., Wichmann H.E., Rouleau G.A., Gieger C., Levinson D.F., Gejman P.V., Meitinger T., Young T., Peppard P., Tokunaga K., Kwok P.Y., Risch N., Mignot E. Narcolepsy is strongly associated with the T-cell receptor alpha locus. Nat. Gen. 2009, 41:708-711.
11. Himeda T., Tounai H., Hayakawa N., Araki T. Postischemic alterations of BDNF, NGF HSP 70 and ubiquitin immunoreactivity in the gerbil hippocampus: pharmacological approach. Cell. Mol. Neurobiol. 2007, 27:229-250.
12. Ji Y., Lu Y., Yang F., Shen W., Tang T.T., Feng L., Duan S., Lu B. Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons. Nat. Neurosci. 2010, 13:302-309.
13. Jung S.H., Kim J., Davis J.M., Blair S.N., Cho H.C. Association among basal serum BDNF cardiorespiratory fitness and cardiovascular disease risk factors in untrained healthy Korean men. Eur. J. Appl. Physiol. 2011, 111:303-311.
14. Kerschensteiner M., Gallmeier E., Behrens L., Leal V.V., Misgeld T., Klinkert W.E., Kolbeck R., Hoppe E., Oropeza-Wekerle R.L., Bartke I., Stadelmann C., Lassmann H., Wekerle H., Hohlfeld R. Activated human T cells B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation?. J. Exp. Med. 1999, 189:865-870.
15. Klein A.B., Williamson R., Santini M.A., Clemmensen C., Ettrup A., Rios M., Knudsen G.M., Aznar S. Blood BDNF concentrations reflect brain-tissue BDNF levels across species. Int. J. Neuropsychopharmcol. 2011, 14:347-353.
16. Knudsen S., Gammeltoft S., Jennum P.J. Rapid eye movement sleep behaviour disorder in patients with narcolepsy is associated with hypocretin-1 deficiency. Brain 2010, 133:568-579.
17. Knudsen S., Jennum P.J., Alving J., Sheikh S.P., Gammeltoft S. Validation of the ICSD-2 criteria for CSF hypocretin-1 measurements in the diagnosis of narcolepsy in the Danish population. Sleep 2010, 33:169-176.
18. Kornum B.R., Faraco J., Mignot E. Narcolepsy with hypocretin/orexin deficiency infections and autoimmunity of the brain. Curr. Opin. Neurobiol. 2011, 21:897-903.
19. Lang U.E., Gallinat J., Danker-Hopfe H., Bajbouj M., Hellweg R. Nerve growth factor serum concentrations in healthy human volunteers: physiological variance and stability. Neurosci. Lett. 2003, 344:13-16.
20. Martinowich K., Schloesser R.J., Jimenez D.V., Weinberger D.R., Lu B. Activity-dependent brain-derived neurotrophic factor expression regulates cortistatin-interneurons and sleep behavior. Mol. Brain 2011, 4:11.
21. Mignot E. Genetic and familial aspects of narcolepsy. Neurology 1998, 50:S16-S22.
22. Monteleone P., Tortorella A., Martiadis V., Serritella C., Fuschino A., Maj M. Opposite changes in the serum brain-derived neurotrophic factor in anorexia nervosa and obesity. Psychosom. Med. 2004, 66:744-748.
23. Peyron C., Faraco J., Rogers W., Ripley B., Overeem S., Charnay Y., Nevsimalova S., Aldrich M., Reynolds D., Albin R., Li R., Hungs M., Pedrazzoli M., Padigaru M., Kucherlapati M., Fan J., Maki R., Lammers G.J., Bouras C., Kucherlapati R., Nishino S., Mignot E. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat. Med. 2000, 6:991-997.
24. Rasmussen P., Brassard P., Adser H., Pedersen M.V., Leick L., Hart E., Secher N.H., Pedersen B.K., Pilegaard H. Evidence for a release of brain-derived neurotrophic factor from the brain during exercise. Exp. Physiol. 2009, 94:1062-1069.
25. Saper C.B., Fuller P.M., Pedersen N.P., Lu J., Scammell T.E. Sleep state switching. Neuron 2010, 68:1023-1042.
26. Sato Y., Chin Y., Kato T., Tanaka Y., Tozuka Y., Mase M., Ageyama N., Ono F., Terao K., Yoshikawa Y., Hisatsune T. White matter activated glial cells produce BDNF in a stroke model of monkeys. Neurosci. Res. 2009, 65:71-78.
27. Schuld A., Hebebrand J., Geller F., Pollmacher T. Increased body-mass index in patients with narcolepsy. Lancet 2000, 355:1274-1275.
28. Sturzenegger C., Bassetti C.L. The clinical spectrum of narcolepsy with cataplexy: a reappraisal. J. Sleep Res. 2004, 13:395-406.
29. Yan Q., Rosenfeld R.D., Matheson C.R., Hawkins N., Lopez O.T., Bennett L., Welcher A.A. Expression of brain-derived neurotrophic factor protein in the adult rat central nervous system. Neuroscience 1997, 78:431-448.
30. Zuccato C., Cattaneo E. Brain-derived neurotrophic factor in neurodegenerative diseases. Nat. Rev. 2009, 5:311-322.