Clinical application of olfactory ensheathing cells in the treatment of spinal cord injury

Journal of International Medical Research

Volumn 41, Issue 2, 2013, Pages 473-481

  Rao, Yaojian ^a   Zhu, Wenxiao ^a   Liu, Huijuan ^a   Jia, Chunxia ^a   Zhao, Qingan ^a   Wang, Yongjun ^b  

^a Luoyang Orthopaedic Traumatological Hospital   (China)

^b SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Asia impairment scale; Functional independence measure; Multiple transplantation; Olfactory ensheathing cells; Spinal cord injury

Indexed keywords

ADULT; ADVERSE OUTCOME; AMERICAN SPINAL INJURY ASSOCIATION IMPAIRMENT SCALE; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; BLADDER FUNCTION; CERVICAL SPINAL CORD INJURY; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CLINICAL EVALUATION; CONTROLLED STUDY; DISEASE DURATION; FEMALE; FOLLOW UP; FUNCTIONAL INDEPENDENCE MEASURE; HUMAN; MALE; MOTOR ACTIVITY; NUCLEAR MAGNETIC RESONANCE IMAGING; OLFACTORY ENSHEATHING CELL; PATIENT SAFETY; THERAPY EFFECT;

EID: 84878369410     PISSN: 03000605     EISSN: 14732300     Source Type: Journal    
DOI: 10.1177/0300060513476426     Document Type: Article

References (25)

1. Van den Berg ME, Castellote JM, Mahillo- Fernandez I, et al. Incidence of spinal cord injury worldwide: a systematic review. Neuroepidemiology 2010; 34: 184-192.
2. Wyndaele M and Wyndaele JJ. Incidence, prevalence and epidemiology of spinal cord injury: what learns a worldwide literature survey? Spinal Cord 2006; 44: 523-529.
3. Fehlings MG and Tator CH. An evidencebased review of decompressive surgery in acute spinal cord injury: rationale, indications, and timing based on experimental and clinical studies. J Neurosurg 1999; 91(suppl): 1-11.
4. Fehlings MG and Perrin RG. The timing of surgical intervention in the treatment of spinal cord injury: a systematic review of recent clinical evidence. Spine (Phila Pa 1976) 2006; 31(suppl): S28-S36.
5. Sköld C, Levi R and Seiger A. Spasticity after traumatic spinal cord injury: nature, severity, and location. Arch Phys Med Rehabil 1999; 80: 1548-1557.
6. Dijkers M. Quality of life after spinal cord injury: a meta analysis of the effects of disablement components. Spinal Cord 1997; 35: 829-840.
7. Kim BG, Hwang DH, Lee SI, et al. Stem cellbased cell therapy for spinal cord injury. Cell Transplant 2007; 16: 355-364.
8. Hernández J, Torres-Espín A and Navarro X. Adult stem cell transplants for spinal cord injury repair: current state in preclinical research. Curr Stem Cell Res Ther 2011; 6: 273-287.
9. Das AK, Gopurappilly R and Parhar I. Current status and prospective application of stem cell-based therapies for spinal cord injury. Curr Stem Cell Res Ther 2011; 6: 93-104.
10. Kan EM, Ling EA and Lu J. Stem cell therapy for spinal cord injury. Curr Med Chem 2010; 17: 4492-4510.
11. Wu S, Suzuki Y, Ejiri Y, et al. Bone marrow stromal cells enhance differentiation of cocultured neurosphere cells and promote regeneration of injured spinal cord. J Neurosci Res 2003; 72: 343-351.
12. Chopp M, Zhang XH, Li Y, et al. Spinal cord injury in rat: treatment with bone marrow stromal cell transplantation. Neuroreport 2000; 11: 3001-3005.
13. Nandoe Tewarie RD, Hurtado A, Levi AD, et al. Bone marrow stromal cells for repair of the spinal cord: towards clinical application. Cell Transplant 2006; 15: 563-577.
14. Jani HR and Raisman G. Ensheathing cell cultures from the olfactory bulb and mucosa. Glia 2004; 47: 130-137.
15. Su Z and He C. Olfactory ensheathing cells: biology in neural development and regeneration. Prog Neurobiol 2010; 92: 517-532.
16. Radtke C and Wewetzer K. Translating basic research into clinical practice or what else do we have to learn about olfactory ensheathing cells? Neurosci Lett 2009; 456: 133-136.
17. Radtke C, Aizer AA, Agulian SK, et al. Transplantation of olfactory ensheathing cells enhances peripheral nerve regeneration after microsurgical nerve repair. Brain Res 2009; 1254: 10-17.
18. Cohen ME, Ditunno JF Jr, Donovan WH, et al. A test of the 1992 International Standards for Neurological and Functional Classification of Spinal Cord Injury. Spinal Cord 1998; 36: 554-560.
19. Girard SD, Devéze A, Nivet E, et al. Isolating nasal olfactory stem cells from rodents or humans. J Vis Exp 2011; 54: e2762.
20. Hamilton BB, Laughlin JA, Fiedler RC, et al. Interrater reliability of the 7-level Functional Independence Measure (FIM). Scand J Rehabil Med 1994; 26: 115-119.
21. Baptiste DC and Fehlings MG. Update on the treatment of spinal cord injury. Prog Brain Res 2007; 161: 217-233.
22. Fairless R and Barnett SC. Olfactory ensheathing cells: their role in central nervous system repair. Int J Biochem Cell Biol 2005; 37: 693-699.
23. Kocsis JD, Lankford KL, Sasaki M, et al. Unique in vivo properties of olfactory ensheathing cells that may contribute to neural repair and protection following spinal cord injury. Neurosci Lett 2009; 456: 137-142.
24. Barnett SC and Riddell JS. Olfactory ensheathing cells (OECs) and the treatment of CNS injury: advantages and possible caveats. J Anat 2004; 204: 57-67.
25. Swijnenburg RJ, Schrepfer S, Govaert JA, et al. Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts. Proc Natl Acad Sci USA 2008; 105: 12991-12996.