-
1
-
-
0032726594
-
Folding minimal sequences: The lower bound for sequence complexity of globular proteins
-
P. Romero, Z. Obradovic, and A.K. DUNKER Folding minimal sequences: The lower bound for sequence complexity of globular proteins FEBS Lett. 462 1999 363 367
-
(1999)
FEBS Lett.
, vol.462
, pp. 363-367
-
-
Romero, P.1
Obradovic, Z.2
Dunker, A.K.3
-
2
-
-
0034570889
-
Intrinsic protein disorder in complete genomes
-
A.K. Dunker, Z. Obradovic, P. Romero, E.C. Garner, and C.J. Brown Intrinsic protein disorder in complete genomes Genome Inform Ser. Workshop Genome Inform. 11 2000 161 171
-
(2000)
Genome Inform Ser. Workshop Genome Inform.
, vol.11
, pp. 161-171
-
-
Dunker, A.K.1
Obradovic, Z.2
Romero, P.3
Garner, E.C.4
Brown, C.J.5
-
3
-
-
0029662315
-
Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: Conformational disorder mediates binding diversity
-
R.W. Kriwacki, L. Hengst, L. Tennant, S.I. Reed, and P.E. Wright Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: Conformational disorder mediates binding diversity Proc. Natl. Acad. Sci. U. S. A. 93 1996 11504 11509
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 11504-11509
-
-
Kriwacki, R.W.1
Hengst, L.2
Tennant, L.3
Reed, S.I.4
Wright, P.E.5
-
4
-
-
0030980926
-
The C-terminal half of the anti-sigma factor, FlgM, becomes structured when bound to its target, s28
-
G.W. Daughdrill, M.S. Chadsey, J.E. Karlinsey, K.T. Hughes, and F.W. Dahlquist The C-terminal half of the anti-sigma factor, FlgM, becomes structured when bound to its target, s28 Nat. Struct. Biol. 4 1997 285 291
-
(1997)
Nat. Struct. Biol.
, vol.4
, pp. 285-291
-
-
Daughdrill, G.W.1
Chadsey, M.S.2
Karlinsey, J.E.3
Hughes, K.T.4
Dahlquist, F.W.5
-
5
-
-
0032570318
-
The C-terminal half of the anti-sigma factor FlgM contains a dynamic equilibrium solution structure favoring helical conformations
-
G.W. Daughdrill, L.J. Hanely, and F.W. Dahlquist The C-terminal half of the anti-sigma factor FlgM contains a dynamic equilibrium solution structure favoring helical conformations Biochemistry 37 1998 1076 1082
-
(1998)
Biochemistry
, vol.37
, pp. 1076-1082
-
-
Daughdrill, G.W.1
Hanely, L.J.2
Dahlquist, F.W.3
-
6
-
-
0344936739
-
Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: A model for activator: Coactivator interactions
-
I. Radhakrishnan, G.C. Perez-Alvarado, D. Parker, H.J. Dyson, M.R. Montminy, and P.E. Wright Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: A model for activator: Coactivator interactions Cell 91 1997 741 752
-
(1997)
Cell
, vol.91
, pp. 741-752
-
-
Radhakrishnan, I.1
Perez-Alvarado, G.C.2
Parker, D.3
Dyson, H.J.4
Montminy, M.R.5
Wright, P.E.6
-
7
-
-
0032749078
-
Intrinsically unstructured proteins: Re-assessing the protein structurefunction paradigm
-
P.E. Wright, and H.J. Dyson Intrinsically unstructured proteins: Re-assessing the protein structurefunction paradigm J. Mol. Biol. 293 1999 321 331
-
(1999)
J. Mol. Biol.
, vol.293
, pp. 321-331
-
-
Wright, P.E.1
Dyson, H.J.2
-
8
-
-
0034669882
-
Why are "natively unfolded" proteins unstructured under physiologic conditions?
-
V.N. Uversky, J.R. Gillespie, and A.L. Fink Why are "natively unfolded" proteins unstructured under physiologic conditions? Proteins 41 2000 415 427
-
(2000)
Proteins
, vol.41
, pp. 415-427
-
-
Uversky, V.N.1
Gillespie, J.R.2
Fink, A.L.3
-
10
-
-
6344277430
-
Reduced amino acid alphabet is sufficient to accurately recognize intrinsically disordered protein
-
E.A. Weathers, M.E. Paulaitis, T.B. Woolf, and J.H. Hoh Reduced amino acid alphabet is sufficient to accurately recognize intrinsically disordered protein FEBS Lett. 576 2004 348 352
-
(2004)
FEBS Lett.
, vol.576
, pp. 348-352
-
-
Weathers, E.A.1
Paulaitis, M.E.2
Woolf, T.B.3
Hoh, J.H.4
-
11
-
-
1542358787
-
Prediction and functional analysis of native disorder in proteins from the three kingdoms of life
-
J.J. Ward, J.S. Sodhi, L.J. Mcguffin, B.F. Buxton, and D.T. Jones Prediction and functional analysis of native disorder in proteins from the three kingdoms of life J. Mol. Biol. 337 2004 635 645
-
(2004)
J. Mol. Biol.
, vol.337
, pp. 635-645
-
-
Ward, J.J.1
Sodhi, J.S.2
Mcguffin, L.J.3
Buxton, B.F.4
Jones, D.T.5
-
12
-
-
24044538903
-
IUPred: Web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content
-
Z. Dosztányi, V. Csizmok, P. Tompa, and I. Simon IUPred: Web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content Bioinformatics 21 2005 3433 3434
-
(2005)
Bioinformatics
, vol.21
, pp. 3433-3434
-
-
Dosztányi, Z.1
Csizmok, V.2
Tompa, P.3
Simon, I.4
-
13
-
-
24044515001
-
FoldIndex: A simple tool to predict whether a given protein sequence is intrinsically unfolded
-
J. Prilusky, C.E. Felder, T. Zeev-Ben-Mordehei, E.H. Rydberg, O. Man, J.S. Beckmann, I. Silman, and J.L. Sussman FoldIndex: A simple tool to predict whether a given protein sequence is intrinsically unfolded Bioinformatics 21 2005 3435 3438
-
(2005)
Bioinformatics
, vol.21
, pp. 3435-3438
-
-
Prilusky, J.1
Felder, C.E.2
Zeev-Ben-Mordehei, T.3
Rydberg, E.H.4
Man, O.5
Beckmann, J.S.6
Silman, I.7
Sussman, J.L.8
-
14
-
-
33846099868
-
DisProt: The database of disordered proteins
-
M. Sickmeier, J.A. Hamilton, T. LegallL, V. Vacic, M.S. Cortese, A. Tantos, B. Szabo, P. Tompa, J. Chen, V.N. Uversky, Z. Obradovic, and A.K. Dunker DisProt: The database of disordered proteins Nucleic Acids Res. 35 2007 D786 D793
-
(2007)
Nucleic Acids Res.
, vol.35
-
-
Sickmeier, M.1
Hamilton, J.A.2
Legalll, T.3
Vacic, V.4
Cortese, M.S.5
Tantos, A.6
Szabo, B.7
Tompa, P.8
Chen, J.9
Uversky, V.N.10
Obradovic, Z.11
Dunker, A.K.12
-
15
-
-
67349162535
-
CDF it all: Consensus prediction of intrinsically disordered proteins based on various cumulative distribution functions
-
B. Xue, C.J. Oldfield, A.K. Dunker, and V.N. Uversky CDF it all: Consensus prediction of intrinsically disordered proteins based on various cumulative distribution functions FEBS Lett. 583 2009 1469 1474
-
(2009)
FEBS Lett.
, vol.583
, pp. 1469-1474
-
-
Xue, B.1
Oldfield, C.J.2
Dunker, A.K.3
Uversky, V.N.4
-
16
-
-
0036408751
-
Intrinsic disorder in cell-signaling and cancer-associated proteins
-
L.M. Iakoucheva, C.J. Brown, J.D. Lawson, Z. Obradovic, and A.K. Dunker Intrinsic disorder in cell-signaling and cancer-associated proteins J. Mol. Biol. 323 2002 573 584
-
(2002)
J. Mol. Biol.
, vol.323
, pp. 573-584
-
-
Iakoucheva, L.M.1
Brown, C.J.2
Lawson, J.D.3
Obradovic, Z.4
Dunker, A.K.5
-
17
-
-
73449123761
-
Unfoldomics of human genetic diseases: Illustrative examples of ordered and intrinsically disordered members of the human diseasome
-
U. Midic, C.J. Oldfield, A.K. Dunker, Z. Obradovic, and V.N. Uversky Unfoldomics of human genetic diseases: Illustrative examples of ordered and intrinsically disordered members of the human diseasome Protein Pept. Lett. 16 2009 1533 1547
-
(2009)
Protein Pept. Lett.
, vol.16
, pp. 1533-1547
-
-
Midic, U.1
Oldfield, C.J.2
Dunker, A.K.3
Obradovic, Z.4
Uversky, V.N.5
-
18
-
-
69149103558
-
Intrinsic disorder in proteins associated with neurodegenerative diseases
-
V.N. Uversky Intrinsic disorder in proteins associated with neurodegenerative diseases Front. Biosci. 14 2009 5188 5238
-
(2009)
Front. Biosci.
, vol.14
, pp. 5188-5238
-
-
Uversky, V.N.1
-
19
-
-
70349503591
-
Biophysics of Parkinson's disease: Structure and aggregation of asynuclein
-
V.N. Uversky, and D. Eliezer Biophysics of Parkinson's disease: Structure and aggregation of asynuclein Curr. Protein Pept. Sci. 10 2009 483 499
-
(2009)
Curr. Protein Pept. Sci.
, vol.10
, pp. 483-499
-
-
Uversky, V.N.1
Eliezer, D.2
-
21
-
-
48249097986
-
Intrinsically disordered proteins in human diseases: Introducing the D2 concept
-
V.N. Uversky, C.J. Oldfield, and A.K. Dunker Intrinsically disordered proteins in human diseases: Introducing the D2 concept Annu. Rev. Biophys. 37 2008 215 246
-
(2008)
Annu. Rev. Biophys.
, vol.37
, pp. 215-246
-
-
Uversky, V.N.1
Oldfield, C.J.2
Dunker, A.K.3
-
22
-
-
67949091224
-
Protein intrinsic disorder and influenza virulence: The 1918 H1N1 and H5N1 viruses
-
G.K. Gog, A.K. Dunker, and V.N. Uversky Protein intrinsic disorder and influenza virulence: The 1918 H1N1 and H5N1 viruses Virol. J. 6 2009 1 12
-
(2009)
Virol. J.
, vol.6
, pp. 1-12
-
-
Gog, G.K.1
Dunker, A.K.2
Uversky, V.N.3
-
23
-
-
77958103698
-
Viral disorder or disordered viruses: Do viral proteins possess unique features?
-
B. Xue, R.W. Williams, C.J. Oldfield, G.K. Goh, A.K. Dunker, and V.N. Uversky Viral disorder or disordered viruses: Do viral proteins possess unique features? Protein Pept. Lett. 17 2010 932 951
-
(2010)
Protein Pept. Lett.
, vol.17
, pp. 932-951
-
-
Xue, B.1
Williams, R.W.2
Oldfield, C.J.3
Goh, G.K.4
Dunker, A.K.5
Uversky, V.N.6
-
24
-
-
0029662315
-
Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: Conformational disorder mediates binding diversity
-
R.W. Kriwacki, L. Hengst, L. Tennant, S.I. Reed, and P.E. Wright Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: Conformational disorder mediates binding diversity Proc. Natl. Acad. Sci. U. S. A. 93 1996 11504 11509
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 11504-11509
-
-
Kriwacki, R.W.1
Hengst, L.2
Tennant, L.3
Reed, S.I.4
Wright, P.E.5
-
25
-
-
0036400715
-
Insights into the structure and dynamics of unfolded proteins from nuclear magnetic resonance
-
H.J. Dyson, and P.E. Wright Insights into the structure and dynamics of unfolded proteins from nuclear magnetic resonance Adv. Protein Chem. 62 2002 311 340
-
(2002)
Adv. Protein Chem.
, vol.62
, pp. 311-340
-
-
Dyson, H.J.1
Wright, P.E.2
-
26
-
-
0027529263
-
Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation
-
Z. Zhang, and D.L. Smith Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation Protein Sci. 2 1993 522 531
-
(1993)
Protein Sci.
, vol.2
, pp. 522-531
-
-
Zhang, Z.1
Smith, D.L.2
-
27
-
-
0032186122
-
Measurement of amide hydrogen exchange by MALDI-TOF mass spectrometry
-
J.G. Mandell, A.M. Falick, and E.A. Komives Measurement of amide hydrogen exchange by MALDI-TOF mass spectrometry Anal. Chem. 70 1998 3987 3995
-
(1998)
Anal. Chem.
, vol.70
, pp. 3987-3995
-
-
Mandell, J.G.1
Falick, A.M.2
Komives, E.A.3
-
28
-
-
0033458814
-
Unfolding dynamics of a beta-sheet protein studied by mass spectrometry
-
S.J. Eyles, T. Dresch, L.M. Gierasch, and I.A. Kaltashov Unfolding dynamics of a beta-sheet protein studied by mass spectrometry J Mass Spectrom 34 1999 1289 1295
-
(1999)
J Mass Spectrom
, vol.34
, pp. 1289-1295
-
-
Eyles, S.J.1
Dresch, T.2
Gierasch, L.M.3
Kaltashov, I.A.4
-
29
-
-
0035878163
-
Measurements of protein stability by H/D exchange and matrix-assisted laser desorption/ionization mass spectrometry using picomoles of material
-
K.D. Powell, and M.C. Fitzgerald Measurements of protein stability by H/D exchange and matrix-assisted laser desorption/ionization mass spectrometry using picomoles of material Anal. Chem. 73 2001 3300 3304
-
(2001)
Anal. Chem.
, vol.73
, pp. 3300-3304
-
-
Powell, K.D.1
Fitzgerald, M.C.2
-
30
-
-
0018801332
-
An experimental procedure for increasing the structural resolution of chemical hydrogen-exchange measurements on proteins: Application to ribonuclease S peptide
-
J.J. Rosa, and F.M. Richards An experimental procedure for increasing the structural resolution of chemical hydrogen-exchange measurements on proteins: Application to ribonuclease S peptide J. Mol. Biol. 133 1979 399 416
-
(1979)
J. Mol. Biol.
, vol.133
, pp. 399-416
-
-
Rosa, J.J.1
Richards, F.M.2
-
31
-
-
0030612609
-
Hydrogen exchange: The modern legacy of Linderstrøm-Lang
-
S. Englander, L. Mayne, Y. Bai, and T. Sosnick Hydrogen exchange: The modern legacy of Linderstrøm-Lang Protein Sci. 6 1997 1101 1109
-
(1997)
Protein Sci.
, vol.6
, pp. 1101-1109
-
-
Englander, S.1
Mayne, L.2
Bai, Y.3
Sosnick, T.4
-
32
-
-
0032428378
-
Identification of protein-protein interfaces by decreased amide proton solvent accessibility
-
J.G. Mandell, A.M. Falick, and E.A. Komives Identification of protein-protein interfaces by decreased amide proton solvent accessibility Proc. Natl. Acad. Sci. U.S.A. 95 1998 14705 14710
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 14705-14710
-
-
Mandell, J.G.1
Falick, A.M.2
Komives, E.A.3
-
33
-
-
0031890650
-
Substrate binding and conformational changes of Clostridium glutamicum diaminopimelate dehydrogenase revealed by hydrogen/deuterium exchange and electrospray mass spectrometry
-
F. Wang, G. Scapin, J.S. Blanchard, and R.H. Angeletti Substrate binding and conformational changes of Clostridium glutamicum diaminopimelate dehydrogenase revealed by hydrogen/deuterium exchange and electrospray mass spectrometry Protein Sci. 7 1998 293 299
-
(1998)
Protein Sci.
, vol.7
, pp. 293-299
-
-
Wang, F.1
Scapin, G.2
Blanchard, J.S.3
Angeletti, R.H.4
-
34
-
-
0035936704
-
Solvent accessibility of the thrombin-thrombomodulin interface
-
J.G. Mandell, A. Baerga-Ortiz, S. Akashi, K. Takio, and E.A. Komives Solvent accessibility of the thrombin-thrombomodulin interface J. Mol. Biol. 306 2001 575 589
-
(2001)
J. Mol. Biol.
, vol.306
, pp. 575-589
-
-
Mandell, J.G.1
Baerga-Ortiz, A.2
Akashi, S.3
Takio, K.4
Komives, E.A.5
-
35
-
-
0036102156
-
Epitope mapping of a monoclonal antibody against human thrombin by H/D-exchange mass spectrometry reveals selection of a diverse sequence in a highly conserved protein
-
A. Baerga-Ortiz, C.A. Hughes, J.G. Mandell, and E.A. Komives Epitope mapping of a monoclonal antibody against human thrombin by H/D-exchange mass spectrometry reveals selection of a diverse sequence in a highly conserved protein Protein Sci. 11 2002 1300 1308
-
(2002)
Protein Sci.
, vol.11
, pp. 1300-1308
-
-
Baerga-Ortiz, A.1
Hughes, C.A.2
Mandell, J.G.3
Komives, E.A.4
-
36
-
-
0027250665
-
Primary structure effects on peptide group hydrogen exchange
-
Y. Bai, J.S. Milne, L. Mayne, and S.W. Englander Primary structure effects on peptide group hydrogen exchange Proteins 17 1993 75 86
-
(1993)
Proteins
, vol.17
, pp. 75-86
-
-
Bai, Y.1
Milne, J.S.2
Mayne, L.3
Englander, S.W.4
-
37
-
-
0012206689
-
Probing protein structure and dynamics by hydrogen-exchange-mass spectrometry
-
L. Wang, and D.L. Smith Probing protein structure and dynamics by hydrogen-exchange-mass spectrometry Curr. Protoc. Protein Sci. 2002 17.6.1 17.6.18
-
(2002)
Curr. Protoc. Protein Sci.
, pp. 1761-17618
-
-
Wang, L.1
Smith, D.L.2
-
38
-
-
67650756766
-
Protein hydrogen exchange measured at single-residue resolution by electron transfer dissociation mass spectrometry
-
K.D. Rand, M. Zehl, O.N. Jensen, and T.J. Jørgensen Protein hydrogen exchange measured at single-residue resolution by electron transfer dissociation mass spectrometry Anal. Chem. 81 2009 5577 5584
-
(2009)
Anal. Chem.
, vol.81
, pp. 5577-5584
-
-
Rand, K.D.1
Zehl, M.2
Jensen, O.N.3
Jørgensen, T.J.4
-
39
-
-
82555168066
-
Spatially resolved protein hydrogen exchange measured by matrix-assisted laser desorption ionization in-source decay
-
K.D. Rand, N. Bache, M.M. Nedertoft, and T.J. Jørgensen Spatially resolved protein hydrogen exchange measured by matrix-assisted laser desorption ionization in-source decay Anal. Chem. 83 2011 8859 8862
-
(2011)
Anal. Chem.
, vol.83
, pp. 8859-8862
-
-
Rand, K.D.1
Bache, N.2
Nedertoft, M.M.3
Jørgensen, T.J.4
-
40
-
-
0346365084
-
Rare fluctuations of native proteins sampled by equilibrium hydrogen exchange
-
M. Vendruscolo, E. Paci, C.M. Dobson, and M. Karplus Rare fluctuations of native proteins sampled by equilibrium hydrogen exchange J. Am. Chem. Soc. 125 2003 15686 15687
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 15686-15687
-
-
Vendruscolo, M.1
Paci, E.2
Dobson, C.M.3
Karplus, M.4
-
41
-
-
84862908883
-
Quantitative assessment of protein structural models by comparison of H/D exchange MS data with exchange behavior accurately predicted by DXCOREX
-
T. Liu, D. Pantazatos, S. Li, Y. Hamuro, V.J. Hilser, and V.L. Woods Quantitative assessment of protein structural models by comparison of H/D exchange MS data with exchange behavior accurately predicted by DXCOREX J. Am. Soc. Mass Spectrom. 23 2012 43 56
-
(2012)
J. Am. Soc. Mass Spectrom.
, vol.23
, pp. 43-56
-
-
Liu, T.1
Pantazatos, D.2
Li, S.3
Hamuro, Y.4
Hilser, V.J.5
Woods, V.L.6
-
42
-
-
80054978046
-
Prediction of native-state hydrogen exchange from perfectly funneled energy landscapes
-
P.O. Craig, J. Lätzer, P. Weinkam, R.M. Hoffman, D.U. Ferreiro, E.A. Komives, and P.G. Wolynes Prediction of native-state hydrogen exchange from perfectly funneled energy landscapes J. Am. Chem. Soc. 133 2011 17463 17472
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 17463-17472
-
-
Craig, P.O.1
Lätzer, J.2
Weinkam, P.3
Hoffman, R.M.4
Ferreiro, D.U.5
Komives, E.A.6
Wolynes, P.G.7
-
43
-
-
1642514905
-
Rapid refinement of crystallographic protein construct definition employing enhanced hydrogen/deuterium exchange MS
-
D. Pantazatos, J.S. Kim, H.E. Klock, R.C. Stevens, I.A. Wilson, S.A. Lesley, and V.L. Woods Rapid refinement of crystallographic protein construct definition employing enhanced hydrogen/deuterium exchange MS Proc. Natl. Acad. Sci. U. S. A. 101 2004 751
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 751
-
-
Pantazatos, D.1
Kim, J.S.2
Klock, H.E.3
Stevens, R.C.4
Wilson, I.A.5
Lesley, S.A.6
Woods, V.L.7
-
44
-
-
68149164336
-
Construct optimization for protein NMR structure analysis using amide hydrogen/deuterium exchange mass spectrometry
-
S. Sharma, H. Zheng, Y.J. Huang, A. Ertekin, Y. Hamuro, P. Rossi, R. Tejero, T.B. Acton, R. Xiao, M. Jiang, L. Zhao, L.C. Ma, G.V. Swapna, J.M. Aramini, and G.T. Montelione Construct optimization for protein NMR structure analysis using amide hydrogen/deuterium exchange mass spectrometry Proteins 76 2009 882 894
-
(2009)
Proteins
, vol.76
, pp. 882-894
-
-
Sharma, S.1
Zheng, H.2
Huang, Y.J.3
Ertekin, A.4
Hamuro, Y.5
Rossi, P.6
Tejero, R.7
Acton, T.B.8
Xiao, R.9
Jiang, M.10
Zhao, L.11
Ma, L.C.12
Swapna, G.V.13
Aramini, J.M.14
Montelione, G.T.15
-
45
-
-
84860857091
-
Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered n-terminal region
-
A. Ertekin, J.M. Aramini, P. Rossi, P.G. Leonard, H. Janjua, R. Xiao, M. Maglaqui, H.W. Lee, J.H. Prestegard, and G.T. Montelione Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered n-terminal region J. Biol. Chem. 287 2012 16541 16549
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 16541-16549
-
-
Ertekin, A.1
Aramini, J.M.2
Rossi, P.3
Leonard, P.G.4
Janjua, H.5
Xiao, R.6
Maglaqui, M.7
Lee, H.W.8
Prestegard, J.H.9
Montelione, G.T.10
-
46
-
-
84866050024
-
Protein disorder and short conserved motifs in disordered regions are enriched near the cytoplasmic side of single-pass transmembrane proteins
-
I. Stavropoulos, N. Khaldi, N.E. Davey, K. O'Brien, F. Martin, and D.C. Shields Protein disorder and short conserved motifs in disordered regions are enriched near the cytoplasmic side of single-pass transmembrane proteins PLoS One 7 e44389 2012 1 8
-
(2012)
PLoS One
, vol.7
, Issue.E44389
, pp. 1-8
-
-
Stavropoulos, I.1
Khaldi, N.2
Davey, N.E.3
O'brien, K.4
Martin, F.5
Shields, D.C.6
-
47
-
-
47049086608
-
Structural and functional consequences of tyrosine phosphorylation in the LRP1 cytoplasmic domain
-
G.N. Betts, P. Van Der Geer, and E.A. Komives Structural and functional consequences of tyrosine phosphorylation in the LRP1 cytoplasmic domain J. Biol. Chem. 283 2008 15656 15664
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 15656-15664
-
-
Betts, G.N.1
Van Der Geer, P.2
Komives, E.A.3
-
48
-
-
84855740330
-
Advances and challenges in analytical characterization of biotechnology products: Mass spectrometry-based approaches to study properties and behavior of protein therapeutics
-
I.A. Kaltashov, C.E. Bobst, R.R. Abzalimov, G. Wang, B. Baykal, and S. Wang Advances and challenges in analytical characterization of biotechnology products: Mass spectrometry-based approaches to study properties and behavior of protein therapeutics Biotechnol Adv 30 2011 210 222
-
(2011)
Biotechnol Adv
, vol.30
, pp. 210-222
-
-
Kaltashov, I.A.1
Bobst, C.E.2
Abzalimov, R.R.3
Wang, G.4
Baykal, B.5
Wang, S.6
-
49
-
-
53049096591
-
Phenotype, diagnosis, and treatment of Gaucher's disease
-
GA G. Phenotype, diagnosis, and treatment of Gaucher's disease Lancet 372 2008 1263 1271
-
(2008)
Lancet
, vol.372
, pp. 1263-1271
-
-
Ga, G.1
-
50
-
-
78649674865
-
Impact of oxidation on protein therapeutics: Conformational dynamics of intact and oxidized acid-β-glucocerebrosidase at near-physiological pH
-
C.E. Bobst, J.J. Thomas, P.A. Salinas, P. Savickas, and I.A. Kaltashov Impact of oxidation on protein therapeutics: Conformational dynamics of intact and oxidized acid-β-glucocerebrosidase at near-physiological pH Protein Sci. 19 2010 2366 2378
-
(2010)
Protein Sci.
, vol.19
, pp. 2366-2378
-
-
Bobst, C.E.1
Thomas, J.J.2
Salinas, P.A.3
Savickas, P.4
Kaltashov, I.A.5
-
51
-
-
79954547968
-
The utility of hydrogen/deuterium exchange mass spectrometry in biopharmaceutical comparability studies
-
D. Houde, S.A. Berkowitz, and J.R. Engen The utility of hydrogen/deuterium exchange mass spectrometry in biopharmaceutical comparability studies J. Pharm. Sci. 100 2011 2071 2086
-
(2011)
J. Pharm. Sci.
, vol.100
, pp. 2071-2086
-
-
Houde, D.1
Berkowitz, S.A.2
Engen, J.R.3
-
52
-
-
76749099328
-
Conformation and dynamics of biopharmaceuticals: Transition of mass spectrometry-based tools from academe to industry
-
I.A. Kaltashov, C.E. Bobst, R.R. Abzalimov, S.A. Berkowitz, and D. Houde Conformation and dynamics of biopharmaceuticals: Transition of mass spectrometry-based tools from academe to industry J. Am. Soc. Mass Spectrom. 21 2010 323 337
-
(2010)
J. Am. Soc. Mass Spectrom.
, vol.21
, pp. 323-337
-
-
Kaltashov, I.A.1
Bobst, C.E.2
Abzalimov, R.R.3
Berkowitz, S.A.4
Houde, D.5
-
53
-
-
0028971289
-
Rel/NF-kappa B/I kappa B family: Intimate tales of association and dissociation
-
I.M. Verma, J.K. Stevenson, E.M. Schwarz, D. Van Antwerp, and S. Miyamoto Rel/NF-kappa B/I kappa B family: Intimate tales of association and dissociation Genes Dev. 9 1995 2723 2735
-
(1995)
Genes Dev.
, vol.9
, pp. 2723-2735
-
-
Verma, I.M.1
Stevenson, J.K.2
Schwarz, E.M.3
Van Antwerp, D.4
Miyamoto, S.5
-
54
-
-
3042628330
-
Biophysical characterization of the free IkappaBalpha ankyrin repeat domain in solution
-
C.H. Croy, S. Bergqvist, T. Huxford, G. Ghosh, and E.A. Komives Biophysical characterization of the free IkappaBalpha ankyrin repeat domain in solution Protein Sci. 13 2004 1767 1777
-
(2004)
Protein Sci.
, vol.13
, pp. 1767-1777
-
-
Croy, C.H.1
Bergqvist, S.2
Huxford, T.3
Ghosh, G.4
Komives, E.A.5
-
55
-
-
33750329946
-
Solvent accessibility of protein surfaces by amide H/2H exchange MALDI-TOF mass spectrometry
-
S.M.E. Truhlar, C.H. Croy, J.W. Torpey, J.R. Koeppe, and E.A. Komives Solvent accessibility of protein surfaces by amide H/2H exchange MALDI-TOF mass spectrometry J. Am. Soc. Mass Spectrom. 17 2006 1490 1497
-
(2006)
J. Am. Soc. Mass Spectrom.
, vol.17
, pp. 1490-1497
-
-
Truhlar, S.M.E.1
Croy, C.H.2
Torpey, J.W.3
Koeppe, J.R.4
Komives, E.A.5
-
56
-
-
0030199899
-
Mass spectrometric determination of isotopic exchange rates of amide hydrogens located on the surfaces of proteins
-
K. Dharmasiri, and D.L. Smith Mass spectrometric determination of isotopic exchange rates of amide hydrogens located on the surfaces of proteins Anal. Chem. 68 1996 2340 2344
-
(1996)
Anal. Chem.
, vol.68
, pp. 2340-2344
-
-
Dharmasiri, K.1
Smith, D.L.2
-
57
-
-
34447628760
-
Regions of IkappaBalpha that are critical for its inhibition of NF-kappaB.DNA interaction fold upon binding to NF-kappaB
-
S.M. Truhlar, J.W. Torpey, and E.A. Komives Regions of IkappaBalpha that are critical for its inhibition of NF-kappaB.DNA interaction fold upon binding to NF-kappaB Proc. Natl. Acad. Sci. U. S. A. 103 2006 18951 18956
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 18951-18956
-
-
Truhlar, S.M.1
Torpey, J.W.2
Komives, E.A.3
-
58
-
-
0037203771
-
Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators
-
S.J. Demarest, M. Martinez-Yamout, J. Chung, H. Chen, W. Xu, H.J. Dyson, R.M. Evans, and P.E. Wright Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators Nature 415 2002 549 553
-
(2002)
Nature
, vol.415
, pp. 549-553
-
-
Demarest, S.J.1
Martinez-Yamout, M.2
Chung, J.3
Chen, H.4
Xu, W.5
Dyson, H.J.6
Evans, R.M.7
Wright, P.E.8
-
59
-
-
80053581731
-
Mapping unstructured regions and synergistic folding in intrinsically disordered proteins with amide H/D exchange mass spectrometry
-
T.R. Keppel, B.A. Howard, and D.D. Weis Mapping unstructured regions and synergistic folding in intrinsically disordered proteins with amide H/D exchange mass spectrometry Biochemistry 50 2011 8722 8732
-
(2011)
Biochemistry
, vol.50
, pp. 8722-8732
-
-
Keppel, T.R.1
Howard, B.A.2
Weis, D.D.3
-
60
-
-
77955442470
-
Conformational selection in the molten globule state of the nuclear coactivator binding domain of CBP
-
M. Kjaergaard, K. Teilum, and F.M. Poulsen Conformational selection in the molten globule state of the nuclear coactivator binding domain of CBP Proc. Natl. Acad. Sci. U. S. A. 107 2010 12535 12540
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 12535-12540
-
-
Kjaergaard, M.1
Teilum, K.2
Poulsen, F.M.3
-
61
-
-
33745428137
-
Ligation-state hydrogen exchange: Coupled binding and folding equilibria in ribonuclease P protein
-
C.H. Henkels, and T.G. Oas Ligation-state hydrogen exchange: Coupled binding and folding equilibria in ribonuclease P protein J. Am. Chem. Soc. 128 2006 7772 7781
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 7772-7781
-
-
Henkels, C.H.1
Oas, T.G.2
-
62
-
-
15544363358
-
Unfolding, aggregation, and seeded amyloid formation of lysine-58-cleaved beta 2-microglobulin
-
N.H. Heegaard, T.J. Jørgensen, N. Rozlosnik, D.B. Corlin, J.S. Pedersen, A.G. Tempesta, P. Roepstorff, R. Bauer, and M.H. Nissen Unfolding, aggregation, and seeded amyloid formation of lysine-58-cleaved beta 2-microglobulin Biochemistry 44 2005 4397 4407
-
(2005)
Biochemistry
, vol.44
, pp. 4397-4407
-
-
Heegaard, N.H.1
Jørgensen, T.J.2
Rozlosnik, N.3
Corlin, D.B.4
Pedersen, J.S.5
Tempesta, A.G.6
Roepstorff, P.7
Bauer, R.8
Nissen, M.H.9
-
63
-
-
0021752457
-
Purification and structural studies of a major scrapie prion protein
-
S.B. Prusiner, D.F. Groth, D.C. Bolton, S.B. Kent, and L.E. Hood Purification and structural studies of a major scrapie prion protein Cell 38 1984 127 134
-
(1984)
Cell
, vol.38
, pp. 127-134
-
-
Prusiner, S.B.1
Groth, D.F.2
Bolton, D.C.3
Kent, S.B.4
Hood, L.E.5
-
64
-
-
70349858126
-
Ultrastructures and strain comparison of under-glycosylated scrapie prion fibrils
-
V.L. Sim, and B. Caughey Ultrastructures and strain comparison of under-glycosylated scrapie prion fibrils Neurobiol Aging 30 2009 2031 2042
-
(2009)
Neurobiol Aging
, vol.30
, pp. 2031-2042
-
-
Sim, V.L.1
Caughey, B.2
-
65
-
-
77957756752
-
Probing the conformation of a prion protein fibril with hydrogen dxchange
-
S.M. Damo, A.H. Phillips, A.L. Young, S. Li, V.L. Woods, and D.E. Wemmer Probing the conformation of a prion protein fibril with hydrogen dxchange J. Biol. Chem. 285 2010 32303 32311
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 32303-32311
-
-
Damo, S.M.1
Phillips, A.H.2
Young, A.L.3
Li, S.4
Woods, V.L.5
Wemmer, D.E.6
-
66
-
-
79953785159
-
Structural organization of brain-derived mammalian prions examined by hydrogen-deuterium exchange
-
V. Smirnovas, G.S. Baron, D.K. Offerdahl, G.J. Raymond, B. Caughey, and W.K. Surewicz Structural organization of brain-derived mammalian prions examined by hydrogen-deuterium exchange Nat. Struct. Mol. Biol. 18 2011 504 506
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 504-506
-
-
Smirnovas, V.1
Baron, G.S.2
Offerdahl, D.K.3
Raymond, G.J.4
Caughey, B.5
Surewicz, W.K.6
-
67
-
-
33846811599
-
Beta-Sheet core of human prion protein amyloid fibrils as determined by hydrogen/deuterium exchange
-
X. Lu, P.L. Wintrode, and W.K. Surewicz Beta-Sheet core of human prion protein amyloid fibrils as determined by hydrogen/deuterium exchange Proc. Natl. Acad. Sci. U. S. A. 104 2007 1510 1515
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 1510-1515
-
-
Lu, X.1
Wintrode, P.L.2
Surewicz, W.K.3
-
68
-
-
7444240183
-
Probing the instabilities in the dynamics of helical fragments from mouse PrPC
-
R.I. Dima, and D. Thirumalai Probing the instabilities in the dynamics of helical fragments from mouse PrPC Proc. Natl. Acad. Sci. U. S. A. 101 2004 15335 15340
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 15335-15340
-
-
Dima, R.I.1
Thirumalai, D.2
-
69
-
-
77955682352
-
Structure and intermolecular dynamics of aggregates populated during amyloid fibril formation studied by hydrogen/deuterium exchange
-
N. Carulla, M. Zhou, E. Giralt, C.V. Robinson, and C.M. Dobson Structure and intermolecular dynamics of aggregates populated during amyloid fibril formation studied by hydrogen/deuterium exchange Acc. Chem. Res. 43 2010 1072 1079
-
(2010)
Acc. Chem. Res.
, vol.43
, pp. 1072-1079
-
-
Carulla, N.1
Zhou, M.2
Giralt, E.3
Robinson, C.V.4
Dobson, C.M.5
-
70
-
-
51549121010
-
High-speed and high-resolution UPLC separation at zero degrees Celsius
-
T.E. Wales, K.E. Fadgen, G.C. Gerhardt, and J.R. Engen High-speed and high-resolution UPLC separation at zero degrees Celsius Anal. Chem. 80 2008 6815 6820
-
(2008)
Anal. Chem.
, vol.80
, pp. 6815-6820
-
-
Wales, T.E.1
Fadgen, K.E.2
Gerhardt, G.C.3
Engen, J.R.4
-
71
-
-
67650756766
-
Protein hydrogen exchange measured at single-residue resolution by electron transfer dissociation mass spectrometry
-
K.D. Rand, M. Zehl, O.N. Jensen, and T.J. Jørgensen Protein hydrogen exchange measured at single-residue resolution by electron transfer dissociation mass spectrometry Anal. Chem. 81 2009 5577 5584
-
(2009)
Anal. Chem.
, vol.81
, pp. 5577-5584
-
-
Rand, K.D.1
Zehl, M.2
Jensen, O.N.3
Jørgensen, T.J.4
-
72
-
-
80855156910
-
ETD in a traveling wave ion guide at tuned Z-spray ion source conditions allows for site-specific hydrogen/deuterium exchange measurements
-
K.D. Rand, S.D. Pringle, M. Morris, J.R. Engen, and J.M. Brown ETD in a traveling wave ion guide at tuned Z-spray ion source conditions allows for site-specific hydrogen/deuterium exchange measurements J. Am. Soc. Mass Spectrom. 22 2011 1784 1793
-
(2011)
J. Am. Soc. Mass Spectrom.
, vol.22
, pp. 1784-1793
-
-
Rand, K.D.1
Pringle, S.D.2
Morris, M.3
Engen, J.R.4
Brown, J.M.5
-
73
-
-
84861181306
-
Spatially resolved protein hydrogen exchange measured by subzero-cooled chip-based nanoelectrospray ionization tandem mass spectrometry
-
S. Amon, M.B. Trelle, O.N. Jensen, and T.J. Jørgensen Spatially resolved protein hydrogen exchange measured by subzero-cooled chip-based nanoelectrospray ionization tandem mass spectrometry Anal. Chem. 84 2012 4467 4473
-
(2012)
Anal. Chem.
, vol.84
, pp. 4467-4473
-
-
Amon, S.1
Trelle, M.B.2
Jensen, O.N.3
Jørgensen, T.J.4
|