Clinical characteristics and survival data of melanoma patients with nevus cell aggregates within sentinel lymph nodes

American Journal of Clinical Pathology

Volumn 139, Issue 5, 2013, Pages 566-573

  Gambichler, Thilo ^a   Scholl, Lisa ^a   Stücker, Markus ^a   Bechara, Falk G ^a   Hoffmann, Klaus ^a   Altmeyer, Peter ^a   Othlinghaus, Nick ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Malignant melanoma; Nevus cell aggregates; Nodal nevus; Sentinel lymph node

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER SURVIVAL; CELL AGGREGATION; CLINICAL FEATURE; DISEASE FREE SURVIVAL; FEMALE; HISTOPATHOLOGY; HUMAN; MAJOR CLINICAL STUDY; MALE; MELANOMA; NEVUS CELL; OVERALL SURVIVAL; PRIORITY JOURNAL; SENTINEL LYMPH NODE; SENTINEL LYMPH NODE BIOPSY; SURVIVAL PREDICTION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; DIAGNOSIS, DIFFERENTIAL; DISEASE-FREE SURVIVAL; FEMALE; GERMANY; HUMANS; KAPLAN-MEIER ESTIMATE; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MELANOMA; MIDDLE AGED; NEOPLASMS, MULTIPLE PRIMARY; NEVUS; REPRODUCIBILITY OF RESULTS; SENTINEL LYMPH NODE BIOPSY; SKIN NEOPLASMS; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84878080508     PISSN: 00029173     EISSN: 19437722     Source Type: Journal    
DOI: 10.1309/AJCPG83CMAVFBWLC     Document Type: Article

References (32)

1. Carson KF, Wen DR, Li PX, et al. Nodal nevi and cutaneous melanomas. Am J Surg Pathol. 1996;20:834-840.
2. Ridolfi RL, Rosen PP, Thaler H. Nevus cell aggregates associated with lymph nodes: estimated frequency and clinical significance. Cancer. 1977;39:164-171.
3. Patterson JW. Nevus cell aggregates in lymph nodes. Am J Clin Pathol. 2004;121:13-15.
4. Bautista NC, Cohen S, Anders KH. Benign melanocytic nevus cells in axillary lymph nodes: a prospective incidence and immunohistochemical study with literature review. Am J Clin Pathol. 1994;102:102-108.
5. Fontaine D, Parkhill W, Greer W, et al. Nevus cells in lymph nodes: an association with congenital cutaneous nevi. Am J Dermatopathol. 2002;24:1-5.
6. Holt JB, Sangueza OP, Levine EA, et al. Nodal melanocytic nevi in sentinel lymph nodes: correlation with melanomaassociated cutaneous nevi. Am J Clin Pathol. 2004;121:58-63.
7. Witte ME, Gerrits EG, Klaase JM, et al. Distinguishing nodal naevus from melanoma metastases in the sentinel node in patients with melanoma [in Dutch]. Ned Tijdschr Geneeskd. 2006;150:1072-1076.
8. Andreola S, Clemente C. Nevus cells in axillary lymph nodes from radical mastectomy specimens. Pathol Res Pract. 1985;179:616-618.
9. Biddle DA, Evans HL, Kemp BL, et al. Intraparenchymal nevus cell aggregates in lymph nodes: a possible diagnostic pitfall with malignant melanoma and carcinoma. Am J Surg Pathol. 2003;27:673-681.
10. Parker JR, Ro JY, Ordóñez NG. Benign nevus cell aggregates in the thymus: a case report. Mod Pathol. 1999;12:329-332.
11. Jensen JL, Correll RW. Nevus cell aggregates in submandibular lymph nodes. Oral Surg Oral Med Oral Pathol. 1980;50:552-556.
12. Urso C. Nodal melanocytic nevus with balloon-cell change (nodal balloon-cell nevus). J Cutan Pathol. 2008;35:672-676.
13. Scheller K, Scheller C, Becker S, et al. Cellular blue nevus (CBN) lymph node metastases of the neck with no primary skin lesion: a case report and review of literature. J Craniomaxillofac Surg. 2010;38:601-604.
14. Dohse L, Ferringer T. Nodal blue nevus: a pitfall in lymph node biopsies. J Cutan Pathol. 2010;37:102-104.
15. Busam KJ, Murali R, Pulitzer M, et al. Atypical spitzoid melanocytic tumors with positive sentinel lymph nodes in children and teenagers, and comparison with histologically unambiguous and lethal melanomas. Am J Surg Pathol. 2009;33:1386-1395.
16. Mihic-Probst D, Saremaslani P, Komminoth P, et al. Immunostaining for the tumour suppressor gene p16 product is a useful marker to differentiate melanoma metastasis from lymph-node nevus. Virchows Arch. 2003;443:745-751.
17. Lohmann CM, Iversen K, Jungbluth AA, et al. Expression of melanocyte differentiation antigens and ki-67 in nodal nevi and comparison of ki-67 expression with metastatic melanoma. Am J Surg Pathol. 2002;26:1351-1357.
18. Dalton SR, Gerami P, Kolaitis NA, et al. Use of fluorescence in situ hybridization (FISH) to distinguish intranodal nevus from metastatic melanoma. Am J Surg Pathol. 2010;34:231-237.
19. Taube JM, Begum S, Shi C, et al. Benign nodal nevi frequently harbor the activating V600E BRAF mutation. Am J Surg Pathol. 2009;33:568-571.
20. Mentrikoski MJ, Ma L, Pryor JG, et al. Diagnostic utility of IMP3 in segregating metastatic melanoma from benign nevi in lymph nodes. Mod Pathol. 2009;22:1582-1587.
21. Pulitzer MP, Gerami P, Busam K. Solar elastotic material in dermal lymphatics and lymph nodes. Am J Surg Pathol. 2010;34:1492-1497.
22. McCalmont TH, Bastian BC. An unconventional deep penetrating melanocytic nevus with microscopic involvement of regional lymph nodes. J Cutan Pathol. 2012;39:25-28.
23. Wong SL, Balch CM, Hurley P, et al. Sentinel lymph node biopsy for melanoma: American Society of Clinical Oncology and Society of Surgical Oncology joint clinical practice guideline. J Clin Oncol. 2012;8:e65-e66.
24. Scolyer RA, Murali R, McCarthy SW, et al. Histologically ambiguous ("borderline") primary cutaneous melanocytic tumors: approaches to patient management including the roles of molecular testing and sentinel lymph node biopsy. Arch Pathol Lab Med. 2010;134:1770-1777.
25. Scolyer RA, Murali R, McCarthy SW, et al. Pathologic examination of sentinel lymph nodes from melanoma patients. Semin Diagn Pathol. 2008;25:100-111.
26. Taylor RC, Patel A, Panageas KS, et al. Tumor-infiltrating lymphocytes predict sentinel lymph node positivity in patients with cutaneous melanoma. J Clin Oncol. 2007;25:869-875.
27. Kruper LL, Spitz FR, Czerniecki BJ, et al. Predicting sentinel node status in AJCC stage I/II primary cutaneous melanoma. Cancer. 2006;107:2436-2445.
28. Callender GG, Egger ME, Burton AL, et al. Prognostic implications of anatomic location of primary cutaneous melanoma of 1 mm or thicker. Am J Surg. 2011;202:659-664.
29. Ito T, Moroi Y, Oba J, et al. The prognostic value of a reverse transcriptase-PCR assay of sentinel lymph node biopsy for patients with cutaneous melanoma: a single-center analysis in Japan. Melanoma Res. 2012;22:38-44.
30. Homsi J, Kashani-Sabet M, Messina JL, et al. Cutaneous melanoma: prognostic factors. Cancer Control. 2005;12:223-229.
31. Bowles TL, Xing Y, Hu CY, et al. Conditional survival estimates improve over 5 years for melanoma survivors with node-positive disease. Ann Surg Oncol. 2010;17:2015-2023.
32. Balch CM, Gershenwald JE, Soong SJ, et al. Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol. 2009;27:6199-6206.