Autologous blood products in musculoskeletal medicine although they are trendy money spinners, best evidence shows little effectiveness

BMJ (Online)

Volumn 346, Issue 7908, 2013, Pages

  Maffulli, Nicola ^a  

^a UNIVERSITY OF SALERNO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EDITORIAL; HUMAN; MENTAL HEALTH; MUSCULOSKELETAL DISEASE; OSTEOPOROSIS; PHYSICAL ACTIVITY; PRIORITY JOURNAL; REGENERATIVE MEDICINE; SOFT TISSUE INJURY; SPORT INJURY; SYSTEMATIC REVIEW; TENDINITIS; THROMBOCYTE RICH PLASMA;

ACHILLES TENDON; BLOOD TRANSFUSION, AUTOLOGOUS; FEMALE; HUMANS; MALE; PAIN MANAGEMENT; RESISTANCE TRAINING; TENDINOPATHY;

EID: 84878314648     PISSN: None     EISSN: 17561833     Source Type: Journal    
DOI: 10.1136/bmj.f2979     Document Type: Editorial

References (14)

1. Bell KJ, Fulcher ML, Rowland DS, Kerse N. Impact of autologous blood injections in treatment of mid-portion Achilles tendinopathy: double blind randomised controlled trial. BMJ 2013;346:f2310.
2. Maffulli N, Longo UG, Loppini M, Spiezia F, Denaro V. New options in the management of tendinopathy. Open Access J Sports Med 2010;1:29-37.
3. Maffulli N, Longo UG, Denaro V. Novel approaches for the management of tendinopathy. J Bone Joint Surg Am 2010;92:2604-13.
4. Orchard JW, Best TM, Mueller-Wohlfahrt HW, Hunter G, Hamilton BH, Webborn N, et al. The early management of muscle strains in the elite athlete: best practice in a world with a limited evidence basis. Br J Sports Med 2008;42:158-9. (Pubitemid 351449129)
5. Marx RE. Platelet-rich plasma (PRP): what is PRP and what is not PRP? Implant Dent 2001;10:225-8.
6. GlobalData. Platelet rich plasma: a market snapshot. 2010. www.docstoc.com/docs/47503668/Platelet-Rich-Plasma-A-Market-Snapshot.
7. Anitua E, Sanchez M, Nurden AT, Nurden P, Orive G, Andia I. New insights into and novel applications for platelet-rich fibrin therapies. Trends Biotechnol 2006;24:227-34.
8. Fufa D, Shealy B, Jacobson M, Kevy S, Murray MM. Activation of platelet-rich plasma using soluble type I collagen. J Oral Maxillofac Surg 2008;66:684-90. (Pubitemid 351381788)
9. De Vos RJ, van Veldhoven PL, Moen MH, Weir A, Tol JL, Maffulli N. Autologous growth factor injections in chronic tendinopathy: a systematic review. Br Med Bull 2010;95:63-77.
10. Sharma P, Maffulli N. Basic biology of tendon injury and healing. Surgeon 2005;3:309-16. (Pubitemid 41488685)
11. De Vos RJ, Weir A, van Schie HT, Bierma-Zeinstra SM, Verhaar JA, Weinans H, et al. Platelet-rich plasma injection for chronic Achilles tendinopathy: a randomized controlled trial. JAMA 2010;303:144-9.
12. Creaney L, Wallace A, Curtis M, Connell D. Growth factor-based therapies provide additional benefit beyond physical therapy in resistant elbow tendinopathy: a prospective, single-blind, randomised trial of autologous blood injections versus platelet-rich plasma injections. Br J Sports Med 2011;45:966-71.
13. Peerbooms JC, Sluimer J, Bruijn DJ, Gosens T. Positive effect of an autologous platelet concentrate in lateral epicondylitis in a double-blind randomized controlled trial: platelet-rich plasma versus corticosteroid injection with a 1-year follow-up. Am J Sports Med 2010;38:255-62.
14. Castricini R, Longo UG, De Benedetto M, Panfoli N, Pirani P, Zini R, et al. Platelet-rich plasma augmentation for arthroscopic rotator cuff repair: a randomized controlled trial. Am J Sports Med 2011;39:258-65.