β1-Adrenoceptor stimulation suppresses endothelial IK Ca-channel hyperpolarization and associated dilatation in resistance arteries

British Journal of Pharmacology

Volumn 169, Issue 4, 2013, Pages 875-886

  Yarova, P L ^a,c   Smirnov, S V ^b   Dora, K A ^a   Garland, C J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b University of Bath   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

adrenoceptor; acetylcholine; adrenergic (ant)agonists; endothelial receptors; PKA

Indexed keywords

1 [(2 CHLOROPHENYL)DIPHENYLMETHYL] 1H PYRAZOLE; 3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; ACETYLCHOLINE; ADENYLATE CYCLASE; ATENOLOL; BETA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM ION; CATECHOLAMINE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; GLIBENCLAMIDE; KT 5720; PROPRANOLOL;

ANIMAL TISSUE; ARTERY DILATATION; ARTERY RESISTANCE; ARTICLE; CALCIUM SIGNALING; CATECHOLAMINE BLOOD LEVEL; CELL MEMBRANE POTENTIAL; CONTROLLED STUDY; ENDOTHELIUM CELL; HYPERPOLARIZATION; MALE; MESENTERIC ARTERY; MYOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER MEMBRANE POTENTIAL;

ACETYLCHOLINE; ADRENERGIC BETA-1 RECEPTOR AGONISTS; ADRENERGIC BETA-1 RECEPTOR ANTAGONISTS; ANIMALS; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENDOTHELIUM, VASCULAR; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MALE; MEMBRANE POTENTIALS; MESENTERIC ARTERIES; MUSCLE, SMOOTH, VASCULAR; MYOGRAPHY; PROTEIN KINASE INHIBITORS; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, BETA-1; SECOND MESSENGER SYSTEMS; VASCULAR RESISTANCE; VASODILATION;

EID: 84878314063     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12160     Document Type: Article

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