The role of 70-kDa heat shock protein in dDAVP-induced AQP2 trafficking in kidney collecting duct cells

American Journal of Physiology - Renal Physiology

Volumn 304, Issue 7, 2013, Pages

  Park, Eui Jung ^a   Lim, Jung Suk ^a   Jung, Hyun Jun ^a   Kim, Eunjung ^a   Han, Ki Hwan ^b   Kwon, Tae Hwan ^a  

^a Kyungpook National University School of Medicine   (South Korea)

^b Ewha Womans University School of Medicine   (South Korea)

Author keywords

Aquaporin; Collecting duct; Heat shock protein; Phosphorylation; Vasopressin

Indexed keywords

AQUAPORIN 2; DESMOPRESSIN; FORSKOLIN; HEAT SHOCK PROTEIN 70; ARGIPRESSIN[1 DEAMINO]; HSPA1B PROTEIN, RAT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; BIOTINYLATION; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; DNA FLANKING REGION; GENE; GENETIC TRANSFECTION; IMMUNOBLOTTING; KIDNEY CELL; KIDNEY COLLECTING TUBULE; LUMINESCENCE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; URINE OSMOLALITY; URINE VOLUME; WATER DEPRIVATION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECT; HYPOKALEMIA; METABOLISM; MICTURITION; OSMOLARITY; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN TRANSPORT;

ANIMALS; AQUAPORIN 2; BINDING SITES; CELL MEMBRANE; CELLS, CULTURED; DEAMINO ARGININE VASOPRESSIN; HSP70 HEAT-SHOCK PROTEINS; HYPOKALEMIA; KIDNEY TUBULES, COLLECTING; MALE; OSMOLAR CONCENTRATION; PHOSPHORYLATION; PROTEIN TRANSPORT; RATS; URINATION; WATER DEPRIVATION;

MLCS; MLOWN;

EID: 84878236750     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00469.2012     Document Type: Article

References (43)

1. Akcetin Z, Pregla R, Darmer D, Heynemann H, Haerting J, Bromme HJ, Holtz J. Differential expression of heat shock proteins 70-1 and 70-2 mRNA after ischemia-reperfusion injury of rat kidney. Urol Res 27: 306-311, 1999.
2. Boone M, Deen PM. Physiology and pathophysiology of the vasopressin-regulated renal water reabsorption. Pflügers Arch 456: 1005-1024, 2008.
3. Christensen BM, Zelenina M, Aperia A, Nielsen S. Localization and regulation of PKA-phosphorylated AQP2 in response to V2-receptor agonist/antagonist treatment. Am J Physiol Renal Physiol 278: F29-F42, 2000.
4. Christensen S, Kusano E, Yusufi AN, Murayama N, Dousa TP. Pathogenesis of nephrogenic diabetes insipidus due to chronic administration of lithium in rats. J Clin Invest 75: 1869-1879, 1985.
5. Dihazi H, Asif AR, Agarwal NK, Doncheva Y, Muller GA. Proteomic analysis of cellular response to osmotic stress in thick ascending limb of Henle's loop (TALH) cells. Mol Cell Proteomics 4: 1445-1458, 2005.
6. Dudeja V, Vickers SM, Saluja AK. The role of heat shock proteins in gastrointestinal diseases. Gut 58: 1000-1009, 2009.
7. Eisenberg E, Greene LE. Multiple roles of auxilin and hsc70 in clathrin-mediated endocytosis. Traffic 8: 640-646, 2007.
8. Frokiaer J, Marples D, Valtin H, Morris JF, Knepper MA, Nielsen S. Low aquaporin-2 levels in polyuric DI +/+ severe mice with constitu-tively high cAMP-phosphodiesterase activity. Am J Physiol Renal Physiol 276: F179-F190, 1999.
9. Fushimi K, Sasaki S, Marumo F. Phosphorylation of serine 256 is required for cAMP-dependent regulatory exocytosis of the aquaporin-2 water channel. J Biol Chem 272: 14800-14804, 1997.
10. Gabai VL, Yaglom JA, Volloch V, Meriin AB, Force T, Koutroumanis M, Massie B, Mosser DD, Sherman MY. Hsp72-mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell death. Mol Cell Biol 20: 6826-6836, 2000.
11. Han KH, Lee HW, Handlogten ME, Bishop JM, Levi M, Kim J, Verlander JW, Weiner ID. Effect of hypokalemia on renal expression of the ammonia transporter family members, Rh B glycoprotein and Rh C glycoprotein, in the rat kidney. Am J Physiol Renal Physiol 301: F823-F832, 2011.
12. Hartl FU, Hayer-Hartl M. Molecular chaperones in the cytosol: from nascent chain to folded protein. Science 295: 1852-1858, 2002.
13. Hoffert JD, Chou CL, Knepper MA. Aquaporin-2 in the "-omics" era. J Biol Chem 284: 14683-14687, 2009.
14. Homma S, Gapstur SM, Coffey A, Valtin H, Dousa TP. Role of cAMP-phosphodiesterase isozymes in pathogenesis of murine nephrogenic diabetes insipidus. Am J Physiol Renal Fluid Electrolyte Physiol 261: F345-F353, 1991.
15. Jung HJ, Lim JS, Choi HJ, Lee MS, Kim JH, Kim SY, Kim S, Kim E, Kwon TH. Vasopressin V2R-targeting peptide carrier mediates siRNA delivery into collecting duct cells. PLoS One 7: e40010, 2012.
16. Jung HJ, Park JY, Jeon HS, Kwon TH. Aquaporin-5: a marker protein for proliferation and migration of human breast cancer cells. PLoS One 6: e28492, 2011.
17. Kim HY, Choi HJ, Lim JS, Park EJ, Jung HJ, Lee YJ, Kim SY, Kwon TH. Emerging role of Akt substrate protein AS160 in the regulation of AQP2 translocation. Am J Physiol Renal Physiol 301: F151-F161, 2011.
18. Kwon TH, Hager H, Nejsum LN, Andersen ML, Frokiaer J, Nielsen S. Physiology and pathophysiology of renal aquaporins. Semin Nephrol 21: 231-238, 2001.
19. + transporters in rats with lithium-induced NDI. Am J Physiol Renal Physiol 279: F552-F564, 2000.
20. Kwon TH, Nielsen J, Moller HB, Fenton RA, Nielsen S, Frokiaer J. Aquaporins in the kidney. Handb Exp Pharmacol 95-132, 2009.
21. Lee YJ, Lee JE, Choi HJ, Lim JS, Jung HJ, Baek MC, Frokiaer J, Nielsen S, Kwon TH. E3 ubiquitin-protein ligases in rat kidney collecting duct: response to vasopressin stimulation and withdrawal. Am J Physiol Renal Physiol 301: F883-F896, 2011.
22. Lu HA, Sun TX, Matsuzaki T, Yi XH, Eswara J, Bouley R, McKee M, Brown D. Heat shock protein 70 interacts with aquaporin-2 and regulates its trafficking. J Biol Chem 282: 28721-28732, 2007.
23. Marples D, Frokiaer J, Dorup J, Knepper MA, Nielsen S. Hypokal-emia-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla and cortex. J Clin Invest 97: 1960-1968, 1996.
24. Mayer MP, Bukau B. Hsp70 chaperones: cellular functions and molecular mechanism. Cell Mol Life Sci 62: 670-684, 2005.
25. Meimaridou E, Gooljar SB, Ramnarace N, Anthonypillai L, Clark AJ, Chapple JP. The cytosolic chaperone Hsc70 promotes traffic to the cell surface of intracellular retained melanocortin-4 receptor mutants. Mol Endocrinol 25: 1650-1660, 2011.
26. Moeller HB, Fenton RA. Cell biology of vasopressin-regulated aqua-porin-2 trafficking. Pflügers Arch 464: 133-144, 2012.
27. Nedvetsky PI, Tamma G, Beulshausen S, Valenti G, Rosenthal W, Klussmann E. Regulation of aquaporin-2 trafficking. Handb Exp Pharmacol 133-157, 2009.
28. Nielsen J, Kwon TH, Christensen BM, Frokiaer J, Nielsen S. Dysregu-lation of renal aquaporins and epithelial sodium channel in lithium-induced nephrogenic diabetes insipidus. Semin Nephrol 28: 227-244, 2008.
29. Nielsen S, Frokiaer J, Marples D, Kwon TH, Agre P, Knepper MA. Aquaporins in the kidney: from molecules to medicine. Physiol Rev 82: 205-244, 2002.
30. Pratt WB, Toft DO. Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery. Exp Biol Med (Maywood) 228: 111-133, 2003.
31. Promeneur D, Kwon TH, Frokiaer J, Knepper MA, Nielsen S. Vaso-pressin V2-receptor-dependent regulation of AQP2 expression in Brattle-boro rats. Am J Physiol Renal Physiol 279: F370-F382, 2000.
32. Rieg T, Tang T, Murray F, Schroth J, Insel PA, Fenton RA, Hammond HK, Vallon V. Adenylate cyclase 6 determines cAMP formation and aquaporin-2 phosphorylation and trafficking in inner medulla. J Am Soc Nephrol 21: 2059-2068, 2010.
33. Rohde M, Daugaard M, Jensen MH, Helin K, Nylandsted J, Jaattela M. Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms. Genes Dev 19: 570-582, 2005.
34. Rojek A, Fuchtbauer EM, Kwon TH, Frokiaer J, Nielsen S. Severe urinary concentrating defect in renal collecting duct-selective AQP2 conditional-knockout mice. Proc Natl Acad Sci USA 103: 6037-6042, 2006.
35. Schlecht R, Erbse AH, Bukau B, Mayer MP. Mechanics of Hsp70 chaperones enables differential interaction with client proteins. Nat Struct Mol Biol 18: 345-351, 2011.
36. Tamma G, Procino G, Mola MG, Svelto M, Valenti G. Functional involvement of Annexin-2 in cAMP induced AQP2 trafficking. Pflügers Arch 456: 729-736, 2008.
37. Valenti G, Procino G, Tamma G, Carmosino M, Svelto M. Aquaporin 2 trafficking. Endocrinology 146: 5063-5070, 2005.
38. Wang W, Li C, Kwon TH, Knepper MA, Frokiaer J, Nielsen S. AQP3, p-AQP2, and AQP2 expression is reduced in polyuric rats with hypercal-cemia: prevention by cAMP-PDE inhibitors. Am J Physiol Renal Physiol 283: F1313-F1325, 2002.
39. Wang Z, Gall JM, Bonegio RG, Havasi A, Hunt CR, Sherman MY, Schwartz JH, Borkan SC. Induction of heat shock protein 70 inhibits ischemic renal injury. Kidney Int 79: 861-870, 2011.
40. Woo SK, Kwon HM. Adaptation of kidney medulla to hypertonicity: role of the transcription factor TonEBP. Int Rev Cytol 215: 189-202, 2002.
41. Woo SK, Lee SD, Na KY, Park WK, Kwon HM. TonEBP/NFAT5 stimulates transcription of HSP70 in response to hypertonicity. Mol Cell Biol 22: 5753-5760, 2002.
42. Yasui M, Zelenin SM, Celsi G, Aperia A. Adenylate cyclase-coupled vasopressin receptor activates AQP2 promoter via a dual effect on CRE and AP1 elements. Am J Physiol Renal Physiol 272: F443-F450, 1997.
43. Zwang NA, Hoffert JD, Pisitkun T, Moeller HB, Fenton RA, Knepper MA. Identification of phosphorylation-dependent binding partners of aquaporin-2 using protein mass spectrometry. J Proteome Res 8: 1540-1554, 2009.