메뉴 건너뛰기




Volumn 32, Issue 21, 2013, Pages 2622-2630

Arg/Abl2 promotes invasion and attenuates proliferation of breast cancer in vivo

Author keywords

Arg kinase; Breast cancer; invasion; metastasis; proliferation

Indexed keywords

ABL2 KINASE; ARG KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG;

EID: 84878256918     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.284     Document Type: Article
Times cited : (102)

References (38)
  • 1
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144: 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 4
    • 63049090100 scopus 로고    scopus 로고
    • Metastasis: From dissemination to organ-specific colonization
    • Nguyen DX, Bos PD, Massague J. Metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer 2009; 9: 274-284.
    • (2009) Nat Rev Cancer , vol.9 , pp. 274-284
    • Nguyen, D.X.1    Bos, P.D.2    Massague, J.3
  • 5
    • 70350379633 scopus 로고    scopus 로고
    • Regulation of cell migration and morphogenesis by Abl-family kinases: Emerging mechanisms and physiological contexts
    • Bradley WD, Koleske AJ. Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts. J Cell Sci 2009; 122(Part 19): 3441-3454.
    • (2009) J Cell Sci , vol.122 , Issue.PART 19 , pp. 3441-3454
    • Bradley, W.D.1    Koleske, A.J.2
  • 6
    • 0036391801 scopus 로고    scopus 로고
    • The Abl family kinases: Mechanisms of regulation and signaling
    • Pendergast AM. The Abl family kinases: mechanisms of regulation and signaling. Adv Cancer Res 2002; 85: 51-100.
    • (2002) Adv Cancer Res , vol.85 , pp. 51-100
    • Pendergast, A.M.1
  • 7
    • 22244475384 scopus 로고    scopus 로고
    • Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase
    • Derkinderen P, Scales TM, Hanger DP, Leung KY, Byers HL, Ward MA et al. Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase. J Neurosci 2005; 25: 6584-6593.
    • (2005) J Neurosci , vol.25 , pp. 6584-6593
    • Derkinderen, P.1    Scales, T.M.2    Hanger, D.P.3    Leung, K.Y.4    Byers, H.L.5    Ward, M.A.6
  • 8
    • 38949197397 scopus 로고    scopus 로고
    • Emerging roles of Abl family tyrosine kinases in microbial pathogenesis
    • Backert S, Feller SM, Wessler S. Emerging roles of Abl family tyrosine kinases in microbial pathogenesis. Trends Biochem Sci 2008; 33: 80-90.
    • (2008) Trends Biochem Sci , vol.33 , pp. 80-90
    • Backert, S.1    Feller, S.M.2    Wessler, S.3
  • 9
    • 32944461681 scopus 로고    scopus 로고
    • Abl collaborates with Src family kinases to stimulate actin-based motility of vaccinia virus
    • Newsome TP, Weisswange I, Frischknecht F, Way M. Abl collaborates with Src family kinases to stimulate actin-based motility of vaccinia virus. Cell Microbiol 2006; 8: 233-241.
    • (2006) Cell Microbiol , vol.8 , pp. 233-241
    • Newsome, T.P.1    Weisswange, I.2    Frischknecht, F.3    Way, M.4
  • 10
    • 0036280235 scopus 로고    scopus 로고
    • Bcr-Abl variants: Biological and clinical aspects
    • Advani AS, Pendergast AM. Bcr-Abl variants: biological and clinical aspects. Leuk Res 2002; 26: 713-720.
    • (2002) Leuk Res , vol.26 , pp. 713-720
    • Advani, A.S.1    Pendergast, A.M.2
  • 11
    • 0032778537 scopus 로고    scopus 로고
    • The tyrosine kinase abl-related gene ARG is fused to ETV6 in an AML-M4Eo patient with a t(1;12)(q25;p13): Molecular cloning of both reciprocal transcripts
    • Cazzaniga G, Tosi S, Aloisi A, Giudici G, Daniotti M, Pioltelli P et al. The tyrosine kinase abl-related gene ARG is fused to ETV6 in an AML-M4Eo patient with a t(1;12)(q25;p13): molecular cloning of both reciprocal transcripts. Blood 1999; 94: 4370-4373.
    • (1999) Blood , vol.94 , pp. 4370-4373
    • Cazzaniga, G.1    Tosi, S.2    Aloisi, A.3    Giudici, G.4    Daniotti, M.5    Pioltelli, P.6
  • 12
    • 17544386390 scopus 로고    scopus 로고
    • A new ETV6/TEL partner gene, ARG (ABL-related gene or ABL2), identified in an AML-M3 cell line with a t(1;12)(q25;p13) translocation
    • Iijima Y, Ito T, Oikawa T, Eguchi M, Eguchi-Ishimae M, Kamada N et al. A new ETV6/TEL partner gene, ARG (ABL-related gene or ABL2), identified in an AML-M3 cell line with a t(1;12)(q25;p13) translocation. Blood 2000; 95: 2126-2131.
    • (2000) Blood , vol.95 , pp. 2126-2131
    • Iijima, Y.1    Ito, T.2    Oikawa, T.3    Eguchi, M.4    Eguchi-Ishimae, M.5    Kamada, N.6
  • 13
    • 0025924674 scopus 로고
    • Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins
    • McWhirter JR, Wang JY. Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins. Mol Cell Biol 1991; 11: 1553-1565.
    • (1991) Mol Cell Biol , vol.11 , pp. 1553-1565
    • McWhirter, J.R.1    Wang, J.Y.2
  • 15
    • 36849065315 scopus 로고    scopus 로고
    • Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
    • Rikova K, Guo A, Zeng Q, Possemato A, Yu J, Haack H et al. Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 2007; 131: 1190-1203.
    • (2007) Cell , vol.131 , pp. 1190-1203
    • Rikova, K.1    Guo, A.2    Zeng, Q.3    Possemato, A.4    Yu, J.5    Haack, H.6
  • 16
    • 0037986203 scopus 로고    scopus 로고
    • The selective tyrosine kinase inhibitor, STI571, inhibits growth of anaplastic thyroid cancer cells
    • Podtcheko A, Ohtsuru A, Tsuda S, Namba H, Saenko V, Nakashima M et al. The selective tyrosine kinase inhibitor, STI571, inhibits growth of anaplastic thyroid cancer cells. J Clin Endocrinol Metab 2003; 88: 1889-1896.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1889-1896
    • Podtcheko, A.1    Ohtsuru, A.2    Tsuda, S.3    Namba, H.4    Saenko, V.5    Nakashima, M.6
  • 17
    • 84859610210 scopus 로고    scopus 로고
    • C-Abl and Arg are activated in human primary melanomas promote melanoma cell invasion via distinct pathways and drive metastatic progression
    • Ganguly SS, Fiore LS, Sims JT, Friend JW, Srinivasan D, Thacker MA et al. c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression. Oncogene 2012; 31: 1804-1816.
    • (2012) Oncogene , vol.31 , pp. 1804-1816
    • Ganguly, S.S.1    Fiore, L.S.2    Sims, J.T.3    Friend, J.W.4    Srinivasan, D.5    Thacker, M.A.6
  • 18
    • 0032735234 scopus 로고    scopus 로고
    • Comparative tyrosine-kinase profiles in colorectal cancers: Enhanced arg expression in carcinoma as compared with adenoma and normal mucosa
    • Chen WS, Kung HJ, Yang WK, Lin W. Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa. Int J Cancer 1999; 83: 579-584.
    • (1999) Int J Cancer , vol.83 , pp. 579-584
    • Chen, W.S.1    Kung, H.J.2    Yang, W.K.3    Lin, W.4
  • 20
    • 56149111255 scopus 로고    scopus 로고
    • Cytoplasmic signalling by the c-Abl tyrosine kinase in normal and cancer cells
    • Sirvent A, Benistant C, Roche S. Cytoplasmic signalling by the c-Abl tyrosine kinase in normal and cancer cells. Biol Cell 2008; 100: 617-631.
    • (2008) Biol Cell , vol.100 , pp. 617-631
    • Sirvent, A.1    Benistant, C.2    Roche, S.3
  • 21
    • 33745251071 scopus 로고    scopus 로고
    • Activation of Abl tyrosine kinases promotes invasion of aggressive breast cancer cells
    • Srinivasan D, Plattner R. Activation of Abl tyrosine kinases promotes invasion of aggressive breast cancer cells. Cancer Res 2006; 66: 5648-5655.
    • (2006) Cancer Res , vol.66 , pp. 5648-5655
    • Srinivasan, D.1    Plattner, R.2
  • 22
    • 39149121810 scopus 로고    scopus 로고
    • Aggressive breast cancer cells are dependent on activated Abl kinases for proliferation, anchorage-independent growth and survival
    • Srinivasan D, Sims JT, Plattner R. Aggressive breast cancer cells are dependent on activated Abl kinases for proliferation, anchorage-independent growth and survival. Oncogene 2008; 27: 1095-1105.
    • (2008) Oncogene , vol.27 , pp. 1095-1105
    • Srinivasan, D.1    Sims, J.T.2    Plattner, R.3
  • 23
    • 78650043640 scopus 로고    scopus 로고
    • Abl kinases are required for invadopodia formation and chemokine-induced invasion
    • Smith-Pearson PS, Greuber EK, Yogalingam G, Pendergast AM. Abl kinases are required for invadopodia formation and chemokine-induced invasion. J Biol Chem 2010; 285: 40201-40211.
    • (2010) J Biol Chem , vol.285 , pp. 40201-40211
    • Smith-Pearson, P.S.1    Greuber, E.K.2    Yogalingam, G.3    Pendergast, A.M.4
  • 24
    • 79952203229 scopus 로고    scopus 로고
    • An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invado-podia and breast cancer cell invasion
    • Mader CC, Oser M, Magalhaes MA, Bravo-Cordero JJ, Condeelis J, Koleske AJ et al. An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invado-podia and breast cancer cell invasion. Cancer Res 2011; 71: 1730-1741.
    • (2011) Cancer Res , vol.71 , pp. 1730-1741
    • Mader, C.C.1    Oser, M.2    Magalhaes, M.A.3    Bravo-Cordero, J.J.4    Condeelis, J.5    Koleske, A.J.6
  • 25
    • 28344454000 scopus 로고    scopus 로고
    • Molecular classification and molecular forecasting of breast cancer: Ready for clinical application?
    • Brenton JD, Carey LA, Ahmed AA, Caldas C. Molecular classification and molecular forecasting of breast cancer: ready for clinical application? J Clin Oncol 2005; 23: 7350-7360.
    • (2005) J Clin Oncol , vol.23 , pp. 7350-7360
    • Brenton, J.D.1    Carey, L.A.2    Ahmed, A.A.3    Caldas, C.4
  • 26
    • 0034307318 scopus 로고    scopus 로고
    • The collection of the motile population of cells from a living tumor
    • Wyckoff JB, Segall JE, Condeelis JS. The collection of the motile population of cells from a living tumor. Cancer Res 2000; 60: 5401-5404.
    • (2000) Cancer Res , vol.60 , pp. 5401-5404
    • Wyckoff, J.B.1    Segall, J.E.2    Condeelis, J.S.3
  • 27
    • 73649122504 scopus 로고    scopus 로고
    • Invasion of human breast cancer cells in vivo requires both paracrine and autocrine loops involving the colony-stimulating factor-1 receptor
    • Patsialou A, Wyckoff J, Wang Y, Goswami S, Stanley ER, Condeelis JS. Invasion of human breast cancer cells in vivo requires both paracrine and autocrine loops involving the colony-stimulating factor-1 receptor. Cancer Res 2009; 69: 9498-9506.
    • (2009) Cancer Res , vol.69 , pp. 9498-9506
    • Patsialou, A.1    Wyckoff, J.2    Wang, Y.3    Goswami, S.4    Stanley, E.R.5    Condeelis, J.S.6
  • 28
    • 0034194578 scopus 로고    scopus 로고
    • A critical step in metastasis: In vivo analysis of intravasation at the primary tumor
    • Wyckoff JB, Jones JG, Condeelis JS, Segall JE. A critical step in metastasis: in vivo analysis of intravasation at the primary tumor. Cancer Res 2000; 60: 2504-2511.
    • (2000) Cancer Res , vol.60 , pp. 2504-2511
    • Wyckoff, J.B.1    Jones, J.G.2    Condeelis, J.S.3    Segall, J.E.4
  • 29
    • 34147220392 scopus 로고    scopus 로고
    • Mediators of vascular remodelling co-opted for sequential steps in lung metastasis
    • Gupta GP, Nguyen DX, Chiang AC, Bos PD, Kim JY, Nadal C et al. Mediators of vascular remodelling co-opted for sequential steps in lung metastasis. Nature 2007; 446: 765-770.
    • (2007) Nature , vol.446 , pp. 765-770
    • Gupta, G.P.1    Nguyen, D.X.2    Chiang, A.C.3    Bos, P.D.4    Kim, J.Y.5    Nadal, C.6
  • 31
    • 9244222742 scopus 로고    scopus 로고
    • Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors
    • Wang W, Goswami S, Lapidus K, Wells AL, Wyckoff JB, Sahai E et al. Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors. Cancer Res 2004; 64: 8585-8594.
    • (2004) Cancer Res , vol.64 , pp. 8585-8594
    • Wang, W.1    Goswami, S.2    Lapidus, K.3    Wells, A.L.4    Wyckoff, J.B.5    Sahai, E.6
  • 32
    • 34248586312 scopus 로고    scopus 로고
    • Coordinated regulation of pathways for enhanced cell motility and chemotaxis is conserved in rat and mouse mammary tumors
    • Wang W, Wyckoff JB, Goswami S, Wang Y, Sidani M, Segall JE et al. Coordinated regulation of pathways for enhanced cell motility and chemotaxis is conserved in rat and mouse mammary tumors. Cancer Res 2007; 67: 3505-3511.
    • (2007) Cancer Res , vol.67 , pp. 3505-3511
    • Wang, W.1    Wyckoff, J.B.2    Goswami, S.3    Wang, Y.4    Sidani, M.5    Segall, J.E.6
  • 36
    • 72749120841 scopus 로고    scopus 로고
    • Activated Abl kinase inhibits oncogenic transforming growth factor-beta signaling and tumorigenesis in mammary tumors
    • Allington TM, Galliher-Beckley AJ, Schiemann WP. Activated Abl kinase inhibits oncogenic transforming growth factor-beta signaling and tumorigenesis in mammary tumors. FASEB J 2009; 23: 4231-4243.
    • (2009) FASEB J , vol.23 , pp. 4231-4243
    • Allington, T.M.1    Galliher-Beckley, A.J.2    Schiemann, W.P.3
  • 37
    • 79960138692 scopus 로고    scopus 로고
    • Effect of very small tumor size on cancer-specific mortality in node-positive breast cancer
    • Wo JY, Chen K, Neville BA, Lin NU, Punglia RS. Effect of very small tumor size on cancer-specific mortality in node-positive breast cancer. J Clin Oncol 2011; 29: 2619-2627.
    • (2011) J Clin Oncol , vol.29 , pp. 2619-2627
    • Wo, J.Y.1    Chen, K.2    Neville, B.A.3    Lin, N.U.4    Punglia, R.S.5
  • 38
    • 0028233970 scopus 로고
    • The nuclear tyrosine kinase c-Abl negatively regulates cell growth
    • Sawyers CL, McLaughlin J, Goga A, Havlik M, Witte O. The nuclear tyrosine kinase c-Abl negatively regulates cell growth. Cell 1994; 77: 121-131.
    • (1994) Cell , vol.77 , pp. 121-131
    • Sawyers, C.L.1    McLaughlin, J.2    Goga, A.3    Havlik, M.4    Witte, O.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.