Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity

Biochimica et Biophysica Acta - General Subjects

Volumn 1830, Issue 8, 2013, Pages 4235-4243

  Stratford, Eva Wessel ^a   Bostad, Monica ^a   Castro, Russell ^a   Skarpen, Ellen ^a   Berg, Kristian ^a   Høgset, Anders ^a,b   Myklebost, Ola ^a,c   Selbo, Pål Kristian ^a,b  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b PCI Biotech AS   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

Cancer stem cell; CD133; Drug delivery; Endosomal escape; Photochemical internalization; Sarcoma

Indexed keywords

CD133 ANTIGEN; MONOCLONAL ANTIBODY; PHOTOSENSITIZING AGENT; RIBOSOME INACTIVATING PROTEIN; SAPORIN; TETRAPHENYLCHLORIN; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER STEM CELL; CARCINOGENICITY; CELL ISOLATION; CELL KILLING; CELL PROLIFERATION; CELL SUBPOPULATION; CELL SURVIVAL; CELL VIABILITY; CELLULAR DISTRIBUTION; COLONY FORMATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG TARGETING; HUMAN; HUMAN CELL; PHOTOCHEMICAL INTERNALIZATION; PRIORITY JOURNAL; PROTEIN BINDING; SARCOMA CELL; TUMOR XENOGRAFT;

ANIMALS; ANTIGENS, CD; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; GLYCOPROTEINS; HUMANS; IMMUNOTOXINS; MICE; MICE, SCID; NEOPLASTIC STEM CELLS; PEPTIDES; PHOTOCHEMISTRY; PHOTOSENSITIZING AGENTS; SARCOMA; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84878151456     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.04.033     Document Type: Article

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