-
1
-
-
33750454040
-
A urokinase-activated recombinant anthrax toxin is selectively cytotoxic to many human tumor cell types
-
Abi-Habib R.J., et al. A urokinase-activated recombinant anthrax toxin is selectively cytotoxic to many human tumor cell types. Molecular Cancer Therapeutics 2006, 5(10):2556-2562.
-
(2006)
Molecular Cancer Therapeutics
, vol.5
, Issue.10
, pp. 2556-2562
-
-
Abi-Habib, R.J.1
-
2
-
-
84655162706
-
Treatment of HER2-positive breast cancer: current status and future perspectives
-
Arteaga C.L., et al. Treatment of HER2-positive breast cancer: current status and future perspectives. Nature Reviews Clinical Oncology 2012, 9(1):16-32.
-
(2012)
Nature Reviews Clinical Oncology
, vol.9
, Issue.1
, pp. 16-32
-
-
Arteaga, C.L.1
-
3
-
-
0025281906
-
Overexpression of HER-2/neu is associated with poor survival in advanced epithelial ovarian cancer
-
Berchuck A., et al. Overexpression of HER-2/neu is associated with poor survival in advanced epithelial ovarian cancer. Cancer Research 1990, 50(13):4087-4091.
-
(1990)
Cancer Research
, vol.50
, Issue.13
, pp. 4087-4091
-
-
Berchuck, A.1
-
4
-
-
0035829509
-
Identification of the cellular receptor for anthrax toxin
-
Bradley K.A., et al. Identification of the cellular receptor for anthrax toxin. Nature 2001, 414(6860):225-229.
-
(2001)
Nature
, vol.414
, Issue.6860
, pp. 225-229
-
-
Bradley, K.A.1
-
6
-
-
0014665802
-
Diphtheria toxin subunit active in vitro
-
Collier R.J., Cole H.A. Diphtheria toxin subunit active in vitro. Science 1969, 164(884):1179-1181.
-
(1969)
Science
, vol.164
, Issue.884
, pp. 1179-1181
-
-
Collier, R.J.1
Cole, H.A.2
-
7
-
-
0014202360
-
Effect of diphtheria toxin on protein synthesis: inactivation of one of the transfer factors
-
Collier R.J. Effect of diphtheria toxin on protein synthesis: inactivation of one of the transfer factors. Journal of Molecular Biology 1967, 25(1):83-98.
-
(1967)
Journal of Molecular Biology
, vol.25
, Issue.1
, pp. 83-98
-
-
Collier, R.J.1
-
8
-
-
70350708307
-
Membrane translocation by anthrax toxin
-
Collier R.J. Membrane translocation by anthrax toxin. Molecular Aspects of Medicine 2009, 30(6):413-422.
-
(2009)
Molecular Aspects of Medicine
, vol.30
, Issue.6
, pp. 413-422
-
-
Collier, R.J.1
-
9
-
-
0037076304
-
Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen
-
Cunningham K., et al. Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen. Proceedings of the National Academy of Sciences of the United States of America 2002, 99(10):7049-7053.
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.10
, pp. 7049-7053
-
-
Cunningham, K.1
-
10
-
-
18244414803
-
Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor
-
Duesbery N.S., et al. Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor. Science 1998, 280(5364):734-737.
-
(1998)
Science
, vol.280
, Issue.5364
, pp. 734-737
-
-
Duesbery, N.S.1
-
11
-
-
0035957358
-
Suppression of ras-mediated transformation and inhibition of tumor growth and angiogenesis by anthrax lethal factor, a proteolytic inhibitor of multiple MEK pathways
-
Duesbery N.S., et al. Suppression of ras-mediated transformation and inhibition of tumor growth and angiogenesis by anthrax lethal factor, a proteolytic inhibitor of multiple MEK pathways. Proceedings of the National Academy of Sciences of the United States of America 2001, 98(7):4089-4094.
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.7
, pp. 4089-4094
-
-
Duesbery, N.S.1
-
12
-
-
0023219950
-
RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes
-
Endo Y., Tsurugi K. RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes. The Journal of Biological Chemistry 1987, 262(17):8128-8130.
-
(1987)
The Journal of Biological Chemistry
, vol.262
, Issue.17
, pp. 8128-8130
-
-
Endo, Y.1
Tsurugi, K.2
-
13
-
-
0001776198
-
DAB(389)IL-2 (denileukin diftitox, ONTAK): a new fusion protein technology
-
Foss F.M. DAB(389)IL-2 (denileukin diftitox, ONTAK): a new fusion protein technology. Clinical Lymphoma 2000, 1(Suppl. 1):S27-S31.
-
(2000)
Clinical Lymphoma
, vol.1
, Issue.SUPPL. 1
-
-
Foss, F.M.1
-
15
-
-
0014429772
-
Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis
-
Honjo T., Nishizuka Y., Hayaishi O. Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis. The Journal of Biological Chemistry 1968, 243(12):3553-3555.
-
(1968)
The Journal of Biological Chemistry
, vol.243
, Issue.12
, pp. 3553-3555
-
-
Honjo, T.1
Nishizuka, Y.2
Hayaishi, O.3
-
16
-
-
69349098830
-
The protective antigen component of anthrax toxin forms functional octameric complexes
-
Kintzer A.F., et al. The protective antigen component of anthrax toxin forms functional octameric complexes. Journal of Molecular Biology 2009, 392(3):614-629.
-
(2009)
Journal of Molecular Biology
, vol.392
, Issue.3
, pp. 614-629
-
-
Kintzer, A.F.1
-
17
-
-
0026498189
-
Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin
-
Klimpel K.R., et al. Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin. Proceedings of the National Academy of Sciences of the United States of America 1992, 89(21):10277-10281.
-
(1992)
Proceedings of the National Academy of Sciences of the United States of America
, vol.89
, Issue.21
, pp. 10277-10281
-
-
Klimpel, K.R.1
-
18
-
-
77953359099
-
Multiple molecular mechanisms underlying trastuzumab and lapatinib resistance in JIMT-1 breast cancer cells
-
Köninki K., et al. Multiple molecular mechanisms underlying trastuzumab and lapatinib resistance in JIMT-1 breast cancer cells. Cancer Letters 2010, 294(2):211-219.
-
(2010)
Cancer Letters
, vol.294
, Issue.2
, pp. 211-219
-
-
Köninki, K.1
-
19
-
-
0037022666
-
Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase
-
Koo H.-M., et al. Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase. Proceedings of the National Academy of Sciences of the United States of America 2002, 99(5):3052-3057.
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.5
, pp. 3052-3057
-
-
Koo, H.-M.1
-
20
-
-
4444267311
-
Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation
-
Lacy D.B., et al. Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation. Proceedings of the National Academy of Sciences of the United States of America 2004, 101(36):13147-13151.
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.36
, pp. 13147-13151
-
-
Lacy, D.B.1
-
21
-
-
0000947082
-
Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells
-
Leppla S.H. Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells. Proceedings of the National Academy of Sciences of the United States of America 1982, 79(10):3162-3166.
-
(1982)
Proceedings of the National Academy of Sciences of the United States of America
, vol.79
, Issue.10
, pp. 3162-3166
-
-
Leppla, S.H.1
-
22
-
-
56449129810
-
Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate
-
Lewis Phillips G.D., et al. Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate. Cancer Research 2008, 68(22):9280-9290.
-
(2008)
Cancer Research
, vol.68
, Issue.22
, pp. 9280-9290
-
-
Lewis Phillips, G.D.1
-
23
-
-
0034326255
-
Tumor cell-selective cytotoxicity of matrix metalloproteinase-activated anthrax toxin
-
Liu S., et al. Tumor cell-selective cytotoxicity of matrix metalloproteinase-activated anthrax toxin. Cancer Research 2000, 60(21):6061-6067.
-
(2000)
Cancer Research
, vol.60
, Issue.21
, pp. 6061-6067
-
-
Liu, S.1
-
24
-
-
77953130101
-
Affibody molecules: engineered proteins for therapeutic, diagnostic and biotechnological applications
-
Löfblom J., et al. Affibody molecules: engineered proteins for therapeutic, diagnostic and biotechnological applications. FEBS Letters 2010, 584(12):2670-2680.
-
(2010)
FEBS Letters
, vol.584
, Issue.12
, pp. 2670-2680
-
-
Löfblom, J.1
-
26
-
-
84863449301
-
Changing the receptor specificity of anthrax toxin
-
Mechaly A., McCluskey A.J., Collier R.J. Changing the receptor specificity of anthrax toxin. mBio 2012, 3(3). pp. e00088-12, Available at:. http://mbio.asm.org/content/3/3/e00088-12.
-
(2012)
mBio
, vol.3
, Issue.3
-
-
Mechaly, A.1
McCluskey, A.J.2
Collier, R.J.3
-
27
-
-
0033543208
-
Anthrax protective antigen: prepore-to-pore conversion
-
Miller C.J., Elliott J.L., Collier R.J. Anthrax protective antigen: prepore-to-pore conversion. Biochemistry 1999, 38(32):10432-10441.
-
(1999)
Biochemistry
, vol.38
, Issue.32
, pp. 10432-10441
-
-
Miller, C.J.1
Elliott, J.L.2
Collier, R.J.3
-
28
-
-
0028018856
-
Anthrax protective antigen forms oligomers during intoxication of mammalian cells
-
Milne J.C., et al. Anthrax protective antigen forms oligomers during intoxication of mammalian cells. The Journal of Biological Chemistry 1994, 269(32):20607-20612.
-
(1994)
The Journal of Biological Chemistry
, vol.269
, Issue.32
, pp. 20607-20612
-
-
Milne, J.C.1
-
29
-
-
0037076364
-
The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen
-
Mogridge J., et al. The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen. Proceedings of the National Academy of Sciences of the United States of America 2002, 99(10):7045-7048.
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.10
, pp. 7045-7048
-
-
Mogridge, J.1
-
30
-
-
12544250996
-
Decreased accessibility and lack of activation of ErbB2 in JIMT-1, a herceptin-resistant, MUC4-expressing breast cancer cell line
-
Nagy P., et al. Decreased accessibility and lack of activation of ErbB2 in JIMT-1, a herceptin-resistant, MUC4-expressing breast cancer cell line. Cancer Research 2005, 65(2):473-482.
-
(2005)
Cancer Research
, vol.65
, Issue.2
, pp. 473-482
-
-
Nagy, P.1
-
31
-
-
0030835822
-
Binding proteins selected from combinatorial libraries of an alpha-helical bacterial receptor domain
-
Nord K., et al. Binding proteins selected from combinatorial libraries of an alpha-helical bacterial receptor domain. Nature Biotechnology 1997, 15(8):772-777.
-
(1997)
Nature Biotechnology
, vol.15
, Issue.8
, pp. 772-777
-
-
Nord, K.1
-
32
-
-
33646261864
-
Tumor imaging using a picomolar affinity HER2 binding affibody molecule
-
Orlova A., et al. Tumor imaging using a picomolar affinity HER2 binding affibody molecule. Cancer Research 2006, 66(8):4339-4348.
-
(2006)
Cancer Research
, vol.66
, Issue.8
, pp. 4339-4348
-
-
Orlova, A.1
-
33
-
-
34047136785
-
Immunotoxin treatment of cancer
-
Pastan I., et al. Immunotoxin treatment of cancer. Annual Review of Medicine 2007, 58:221-237.
-
(2007)
Annual Review of Medicine
, vol.58
, pp. 221-237
-
-
Pastan, I.1
-
35
-
-
35449002394
-
Mutant anthrax toxin B moiety (protective antigen) inhibits angiogenesis and tumor growth
-
Rogers M.S., et al. Mutant anthrax toxin B moiety (protective antigen) inhibits angiogenesis and tumor growth. Cancer Research 2007, 67(20):9980-9985.
-
(2007)
Cancer Research
, vol.67
, Issue.20
, pp. 9980-9985
-
-
Rogers, M.S.1
-
36
-
-
0038303163
-
Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor
-
Scobie H.M. Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor. Proceedings of the National Academy of Sciences 2003, 100(9):5170-5174.
-
(2003)
Proceedings of the National Academy of Sciences
, vol.100
, Issue.9
, pp. 5170-5174
-
-
Scobie, H.M.1
-
37
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon D.J., et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 1989, 244(4905):707-712.
-
(1989)
Science
, vol.244
, Issue.4905
, pp. 707-712
-
-
Slamon, D.J.1
-
38
-
-
12344302247
-
Characterization of a novel cell line established from a patient with herceptin-resistant breast cancer
-
Tanner M., et al. Characterization of a novel cell line established from a patient with herceptin-resistant breast cancer. Molecular Cancer Therapeutics 2004, 3(12):1585-1592.
-
(2004)
Molecular Cancer Therapeutics
, vol.3
, Issue.12
, pp. 1585-1592
-
-
Tanner, M.1
-
39
-
-
0032581369
-
Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages
-
Vitale G., et al. Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages. Biochemical and Biophysical Research Communications 1998, 248(3):706-711.
-
(1998)
Biochemical and Biophysical Research Communications
, vol.248
, Issue.3
, pp. 706-711
-
-
Vitale, G.1
-
40
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
Vogel C.L., et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology 2002, 20(3):719-726.
-
(2002)
Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
, vol.20
, Issue.3
, pp. 719-726
-
-
Vogel, C.L.1
-
41
-
-
4644247278
-
Selection and characterization of HER2/neu-binding affibody ligands
-
Wikman M., et al. Selection and characterization of HER2/neu-binding affibody ligands. Protein Engineering, Design & Selection: PEDS 2004, 17(5):455-462.
-
(2004)
Protein Engineering, Design & Selection: PEDS
, vol.17
, Issue.5
, pp. 455-462
-
-
Wikman, M.1
-
42
-
-
0023529699
-
Diphtheria toxin receptor binding domain substitution with interleukin-2: genetic construction and properties of a diphtheria toxin-related interleukin-2 fusion protein
-
Williams D.P., et al. Diphtheria toxin receptor binding domain substitution with interleukin-2: genetic construction and properties of a diphtheria toxin-related interleukin-2 fusion protein. Protein Engineering 1987, 1(6):493-498.
-
(1987)
Protein Engineering
, vol.1
, Issue.6
, pp. 493-498
-
-
Williams, D.P.1
-
43
-
-
34447291354
-
Anthrax toxin: receptor binding, internalization, pore formation, and translocation
-
Young J.A.T., Collier R.J. Anthrax toxin: receptor binding, internalization, pore formation, and translocation. Annual Review of Biochemistry 2007, 76(1):243-265.
-
(2007)
Annual Review of Biochemistry
, vol.76
, Issue.1
, pp. 243-265
-
-
Young, J.A.T.1
Collier, R.J.2
|