Conjugation, characterization and toxicity of lipophosphoglycan-polyacrylic acid conjugate for vaccination against leishmaniasis

Journal of Biomedical Science

Volumn 20, Issue 1, 2013, Pages

  Topuzogullari, Murat ^a   Cakir Koc, Rabia ^b   Dincer Isoglu, Sevil ^a   Bagirova, Melahat ^a   Akdeste, Zeynep ^a   Elcicek, Serhat ^c   Oztel, Olga N ^a   Yesilkir Baydar, Serap ^a   Canim Ates, Sezen ^a   Allahverdiyev, Adil M ^a  

^a YILDIZ TECHNICAL UNIVERSITY   (Turkey)

^b ISTANBUL YENI YUZYIL UNIVERSITY   (Turkey)

^c FIRAT UNIVERSITY   (Turkey)

Author keywords

Adjuvant; Conjugation; Delivery; Leishmania; Polymer; Vaccine

Indexed keywords

LEISHMANIA VACCINE; LIPOPHOSPHOGLYCAN; POLYACRYLIC ACID; ACRYLIC ACID RESIN; CARBOPOL 940; GLYCOSPHINGOLIPID; VACCINE;

ANIMAL CELL; ARTICLE; CYTOTOXICITY; DRUG DELIVERY SYSTEM; IMMUNOLOGY; LEISHMANIASIS; MACROPHAGE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PARASITE; PRIORITY JOURNAL; VACCINATION; ANIMAL; CELL LINE; CHEMISTRY; MOUSE;

MURINAE;

ACRYLIC RESINS; ANIMALS; CELL LINE; GLYCOSPHINGOLIPIDS; LEISHMANIASIS; LEISHMANIASIS VACCINES; MICE; VACCINATION; VACCINES, CONJUGATE;

EID: 84878348058     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-20-35     Document Type: Article

References (20)

1. From synthetic polyelectrolytes to polymer-subunit vaccines. Kabanov VA, Pure Appl Chem 2004 76 1659 1678 10.1351/pac200476091659
2. Polyphosphazene polyelectrolytes: a link between the formation of noncovalent complexes with antigenic proteins and immunostimulating activity. Andrianov AK, Marin A, Roberts BE, Biomacromolecules 2005 6 1375 1379 10.1021/bm049329t 15877355
3. Immunogenic Cu2 + -induced biopolymer systems comprising a steroid hormone, protein antigen, and synthetic polyelectrolytes. Basalp A, Mustafaeva Z, Mustafaev M, Hybridoma 2002 21 45 51
4. pH-sensitive drug delivery system using OW emulsion. Yuk SH, Cho SH, Lee HB, J Control Release 1995 37 69 74 10.1016/0168-3659(95)00065-G
5. Immobilization of penicillin G acylase on aminoalkylated polyacrylic supports. Bianchi D, Golini P, Bortolo R, Cesti P, Enzyme Microb Technol 1996 18 592 596 10.1016/0141-0229(95)00149-2
6. Stimulation of DNA synthesis in mouse lymphoid cells by polyanions in vitro. I. Target cells and possible mode of action. Diamantstein T, Vogt W, Ruhl H, Bochert G, Eur J Immunol 1973 3 488 493 10.1002/eji.1830030807 4585312
7. Critical nature of the effect of the degree of polyelectrolyte polymerization on immunostimulating properties. Kabanov VA, Mustafaev MI, Nekrasov AV, Norimov A, Petrov RV, Dokl Akad Nauk SSSR 1984 274 998 1001 6610543
8. Effect of heparin on the immunogenicity of electrostatic covalent albumin complexes with synthetic polyions. Immunogenicity of the triple covalent complex polyelectrolyte-protein-heparin. Petrov RV, Kabanov VA, Khaitov RM, Mustafaev MI, Norimov A, Mol Gen Mikrobiol Virusol 1986 30 35
9. Leishmaniasis: current situation and new perspectives. Desjeux P, Comp Immunol Microbiol Infect Dis 2004 27 305 318 10.1016/j.cimid.2004.03.004 15225981
10. Protection against cutaneous leishmaniasis by intranasal vaccination with lipophosphoglycan. Pinheiro RO, Pinto EF, de Matos Guedes HL, de Mattos KA, Saraiva EM, de Mendonça SCF, Rossi-Bergmann B, Vaccine 2007 25 2716 2722 10.1016/j.vaccine.2006.05.093 16814903
11. New advances in microsphere-based single-dose vaccines. Hanes J, Cleland JL, Langer R, Adv Drug Deliv Rev 1997 28 97 119 10.1016/S0169-409X(97)00053-7 10837567
12. Leishmania tropica: the effect of darkness and light on biological activities in vitro. Allahverdiyev AM, Koc RC, Ates SC, Bagirova M, Elcicek S, Oztel ON, Exp Parasitol 2011 128 318 323 10.1016/j.exppara.2011.04.002 21510933
13. Intra-species and stage-specific polymorphisms in lipophosphoglycan structure control Leishmania donovani-sand fly interactions. Mahoney AB, Sacks DL, Saraiva E, Modi G, Turco SJ, Biochemistry 1999 38 9813 9823 10.1021/bi990741g 10433687
14. Quantitation of Leishmania lipophosphoglycan repeat units by capillary electrophoresis. Barron TL, Turco SJ, Biochim Biophys Acta, Gen Subj 2006 1760 710 714 10.1016/j.bbagen.2005.10.007
15. Matrix-assisted laser desorption ionization/mass spectrometry of polymers (MALDI-MS). Montaudo G, Montaudo MS, Samperi F, Mass spectrometry of polymers Boca Raton: CRS Press LLC, Montaudo G, Lattimer RP, 2002 431 446
16. Safety and efficacy of an inactivated Carbopol-adjuvanted goose haemorrhagic polyomavirus vaccine for domestic geese. Gelfi J, Pappalardo M, Claverys C, Peralta B, Guérin JL, Avian Pathol 2010 39 111 116 10.1080/03079451003604647 20390545
17. Alkyl-esters of polyacrylic acid as vaccine adjuvants. Hilgers L, Nicolas I, Lejeune G, Dewil E, Strebelle M, Boon B, Vaccine 1998 16 1575 1581 10.1016/S0264-410X(98)00047-4 9711806
18. Potent adaptive immune responses induced against HIV-1 gp140 and influenza virus HA by a polyanionic carbomer. Krashias G, Simon AK, Wegmann F, Kok WL, Ho LP, Stevens D, Skehel J, Heeney JL, Moghaddam AE, Sattentau QJ, Vaccine 2010 28 2482 2489 10.1016/j.vaccine.2010.01.046 20132920
19. PCPP as a parenteral adjuvant for diverse antigens. Payne L, Van Nest G, Barchfeld G, Siber G, Gupta R, Jenkins S, Dev Biol Stand 1998 92 79 9554261
20. Study of the mechanisms of the action of heparin and poly-4-vinylpyridine on immunogenesis. Petrov R, Gvozdetski A, Gorokhov A, Evdakov V, Kabanov V, Zh Mikrobiol Epidemiol Immunobiol 1974 37