Multicenter Italian experience in liver transplantation for hepatocellular carcinoma in HIV-infected patients

Oncologist

Volumn 18, Issue 5, 2013, Pages 592-599

  Di Benedetto, Fabrizio ^a   Tarantino, Giuseppe ^a   Ercolani, Giorgio ^b   Baccarani, Umberto ^c   Montalti, Roberto ^a   De Ruvo, Nicola ^a   Berretta, Massimiliano ^e   Adani, Gian Luigi ^c   Zanello, Matteo ^b   Tavio, Marcello ^d   Cautero, Nicola ^a   Tirelli, Umberto ^e   Pinna, Antonio D ^b   Gerunda, Giorgio E ^a   Guaraldi, Giovanni ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c UNIVERSITY OF UDINE   (Italy)

^d UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^e CENTRO DI RIFERIMENTO ONCOLOGICO   (Italy)

Author keywords

HCV; Hepatocellular carcinoma; HIV; Liver transplantation

Indexed keywords

ALPHA FETOPROTEIN; CYCLOSPORIN; DOXORUBICIN; RAPAMYCIN; SORAFENIB; STEROID; TACROLIMUS;

ADRENAL CORTEX CARCINOMA; ADULT; AGED; ANUS CARCINOMA; ARTICLE; BILE DUCT RECONSTRUCTION; BLEEDING; CHEMOEMBOLIZATION; CHRONIC HEPATITIS; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DEATH; ECHOGRAPHY; END STAGE LIVER DISEASE; FEMALE; FOLLOW UP; HEART FAILURE; HEPATITIS B; HEPATITIS C; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HISTOLOGY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER RESECTION; LIVER TRANSPLANTATION; MALE; MIXED INFECTION; MULTICENTER STUDY; NECROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; OVERALL SURVIVAL; POSTOPERATIVE CARE; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; RADIOFREQUENCY ABLATION; RECURRENT DISEASE; RETRANSPLANTATION; SEPSIS;

HCV; HEPATOCELLULAR CARCINOMA; HIV; LIVER TRANSPLANTATION;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; FEMALE; FOLLOW-UP STUDIES; HIV INFECTIONS; HIV-1; HUMANS; ITALY; LIVER NEOPLASMS; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 84878171589     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.2012-0255     Document Type: Article

References (29)

1. El-Serag HB. Hepatocellular carcinoma: An epidemiologic view. J Clin Gastroenterol 2002; 35(suppl 2):S72-S78.
2. Weber R, Sabin CA, Friis-Moller N et al. Liverrelated deaths in persons infected with the human immunodeficiency virus: The D:A:D study. Arch Intern Med 2006;166:1632-1641.
3. Berretta M, Garlassi E, Cacopardo B et al. Hepatocellular carcinoma in HIV-infected patients: Check early, treat hard. The Oncologist 2011;16: 1258-1269.
4. Serraino D, Boschini A, Carrieri P et al. Cancer risk among men with, or at risk of, HIV infection in southern Europe. AIDS 2000;14:553-559.
5. Altavilla G, Caputo A, Lanfredi M et al. Enhancement of chemical hepatocarcinogenesis by the HIV-1 tat gene. AmJ Pathol 2000;157:1081-1089.
6. Vogel J, Hinrichs S, Napolitano L et al. Liver cancer in transgenic mice carrying the HIV tat gene. Cancer Res 1991;51:6686-6690.
7. Corallini A, Altavilla G, Pozzi L et al. Systemic expression of HIV-1 tat gene in transgenic mice induces endothelial proliferation and tumors of different histotypes. Cancer Res 1993;53:5569-5575.
8. Berretta M, Cinelli R, Martellotta F et al. Clinical presentation and outcome of colorectal cancer in HIV-positive patients: A clinical case-control study. Onkologie 2009;32:319-324.
9. Marcellin P, Pequignot F, Delarocque-Astagneau E et al. Mortality related to chronic hepatitis B and chronic hepatitis C in France: Evidence for the role of HIV coinfection and alcohol consumption. J Hepatol 2008;48:200-207.
10. Salmon-Ceron D, Rosenthal E, Lewden C et al. Emerging role of hepatocellular carcinoma among liver-related causes of deaths in HIV-infected patients: The French national Mortalité 2005 study. J Hepatol 2009;50:736-745.
11. Rosenthal E, Salmon-Ceron D, Lewden C et al. Liver-related deaths in HIV-infected patients between 1995 and 2005 in the French GERMIVIC Joint Study Group Network (Mortavic 2005 study in collaboration with the Mortalité 2005 survey, ANRS EN19) HIV Med 2009;10:282-289.
12. Blumberg EA, Stock P, and the AST Infectious Diseases Community of Practice. Solid organ transplantation in the HIV-infected patient. Am J Transplant 2009;9(suppl 4):S131-S135.
13. Cooper C, Kanters S, Klein M et al. Liver transplant outcomes in HIV-infected patients: A systematic review and meta-analysis with synthetic cohort. AIDS 2011;25:777-786.
14. Duclos-Vallee JC, Feray C, Sebagh M et al. Survival and recurrence of hepatitis C after liver transplantation in patients coinfected with human immunodeficiency virusandhepatitisCvirus. Hepatology 2008;47:407-417.
15. Vibert E, Duclos-Vallée JC, Ghigna MR et al. Liver transplantation for hepatocellular carcinoma: Theimpactofhumanimmunodeficiencyvirus infection. Hepatology 2011;53:475-482.
16. Di Benedetto F, De Ruvo N, Berretta M et al. Hepatocellular carcinoma inHIVpatients treatedby liver transplantation. Eur J SurgOncol2008;34:422-427.
17. Di Benedetto F, De Ruvo N, Berretta M et al. Don't deny liver transplantation to HIV patients with hepatocellular carcinoma in the highly active antiretroviral therapy era. J Clin Oncol 2006;24: e26-e27.
18. Italian protocol for liver transplantation in HIV-infected patients. Available at http://www.salute.gov.it/imgs/C_17_pubblicazioni_1104_allegato.pdf. Accessed April 23, 2011.
19. Bruix J, Sherman M, Llovet JM et al. Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. J Hepatol 2001;35:421-430.
20. Yao FY, Kerlan RK, Hirose R et al. Excellent outcomefollowing down-staging of hepatocellular carcinoma prior to liver transplantation: An intentionto-treat analysis. Hepatology 2008;48:819-827.
21. Piscaglia F, Gianstefani A, Ravaioli M et al. Criteria for diagnosing benign portal vein thrombosis in the assessment of patients with cirrhosis and hepatocellular carcinoma for liver transplantation. Liver Transpl 2010;16:658-667.
22. Di Benedetto F, Di Sandro S, De Ruvo N et al. Kaposi's sarcoma after liver transplantation. J Cancer Res Clin Oncol. 2008 Jun;134(6):653-658. Epub 2007 Oct 9.
23. Di Benedetto F, Di Sandro S, De Ruvo N et al. First report on a series of HIV patients undergoing rapamycin monotherapy after liver transplantation. Transplantation. 2010 Mar 27;89(6):733-738. doi: 10.1097/TP.0b013e3181c7dcc0.
24. Di Benedetto F, Tarantino G, Montalti R et al. Theimpactofhumanimmunodeficiencyvirus infection in liver transplantation for hepatocellular carcinoma. Hepatology 2011;53:1777-1778.
25. Di Benedetto F, Di Sandro S, De Ruvo N et al. Humanimmunodeficiencyvirusandliver transplantation: Our point of view. Transplant Proc 2008;40: 1965-1971.
26. Guaraldi G, Cocchi S, Motta A et al. Differential dose adjustments of immunosuppressants after resuming boosted versus unboosted HIV-protease inhibitors post liver transplant. AmJ Transplant 2009; 9:2429-2434.
27. Latinovic O, Kuruppu J, Davis C et al. Pharmacotherapy of HIV-1 infection: Focus on CCR5 antagonist maraviroc. Clin Med Ther 2009;1:1497-1510.
28. Heredia A, Gilliam B, Latinovic O, et al. Rapamycin reduces CCR5 density levels on CD4 T cells and this effect results in potentiation of Enfuvirtide (T-20) against R5 HIV-1 in vitro. Antimicrob Agents Chemother 2007;51:2489-2496.
29. Chow WA, Jiang C, Guan M. Anti-HIV drugs for cancer therapeutics: Back to the future? Lancet Oncol 2009;10:61-71.