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Volumn 50, Issue 5, 2013, Pages 529-536

Effectiveness of omalizumab in severe allergic asthma: A retrospective UK real-world study

Author keywords

Anti asthmatic agents; Hospital resource use; Monoclonal antibodies; Observational study; Quality of life

Indexed keywords

CORTICOSTEROID; IMMUNOSUPPRESSIVE AGENT; METHOTREXATE; MONTELUKAST; OMALIZUMAB;

EID: 84878134498     PISSN: 02770903     EISSN: 15324303     Source Type: Journal    
DOI: 10.3109/02770903.2013.790419     Document Type: Article
Times cited : (100)

References (31)
  • 2
    • 20044362008 scopus 로고    scopus 로고
    • Benefits of omalizumab as add on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATE
    • Humbert M, Beasley R, Ayres J, Slavin R, Hébert J, Bousquet J, Beeh K-M, Ramos S, Canonica G W, Hedgecock S, Fox H, Blogg M, Surrey K. Benefits of omalizumab as add on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATE. Allergy 2005; 60:309-316
    • (2005) Allergy , vol.60 , pp. 309-316
    • Humbert, M.1    Beasley, R.2    Ayres, J.3    Slavin, R.4    Hébert, J.5    Bousquet, J.6    Beeh, K.-M.7    Ramos, S.8    Canonica, G.W.9    Hedgecock, S.10    Fox, H.11    Blogg, M.12    Surrey, K.13
  • 3
    • 69949146665 scopus 로고    scopus 로고
    • Omalizumab for asthma: Pharmacology and clinical profile
    • Fritscher L, Chapman KR. Omalizumab for asthma: Pharmacology and clinical profile. Expert Rev Resp Med 2009; 3(2):119-127
    • (2009) Expert Rev Resp Med , vol.3 , Issue.2 , pp. 119-127
    • Fritscher, L.1    Chapman, K.R.2
  • 4
    • 20044368243 scopus 로고    scopus 로고
    • The effect of treatment with omalizumab, an anti-IgE antibody, on asthma exacerbations and emergency medical visits in patients with severe persistent asthma
    • Bousquet J, Cabrera P, Berkman N, Buhl R, Holgate S, Wenzel S, Fox H, Hedgecock S, Blogg M, Cioppa GD. The effect of treatment with omalizumab, an anti-IgE antibody, on asthma exacerbations and emergency medical visits in patients with severe persistent asthma. Allergy 2005; 60:302-308
    • (2005) Allergy , vol.60 , pp. 302-308
    • Bousquet, J.1    Cabrera, P.2    Berkman, N.3    Buhl, R.4    Holgate, S.5    Wenzel, S.6    Fox, H.7    Hedgecock, S.8    Blogg, M.9    Cioppa, G.D.10
  • 5
    • 84878118098 scopus 로고    scopus 로고
    • Scottish Medicines Consortium Xolair®) (No. 259/06). Available at: Accessed April 24 2013
    • Scottish Medicines Consortium. Omalizumab 150mg powder and solvent for injection (Xolair®) (No. 259/06). 2007. Available at: Http://www. scottishmedicines.org.uk/SMC-Advice/Advice/Omalizumab- Xolair-/omalizumab-150mg- powder-and-solvent-for-injection- Xolair-1. Accessed April 24, 2013
    • (2007) Omalizumab 150mg Powder And Solvent For Injection
  • 6
    • 84878159908 scopus 로고    scopus 로고
    • Scottish Medicines Consortium Xolair®) (No: 611/10). 2010 Product Update Available at: Accessed April
    • Scottish Medicines Consortium. Omalizumab 150 mg powder and solvent for solution for injection (Xolair®) (No: 611/10). 2010 Product Update. Available at: Http://www.scottishmedicines.org.uk/files/OmalizumabXolair- Abbreviated-Mar2010.pdf. Accessed April 24, 2013
    • (2013) Omalizumab 150 mg Powder And Solvent For Solution For Injection , vol.24
  • 8
    • 0022596984 scopus 로고
    • Systemic steroids in chronic severe asthma
    • Lewis LD, Cochrane GM. Systemic steroids in chronic severe asthma. Br Med J (Clin Res Ed) 1986; 292:1289-1290
    • (1986) Br Med J (Clin Res Ed , vol.292 , pp. 1289-1290
    • Lewis, L.D.1    Cochrane, G.M.2
  • 9
    • 84944364661 scopus 로고    scopus 로고
    • Office of health economics
    • Office of Health Economics, London 2003
    • Yuen P. Office of Health Economics. Compendium of Health Statistics 2003-2004, Office of Health Economics, London 2003
    • (2003) Compendium of Health Statistics
    • Yuen, P.1
  • 11
    • 36448986847 scopus 로고    scopus 로고
    • Effectiveness of omalizumab (Xolair®) in the first patients treated in real-life practice in France
    • Molimard M, de Blay F, Didier A, Le Gros V. Effectiveness of omalizumab (Xolair®) in the first patients treated in real-life practice in France. Respir Med 2008; 102:71-76
    • (2008) Respir Med , vol.102 , pp. 71-76
    • Molimard, M.1    De Blay, F.2    Didier, A.3    Le Gros, V.4
  • 13
    • 70349542893 scopus 로고    scopus 로고
    • Omalizumab in patients with severe persistent allergic asthma in a reallife setting in Germany
    • Korn S, Thielen A, Seyfried S, Taube C, Kornmann O, Buhl R. Omalizumab in patients with severe persistent allergic asthma in a reallife setting in Germany. Respir Med 2009; 103:1725-1731
    • (2009) Respir Med , vol.103 , pp. 1725-1731
    • Korn, S.1    Thielen, A.2    Seyfried, S.3    Taube, C.4    Kornmann, O.5    Buhl, R.6
  • 15
    • 84863980228 scopus 로고    scopus 로고
    • Longitudinal changes in asthma control with Omalizumab: 2 year interim data from the EXCELS study
    • Eisner MD, Zazzali JL, Miller MK, Bradley MS, Schatz M. Longitudinal changes in asthma control with Omalizumab: 2 year interim data from the EXCELS study. J Asthma 2012; 49:642-648
    • (2012) J Asthma , vol.49 , pp. 642-648
    • Eisner, M.D.1    Zazzali, J.L.2    Miller, M.K.3    Bradley, M.S.4    Schatz, M.5
  • 16
    • 84866354219 scopus 로고    scopus 로고
    • 36 month study on the cost/utility of add-on omalizumab in persistent difficult-to-treat atopic7asthma in Italy
    • Dal Negro RW, Tognella S, Pradelli LA. 36 month study on the cost/utility of add-on omalizumab in persistent difficult-to-treat atopic7asthma in Italy. J Asthma 2012; 49:843-848
    • (2012) J Asthma , vol.49 , pp. 843-848
    • Dal Negro, R.W.1    Tognella, S.2    Pradelli, L.A.3
  • 17
    • 67649324077 scopus 로고    scopus 로고
    • A UK survey of oral corticosteroid use in patients treated with omalizumab
    • Abstract P91
    • Niven R, McBryan D. A UK survey of oral corticosteroid use in patients treated with omalizumab. Thorax 2007; 62(suppl. 3):A98 (Abstract P91).
    • (2007) Thorax , vol.62 , Issue.SUPPL. 3
    • Niven, R.1    McBryan, D.2
  • 18
    • 84878116996 scopus 로고    scopus 로고
    • Real-life effectiveness of omalizumab in patientswith severe persistent allergic (IgE-mediated) asthma at a single UK hospital
    • Simons S, Regan K, Aziz A, Saralaya D. Real-life effectiveness of omalizumab in patientswith severe persistent allergic (IgE-mediated) asthma at a single UK hospital. Am J Respir Crit Care Med 2010; 181:A1336
    • (2010) Am J Respir Crit Care Med , Issue.181
    • Simons, S.1    Regan, K.2    Aziz, A.3    Saralaya, D.4
  • 19
    • 84878121281 scopus 로고    scopus 로고
    • Real-life effectiveness of omalizumab in patients with severe persistent allergic (IgE-mediated) asthma at a single UK hospital
    • E1875 (Abstract).
    • Knowles V, Nordstrom M, Britton M. Real-life effectiveness of omalizumab in patients with severe persistent allergic (IgE-mediated) asthma at a single UK hospital. Eur Respir J 2009;34(suppl. 53):315s, E1875 (Abstract).
    • (2009) Eur Respir J , vol.34 , Issue.SUPPL. 53 , pp. 315
    • Knowles, V.1    Nordstrom, M.2    Britton, M.3
  • 20
    • 84878131158 scopus 로고    scopus 로고
    • The effectiveness of omalizumab in severe allergic asthma is comparable in patients selected by NICE or SMC criteria
    • Abstract
    • Gibeon D, Campbell DA, Regan SE, Menzies-Gow A. The effectiveness of omalizumab in severe allergic asthma is comparable in patients selected by NICE or SMC criteria. Am J Respir Crit Care Med 2009; 179:A2812 (Abstract).
    • (2009) Am J Respir Crit Care Med , vol.179
    • Gibeon, D.1    Campbell, D.A.2    Regan, S.E.3    Menzies-Gow, A.4
  • 22
    • 0026543164 scopus 로고
    • Evaluation of impairment of health-related quality of life in asthma: Development of a questionnaire for use in clinical trials
    • Juniper EF, Guyatt GH, Epstein RS, Ferrie PJ, Jaeschke R, Hiller TK. Evaluation of impairment of health-related quality of life in asthma: Development of a questionnaire for use in clinical trials. Thorax 1992; 47:76-83
    • (1992) Thorax , vol.47 , pp. 76-83
    • Juniper, E.F.1    Guyatt, G.H.2    Epstein, R.S.3    Ferrie, P.J.4    Jaeschke, R.5    Hiller, T.K.6
  • 23
    • 25844453682 scopus 로고    scopus 로고
    • Joint Formulary Committee 4th e.d London: BMJ Group and Pharmaceutical Press
    • Joint Formulary Committee. British National Formulary. 64th ed. London: BMJ Group and Pharmaceutical Press, 2012
    • (2012) British National Formulary
  • 28
    • 79961129152 scopus 로고    scopus 로고
    • Therapy with omalizumab for patients with severe allergic asthma improves asthma control and reduces overall healthcare costs
    • Costello RW, Long DAA, Gaine S, Mc Donnell T, Gilmartin JJ, Lane SJ. Therapy with omalizumab for patients with severe allergic asthma improves asthma control and reduces overall healthcare costs. Ir J Med Sci 2011; 180:637-641
    • (2011) Ir J Med Sci , Issue.180 , pp. 637-641
    • Costello, R.W.1    Long, D.A.A.2    Gaine, S.3    Mc Donnell, T.4    Gilmartin, J.J.5    Lane, S.J.6
  • 29
    • 0347623366 scopus 로고    scopus 로고
    • The relationship of sex to asthma prevalence, health care utilization and medications in a large managed care organization
    • Schatz M, Camargo CA Jr. The relationship of sex to asthma prevalence, health care utilization and medications in a large managed care organization. Ann Allergy Asthma Immunol 2003; 91:553-558
    • (2003) Ann Allergy Asthma Immunol , vol.91 , pp. 553-558
    • Schatz, M.1    Camargo Jr., C.A.2
  • 30
    • 77956341586 scopus 로고    scopus 로고
    • Italian real-life experience of omalizumab
    • Cazzola M, Camiciottoli G, Bonavia M, et al. Italian real-life experience of omalizumab. Respir Med 2010; 104:1410-1416
    • (2010) Respir Med , Issue.104 , pp. 1410-1416
    • Cazzola, M.1    Camiciottoli, G.2    Bonavia, M.3


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