-
1
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans
-
DOI 10.1038/35888
-
Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., and Mello, C. C. (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans Nature 391, 806-811 (Pubitemid 28099681)
-
(1998)
Nature
, vol.391
, Issue.6669
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
2
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
DOI 10.1038/35078107
-
Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., and Tuschl, T. (2001) Duplexes of 21-nucleotide RNAs mediate RNAinterference in cultured mammalian cells Nature 411, 494-498 (Pubitemid 32494397)
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
3
-
-
84863932966
-
Molecular mechanisms of RNA-triggered gene silencing machineries
-
Li, Z. and Rana, T. M. (2012) Molecular mechanisms of RNA-triggered gene silencing machineries Acc. Chem. Res. 45, 1122-1131
-
(2012)
Acc. Chem. Res.
, vol.45
, pp. 1122-1131
-
-
Li, Z.1
Rana, T.M.2
-
4
-
-
77957820261
-
RNAi and small interfering RNAs in human disease therapeutic applications
-
Lares, M. R., Rossi, J. J., and Ouellet, D. L. (2010) RNAi and small interfering RNAs in human disease therapeutic applications Trends Biotechnol. 28, 570-579
-
(2010)
Trends Biotechnol.
, vol.28
, pp. 570-579
-
-
Lares, M.R.1
Rossi, J.J.2
Ouellet, D.L.3
-
5
-
-
33746228119
-
Knocking down Disease with siRNAs
-
DOI 10.1016/j.cell.2006.07.007, PII S0092867406009007
-
Dykxhoorn, D. M. and Lieberman, J. (2006) Knocking down disease with siRNAs Cell 126, 231-235 (Pubitemid 44092975)
-
(2006)
Cell
, vol.126
, Issue.2
, pp. 231-235
-
-
Dykxhoorn, D.M.1
Lieberman, J.2
-
6
-
-
9144247189
-
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
-
DOI 10.1038/nature03121
-
Soutschek, J., Akinc, A., Bramlage, B., Charisse, K., Constien, R., Donoghue, M., Elbashir, S., Geick, A., Hadwiger, P., Harborth, J., John, M., Kesavan, V., Lavine, G., Pandey, R. K., Racie, T., Rajeev, K. G., Röhl, I., Toudjarska, I., Wang, G., Wuschko1, S., Bumcrot, D., Koteliansky, V., Limmer, S., Manoharan, M., and Vornlocher, H.-P. (2004) Therapeutic silencing of an endogenous gene by systematic administration of modified siRNAs Nature 432, 173-178 (Pubitemid 39545841)
-
(2004)
Nature
, vol.432
, Issue.7014
, pp. 173-178
-
-
Soutschek, J.1
Akinc, A.2
Bramlage, B.3
Charisse, K.4
Constien, R.5
Donoghue, M.6
Elbashir, S.7
Gelck, A.8
Hadwiger, P.9
Harborth, J.10
John, M.11
Kesavan, V.12
Lavine, G.13
Pandey, R.K.14
Racie, T.15
Rajeev, K.S.16
Rohl, I.17
Toudjarska, I.18
Wang, G.19
Wuschko, S.20
Bumcrot, D.21
Kotellansky, V.22
Limmer, S.23
Manoharan, M.24
Vornlocher, H.-P.25
more..
-
7
-
-
84863903929
-
Nucleic acid delivery: The missing pieces of the puzzle?
-
Nguyen, J. and Szoka, F. C. (2012) Nucleic acid delivery: The missing pieces of the puzzle? Acc. Chem. Res. 45, 1153-1162
-
(2012)
Acc. Chem. Res.
, vol.45
, pp. 1153-1162
-
-
Nguyen, J.1
Szoka, F.C.2
-
8
-
-
59349116903
-
Knocking down barriers: Advances in siRNA delivery
-
Whitehead, K. A., Langer, R., and Anderson, D. G. (2009) Knocking down barriers: advances in siRNA delivery Nat. Drug Discovery Rev. 8, 129-138
-
(2009)
Nat. Drug Discovery Rev.
, vol.8
, pp. 129-138
-
-
Whitehead, K.A.1
Langer, R.2
Anderson, D.G.3
-
9
-
-
80053595546
-
Phenylpyrrolocytosine as an unobtrusive base modification for monitoring activity and cellular trafficking of siRNA
-
Wahba, A. S., Azizi, F., Deleavey, G. F., Brown, C., Robert, F., Carrier, M., Kalota, A., Gewirtz, A. M., Pelletier, J., Hudson, R. H. E., and Damha, M. J. (2011) Phenylpyrrolocytosine as an unobtrusive base modification for monitoring activity and cellular trafficking of siRNA Chem. Biol. 6, 912-919
-
(2011)
Chem. Biol.
, vol.6
, pp. 912-919
-
-
Wahba, A.S.1
Azizi, F.2
Deleavey, G.F.3
Brown, C.4
Robert, F.5
Carrier, M.6
Kalota, A.7
Gewirtz, A.M.8
Pelletier, J.9
Hudson, R.H.E.10
Damha, M.J.11
-
10
-
-
0344824383
-
Visualizing the distribution and transport of mRNAs in living cells
-
DOI 10.1073/pnas.2233244100
-
Bratu, D. P., Cha, B.-J., Mhlanga, M. M., Kramer, F. R., and Tyagi, S. (2003) Visualizing the distribution and transport of mRNAs in living cells Proc. Natl. Acad. Sci. U.S.A. 100, 13308-13313 (Pubitemid 37444738)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.23
, pp. 13308-13313
-
-
Bratu, D.P.1
Cha, B.-J.2
Mhlanga, M.M.3
Kramer, F.R.4
Tyagi, S.5
-
11
-
-
70149090352
-
Imaging of mRNA in living cells using nucleic-acid templated reduction of azidorhodamine probes
-
Pianowski, Z., Gorska, K., Oswald, L., Merten, C. A., and Winssinger, N. (2009) Imaging of mRNA in living cells using nucleic-acid templated reduction of azidorhodamine probes J. Am. Chem. Soc. 131, 6492-6497
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 6492-6497
-
-
Pianowski, Z.1
Gorska, K.2
Oswald, L.3
Merten, C.A.4
Winssinger, N.5
-
12
-
-
0032562720
-
Visualization of single RNA transcripts in situ
-
DOI 10.1126/science.280.5363.585
-
Femino, A. M., Fay, F. S., Fogarty, K., and Singer, R. H. (1998) Visualization of single RNA transcripts in situ Science 280, 585-590 (Pubitemid 28227761)
-
(1998)
Science
, vol.280
, Issue.5363
, pp. 585-590
-
-
Femino, A.M.1
Fay, F.S.2
Fogarty, K.3
Singer, R.H.4
-
13
-
-
33748253098
-
In situ analysis of single-stranded and duplex siRNA integrity in living cells
-
DOI 10.1021/bi060351b
-
Raimdonck, K., Remaut, K., Lucas, B., Sanders, N. N., Demeester, J., and De Smedt, S. C. (2006) In situ analysis of single-stranded and duplex siRNA integrity in living cells Biochemistry 45, 10614-10623 (Pubitemid 44320476)
-
(2006)
Biochemistry
, vol.45
, Issue.35
, pp. 10614-10623
-
-
Raemdonck, K.1
Remaut, K.2
Lucas, B.3
Sanders, N.N.4
Demeester, J.5
De Smedt, S.C.6
-
14
-
-
35548965556
-
Surveillance of siRNA integrity by FRET imaging
-
Jarve, A., Muller, J., Kim, I. H., Rohr, K., MacLean, C., Fricker, G., Massing, U., Eberle, F., Dalpke, A., Fischer, R., Trendelenburg, M. F., and Helm, M. (2007) Surveillance of siRNA integrity by FRET imaging Nucleic Acids Res. 35, e124
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 124
-
-
Jarve, A.1
Muller, J.2
Kim, I.H.3
Rohr, K.4
MacLean, C.5
Fricker, G.6
Massing, U.7
Eberle, F.8
Dalpke, A.9
Fischer, R.10
Trendelenburg, M.F.11
Helm, M.12
-
15
-
-
79959233482
-
ET-based probing to gain direct information on siRNA sustainability in live cells: Asymmetric degradation of siRNA strands
-
Shin, S., Kwon, H.-M., Yoon, K.-S., Kim, D.-E., and Hah, S. S. (2011) ET-based probing to gain direct information on siRNA sustainability in live cells: Asymmetric degradation of siRNA strands Mol. Biosyst. 7, 2210-2113
-
(2011)
Mol. Biosyst.
, vol.7
, pp. 2210-2113
-
-
Shin, S.1
Kwon, H.-M.2
Yoon, K.-S.3
Kim, D.-E.4
Hah, S.S.5
-
16
-
-
79951806917
-
Fluorescence imaging of influenza H1N1 mRNA in living infected cells using single-chromophore FIT-PNA
-
Kummer, S., Knoll, A., Socher, E., Bethge, L., Herrmann, A., and Seitz, O. (2011) Fluorescence imaging of influenza H1N1 mRNA in living infected cells using single-chromophore FIT-PNA Angew. Chem., Int. Ed. 50, 1931-1934
-
(2011)
Angew. Chem., Int. Ed.
, vol.50
, pp. 1931-1934
-
-
Kummer, S.1
Knoll, A.2
Socher, E.3
Bethge, L.4
Herrmann, A.5
Seitz, O.6
-
17
-
-
84867508726
-
PNA FIT-Probes for the dual color imaging of two viral mRNA targets in influenza H1N1 infected live cells
-
Kummer, S., Knoll, A., Socher, E., Bethge, L., Herrmann, A., and Seitz, O. (2012) PNA FIT-Probes for the dual color imaging of two viral mRNA targets in influenza H1N1 infected live cells Bioconjugate Chem. 23, 2051-2060
-
(2012)
Bioconjugate Chem.
, vol.23
, pp. 2051-2060
-
-
Kummer, S.1
Knoll, A.2
Socher, E.3
Bethge, L.4
Herrmann, A.5
Seitz, O.6
-
18
-
-
80054009960
-
ECHO probes: A concept of fluorescence control for practical nucleic acid sensing
-
Okamoto, A. (2011) ECHO probes: a concept of fluorescence control for practical nucleic acid sensing Chem. Soc. Rev. 40, 5815-5828
-
(2011)
Chem. Soc. Rev.
, vol.40
, pp. 5815-5828
-
-
Okamoto, A.1
-
19
-
-
34547923688
-
Cyanine dye conjugates as probes for live cell imaging
-
DOI 10.1016/j.bmcl.2007.06.097, PII S0960894X07007925
-
Carreon, J. R., Stewart, K. M., Mahon, K. P., Jr., Shin, S., and Kelley, S. O. (2007) Cyanine dye conjugates as probes for live cell imaging Bioorg. Med. Chem. Lett. 17, 5182-5185 (Pubitemid 47259652)
-
(2007)
Bioorganic and Medicinal Chemistry Letters
, vol.17
, Issue.18
, pp. 5182-5185
-
-
Carreon, J.R.1
Stewart, K.M.2
Mahon Jr., K.P.3
Shin, S.4
Kelley, S.O.5
-
20
-
-
44949212993
-
Two color RNA intercalating probe for cell imaging applications
-
DOI 10.1021/ja8008924
-
Stevens, N., O'Connor, N., Vishwasrao, H., Samaroo, D., Kandel, E. R., Akins, D. L., Drain, C. M., and Turro, N. J. (2008) Two color RNA intercalating probe for cell imaging applications J. Am. Chem. Soc. 130, 7182-7183 (Pubitemid 351813184)
-
(2008)
Journal of the American Chemical Society
, vol.130
, Issue.23
, pp. 7182-7183
-
-
Stevens, N.1
O'Connor, N.2
Vishwasrao, H.3
Samaroo, D.4
Kandel, E.R.5
Akins, D.L.6
Drain, C.M.7
Turro, N.J.8
-
21
-
-
77149166953
-
Synthesis and optical properties of cyanine dyes as fluorescent DNA base substitutions for live cell imaging
-
Holzhauser, C., Berndl, S., Menacher, F., Breunig, M., Göpferich, A., and Wagenknecht, H.-A. (2010) Synthesis and optical properties of cyanine dyes as fluorescent DNA base substitutions for live cell imaging Eur. J. Org. Chem. 1239-1248
-
(2010)
Eur. J. Org. Chem.
, pp. 1239-1248
-
-
Holzhauser, C.1
Berndl, S.2
Menacher, F.3
Breunig, M.4
Göpferich, A.5
Wagenknecht, H.-A.6
-
22
-
-
79960900073
-
In-stem-labeled molecular beacons for distinct fluorescence color readout
-
Holzhauser, C. and Wagenknecht, H.-A. (2011) In-stem-labeled molecular beacons for distinct fluorescence color readout Angew. Chem., Int. Ed. 50, 7268-7272
-
(2011)
Angew. Chem., Int. Ed.
, vol.50
, pp. 7268-7272
-
-
Holzhauser, C.1
Wagenknecht, H.-A.2
-
23
-
-
84861428195
-
DNA traffic lights: Concept of wavelength-shifting DNA probes and application in an aptasensor
-
Holzhauser, C. and Wagenknecht, H.-A. (2012) DNA traffic lights: Concept of wavelength-shifting DNA probes and application in an aptasensor ChemBioChem 13, 1136-1138
-
(2012)
ChemBioChem
, vol.13
, pp. 1136-1138
-
-
Holzhauser, C.1
Wagenknecht, H.-A.2
-
24
-
-
84866469369
-
Single labeled DNA FIT probes for avoiding false-positive signaling in the detection of DNA/RNA in qPCR or cell media
-
Hövelmann, F., Bethge, L., and Seitz, O. (2012) Single labeled DNA FIT probes for avoiding false-positive signaling in the detection of DNA/RNA in qPCR or cell media ChemBioChem 13, 2072-2081
-
(2012)
ChemBioChem
, vol.13
, pp. 2072-2081
-
-
Hövelmann, F.1
Bethge, L.2
Seitz, O.3
-
25
-
-
35448973736
-
Breaking up the correlation between efficacy and toxicity for nonviral gene delivery
-
DOI 10.1073/pnas.0703882104
-
Breunig, M., Lungwitz, U., Liebl, R., and Goepferich, A. (2007) Breaking up the correlation between efficiency and toxicity of nonviral gene delivery Proc. Natl. Acad. Sci. U.S.A. 140, 14454-14459 (Pubitemid 350003282)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.36
, pp. 14454-14459
-
-
Breunig, M.1
Lungwitz, U.2
Liebl, R.3
Goepferich, A.4
-
26
-
-
48749113674
-
Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo
-
Breunig, M., Hozsa, C., Lungwitz, U., Watanabe, K., Umeda, I., Kato, H., and Goepferich, A. (2008) Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo J. Controlled Release 130, 57-63
-
(2008)
J. Controlled Release
, vol.130
, pp. 57-63
-
-
Breunig, M.1
Hozsa, C.2
Lungwitz, U.3
Watanabe, K.4
Umeda, I.5
Kato, H.6
Goepferich, A.7
|