Questions about the accuracy of polar body analysis for preimplantation genetic screening

Human Reproduction

Volumn 28, Issue 6, 2013, Pages 1732-1733

  Christopikou, Dimitra ^a   Handyside, Alan H ^a  

^a Embryogenesis Inc   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYSIS; ANEUPLOIDY; BLASTOCYST; CHROMOSOME MOSAICISM; DIAGNOSTIC ACCURACY; GENETIC SCREENING; HUMAN; LETTER; MATERNAL AGE; POLAR BODY; POLAR BODY ANALYSIS; PRENATAL DIAGNOSIS; SINGLE NUCLEOTIDE POLYMORPHISM; BLASTOMA; CHROMOSOME SEGREGATION; CYTOLOGY; EMBRYO DEVELOPMENT; FEMALE; GENETICS; MEIOSIS; PHYSIOLOGY; PROCEDURES; TROPHOBLAST;

BLASTOMERES; CHROMOSOME SEGREGATION; EMBRYONIC DEVELOPMENT; FEMALE; HUMANS; MEIOSIS; POLAR BODIES; PREIMPLANTATION DIAGNOSIS; TROPHOBLASTS;

EID: 84878330838     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/det076     Document Type: Letter

References (4)

1. Capalbo A, Bono S, Spizzichino L, Biricik A, Baldi M, Colamaria S, Ubaldi FM, Rienzi L, Fiorentino F. Sequential comprehensive chromosome analysis on polar bodies, blastomeres and trophoblast: insights into female meiotic errors and chromosomal segregation in the preimplantation window of embryo development. Hum Reprod 2013;28;509-518.
2. Christopikou D, Tsorva E, Economou K, Shelley P, Davies S, Mastrominas M, Handyside AH. Polar body analysis by array comparative genomic hybridisation accurately predicts aneuploidies of maternal meiotic origin in cleavage stage embryos of women of advanced maternal age. Hum Reprod 2013;28:1426-1434.
3. Handyside AH, Harton GL, Mariani B, Thornhill AR, Affara N, Shaw MA, Griffin DK. Karyomapping: a universal method for genome wide analysis of genetic disease based on mapping crossovers between parental haplotypes. J Med Genet 2010;47:651-658.
4. Yang Z, Liu J, Collins GS, Salem SA, Liu X, Lyle SS, Peck AC, Sills ES, Salem RD. Selection of single blastocysts for fresh transfer via standard morphology assessment alone and with array CGH for good prognosis IVF patients: results from a randomized pilot study. Mol Cytogenet 2012;5:24.