Lipid nanoparticles with no surfactant improve oral absorption rate of poorly water-soluble drug

International Journal of Pharmaceutics

Volumn 451, Issue 1-2, 2013, Pages 92-94

  Funakoshi, Yuka ^a   Iwao, Yasunori ^a   Noguchi, Shuji ^a   Itai, Shigeru ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

High pressure homogenization; Lipid nanoparticle; Nifedipine Absorption; Poorly water soluble drug

Indexed keywords

DIPALMITOYLPHOSPHATIDYLGLYCEROL; NIFEDIPINE; PHOSPHATIDYLCHOLINE; POLYSORBATE 80; SOLID LIPID NANOPARTICLE; SURFACTANT;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG SOLUBILITY; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; SOYBEAN; SUSPENSION; ZETA POTENTIAL;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; DRUG CARRIERS; DRUG COMPOUNDING; MALE; NANOPARTICLES; NIFEDIPINE; PARTICLE SIZE; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLGLYCEROLS; POLYSORBATES; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; SOYBEANS;

EID: 84878008820     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.04.050     Document Type: Article

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