Preservation of the metabolic rate of oxygen in preterm infants during indomethacin therapy for closure of the ductus arteriosus

Pediatric Research

Volumn 73, Issue 6, 2013, Pages 713-718

  Arora, Rohit ^a   Ridha, Mustafa ^a,b   Lee, David S C ^a   Elliott, Jonathan ^a,b   Rosenberg, Herschel C ^a   Diop, Mamadou ^a,b   Lee, Ting Yim ^a,b,c   St Lawrence, Keith ^a,b  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^c ROBARTS RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INDOCYANINE GREEN; INDOMETACIN;

ARTERIAL OXYGEN SATURATION; ARTICLE; BIRTH WEIGHT; BRAIN BLOOD FLOW; CEREBRAL METABOLIC RATE OF OXYGEN; CLINICAL ARTICLE; DRUG EFFECT; END TIDAL CARBON DIOXIDE TENSION; FEMALE; GESTATIONAL AGE; HEART RATE; HUMAN; MALE; MEAN ARTERIAL PRESSURE; NEWBORN; OXYGEN EXTRACTION FRACTION; PATENT DUCTUS ARTERIOSUS; PREMATURITY; PRIORITY JOURNAL;

DUCTUS ARTERIOSUS, PATENT; FEMALE; HUMANS; INDOMETHACIN; INFANT, NEWBORN; INFANT, PREMATURE; MALE; OXYGEN;

EID: 84878190476     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1038/pr.2013.53     Document Type: Article

References (40)

1. The Vermont-Oxford Trials Network: Very low birth weight outcomes for 1990. Investigators of the Vermont-Oxford Trials Network Database Project. Pediatrics 1993;91:540-5
2. Ellison RC, Peckham GJ, Lang P, et al. Evaluation of the preterm infant for patent ductus arteriosus. Pediatrics 1983;71:364-72
3. Antonucci R, Bassareo P, Zaffanello M, Pusceddu M, Fanos V. Patent ductus arteriosus in the preterm infant: New insights into pathogenesis and clinical management. J Matern Fetal Neonatal Med 2010;23:SUPPL 3:34-7
4. Laughon MM, Simmons MA, Bose CL. Patency of the ductus arteriosus in the premature infant: Is it pathologic? Should it be treated? Curr Opin Pediatr 2004;16:146-51
5. Lemmers PM, Toet MC, van Bel F. Impact of patent ductus arteriosus and subsequent therapy with indomethacin on cerebral oxygenation in preterm infants. Pediatrics 2008;121:142-7
6. Cooke L, Steer P, Woodgate P. Indomethacin for asymptomatic patent ductus arteriosus in preterm infants. Cochrane Database Syst Rev 2003;2:CD003745
7. Ohlsson A, Walia R, Shah SS. Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants. Cochrane Database Syst Rev 2010;1:CD003481
8. Thomas RL, Parker GC, Van Overmeire B, Aranda JV. A meta-Analysis of ibuprofen versus indomethacin for closure of patent ductus arteriosus. Eur J Pediatr 2005;164:135-40
9. Pryds O, Greisen G, Johansen KH. Indomethacin and cerebral blood flow in premature infants treated for patent ductus arteriosus. Eur J Pediatr 1988;147:315-6
10. Patel J, Roberts I, Azzopardi D, Hamilton P, Edwards AD. Randomized double-blind controlled trial comparing the effects of ibuprofen with indomethacin on cerebral hemodynamics in preterm infants with patent ductus arteriosus. Pediatr Res 2000;47:36-42
11. Edwards AD, Wyatt JS, Richardson C, et al. Effects of indomethacin on cerebral haemodynamics in very preterm infants. Lancet 1990;335: 1491-5
12. Evans DH, Levene MI, Archer LN. The effect of indomethacin on cerebral blood-flow velocity in premature infants. Dev Med Child Neurol 1987;29:776-82
13. Ohlsson A, Bottu J, Govan J, Ryan ML, Fong K, Myhr T. Effect of indomethacin on cerebral blood flow velocities in very low birth weight neonates with a patent ductus arteriosus. Dev Pharmacol Ther 1993;20:100-6
14. Keating P, Verhagen E, van Hoften J, ter Horst H, Bos AF. Effect of indomethacin infused over 30 minutes on cerebral fractional tissue oxygen extraction in preterm newborns with a patent ductus arteriosus. Neonatology 2010;98:232-7
15. Garner RS, Miller C, Burchfield DJ. Prophylactic indomethacin infusion increases fractional cerebral oxygen extraction in ELBW neonates. J Perinatol 2012;32:695-8
16. Mosca F, Bray M, Lattanzio M, Fumagalli M, Tosetto C. Comparative evaluation of the effects of indomethacin and ibuprofen on cerebral perfusion and oxygenation in preterm infants with patent ductus arteriosus. J Pediatr 1997;131:549-54
17. McCormick DC, Edwards AD, Brown GC, et al. Effect of indomethacin on cerebral oxidized cytochrome oxidase in preterm infants. Pediatr Res 1993;33:603-8
18. Liem KD, Hopman JC, Kollée LA, Oeseburg B. Effects of repeated indomethacin administration on cerebral oxygenation and haemodynamics in preterm infants: Combined near infrared spectrophotometry and Doppler ultrasound study. Eur J Pediatr 1994;153:504-9
19. Elwell CE, Henty JR, Leung TS, et al. Measurement of CMRO2 in neonates undergoing intensive care using near infrared spectroscopy. Adv Exp Med Biol 2005;566:263-8
20. Kissack CM, Garr R, Wardle SP, Weindling AM. Cerebral fractional oxygen extraction is inversely correlated with oxygen delivery in the sick, newborn, preterm infant. J Cereb Blood Flow Metab 2005;25:545-53
21. Yoxall CW, Weindling AM. Measurement of cerebral oxygen consumption in the human neonate using near infrared spectroscopy: Cerebral oxygen consumption increases with advancing gestational age. Pediatr Res 1998;44:283-90
22. Brown DW, Picot PA, Naeini JG, Springett R, Delpy DT, Lee TY. Quantitative near infrared spectroscopy measurement of cerebral hemodynamics in newborn piglets. Pediatr Res 2002;51:564-70
23. Patel J, Marks K, Roberts I, Azzopardi D, Edwards AD. Measurement of cerebral blood flow in newborn infants using near infrared spectroscopy with indocyanine green. Pediatr Res 1998;43:34-9
24. Garski TR, Staller BJ, Hepner G, Banka VS, Finney RA Jr. Adverse reactions after administration of indocyanine green. JAMA 1978;240:635
25. Tichauer KM, Hadway JA, Lee TY, St Lawrence K. Measurement of cerebral oxidative metabolism with near-infrared spectroscopy: A validation study. J Cereb Blood Flow Metab 2006;26:722-30
26. König W, Brom J, Schönfeld W, Knöller J, Stüning M. Effect of tenoxicam and indomethacin on the release of histamine, prostaglandin E2 and leukotrienes from various cells. Arzneimittelforschung 1987;37:296-9
27. Docherty JC, Wilson TW. Indomethacin increases the formation of lipoxygenase products in calcium ionophore stimulated human neutrophils. Biochem Biophys Res Commun 1987;148:534-8
28. Görk AS, Ehrenkranz RA, Bracken MB. Continuous infusion versus intermittent bolus doses of indomethacin for patent ductus arteriosus closure in symptomatic preterm infants. Cochrane Database Syst Rev 2008;1:CD006071
29. Hammerman C, Glaser J, Schimmel MS, Ferber B, Kaplan M, Eidelman AI. Continuous versus multiple rapid infusions of indomethacin: Effects on cerebral blood flow velocity. Pediatrics 1995;95:244-8
30. Kondo M, Kunikata T, Okazaki K, Yasuda S, Isobe K, Itoh S. Relation between infusion rate of indomethacin and cerebral blood flow velocity. Pediatr Int 2010;52:616-21
31. Flisberg A, Kjellmer I, Löfhede J, et al. Does indomethacin for closure of patent ductus arteriosus affect cerebral function? Acta Paediatr 2010;99:1493-7
32. Pourcyrous M, Leffler CW, Bada HS, Korones SB, Busija DW. Cerebral blood flow responses to indomethacin in awake newborn pigs. Pediatr Res 1994;35:565-70
33. Leffler CW, Busija DW, Beasley DG. Effect of therapeutic dose of indomethacin on the cerebral circulation of newborn pigs. Pediatr Res 1987;21:188-92
34. Brown DW, Lee D, Kumaran VS, Lee TY. Age-dependent cerebral hemodynamic effects of indomethacin in the newborn piglet. J Appl Physiol 2004;97:1880-7
35. Greisen G. Cerebral blood flow in preterm infants during the first week of life. Acta Paediatr Scand 1986;75:43-51
36. Leung TS, Aladangady N, Elwell CE, Delpy DT, Costeloe K. A new method for the measurement of cerebral blood volume and total circulating blood volume using near infrared spatially resolved spectroscopy and indocyanine green: Application and validation in neonates. Pediatr Res 2004;55:134-41
37. Diop M, Verdecchia K, Lee TY, St Lawrence K. Calibration of diffuse correlation spectroscopy with a time-resolved near-infrared technique to yield absolute cerebral blood flow measurements. Biomed Opt Express 2011;2:2068-81
38. Schmidt B, Davis P, Moddemann D, et al.; Trial of Indomethacin Prophylaxis in Preterms Investigators. Long-Term effects of indomethacin prophylaxis in extremely-low-birth-weight infants. N Engl J Med 2001;344:1966-72
39. Matcher SJ, Cope M, Delpy DT. Use of the water absorption spectrum to quantify tissue chromophore concentration changes in near-infrared spectroscopy. Phys Med Biol 1994;39:177-96
40. Zierler KL. Equations for measuring blood flow by external monitoring of radioisotopes. Circ Res 1965;16:309-21