Pharmacokinetics and pharmacodynamics of orally administered clonidine: A model-based approach

Hormone Research in Paediatrics

Volumn 79, Issue 5, 2013, Pages 300-309

  Klein, R H ^a   Alvarez Jimenez, R ^a   Sukhai, R N ^a   Oostdijk, W ^a   Bakker, B ^b   Reeser, H M ^c   Ballieux, B E P B ^a   Hu, P ^d   Klaassen, E S ^a   Freijer, J ^a   Burggraaf, J ^a   Cohen, A F ^a   Wit, J M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b REINIER DE GRAAF HOSPITAL   (Netherlands)

^c JULIANA CHILDREN S HOSPITAL   (Netherlands)

^d PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

Author keywords

Child; Clonidine; Diagnosis; Growth hormone deficiency; Growth hormone provocative testing; Pharmacokinetics

Indexed keywords

CLONIDINE; GLUCOSE; GROWTH HORMONE; HYDROCORTISONE;

ADOLESCENT; ARTICLE; BLOOD ANALYSIS; BRADYCARDIA; CHILD; CLINICAL ARTICLE; DIASTOLIC BLOOD PRESSURE; DRUG BLOOD LEVEL; FEMALE; GROWTH HORMONE DEFICIENCY; HUMAN; HYPOTENSION; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SEDATION; SYSTOLIC BLOOD PRESSURE; VITAL STATISTICS; BLOOD SAMPLING; CONTROLLED STUDY; DIAGNOSTIC TEST; DOSE RESPONSE; HEART RATE; HORMONE RESPONSE; MODEL; SIDE EFFECT;

ADMINISTRATION, ORAL; ADOLESCENT; CHILD; CHILD, PRESCHOOL; CLONIDINE; FEMALE; HUMAN GROWTH HORMONE; HUMANS; MALE; MODELS, BIOLOGICAL; SYMPATHOLYTICS; TIME FACTORS;

EID: 84878353661     PISSN: 16632818     EISSN: 16632826     Source Type: Journal    
DOI: 10.1159/000350819     Document Type: Article

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