Substitutions T200A and E227A in the hemagglutinin of pandemic 2009 influenza a virus increase lethality but decrease transmission

Journal of Virology

Volumn 87, Issue 11, 2013, Pages 6507-6511

  Martínez Romero, Carles ^a   de Vries, Erik ^b   Belicha Villanueva, Alan ^a   Mena, Ignacio ^a   Tscherne, Donna M ^a   Gillespie, Virginia L ^a   Albrecht, Randy A ^a   de Haan, Cornelis A M ^b   García Sastre, Adolfo ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

INFLUENZA VIRUS HEMAGGLUTININ;

2009 H1N1 INFLUENZA; AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; FERRET; HISTOPATHOLOGY; HUMAN; HUMAN CELL; INFLUENZA VIRUS A H1N1; LETHALITY; MDCK CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRACHEOBRONCHIAL TREE; VIRUS CELL INTERACTION; VIRUS LOAD; VIRUS PATHOGENESIS; VIRUS REPLICATION; VIRUS TRANSMISSION; WEIGHT REDUCTION;

AMINO ACID SUBSTITUTION; ANIMALS; DOWN-REGULATION; FEMALE; FERRETS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MICE; MICE, INBRED DBA; PANDEMICS; UP-REGULATION; VIRULENCE;

EID: 84878166799     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00262-13     Document Type: Article

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