Preconditioning diabetic mesenchymal stem cells with myogenic medium increases their ability to repair diabetic heart

Stem Cell Research and Therapy

Volumn 4, Issue 3, 2013, Pages

  Khan, Mohsin ^a   Ali, Fatima ^a   Mohsin, Sadia ^a   Akhtar, Shoaib ^a   Mehmood, Azra ^a   Choudhery, Mahmood S ^a   Khan, Shaheen N ^a   Riazuddin, Sheikh ^a  

^a UNIVERSITY OF THE PUNJAB   (Pakistan)

Author keywords

Diabetic heart; Mesenchymal stem cells; Oxidative stress; Preconditioning

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; GLUCOSE; PROTEIN HGF; SOMATOMEDIN C; STROMAL CELL DERIVED FACTOR 1; TRANSCRIPTION FACTOR NKX2.5; UNCLASSIFIED DRUG; VASCULOTROPIN; HYDROGEN PEROXIDE; PROTEIN KINASE B;

ANG 1 GENE; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL HOMING; CELL ISOLATION; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSPLANTATION; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC CARDIOMYOPATHY; ENOS GENE; ENZYME PHOSPHORYLATION; GENE; GENE EXPRESSION REGULATION; HEART FUNCTION; HEART MUSCLE CELL; MEF2C GENE; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUSE; NKX2.5 GENE; NONHUMAN; OXIDATIVE STRESS; PARACRINE SIGNALING; PCNA GENE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; VEGF GENE; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DIABETIC CARDIOMYOPATHIES; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION PROFILING; MALE; MESENCHYMAL STROMA CELL; METABOLISM; PATHOLOGY; PHOSPHORYLATION;

ANIMALIA; MUS;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHIES; GENE EXPRESSION PROFILING; GLUCOSE; HYDROGEN PEROXIDE; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED C57BL; MYOCYTES, CARDIAC; NEOVASCULARIZATION, PHYSIOLOGIC; OXIDATIVE STRESS; PARACRINE COMMUNICATION; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 84878009661     PISSN: None     EISSN: 17576512     Source Type: Journal    
DOI: 10.1186/scrt207     Document Type: Article

References (42)

1. The development of heart failure in patients with diabetes mellitus and pre-clinical diastolic dysfunction a population-based study. From AM, Scott CG, Chen HH, J Am Coll Cardiol 2010 55 300 305 10.1016/j.jacc.2009.12.003 20117433
2. Activation of protein kinase C isoforms and its impact on diabetic complications. Geraldes P, King GL, Circ Res 2010 106 1319 1331 10.1161/CIRCRESAHA.110.217117 20431074
3. The promise of cell-based therapies for diabetic complications: challenges and solutions. Jarajapu YP, Grant MB, Circ Res 2010 106 854 869 10.1161/CIRCRESAHA.109.213140 20299675
4. Endothelial dysfunction, inflammation, and apoptosis in diabetes mellitus. van den Oever IA, Raterman HG, Nurmohamed MT, Simsek S, Mediators Inflamm 2010 2010 792393 20634940
5. Functional, cellular, and molecular characterization of the angiogenic response to chronic myocardial ischemia in diabetes. Boodhwani M, Sodha NR, Mieno S, Xu SH, Feng J, Ramlawi B, Clements RT, Sellke FW, Circulation 2007 116 31 I37 17846323
6. Plasticity of marrow-derived stem cells. Krause DS, Gene Ther 2002 9 754 758 10.1038/sj.gt.3301760 12032704
7. Plasticity and tissue regenerative potential of bone marrow-derived cells. Vieyra DS, Jackson KA, Goodell MA, Stem Cell Rev 2005 1 65 69 10.1385/SCR:1:1:065 17132877
8. The potential use of bone marrow stromal cells for cochlear cell therapy. Sharif S, Nakagawa T, Ohno T, Matsumoto M, Kita T, Riazuddin S, Ito J, NeuroReport 2007 18 351 354 10.1097/WNR.0b013e3280287a9a 17435601
9. Mesenchymal stem cell therapy for treatment of cardiovascular disease: helping people sooner or later. Trivedi P, Tray N, Nguyen T, Nigam N, Gallicano GI, Stem Cells Dev 2010 19 1109 1120 10.1089/scd.2009.0465 20092388
10. Cellular therapy for repair of cardiac damage after acute myocardial infarction. Cook MM, Kollar K, Brooke GP, Atkinson K, Int J Cell Biol 2009 2009 906507 20130765
11. Donor age and cell passage affects differentiation potential of murine bone marrow-derived stem cells. Kretlow JD, Jin YQ, Liu W, Zhang WJ, Hong TH, Zhou G, Baggett LS, Mikos AG, Cao Y, BMC Cell Biol 2008 9 60 10.1186/1471-2121-9-60 18957087
12. Enhanced apoptosis and senescence of bone-marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus. Li X, Liu L, Meng D, Wang D, Zhang J, Shi D, Liu H, Xu H, Lu L, Sun L, Stem Cells Dev 2012 21 2387 2394 10.1089/scd.2011.0447 22375903
13. Aging alters tissue resident mesenchymal stem cell properties. Alt EU, Senst C, Murthy SN, Slakey DP, Dupin CL, Chaffin AE, Kadowitz PJ, Izadpanah R, Stem Cell Res 2012 8 215 225 10.1016/j.scr.2011.11.002 22265741
14. Repair of senescent myocardium by mesenchymal stem cells is dependent on the age of donor mice. Khan M, Mohsin S, Khan SN, Riazuddin S, J Cell Mol Med 2011 15 1515 1527 10.1111/j.1582-4934.2009.00998.x 20041970
15. Pre-treatment of mesenchymal stem cells with a combination of growth factors enhances gap junction formation, cytoprotective effect on cardiomyocytes, and therapeutic efficacy for myocardial infarction. Hahn JY, Cho HJ, Kang HJ, Kim TS, Kim MH, Chung JH, Bae JW, Oh BH, Park YB, Kim HS, J Am Coll Cardiol 2008 51 933 943 10.1016/j.jacc.2007.11.040 18308163
16. Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells. Rosova I, Dao M, Capoccia B, Link D, Nolta JA, Stem Cells 2008 26 2173 2182 10.1634/stemcells.2007-1104 18511601
17. Improved survival of mesenchymal stromal cell after hypoxia preconditioning: role of oxidative stress. Peterson KM, Aly A, Lerman A, Lerman LO, Rodriguez-Porcel M, Life Sci 2011 88 65 73 10.1016/j.lfs.2010.10.023 21062632
18. Hypoxic preconditioning advances CXCR4 and CXCR7 expression by activating HIF-1alpha in MSCs. Liu H, Xue W, Ge G, Luo X, Li Y, Xiang H, Ding X, Tian P, Tian X, Biochem Biophys Res Commun 2010 401 509 515 10.1016/j.bbrc.2010.09.076 20869949
19. Differentiation of bone marrow mesenchymal stem cells induced by myocardial medium under hypoxic conditions. Xie XJ, Wang JA, Cao J, Zhang X, Acta Pharmacol Sin 2006 27 1153 1158 10.1111/j.1745-7254.2006.00436.x 16923335
20. Hypoxic preconditioning enhances angiogenic potential of bone marrow cells with aging-related functional impairment. Kubo M, Li TS, Kurazumi H, Takemoto Y, Ohshima M, Murata T, Katsura S, Morikage N, Furutani A, Hamano K, Circ J 2012 76 986 994 10.1253/circj.CJ-11-0605 22293445
21. Diabetes promotes cardiac stem cell aging and heart failure, which are prevented by deletion of the p66shc gene. Rota M, LeCapitaine N, Hosoda T, Boni A, De Angelis A, Padin-Iruegas ME, Esposito G, Vitale S, Urbanek K, Casarsa C, Giorgio M, Luscher TF, Pelicci PG, Anversa P, Leri A, Kajstura J, Circ Res 2006 99 42 52 10.1161/01.RES.0000231289.63468.08 16763167
22. Streptozotocin-induced diabetic rat-derived bone marrow mesenchymal stem cells have impaired abilities in proliferation, paracrine, antiapoptosis, and myogenic differentiation. Jin P, Zhang X, Wu Y, Li L, Yin Q, Zheng L, Zhang H, Sun C, Transplant Proc 2010 42 2745 2752 10.1016/j.transproceed.2010.05.145 20832580
23. Growth factor preconditioning increases the function of diabetes-impaired mesenchymal stem cells. Khan M, Akhtar S, Mohsin S, Khan SN, Riazuddin S, Stem Cells Dev 2011 20 67 75 10.1089/scd.2009.0397 20446810
24. Mesenchymal stem cells conditioned with glucose depletion augments their ability to repair infarcted myocardium. Choudhery MS, Khan M, Mahmood R, Mohsin S, Akhtar S, Ali F, Khan SN, Riazuddin S, J Cell Mol Med 2012 16 2518 2529 10.1111/j.1582-4934.2012.01568.x 22435530
25. Impact of diastolic dysfunction on the development of heart failure in diabetic patients after acute myocardial infarction. Aronson D, Musallam A, Lessick J, Dabbah S, Carasso S, Hammerman H, Reisner S, Agmon Y, Mutlak D, Circ Heart Fail 2010 3 125 131 10.1161/CIRCHEARTFAILURE.109.877340 19910536
26. Protective role of antioxidants in diabetes-induced cardiac dysfunction. Vassort G, Turan B, Cardiovasc Toxicol 2010 10 73 86 10.1007/s12012-010-9064-0 20458637
27. Diabetic cardiomyopathy: mechanisms, diagnosis and treatment. Hayat SA, Patel B, Khattar RS, Malik RA, Clin Sci (Lond) 2004 107 539 557 10.1042/CS20040057
28. Poor functional recovery after transplantation of diabetic bone marrow stem cells in ischemic myocardium. Govaert JA, Swijnenburg RJ, Schrepfer S, Xie X, van der Bogt KE, Hoyt G, Stein W, Ransohoff KJ, Robbins RC, Wu JC, J Heart Lung Transplant 2009 28 1158 1165 e1151 10.1016/j.healun.2009.06.018 19782602
29. Allogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathy via trilineage differentiating capacity. Quevedo HC, Hatzistergos KE, Oskouei BN, Feigenbaum GS, Rodriguez JE, Valdes D, Pattany PM, Zambrano JP, Hu Q, McNiece I, Heldman AW, Hare JM, Proc Natl Acad Sci U S A 2009 106 14022 14027 10.1073/pnas.0903201106 19666564
30. Effect of cyclic strain on cardiomyogenic differentiation of rat bone marrow derived mesenchymal stem cells. Huang Y, Zheng L, Gong X, Jia X, Song W, Liu M, Fan Y, PLoS One 2012 7 34960 10.1371/journal.pone.0034960 22496879
31. Bone marrow mesenchymal stem cells induce angiogenesis and attenuate the remodeling of diabetic cardiomyopathy. Zhang N, Li J, Luo R, Jiang J, Wang JA, Exp Clin Endocrinol Diabetes 2008 116 104 111 10.1055/s-2007-985154 18286426
32. Effect of bone marrow-derived mesenchymal stem cells on cardiovascular complications in diabetic rats. Abdel Aziz MT, El-Asmar MF, Haidara M, Atta HM, Roshdy NK, Rashed LA, Sabry D, Youssef MA, Abdel Aziz AT, Moustafa M, Med Sci Monit 2008 14 R249 BR255 18971868
33. Diabetes induced changes in rat mesenchymal stem cells. Stolzing A, Sellers D, Llewelyn O, Scutt A, Cells Tissues Organs 2010 191 453 465 10.1159/000281826 20130391
34. Hypoxic preconditioning induces the expression of prosurvival and proangiogenic markers in mesenchymal stem cells. Chacko SM, Ahmed S, Selvendiran K, Kuppusamy ML, Khan M, Kuppusamy P, Am J Physiol Cell Physiol 2010 299 1562 C1570 10.1152/ajpcell.00221.2010 20861473
35. Resveratrol improves myocardial perfusion in a swine model of hypercholesterolemia and chronic myocardial ischemia. Robich MP, Osipov RM, Nezafat R, Feng J, Clements RT, Bianchi C, Boodhwani M, Coady MA, Laham RJ, Sellke FW, Circulation 2010 122 142 S149 10.1161/CIRCULATIONAHA.109.920132 20837905
36. Activation of mitochondrial ATP-sensitive K(+) channel for cardiac protection against ischemic injury is dependent on protein kinase C activity. Wang Y, Hirai K, Ashraf M, Circ Res 1999 85 731 741 10.1161/01.RES.85.8.731 10521247
37. Mitochondrial ATP-sensitive K+ channels play a role in cardioprotection by Na+-H+ exchange inhibition against ischemia/reperfusion injury. Miura T, Liu Y, Goto M, Tsuchida A, Miki T, Nakano A, Nishino Y, Ohnuma Y, Shimamoto K, J Am Coll Cardiol 2001 37 957 963 10.1016/S0735-1097(00)01183-9 11693777
38. KIR 6.2 is not the mitochondrial KATP channel, but is required for cardioprotection by ischemic preconditioning. Wojtovich AP, Urciuoli WR, Chatterjee S, Fisher AB, Nehrke K, Brookes PS, Am J Physiol Heart Circ Physiol 2013 10.1152/ajpheart.00972.2012
39. The role of SDF-1-CXCR4/CXCR7 axis in the therapeutic effects of hypoxia-preconditioned mesenchymal stem cells for renal ischemia/reperfusion injury. Liu H, Liu S, Li Y, Wang X, Xue W, Ge G, Luo X, PLoS One 2012 7 34608 10.1371/journal.pone.0034608 22511954
40. Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis. Hu X, Yu SP, Fraser JL, Lu Z, Ogle ME, Wang JA, Wei L, J Thorac Cardiovasc Surg 2008 135 799 808 10.1016/j.jtcvs.2007.07.071 18374759
41. Hypoxic preconditioning of human mesenchymal stem cells overcomes hypoxia-induced inhibition of osteogenic differentiation. Volkmer E, Kallukalam BC, Maertz J, Otto S, Drosse I, Polzer H, Bocker W, Stengele M, Docheva D, Mutschler W, Schieker M, Tissue Eng Part A 2010 16 153 164 10.1089/ten.tea.2009. 0021 19642854
42. Angiogenic properties of aged adipose derived mesenchymal stem cells after hypoxic conditioning. Efimenko A, Starostina E, Kalinina N, Stolzing A, J Transl Med 2011 9 10 10.1186/1479-5876-9-10 21244679