Autoimmune polyglandular syndrome type 1 with reversible dilated cardiomyopathy: Complete recovery after correction of hypocalcemia and hypocortisolemia

Journal of Pediatric Endocrinology and Metabolism

Volumn 26, Issue 3-4, 2013, Pages 373-376

  Wani, Arshad Iqbal ^a   Farooqui, Khalid Jamal ^a   Bashir, Mir Iftikhar ^a   Mir, Shahnaz Ahmad ^a   Lone, Ajaz Ahmad ^a   Masoodi, Shariq Rashid ^a  

^a SHER I KASHMIR INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Adrenal insufficiency; Autoimmune poly glandular syndrome type 1; Hypocalcemia; Reversible cardiomyopathy

Indexed keywords

ANTIBIOTIC AGENT; CALCITRIOL; CALCIUM; DIGITALIS; DIGOXIN; DIURETIC AGENT; ENALAPRIL; GLUCONATE CALCIUM; HYDROCORTISONE; PHOSPHORUS; PROPRANOLOL;

ABDOMINAL PAIN; ABNORMALLY LOW SUBSTRATE CONCENTRATION IN BLOOD; ADRENAL INSUFFICIENCY; ALOPECIA AREATA; ARTICLE; AUTOIMMUNE POLYENDOCRINOPATHY CANDIDIASIS ECTODERMAL DYSTROPHY; BASAL GANGLION; BLOOD PRESSURE; BRAIN CALCIFICATION; BRONCHOPNEUMONIA; CALCIUM BLOOD LEVEL; CARDIOMEGALY; CASE REPORT; CHILD; CLINICAL EXAMINATION; COMPUTER ASSISTED TOMOGRAPHY; CONGESTIVE CARDIOMYOPATHY; CONGESTIVE HEART FAILURE; CORTICOTROPIN TEST; DENTAL CARIES; DYSPNEA; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAM; ESOPHAGUS CANDIDIASIS; FEMALE; HEART EJECTION FRACTION; HOSPITALIZED CHILD; HUMAN; HYPERPHOSPHATEMIA; HYPOCALCEMIA; HYPOCORTISOLEMIA; HYPOKINESIA; HYPONATREMIA; MEDICAL HISTORY; MITRAL VALVE REGURGITATION; NAIL DYSTROPHY; PATIENT REFERRAL; PHOSPHATE BLOOD LEVEL; PULSE RATE; QT PROLONGATION; REST; SCHOOL CHILD; SINUS TACHYCARDIA; SKIN PIGMENTATION; SYSTOLIC HEART MURMUR; TETANIC SPASM; THORAX RADIOGRAPHY; VOMITING;

CALCIUM; CARDIOMYOPATHY, DILATED; CHILD; FEMALE; HUMANS; HYDROCORTISONE; HYPOCALCEMIA; MAGNETIC RESONANCE IMAGING; POLYENDOCRINOPATHIES, AUTOIMMUNE; REMISSION INDUCTION; TREATMENT OUTCOME;

EID: 84878301603     PISSN: 0334018X     EISSN: 21910251     Source Type: Journal    
DOI: 10.1515/jpem-2012-0201     Document Type: Article

References (12)

1. Stulz PM, Scheidegger D, Drop LJ, Lowenstein E, Laver MB. Ventricular pump performance during hypocalcemia: clinical and experimental studies. J Thorac Cardiovasc Surg 1979;78:185 - 94. (Pubitemid 10218532)
2. Allolio B, Ehses W, Steffen HM, Muller R. Reduced lymphocyte b2-adrenoceptor density and impaired diastolic left ventricular function in patients with glucocorticoid deficiency. Clin Endocrinol 1994;40:769- 75.
3. Dimitrios AA, Stefan SI, Fotis KP, Athanasios NR, Spyridon TK, et al. Dilated cardiomyopathy and hypoparathyroidism: complete recovery after hypocalcemia correction. Hellenic J Cardiol 2003;44:150 - 4.
4. Conwell LS, Gray LM, Delbridge RG, Thomsett MJ, Batch JA. Reversible cardiomyopathy in paediatric Addison's disease - a cautionary tale. J Pediatr Endocrinol Metab 2003;16:1191 - 5. (Pubitemid 37336866)
5. Owen CJ, Cheetham TD. Diagnosis and management of polyendocrinopathy syndromes. Endocrinol Metab Clin N Am 2009;38:419 - 36.
6. Wolff AS, Erichsen MM, Meager A, Magitta NF, Myhre AG, et al. Autoimmune polyendocrinopathy syndrome type 1 in Norway: phenotypic variation, autoantibodies, and novel mutations in the autoimmune regulator gene. J Clin Endocrinol Metab 2007;92:595 - 603.
7. Laway BA, Ganie MA, War FA, Mir SA, Roshan R, et al. Varying presentation of type 1 polyglandular failure in India. J Pediatr Endocrinol Metab 2010;23:271- 6.
8. Levine SN, Rheams CN. Hypocalcemic heart failure. Am J Med 1985;78:1033 - 5. (Pubitemid 15021270)
9. Bogin E, Massry SG, Harary I. Effect of parathyroid hormone on rat heart cells. J Clin Invest 1981;67: 1215 - 27. (Pubitemid 11090564)
10. Rao MK, Xu A, Narayanan N. Glucocorticoid modulation of protein phosphorylation and sarcoplasmic reticulum function in rat myocardium. Am J Physiol Heart Circ Physiol 2001; 281:H325 - 33.
11. Al-Herbish AS, Bailey JD, Kooh SW. Growth hormone deficiency in autoimmune polyglandular disease type 1. Saudi Med J 2000;21:765-8.
12. Pun T, Chandurkar V. Growth hormone deficiency, short stature, and juvenile rheumatoid arthritis in a patient with autoimmune polyglandular syndrome type 1: case report and brief review of the literature. ISRN Endocrinol 2011;2011:462759.